https://gritdaily.com/cancer-therapy-oncovirs-hiltonol/ Looks pretty promising to me

Flagyl is trade name for metronidazole and cheap..10 bucks or so. Oral vancomycin is about 40 bucks. Vancomycin is not well absorbed when taken orally so usually given IV for systemic infections. But since c diff is in the gut, oral administration is just fine for that.

Gary, you need your antibiotic for C diff. Metronidazole or vancomycin usually works. I would also take 2 tbsp of pepto bismol (bismuth) after each loose stool up to 5 doses a day https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421188/

In addition I would take a probiotic supplement to repopulate your gut with good bacteria.

I am astonished that geniuses like you and ex are spending all of your valuable time here instead of running a company that we can safely invest in. Certainly you have offered your expertise to management about the proper way to conduct business. As it stands, the company is making me so anxious, I could only nap for an hour and a half today after walking the dogs in the blazing heat.

https://westnsurg.org/cloward-award/ in case you were interested in the person

The last 4 digits of my account are on the email. No teenager is around to show me how to black it out.

What are you talking about? You said this was safer than burying money in the back yard. You said all my financial dreams would be realized. You said I’d be able to buy the Cleveland Guardians. You said I could winter in a tropical paradise. You did! You did! 😉

Another request from Schwab to borrow NWBO shares for shorting today. And yet they won’t let a co worker buy this “ penny stock”. Any broker that can explain this?

German is not my primary language but in regards to your reasoning......Das ist ganz verruckted. It is only damage if you sell low. If you are deciding this before the MHRA decides then you are making a premature decision.

Schwab is persistent. Several months ago they asked to loan my shares (there is only NWBO in my account). I called them up and said no very emphatically. April 6 another email arrives asking to lend my shares to parties looking to short “selected stocks”. Maybe someone who has a longer background in investing can explain what types of stocks are targeted. Just seems unusual for little ol NWBO to be such a popular target.

Shouldn't you be out getting the fields ready for planting?

Nice try, but that quote is referring to the Optune device

.....and now I see that others have already pointed this out. I wish I had some more dry powder, because clearly this nemesis is here with ill intentions. It's a big universe and this entire drama is just a spit in the ocean, but there is no justification for flat out lying.

Since approximately 70% of antibiotic use has been used as feed supplements to promote weight gain for beef and to prevent infection in overcrowded chicken factories, which is where the resistance is selected I don’t believe there is much concern about selecting more aggressive cancers through vaccine use. The cancers currently evolve to evade detection and resist chemotherapy anyway. Maybe in the future there will be a catalogue of cancer antigens so complete that a custom vaccine could be “ordered”. In the meantime, I think we will have to rely on our individual immune systems.

And one of the inventors is J Kelly Gangei. He is the CEO of AmplifyBio, that offshoot company of Batelle, who is advertising for a senior process engineer so that the company can "change the world".

https://finance.yahoo.com/news/amplifybio-ceo-j-kelly-ganjei-120000387.html

If this is from "Wall Street" then you are correct that they don't want anything to do with educating about DCVax. Not a word about dendritic vaccines. Posted 1-10-24

https://www.biopharmadive.com/news/pharma-outlook-2024-obesity-cancer-ira-alzheimers/704138/

Merck and Bristol Myers have dominated cancer immunotherapy. Who wins oncology’s next era?
Merck’s Keytruda and Bristol Myers’ Opdivo have dominated the cancer treatment conversation for a decade. Both will reach the end of their patent-protected monopolies as soon as 2028 in the U.S., pushing the two drugmakers to explore commonly used ways of extending market exclusivity, like combination treatment and formulation changes.

Read More in Pharma

But drugmakers are also working hard to find what comes next. Researchers have struggled to develop successor medicines that stimulate immune attacks on tumor cells as Keytruda and Opdivo do, with Bristol Myers’ combination drug Opdualag an exception to the rule.

The flurry of dealmaking around antibody-drug conjugates in 2023, headlined by Pfizer’s $43 billion acquisition of Seagen, is a sure sign big pharma sees these targeted therapies as a significant new opportunity. Radiopharmaceuticals, which deliver radiation directly to tumor cells, are also drawing significant investment.

Bispecific antibodies, which help immune cells find and destroy tumor cells, have proven successful in treating blood cancers like multiple myeloma and lymphoma. They’ve had less success in solid tumors, although they are still being tested in prostate and lung cancer.

After years of disappointment, cancer vaccines are finally making gains, too. The messenger RNA technology employed by Moderna, BioNTech and others can be used to create personalized treatments that stimulate an immune response to patients’ tumor cells. Key data from Phase 3 trials of Moderna’s Merck-partnered vaccine in melanoma and lung cancer could come in the next couple of years. — Jonathan Gardner

I agree that AmplifyBio may be part of the game. As your link mentioned, the CEO J. Kelly Ganjei of Ampfify is formerly of Cognate. On LinkedIn he is reposting the job for Senior Process Engineer. https://www.linkedin.com/jobs/view/3713989716/ .......What You’ll Do Here:

Responsible for managing the transfer of CGT manufacturing processes from our clients into the AmplifyBio GMP facility.
Provide leadership and training of the manufacturing staff on cell manufacturing processes and equipment. Support the manufacturing staff during technical transfer, start up and in routine processing.
Works effectively with the other operational groups to ensure that all GMP requirements are met for the implementation of processes into the AmplifyBio facility.
Works closely with the Supply Chain, Quality Control, Validation, Engineering, and Quality Assurance functions internally to ensure the facility meets all appropriate standards and cell therapy manufacturing processes are performed per client and GMP requirements.
Coordinates Manufacturing timelines and deliverables through Joint Project Teams, Program Management, and other functions as appropriate.
Provides support during facility start-up and activities associated with future expansions.
Provide support on equipment implementation and qualification.
Author and reviews relevant documentation for cell manufacturing operations and equipment.
Position may require some travel.


We Would Love to Hear from You If:

MS or PhD in biological sciences or engineering or BS degree in scientific field plus at least 8 years of experience.
Minimum of 4 + years of experience in Manufacturing or Development roles with more than 2 years in a drug product development and manufacturing function at a biotechnology or pharmaceutical company with direct involvement in the process to achieve early development milestones and successful product licensure.
Knowledge and experience in leading a team in transferring a process into a new facility (such as from Process Development, CMO, or Manufacturing).
Experience with aseptic processing and cell therapy manufacturing.
Experience in leading meetings, teams, and projects.
Demonstrated management experience including employee development and leadership.
Experience with issues related to manufacturing is required.
Knowledge of current requirements for cGMPs required and knowledge of GLP/GTP/GCP is a plus.
Experience with regulatory submissions or supporting regulatory filings.
Forward-thinking and creative with high ethical standards.
Team player with leadership skills with ability to influence others to achieve successful manufacturing campaigns and to enable regulatory product approvals.
Well organized and self-directed.
Strong interpersonal skills with an ability to communicate to people at all levels of an organization.


Desired But Not Required:

PhD in related field of study.


At AmplifyBio, we're committed to growing and empowering an inclusive community within our company and industry. Therefore, we hire and cultivate diverse teams of the best and brightest from all backgrounds, experiences, and perspectives across our organization. Research shows that oftentimes women and minority groups only apply to open roles if they meet 100% of the listed criteria. AmplifyBio encourages everyone — including women, people of color, individuals with disabilities and those in the LGBTQIA+ community — to apply for our available positions, even if they don't necessarily check every box on the job description. Hire for attitude and train for aptitude creates unique opportunities to build strong teams of smart, motivated individuals who love what they do.


AmplifyBio is an equal opportunity employer, and we value diversity at our company. We don't discriminate on the basis of race, color, citizenship status, national origin, ancestry, gender (including gender expression and gender identity), sexual orientation, age, weight, religion, creed, physical or mental disability, marital status, veteran status, political affiliation, or any other factor protected by federal, state, or local law. AmplifyBio will not tolerate discrimination or harassment based on any of these characteristics. If you have a disability or special need that requires accommodation, please let us know during the recruiting process. We are committed to the safety and wellness of our employees and customers. Therefore, COVID vaccination is required.


Why You Will Love Working Here:



We take the health and happiness of our employees seriously and consistently evaluate new ways to Amp up our benefits to provide an amazing place to work. From a wellness program to financial planning and legal assistance, we make sure to take care of our own.
Health, Dental, and Vision insurance that starts on your first day at AmplifyBio!
Competitive Compensation Package
We take work-life balance seriously and we back it up with an UNLIMITED PTO policy.
Life and AD&D insurance
Supplemental insurance
LiveHealth Online
Smart Shopper (helps you shop for better medical care and earn cash rewards while you save)
Generous paid parental leave
Wellness and Self-Care Programs
401(k) match
Tuition Reimbursement
EAP/work-life support system
A fun work environment where everyone’s voice matters.
We are just getting started! More benefits on the way!
An Opportunity to Change the World!!!

The CEO sounds pretty darn optimistic
I don't think LP is going to be held hostage by anyone. My opinion only.

Captain, do you recall the software and company that will provide all of the data tracking from harvested tumor to vaccine production to delivery and administration? Was is something referencing autologous?

The portfolio includes Zalmoxis, an allogenic T-cell therapy as an add-on therapy to support stem cell transplantation. It was approved in Europe through a conditional marketing authorization in 2016 but subsequently withdrawn by MolMed after Phase III clinical trial results showed that the drug offered no benefit on disease-free survival.

We can do this all day Ex, but the sun is shining and its time to get out of here.

General
Unless otherwise specifically indicated, Miltenyi Biotec products and services are for research use only and not for therapeutic or diagnostic use.


Ex give it a rest

https://www.miltenyibiotec.com/US-en/regulatory-notes.html

Of course, only to be used for research.

https://www.otc.financial/list-of-market-maker-signals/#google_vignette

just in case anyone needs a refresher

https://endpts.com/merck-gives-few-details-on-2024-restructuring-plan-for-manufacturing-network/

Merck is getting ready for something apparently but not saying exactly what that is

Just click on ignore under it's profile picture..3rd block down.

This one is interesting too. https://www.researchandmarkets.com/reports/5899158/lerapolturev-pembrolizumab-emerging-drug#rela2-5899244 "Lerapolturev - viral immunotherapy based on the Sabin type1 polio vaccine"

I was curious too. https://pubmed.ncbi.nlm.nih.gov/12727832/#:~:text=Intradermal%20injection%2C%20as%20opposed%20to,suppresses%20tumorigenicity%20of%20tumor%20cells

https://siteselection.com/issues/2022/jul/why-biotech-firms-like-buckeye-land.cfm

The article above just describes the biotech development in and around Columbus which includes New Albany,

My brother lives in New Albany. I asked him to check with his contacts about any possible dealing with NWBO. This was a month ago or so. No response from him yet. May have to bug him again and see if discovered anything.

I know 2 people born on Christmas Eve. One is named Christina and the other is named Carol, which is sort of fitting for the holiday. Just curious though, was one of the wise men named Robert?😜

Well doggone.....I am the 5th of 11 children. Our attempts to run an inherited family business are complicated by opposite views on a multitude of issues. So nothing said here bothers me. If people want to talk smack....talk away. If promises were made with incomplete information.......welcome to life. Just say, "I changed my mind, going to keep posting". Ultimately, none of the "experts" here badmouthing the company have a clue what the issues really are, and none of the optimists have a clue either. Lots of good educated guesses, but we are all just going to have to wait for the book to come out.

Paid advertising?? You can do better than that, I'm sure

Whoa, I said I had 3 different accounts. Schwab didn't specify which they wanted to use. In any event, I replied that they are NOT to lend any NWBO shares.

I have Roth, rollover and reg account. In their letter they say….shares are typically loaned to short traders. I dunno. Things look crappy until they don’t it will soon be 3 years for me since I started buying. Not a long but not a newbie.

Another email today from Schwab asking to borrow my shares. And all I have with Schwab is NWBO

My goodness, this is somewhat of a feisty frantic Saturday morning. Actually quite humorous. Personally I think Willie Nelson “Blue Skies” should be the prevailing attitude.

Buy low, sell high
Listen to Warren Buffet
Be patient

Captain and Danish,

I am a daily lurker here and avid craft beer fan. Captain knows I am not far away and I too would like to meet the Oracle of Denmark.

Picked up 4k more @.49 today. Not a long, not a newbie.....kind of a tweener

It's TURTLES-all the way down!

Actually, the human body is one fascinating piece of machinery. How all the different processes of blood clotting, tissue healing, reproduction, energy production, stem cells and cell differentiation, telomeres and this other thing about cancer antigen recognition; can't really convince myself that it evolved from nothing. And still can't imagine why we are here.

Thanks Loyal and Iron.

Regarding the 1st panel at the moonshot meeting; there was an attorney on the panel who was a greater than 5 year survival from GBM. Does anyone know with what and how he was treated?