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Re: AVII77 post# 75682

Friday, 03/25/2016 3:47:53 PM

Friday, March 25, 2016 3:47:53 PM

Post# of 425648
That is helpful. Then the total number of FIRST EVENTs will be a lot less and therefore it is likely that the guidance of the company indicating they do not expect a stop at interim may be driven in part by this.

In other words, the trial may be going brilliantly, but due to the much lower number of FIRST EVENTS that drive the primary endpoint they may not reach the strong statistical significant that is required.

Thoughts

Also thanks AVII, raf, JL, HD and others for their very thoughtful posts

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