NorthWest Biotherapeutics Inc (NWBO)

[Doktornolittle]

Just saying that if Optune has any effect on NWBO's path to approvals then it would have to also effect Celldex. My understanding is that Celldex may currently be in efficacy review for their vaccine for new GBM. Their trials didn't include Optune in the control group as far as I know, so any decision in the direction of an early approval would verify that Optune is a non-issue.

Of course Celldex may not be in efficacy review... and even if so, the most likely outcome will be a very low-key "continue" with no other information. In that case there would be no reveal concerning Optune or anything else...

??? but maybe even a continue, if in fact there is a review for efficacy, would indicate that Optune is a non-issue. Why continue the trial with no Optune in your control group if such would be required ultimately for approval? Wouldn't all that get hashed out now if an efficacy review is in fact going on?

I guess Pyrrho came up with some alter scenario to flat out needing to redo the trials if Optune is an issue. Some change to OS as the primary endpoint or something. I'm not following, but thought I had short-circuited the complex discussion in the Celldex feedback scenario... but maybe not.