NorthWest Biotherapeutics Inc (NWBO)

[maverick_1]

FWIW: A Condensation of Issues for All

Appears that all the worldwide ANGST with BREXIT is now in better focus given the latest from:
1)Merkel viewpoints of filing 502 and negotiations.
2)Johson's abrupt reversal of being a candidate for PM and instead Gove or May.

AND with that set aside for probably 2 yrs (not surprising!) that is why markets reacted positively in last 4 days of trading worldwide.

Still outstanding what about the Russell event exactly one week ago. Don't see anybody has another plausible rationale than the one I posed HERE:http://investorshub.advfn.com/boards/read_msg.aspx?message_id=123543575

As for DCVAX-Direct: https://clinicaltrials.gov/ct2/show/NCT01882946

"Last updated: October 6, 2015"
"This study is ongoing, but not recruiting participants."
"No Study Results Posted"
"Purpose
The study comprises a Phase I component during which the optimal dose of DCVax-Direct for the treatment of solid tissue tumors will be identified, followed by a Phase II component to determine if the injection of DCVax-Direct into selected solid tissue tumors has the ability to reduce tumor growth.

Condition Intervention Phase
Locally Advanced Tumor Biological: DCVax-Direct Phase 1
Metastatic Solid Tissue Tumors Phase 2
Liver Cancer
Colorectal Cancer
Pancreatic Cancer
Melanoma
"Estimated Primary Completion Date:December 2016 (Final data collection date for primary outcome measure)"

ON DCVAX Direct: It would then appear that it is PROCEEDING PH1 rollED into PH2 for estimated Dec 2016 completion.

Given the public events since the Aug 2015 screening halt for DC VAX L as NWBO lead product and the ensuing alleged illegal stock price manipulation that there were MORE PRESSING PRIORITY for CEO LP: the execution of expanding manufacturing capacity in both Memphis and Swanston for Commercial launch and issues subsequently in terms of PhaseV
report; along with major dalliances and distractions with it's key shareholder Neil Woodford etc. NWBO clearly would not put funding into Direct until the above PRESSING PRIORITIES have ALL been addressed.is IMHO the only proper and plausible explanation. Bottomline: Shorts although critical DO DISTORT in every known instance to date to obviously serve their own interest. All one need do is READ about EACH and EVERY instance via Larry Smith NWBO reports re AFraudstein's ongoing 2+ yr skirmishes! Apt for most:IF "Thou protests too MUCH" SELL and move on and rid yourself of YOUR Cancer!vs spreading it!or seeking attention.

AND finally the pieces have fallen in place for a possible reason for screen halt on DC VAX L : manufacturing consistency throughout it's facilities re Flipper's post HERE:http://investorshub.advfn.com/boards/read_msg.aspx?message_id=123562714
HERE:http://investorshub.advfn.com/boards/read_msg.aspx?message_id=123580123

AND PERHAPS IF NWBO had recourse to a SEASONED PH3 FDA Clinical Regulatory Affairs Specialist as I've been citing, BEFORE 2015, none of which I see in two major 2016 NWBO press releases below... a screening halt may have been avoided??
1)May 2016 The new Scientific Advisory Board as seen HERE:http://investorshub.advfn.com/boards/read_msg.aspx?message_id=123519409
or
2)Jan 2016 new Bd of Dir Susan Bayh:DNDN and Wellpoint Bd of Dir.

Susan Bayh commented that “It is exciting to see the potential of DCVax, with encouraging clinical data to date, an excellent safety profile, a fast and efficient manufacturing process and a finished product that is frozen… key factors for commercialization potential. I’ve seen it all, in terms of the challenges with personalized immune therapies… what works and what doesn’t. I look forward to applying the lessons of my experience to help bring the DCVax technology to patients.”

PERHAPS with the hopeful wrapup of former coveted CIA's Ambassador Black into "Illegal Stock Price Manipulation mouthpiece orchestrated by AFraudstein this gets top billing amongst this: http://www.vanityfair.com/news/photos/2016/07/wall-streets-12-most-salacious-scandals. You can refer to my former comments HERE:http://investorshub.advfn.com/boards/read_msg.aspx?message_id=123445034
Special added note on Michael Milken: yes he was a pre IPOed KITE
key early Billionaire investor: http://www.fiercebiotech.com/r-d/updated-billionaires-back-kite-pharma-20m-raise-for-cancer-immunotherapies . AND the monetary effort expended on the alleged NWBO illegal stock price manipulation is TRULY A PITTANCE vs that needed for Dendreon simply due to the widespread level of institutional interest courtesy of first FDA approval on DC's. BUT DNDN's issues began with conceptualization/delivery and hence mfg costs compounded by again mgt's major judgement issues throughout the entire process culminating with drastically over estimating Provenge revenues with BOTH a large overheard nut despite downsizing! and the death knell of $620 mln DEBT! All of this in sharp contrast to NWBO's strategy and execution to date.

AND I do acknowledge the mammoth hurdles with a BLA that are unlikely to be resolved with NWBO staff as indicated HERE: http://investorshub.advfn.com/boards/read_msg.aspx?message_id=123579487

AND IF Sentiment, Flipper, Doc_Logic are spot on as it relates to the psuedo arm as well as PFS.... AHHHH how awful for Pyrrh with his
abysmal record to date and belated Mia Culpa.

It clearly appears that outside of myself, and the sole noted exception of RKMatters, NO ONE has cited ANY of the above STRATEGIC developments (seeing the trees and not the forest!), nor have exited at a profit and re entered shares for a small fraction unlike the denizens that populate this board and ALL at opportune times unlike the plethora of swing traders where my ignore list runneth over that populate this MB!

As good as the research done by Larry Smith and the prolific posters here, IMHO it does not by itself suffice for the investment pitfalls inherent (witness $12 precipice to current ~60'ish CENTS gully in last 12 mos! usually punished by the market when branded FUTILE and/or a company ABANDONS their lead product!). NONE of that happened to NWBO under the tenacious leadership of CEO Linda Powers. The key area where I think she misjudged was assuming her intelligence would more than suffice in navigating the complex FDA Regulatory maze versus that of having an experienced PH3 consultant to rely on.

Moreover many here have never had exposure PRE- NWBO in dealing with the bounty of landmine hazards associated with emerging BioTech investing. Additionally,NO ONE factored into account for the utter depravity of snuffing out creativity via the massive, pervasive and well endowed network of alleged wrongdoing in the BioTech sector by the likes of AFraudstein;Cramer;Shrekli;Milken; powerful Hedge Funds.... all depicted thru desperatecapture.com

So, unless and until we see a major NWBO news announcement, IMHO the shares which I believed have bottomed and have some element of buoyancy given the harshness which is unjustly accorded: which would have been justified IF there was futility: an unexplained screening halt is very different and it's duration is approaching a year! Furthermore, NO sane company would in it's fragile cash flow state, invest heavily in manufacturing during that entire episode unless there is a rainbow at the other end. Nor would CEO Linda Powers venture to re-appear at those scheduled Sept 2016 trade events in Europe as Flipper posted.

Although institutional ownership is ~42% as of March 31, 2016, every institutional investor is DRASTICALLY UNDERWATER. What will they do??????

What will the shorts(both legal and Naked Shorts) do??? see: http://investorshub.advfn.com/boards/read_msg.aspx?message_id=123544286

Although the below was posted close to a week ago and RE-EMPHASIZED...NO cogent replies yet:

maverick_1 Monday, 06/27/16 08:55:38 PM
Re: sentiment_stocks post# 65658
Post # 65662 of 65949 Go
Expanding on my theory, barring a plausible alternative being presented here, is how I see the short's main concerns being locking in a profit as the incremental below say the 60 cts level is small,, relative to diminution, to vaporization of it, to possible losses are the outcomes depending on one or more or all of the following materializing in the near future:

1.NWBO will find funding! ANGEL INVESTORS like Dennis Mehiel; to even possibly Baker Bros (as posted over 2 yrs ago:"Felix received a PhD in Immunology from Stanford University.")
2.Ten months and counting on resolving the screening halt possibly due to mfr consistency that is in, hopefully some end stage of resolution.
3.Former FBI Mr. Black's (?) apparently been at it for six months.
4.Down towards the final stages of Ph3 DCVAXL
5.Prelim's and staging for Direct Ph2 beyond just MD Anderson
6.Perhaps finalization with three partners as it relates to Checkpoint Inhibitors
So IMHO the Shorts are playing with FIRE with the OVERTIME.

And WHY the priority in closing out Naked Shorts relates to #3. Why it isn't obvious to one and all at this point in time is beyond me. It would also serve a twin purpose in NOT showing their hand. Once investors see in black & white a decline in short interest, those informed investors will follow with buying as it signals IMHO the short's view that the bottom has been reached and trying for more is realistically asking for trouble as indicated in the first paragraph.

Should the above settle in logically with you, I believe that is what is happening and we are clearly in the early phases of an inflection point to where it becomes the law of diminishing returns for the shorts IMHO.

The above are what readily comes to mind as I need to address low blood sugar levels (slept but 2 hrs!; haven't really eaten except in the last 5 minutes with yogurt w/blueberries and a sliced banana and readying for a first stab at Sichuan Chicken)

NWBO: UNJUSTLY MALIGNED & MANIPULATED IMHO.

Surely it has been a mentally and financially painful and taxing experience to the point for some of utter despair.... to that of wipeout, So hopefully you've have learned through this experience for the future. And every biotech has some uniqueness but there are loads of similar characteristics. That's why, on balance, there are few long term successful investors in this sector as well as why Shorts do have a field day.

Clearly it takes a lot to deal with ALL of the above.
Keep that in mine when venturing further into Biotechs.

At the very least:
Have a Safe and Happy Fourth of July!