NorthWest Biotherapeutics Inc (NWBO)

[Doc logic]

Doktornolittle,

Hope I'm not out of place here but the lower dose, multiple site injection method is how NWBO sought to overcome this issue. The phagocytation of DCs with self antigen near the site of injection left small numbers of DCs to travel to the lymph zone. Good thing that various studies have shown that only small numbers are needed to activate a robust immune response. Eventually this response will be improved upon with isolated, tumor specific activated T-cell subsets that are the most active tumor killers and suppressors. Best wishes.