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You're not 'getting' screwed. You're screwing yourself!
You must be lonely ;)
Do you think anyone really believes you?
Dennis the menace. That's a kids show right Good grief how old are you (I mean the number of years that have passed since you were born, not mentally, mentally I estimate you at 8) are you 12? 13?
Dennis the menace LMAO last time I heard something like that I was 12
LOL... you have no clue.
Every poster has 15 minutes time to edit a post when he she accidentally posts something.
What counts is the final post and that was without that part as you can find here
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=172876605
But leave it to that frustrated douchebag to twist the words I never used in my final post
The frustration of Anavex runs so high here that now what someone said in an initial post prior to the final post is of life-threatening importance.
no, I think someone is really frustrated. the sad thing is he thinks that lashing out at other posters will change his financial situation.
wow what a comeback. I'm stunned, did you ask your Mommy what you should write next to the mean person on the internet?
good for you. Now Im going back to make some real money dont be late for your McDonald's shift now. Dont quit your day job!
No you didn't you are making shit up all the time here, loser
lol I will post and stay here as long as I want. Im looking forward to having many pleasant post-exchanges with you hahaha
ooh you are so frustrated about Anavex. How much money did you lose so far? Come on tell us 2 months' salary so $ 2000? 4-month salary so $ 4000
Can't pay the rent to Mommy for you basement anymore ooooh that sucks
hahahahaha
I have never said that asswhipe I said this: "Its all about present and future market cap." you added that part and now pretending I said that because you are a loser
link to the post where I said that?
Anyway for your investment ABC: market cap = O/S x stock price
here is my post https://investorshub.advfn.com/boards/read_msg.aspx?message_id=172876605
No chance of that happening, because of the outstanding shares. It will limit the upside for NWBO no matter what you think.
As for AVXL if approval happens it become a rocket. No comparison
you really are a loser hahahahaha what a loser
Why do you ask me? Google it yourself how the market cap of a listed company is calculated. Please report to your elementary school teacher for basic mathematics.
You really are a dumb ass. First, keep denying AVXL changed endpoints then you ask me how a market cap is calculated. I suggest that biotech investment is not for you dummy.
Last-minute changes lead to mixed response for Anavex’s blarcamesine
https://www.clinicaltrialsarena.com/comment/mixed-response-anavexs-blarcamesine/
Additionally, the original endpoints of the trial were shifted from the change from baseline in RSBQ and CGI-I scores to AUC responder analysis of these scores. These changes were only made in the FDA’s clinical trial database two weeks prior to the announcement of the AVATAR trial results
Submission will happen on Monday and acceptance within two weeks and approval as early as November.
In any event NWBO will out pace AVXL over the next 4 weeks. IMHO.
What you are referring to is the SAP Statistical Analysis Plan not the SPA which is a different thing entirely.
Next is Rett will be the first NDA and the first approval.
My advice in my previous post is to wait until after MHRA approval for DCVAXL which I expect half January or before to arrive. That plus some other expected news (such as news about their announced combo trials with upfront payments) should turn NWBO into a minimal x5 bagger so around $5. I can't make any promises for the next few weeks but we are in a nice uptrend which I do not expect to end. UK approval is a given.
I too will buy back into Anavex again on the condition that they have a more clear path for approval. This could mean the FDA-bought-in Anavex SAP for an AD P3 trial on which they are likely to be approved or a journal article outlining how they got the assumption they have met the endpoints. Im not gambling on an AA for AD. If that means I will miss a big bang in AVXL stock in the IMO highly unlikely situation that there will be AA then so be it. Im only investing in nonrevenue biotech companies with a scientifically validated path forward for their drug.
Let's revisit this post on September 16, 2024. That's the day long-term capital gains kick in. I'd be willing to bet AVXL ends up the superior investment choice
My recommendation is to sell AVXL and buy all NWBO shares you can get your hands on. You can thank me in 3 to 6 months.
no matter how many times you provide overwelhming evidence exwanneassh the IT guy from Georgia will never admit to anything.
exwanneassh reminds me of Shaggy
She even caught me on camera (It wasn't me)
She saw the marks on my shoulder (It wasn't me)
Heard the words that I told her (It wasn't me)
LL has clearly been using DCvax-L as a generic term
You are absolutely right this whole instant approval for tissue-agnostic tumors is a figment of ATL's imagination and not based on any FDA regulation outlined here https://www.fda.gov/media/162346/download
Its Atlanta's recurring fantasy based on ChatGTP research.
Ex why did you lie about this? What kind of person does this? :)
sorry I dont understand gibberish
agreed
That article is from Feb 2022.
The point is the trouble that Anavex is in to get AA for this AD trial.
-Changed endpoints late-stage
- No bought-in clear SAP, changing the SAP by every next PR
-Missing a coprimary endpoint which doesn't support the met all primary and secondary endpoints claim (for making that previous statement I personally see Anavex being held legally liable but that is for another discussion)
- Controversial in the manner in which they statistically analyzed the data within the last PR mathematical errors.
- Post hoc data digging
If Anavex's new SAP they have apprearently now decided on since Nov 2022, is accepted by the FDA then their Phase 3 trial has a good chance of being successful.
? sorry I dont understand gibberish. The rest of your post is pure frustration and fantasy.
I have no position in Anavex short or long. But will buy into Anavex after their new SAP as what they appear now (since yesterday's PR) are going for has been bought in by the FDA and they started their P3 AD trial.
No everything that does not fit your investment thesis is FUD even reality, according to you.
yes lots of questions remain unanswered.
Ok
Anavex down 16% as criticism on changing endpoints in late-stage trial mounts
my main concern relates to validity whether it is post hoc vs. pre-specified.
? gibberish
Anavexs SAP and original endpoints have not been bought in by the FDA hence their change in PR language and data presentation from their last one and the one before that. Why do you think the SP reacts accordingly with what Im saying?
I have the same question, but given the reasonable assumption that Anavex does not have an agree upon SAP with FDA for AD, it might give Anavex an opportunity to negotiate one through discussion with FDA or a foreign authority which is disclosed in today’s PR:
All prespecified clinical endpoints were analyzed using a mixed model for repeated measures (MMRM). The MMRM analysis method is the convention used for regulatory filings and discussions with regulatory authorities are in preparation.
This MB is not for anyone to influence anyone else. Its to exchange ideas and discuss the ongoing Anavex trial. My advice to you and any other MB poster is not to be influenced by any other poster but to conduct your own due diligence. Good luck with your investment endeavor.
Just because someone does not post too many times on the Anavex board does not make that person incorrect.
The ongoing OLE will only confirm yesterday called surrogate new endpoints. You can make the illations from 100 datasets or 1000 datasets it doesnt matter if these datasets point to the same statistical conclusion of a non-existing SAP. The problem/challenge Anavex is facing right now is best described in this post
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=172827280
No its a genuine investment tip for retail investors. Call me out in 3 to 6 months from now and call me out now if anything I said about Anavex is not based on common sense.
Or are you not in it to make money? Also, you would insult my intelligence if I was under the impression that 5 new retail shareholders would do anything for NWBO stock price. NWBO will see a huge investor between now and 3-4 months and it's not going to be 5 formal Anavex shareholders.
But thank you for contributing this much power to me ;)
I agree with your analysis. Thank you for your reply
I understand its difficult to cope with the situation Anavex finds its self in at present. My recommendation is to sell AVXL and buy all NWBO shares you can get your hands on. You can thank me in 3 to 6 months.
After an incredible return on NWBO shares, you can sell some of those and buy a small portion back in Anavex. I do believe they will get ADD approved if their SAP for the P3 trial is bought in by the FDA and in a few yeard after their P3 trial has been concluded.
agreed
Can never trust a guy with two first names