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HDGabor

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HDGabor

Re: jessellivermore post# 36883

Sunday, 10/19/2014 12:17:11 PM

Sunday, October 19, 2014 12:17:11 PM

Post# of 426729
Hi JL,

I did not stated that the trial can not be stopped for efficacy after a quarterly review. I said quarterly review and interim analysis are not the same. Otherwise why they predefined the interim analysis. My view that for efficacy stop the quarterly review is not enough, they have to do the analysis also (check the stopping rule).

I did not say that none of the study was stopped before predefined interim analysis. I said I and nobody else on this board could find an example. I will be so happy if anybody could find an example, but until that we have to assume that no stop before 967 events.

Maybe ultima materia is exist ...

Pele scored 4 goals. In exchange, please do me a favor and find the study stopped before predefined interim analysis.
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