NorthWest Biotherapeutics Inc (NWBO)

[Pyrrhonian]

I'm getting bored :)

How do you reconcile your DMC finding futility with Linda Liau’s statement that EVERYONE is living longer?

PFS does not = OS

For Linda Liau’s statements to be truthful, that means that the trial median needs to have a SIGNIFICANTLY high OS in both arms. Her statements suggest that they can not be falling short on their protocol assumptions.

If there are an excessive amount of PFS events in DCVax-L group then the DMC can recommend a halt for futility. Excessive is 2:1. By last summer there was probably around 180 or more PFS events to look at. If 120 came from DCVax-L group and 60 from placebo that's bad.

It is interesting Liau was all about OS in her talk. And she looked exceptionally nervous (fake smiles, fake laughs, stumbling through sentences--not really like her other talks I've seen).

Look just stay long and prosper. When CYTR hits you can buy more NWBO at $0.48 ;)