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Re: Doktornolittle post# 54590

Sunday, 02/21/2016 1:49:26 PM

Sunday, February 21, 2016 1:49:26 PM

Post# of 702428
"I guess Pyrrho came up with some alter scenario to flat out needing to redo the trials if Optune is an issue. Some change to OS as the primary endpoint or something. I'm not following, but thought I had short-circuited the complex discussion in the Celldex feedback scenario... but maybe not."

I didn't say that quite right. Maybe I shouldn't have tried since there is a large book's worth of discussion between you and Pyrrho on the topic of Optune. A book I chose not to read. Not sure if you debated the Optune-Celldex dimension yet. If not, it does seem worth debating if Optune is worth debating.

Celldex is probably already using OS as the primary endpoint, so if that somehow makes Optune a non-issue, then I guess Celldex becomes irrelevant. But you guys must be awfully deep in the details to reach an argument that Optune would effect DCVax-L but not Celldex's vaccine.

It has to be the same issue or non-issue in my opinion. Non-issue for both IMO.
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