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Kiwi.....Nothing wrong with the numbers as you said. I did have excess body fat thanks to my Ben and Gerry's Covid diet so I managed to melt that off by avoiding carbs and burning fat for energy. That's what happens when you become fat adapted.
I stopped taking the Lisinopryl because my BP normalized
It will be interesting to see what my personal lab rat lipids look like in a couple weeks......as you may recall, I put myself on a super low carb way of eating. Mostly high fat meat, dairy, and eggs. Prior to this, my standard American Diet lipids had me at LDL=95, TRIGS=40, HDL=80. My BP was hanging around the hypertension levels of 140/90 and they prescribed low dose Lisinopryl. At the 6 month mark, I had LDL=200, TRIGS = 48, HDL=89.......no more Lisinopryl as my BP hovers in the 120's/80s....... so I'll see the vampire next week and see what happens
Let's not forget, these indications assume a certain level of ability to tolerate statins....... a case can easily be made that a patient does not tolerate something.
Reimbursed indication: Icosapent ethyl is reimbursed in the treatment of patients aged 18-80 years with established cardiovascular disease and BMI ≥27 kg/m2, on treatment with a high-potency statin at the maximum tolerated dose + ezetimibe, who have achieved target LDL cholesterol levels (<70 mg/dL), and have residual hypertriglyceridemia (TG ≥200 mg/dL) not explained by other causes and confirmed in at least 3 determinations despite good dietary adherence.
I see this in the document link.
If only we could transfer the CVD indication to MND-2119 or LR-EtEPA and Icosapent Ethyl only for the Trig lowering......... then the USA would be back.
I agree JRoon...... I was just looking for confirmation that they have partnership rights to those formulations. My simple mind wants it spelled out clearly....... that gives me additional hope that there is a pipeline.
Oooh..... good find Sleven
This will be similar to a Harris interview where they'll know the questions in advance because they get to choose them. The difference is that AMRN will answer the questions that they choose.
We need to submit an easy yes or no question like " Does AMRN have formulation rights to MND-1 (if I have that correct )"
We keep speculating that they do but it's never been clearly spelled out as far as I have read.
Excellent..........my dog was right again.....she's the best!
My dog........she can smell what Sarissa is cooking...... although up to this point, it stinks!
What's that phone number again for AMRNholics anonymous (AA) ? Just bought another 3200 shares after consulting with my dog. She said somethings brewing!
C'mon Sarissa.......do it!
Some sort of injunction Rose would be a beautiful thing..... we'd jump to $10 on that news.
Yes.....I'm a bit soured on trials as you can imagine....... when you have great comprehensive trial like Reduce-It which validates a trial like Jellis and you struggle to get market acceptance by the healthcare industry, it just shows how flawed the system is. Money talks. Do what Big Pharma wants or they stop funding your research or sponsoring your weekend symposiums. If you can't beat them, you have to sell to them.
Kiwi, I would say these studies were provided to the world by Captain Obvious. Why would we even need 1 double blind placebo controlled study showing a drug engineered for weight loss would also be associated with reduced risk of cardiovascular events and diabetes?
Should we have a double blind placebo controlled study showing jumping from an airplane without a parachute is associated with higher mortality rates?
This is why the FDA and drug claims crack me up....... of course a weight loss drug if it works can say "Reducing the risk of major cardiovascular events in patients with type 2 diabetes and established cardiovascular disease".........
That's like me coming up with a pill that contains either air or water and claiming "Reducing the risk of major cardiovascular events in patients with type 2 diabetes and established cardiovascular disease if taken while on a whole food diet with moderate exercise" In addition, my pill would have an incredible safety profile across all populations inclusive of Male's, Females, and all Genders in between.
I will set up a go fund me page and and am open to all investors. Bitcoin accepted.
Much appreciated Capt'n
Slow day Kiwi? That company was running out of cash in a hurry....... a reverse split is not happening with AMRN
Wow, things move pretty slowly over there in the Emerald Isle
Slow day at the Simply Wall Street office?
https://finance.yahoo.com/news/heres-why-were-not-concerned-110655793.html
Congrats Nukem........ your AZ boys put a hurtin on the lowly Lambs.
Thanks Dar.....
Did I imagine it or did one of our esteemed posters post something about if AMRN starts buying back stock that they can only buy back around 350K shares a day?
Well Kiwi, be skeptical when studies are referenced...... who benefits by a favorable study on a Trillion dollar drug? Who sponsored said studies? Follow the money!
Let me know what you think of this presentation.
mm, excellent questions that all of us would like the answers for.
Hi Rose...... would have been interesting to ask your new physician why he is on a statin? Also if he is aware of studies showing the negative effects of statins as it relates to increases in diabetes, dementia and alzheimers.
Well let's hope you turn out to be an AMRN millionaire
Have your friend compare the possible side effects between Jardiance and Vascepa and is there a reason that he/she couldn't take both?
Very.......I'm tempted to sell 1 share to send institutions into a buying frenzy.
Volume today could be lowest in recorded history
Kiwi, I'm all for you doing what makes sense for you. We all need to get as much information as possible and then take responsibility for our own health. Statins have their place but far too often they are recommended just because of an LDL calculation that is above the current standard for Normal. I'm the perfect example of someone with arguably an excellent lipid panel other than LDL being 200. It's 200 because of cutting out carbs. You would think that with all the attention paid to LDL that GP's, PA's, and Cardiologists would know more about this. Based on the important role LDL plays in the body, why would my Dr suggest I take a statin? Simple.....go with the flow and follow outdated group think. It would actually do more harm to me than good. Clearly I have trust issues. Does V help with that?
As I like to remind everyone.......LDL is the fireman not the arsonist. We need to fix people that are metabolically broken (fix what is damaging thier LDL particles) and get them to eat properly.. Great presentation and worth watching.... not too long.
Agree totally
While searching for some details on the Jelis study, I came upon this article
"A Critical Review of Icosapent Ethyl in Cardiovascular Risk Reduction"
with details on all the studies we are familiar with in a decent format. It may have been posted before so feel free to ignore it
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184960/
So you want to invest in a drug company?
https://www.yahoo.com/finance/news/analysis-us-still-pay-least-100704407.html
I prefer the buyback......... If the share price stays at this level, what good is it to us shareholders anyway? If we expect it rise, then I want as many shares as possible taken out of the float at .61
Zip, I would conclude that "maximally tolerated statin therapy" includes those that cannot tolerate statin therapy...... for them 0 is the maximum.
Cardiovascular risk reduction
Indicated as an adjunct to maximally tolerated statin therapy to reduce risk of myocardial infarction, stroke, coronary revascularization, and unstable angina requiring hospitalization in adults with elevated TG levels (≥150 mg/dL), AND
Established cardiovascular disease, OR
Diabetes mellitus and 2 or more additional risk factors for CV disease
Yikes Zip........ Are you taking a statin? Is your LDL "normal" because you are taking a statin or is it just regularly normal?
If people are going to continue to eat like crap and sit on their arses all the time, then I know a drug that can reduce your risk of this.....
https://www.yahoo.com/lifestyle/more-middle-aged-adults-dying-201053284.html
Pretty sad though that it is happening more and more in our younger population.