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Re: flipper44 post# 54640

Monday, 02/22/2016 1:22:42 PM

Monday, February 22, 2016 1:22:42 PM

Post# of 711611
But is there a difference, in terms of alpha spend, between a 1st interim look where only futility can be reported/(stop-recommeded) by the DMC, and a 1st interim look where the DMC is also allowed to come back with some other statement related to efficacy... such as, "go for it" with it being, for example, some form of early or accelerated approval for the entire patient population or some subgroup(s)?
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