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Re: john1045 post# 10071

Wednesday, 05/14/2014 1:21:46 PM

Wednesday, May 14, 2014 1:21:46 PM

Post# of 703377
Before I swim along….

John, I think your points about the strength of results cannot be understated.

Just recently, Evaluate posted a link to a 2013 FDA webinar, wherein a major point was made deep in the audio -- in passing; that, very early stage moderately sized trials can be used to substantiate treatment approval where the results are "dramatic enough."

I think Dr. Chuck's replication point is well taken, but where:

"increase in the ratio of the pSTAT-5 ratio (post to pre DC vaccination) from IL-2- stimulated cytotoxic T-cells following DC vaccination reduces the risk of death in vaccinated patients by 5.45 times "

I think what UCLA deemed as reproducible results may present a "dramatic enough" persuasion.

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