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Yes CT.gov does say estimated completion 9-30. But we just heard ,9-30 of 102 patients enrolled. Couple patients a day.?. Certainly not completed.
JJ 9-30 video caused discussions here and I'm still not sure. 30 days from 102 patient data review due early Nov for continuation.?. Is or will be used for EUA? Full enrollment then data review.?.
That's, us. Speculative stocks on the OTC are a ride. Bth and Nash were small potatoes compared to a possible COVID treatment contribution...JMHFO...
BTW no dramatics needed, just your opinions and noted research...GLTA/U...
If we get good data from the Covid trial it's been stated that the path is to sell their rights. A fairly low cost addition to Solutions for Covid conditions and after effects. Then going forward with CC/NASH/IBD/CKD. I'm PRETTY SURE EVERYONE wants to get PAID and will let this run into initial news. See the StreetSmart interview. Raising again at $5+ for other repurposed drugs, BFD...
COVID patient Enrollments are progressing quickly and CEO says completed soon, data by mid Dec.
A $1B or $2B goes a long way with 200M fully diluted. Yea, I'll take shares as a partnership...GLTA...
My bad, Aug was 88 enrolled and 102 announced 9-30, full enrollment in Nov.?. Discussions on this MB that day and since were DrJJ video vs pr. Some suggest data readout of the 102 in 18 days from now. 102 review is to continue trial.?. Maybe but CT.gov and Dr.JJ said q1 2021. Emergency Use A request is separate.?.
My point was the issues with long infusion courses and possibly taking a placebo,*. All while heavily backed Big-pharma Trials with easier courses are available. Some solutions in Trials are a pill.
An Inhaler / nebulize procedure is the gold ticket. Cant see politics (K street) letting the FDA give much now, IMO. Peer reviewed results minimum.
Not short but riding some frees. I doubt the big holders read my Ihub posts. I do follow your evaluations here and agree with some of your perspective and opinions...
*Faced similar.
Last news was 88 enrolled and expect 102 by Nov. Data Q1 2021.?.
The 3 days of 12 hour intravenous infusion is probably a little daunting for someone that may receive a placebo. Sure they want the drug not just a chance...
Seems like all these Influenza drugs approved by the FDA are using H1N1 as the worst case scenarios. Ifenprodil has shown a 40% or better results in their animal studies.
"Because currently circulating influenza A (H3N2) and 2009 H1N1 viruses are resistant to adamantanes,"
"Since the recent emergence of 2009 H1N1 virus, oseltamivir-resistant seasonal influenza A (H1N1) virus has been of less clinical concern because very few seasonal influenza A (H1N1) virus strains have been circulating (113). Nearly all sporadic cases of oseltamivir-resistant 2009 H1N1 virus infections identified to date also have been associated with the H275Y mutation in neuraminidase;
"The predominance of atypical presentations involving primarily dehydration, irritability or poor oral intake have been reported among some young children with 2009 H1N1 virus infection (77,78)."
https://www.cdc.gov/mmwr/preview/mmwrhtml/rr6001a1.htm
Aviptadil and some others, certainly don't have the past of Gilead/Rem, as it was developed in Wuhan during research. There is a direct path from there to the rest of the world. Bat soup?
While looking into Regn-cov2 I keep finding talk like this. No firm explanations with round-about denials of the use of aborted fetuses' stem cells.
We can guess that R-cov2 will be extremely more expensive than Rem. Both seem hard to manufacture with questionable ingredients. Both have ethics issues. Both have limited access and incomplete Trials... Dexa*.?.
Average Covid infected patients don't receive care as early as Mr. T did. Most would only get one experimental drug at a time. Most insurance companies balk at even ONE experimental drug and then patients need to have strong Doctor support to just JOIN a Trial, then submit to their Ins-co. All this takes TIME Covid patients can't waste.
Apparently the early attacking Covid is working better than reactionary Treatments...Just some opinions...
https://www.usatoday.com/story/news/factcheck/2020/10/08/fact-check-trumps-antibody-therapy-not-made-fetal-stem-cells/5901542002/
YES, The JCS is in Quarantine from being exposed to COVID along with much of the Whitehouse staff. CG JCS tested positive. YES that is a Big deal.
Super spreader events are usually due to the Lack of personal responsibility. JMHFO... Masks and distancing anyone?
I thing discussing the current administration's actions directly relate to stocks/this stock along with any directly related political actions is Important.
To?>
The excessive past posting by some for DT to try, publicize and pump RLF has triggered responses, too. Cant have it both ways. I guess some/* have moved to other pastures after excessive personal opinion and political postings here.?.
Great DD by some has yet not been 'stickied'. MY Thanks for the serious efforts by some...
Please, any Mods still here may consider editing the Intro, current developments and stickies. Deleting selected posts in a thread denies continuity of the discussions and equal Rights to opinions/conflicted opinions. Few enough posters left already.
aGuy, Volume continues to decrease putting pressure on any forecasts,?, IMO. Reactions to weekly/daily "news" (repeats) seems to also be a questionable influence. Thanks again, many appreciate your efforts...
Great work, Thankyou for the efforts...
Dumb to put it in the Monthly then close it days later. Should have just let it die quietly. Novotech owes AGN some big efforts somewhere or a pocket of cash back.
The cost for a course Ipillmumab/Navolumab is $450K for initial dose combo and $7K twice a month for just the lesser maintenance doses of Optivo. Medicine is Expen$ive and requires great insurance or ridiculous out of pocket. BUT, it's better than death. BUT2, customers have to be able to pay for it. Now what abouth ETHICS as Dr. JJ points out.?.
I think we could do better here with a target price for Aviptadil (IV) much less than is talked about. After manufacturing and logistics what is a reasonable price?
I read that India has a knockoff of Rem pretty cheap.
I hope the prototype Inhaler ,when seen, will be planned for MASS use, Cheap. $20-$50 a few dose unit? Selling a couple hundred Million of those (yearly?) is a better bet than targeting High-end Rich. This all needs to get thru trials, against Big P with their own obvious current support...GLTA...
We'll need some more serious volume for anything, IMO. Too many repeat pumps, inferred exaggerations, flippers, OS, IMHFO. DATA please.
Mr T's attempts to 'hand out' FDA status for his opinions of drugs is causing more doubt than support. Even E Lilly and Regn want confirmed data from Trials. He wont be handing out FDA support to anything but his buddies in BIG pharma. JMHFO...
BTW, Mr T states continued hate and blame at China, yet Trusts Rem which was developed/leaked in Wuhan Virologic Inst, CHINA...?...
I still see the South Korea Trial listed in the monthly. The two new site locations, Yonsie and Cung Agn are in Seoul, where there is a continued fight against local super-spreader issues. Still over 100 critically sick patients in Seoul hospitals, and still 100 new infections a day.
24000+ total now. Last I saw was about 14000. Sad we all thought that SK was a leading country in their 'successful' fight. They have absolute control of visitors/quarantine, excellent testing etc.
With SK still having some issues I wonder What is Really happening in China, no WHO there to report and our NIH monitors were kicked out/some were removed by Mr T...
BTW, tell Mr T that his 'miracle' drug Rem was developed with Gilead at Wuhan Virologic Inst, CHINA. With his hate and blame of China, why is he Trying, Trusting and Pumping Rem? It's barely statistically affective. He's so lucky and may not get really sick as he pumped all those drugs at the first sign / test of COVID. Most are forced to wait several days before serious treatments, even for testing's.
E.Lilly and Regn are cautious of their antibodies and want those Trials to be further completed before they apply for special FDA designations that Mr T just wants to hand out now. Mr T is still Contagious along with a good portion of his staff. The JCSs are in Quarantine.
BTW2, thats why we dont see Pince talking much, he even tried the Mr T rules of debating. Fact checks anyone? Masks?
...GLTA...
Free means taxpayers just like his visit to WR. Disgusting for the pump of drugs that are not tested. Mabs are expensive and dont work on all...JMHFO...
Street Smart also made these nice write ups too...GLTA...
https://www.streetwisereports.com/pub/co/9895
An Inhaler for prophylactic use is needed Now, at a fair accessible price. Pumping low success rate wannabee drugs for a few is less desirable or affective. All Americans should have the same accesses to SOC. New Treatments should be Judged equally in Clinical Trials. What if a vaccine or Treatment turns out harmful outside the Trial paths? What if it allows hidden Virus progressions or varieties. Mabs are defeating many Cancers so far but detectable levels are still present. Aids?
Most Americans and people around the World wear Facemasks and practice Social distancing. All Soldiers / Doctors / most citizens' workplaces are Required to follow these rules.
The JCS is in Quarantine because of casual attitudes of the few. Super spreaders have been and are the largest path of infections. Cant usually cure stupid, but I hear it is contagious...
https://www.nytimes.com/2020/10/06/us/politics/trump-coronavirus.html
Those receiving Care at A VA like WR DESERVE Exactly the same SOC and Drugs that Trump received at THEIR hospital. Why should Veterans receive something less or experimental until AFTER the Current Best Care is Given. These Men and Women are mostly Service Disabled. Sure they should be Allowed to chose care paths BUT should receive the BEST Care the USA can give. FIRST, Yes 10 Doctors each, Just like Tump. No guinie pig stuff... JMHFO...
I dont think any of those indications RA etc, are being goals in current Clinical trials with RLF.?. A VIP competitor is after those indications with Trials from what I read.
Insider info release will not be helpful. JMHFO, all these guys better use proper channels for info distribution. Every time a rumor fails to materialize stimulates flippers...
Good Presentation on the new forum. Dr KSS added some scientific color. Strong opinions during financial discussions with Licensing/partnership a target, not dilution. Could be finished with last dosing of COVID 150 patient Trial by Nov with data 4 weeks from that...GLTA...
https://www.chicagotribune.com/coronavirus/ct-nw-nyt-coronavirus-vaccine-guidelines-20201006-imticmubxramhl4nfw4zuhsdca-story.html
Of course DT was able to max dose several drugs at the beginning of his COVID case, maybe suppressing it but not COVID Free or non contagious. So many will certainly not receive that SOC. Now he's saying NBD about COVID.
No strategy developed in isolation of over the last many months. States fighting over resources, no National plans has exacerbated the situation.
Rehash of splitting the pies.
Only thing new I see for the 21 + 30 is "The results have been submitted to a peer-reviewed journal". I guess these will be published before the end of 2020. Production and logistics are being planned for Q1 2021.?...GLTA...
%17 were Not survivors? or just not released from care? I thought overall rates were<3% for COVID. Dont know what data you're looking at though.
OAN...
FDA looking at granted permissions, Rem low success higher risk, High cost in US/Japan/EU and Knockoffs in India @$<20?.
https://www.thailandmedical.news/news/breaking-covid-19-drugs-remdesivir-approved-by-trumps-administration-causes-serious-kidney-problems-eu-regulators-starts-safety-review
Showing the Flag as President was OK. He's sealed in that car section with separate O2. Anyway, I hope. Bless the USSS guys and gals...
Also I see DT as causing a super car accident, with 210K dead and countless wounded, by not following rules/driving on the wrong side at 100mph. We should be More worried about those than pampering the causer suffering for something he caused all to suffer.
What about the CARE for those at WRAH with True Service Connected issues.?.
My respect to him for 'Showing the Flag'.
I noticed the experimental treatments he has taken are from huge Pharmas. Someone posted the THAI medical site which seemed to have good collective info, one is about Rem, anti-*s, medical issue info/references.
https://www.thailandmedical.news/news/breaking-covid-19-drugs-remdesivir-approved-by-trumps-administration-causes-serious-kidney-problems-eu-regulators-starts-safety-review
I guess my points were skepticism and cost of antivirus - anti** - treatments. People that can get it want Rem even in spite that it's not dramatically effective and not cheap. Insurance Groups/Govs - patients get covered treatments and Hospitals can get paid. Hard to get medical infusions besides professionals/Nurses.
I would hope for "Inhaler" formulation mass targeting. Something like 'over the counter' at Wallgreens etc. Possible IMO due to good past safety records. With a large enough supply, "inexpensive to produce"... PRICED VERY REASONABLY... So that masses can access it's prophylactical effect and also use it as part of a treatment. (ie, asprin- blood pressure med).
Not many can access the level of treatments and 'Care' available to DT. 10 Dr's consulting each other just on camera and countless Support Workers, most taking risks.
Most don't have even 'Cadillac plans' and certainly Not access to that. Even Veterans in that Same Hospital are probably sacrificing...Anyway.
IE... a Buyout, YES Buyout. ASAP. JMHO...GLTA...
My opinion is that RLF is trying to set too high a price for a drug that will compete with Remedysevere's* exposure. Many will chose the semi proven/semi affective - publicized Rem. IMO. Most will never get mabs/antigens either, course price issues too.
With the low cost of manufacturing(?) Aviptadil, a serious look at pricing may be an answer to getting this drug out. Sure some logistics issues until something with the Inhaler is accomplished. Other competition may be as effective/much less expensive and all will have Trials to prove it.
No magic this late in the race, IMO. I dont think recruitment of DT or for Trials with the IV course is as accepted against current treatments or priced reasonably to get some attention.?. 3X Rem?.
Phobic DT and populace/insurance companies.?. Few want a vaccine yet, if/when.?.
Data from lackluster enrollments Q1 2021.?. Prophylactic use/Compassionate use/not easily administered IV course.?.
Very happy there is now a Site for Inhaler Trials to be registered.
Tif, excellent DD-COVID chart/map. My thanks. Seems to be lost in recent postings, repost may be in order.
*(Gilead-Rem/Wuhan China origins)Initial escape during research. batsoup??? I dont think so...
10 Doctors just at the WRH press conference. I hope Veterans with COVID in VA hospitals get something close to that care. POTUS self inflicted by not Masking. Pumping all kinds of expensive experimental stuff, hope others get access to that level of care but that is not logical. Ifenprodil is a comparatively inexpensive treatment for the Rest of Humanity. May be proven to be at least as affective. Looks like we will hear soon...GLTA...
gregjr, look for the +-.
Interesting COVID Map. Algernon is right of Map legend, follow path..
-> Prevent aspects of Cytokine -> Target aspects of Inflammation ->Aspects that Reducing Immune cell Trafficing -. NMDA Receptor Antagonist...
https://racap.com/media/Covid-19/COVID-19_TX_09302020_F.pdf?v=O7RntLhd29chARXm5ScrGTR3-P2jpMyn6M-RViFJeQA
AGN and all of us Wish All those suffering from COVID diseases our Best Hopes and support. Deepest Respect to All the workers in Healthcare Groups and the Military...TCM...
Sorry not new, at .Gov since April/June. Look at the Trial ID number... No location was posted at .Gov so confirmation of a Site real is important. Recruiting should be easier than the IV transfusions, (3X 12hr)...GLTA...
https://clinicaltrials.gov/ct2/results?cond=&term=aviptadil&cntry=&state=&city=&dist=
Its not a shot but a 3 day, 12 hr each, infusion series. I would guess he has a herd of doctors with Remdesever and Colonquin. (LOL). I doubt he will try any Trial drug, being he is a hypochondriac, but maybe.
Unfortunately for the USA there might be the whole supporting group of Staff, aids and some cabinet members infected, COVID is airborne. This could become a critical issue, Stupid not to follow Science and wear a mask, IMO.
Probably didnt get it from his wife as she wont even hold his hand, (Debate). Now 'mild symptoms' at a couple days, just detected even with the regular testing regimen. OMG ?
Senate GOP votes NO on COVID Bill just now and blocks aid for the rest of the USA.
In the PNW we see Flyways being ruined, mass dead birds, bees, insects past public access lands closed, see above issue.
Impractical for large scale, there was a company trying to sell clear pnls on huge windowed bldgs. xsnx. In appropriate areas solar charges fuel cells and boots Xmission lines, small community power. Silicon is dirty to make and supplies/access are limited along with sunlight.
We have Hydro here when there is normal rainfall.
Most places use Oil, NG/RNG, Nuclear and some coal. You plug into one of those at most places around the world for those that use EVs...
Yes after all bills, debt, loans and Change of Control payments, everyone gets shares as payment or your broker can take cash to your account.
JMO, experiences.
Riding free shares until something here changes. Buyer @<$.4, maybe...
I saw it in the "debate" when Biden got a sentence in about new and existing Generation facilities are being retrofitted and all new ones built to NG/RNG. Old news. How else does someone charge an electric vehicle? Show us an EV that does not 'plug- in' to an external power source or one where a battery can be 'changed out' quickly and not have recharge time. Solar pnl on the roof, LOL?
Biden is wanting to continue Power Plant RNG change over from bunker oils (etc) to NG/RNG and is for putting stations into new Infrastructure highways for reduced pollution there too.
ALL electric vehicles need charging, they cant carry enough solar pnls to charge themselves, so they Must plug into something and take the time to charge. Forklifts etc used to have swap out batteries to keep working while another was charging. Impractical for current EV car models. Forklifts for manufacturing and warehouses have mostly moved to NG/RNG also to avoid the dead battery pollution issue and recharging time/logistics.
Continued subsidizing of Oil and it's much worse pollutions has to change. The USA has one of the worlds' largest NG reserves and is working to build-out the RNG / methane sources to reduce that uncaptured pollution...JMO...GLTA...+
I like the large group of past Trials and especially the recent COVID/ARDS/15more indications, Phase 2 Trial with those good site locations.
Little or NO Fluff here, serious science with a strong History in this field. Hard to beat <15M float...GLTA...
https://clinicaltrials.gov/ct2/results?cond=&term=pb1046&cntry=&state=&city=&dist=
After the excessive pumps and failures with contradictions from Real medical people, Mr Tromp may not be the one to pump yet another drug. Other drugs are having successful enrollments/trials and some at a fraction of this one's OS. 'Only' and 'Cure' are opinions until proven at ClinicalTrials.Gov. Hype is not a treatment/cure.
Taking my ball to another court while the wait for data and enrollments continues and maybe be back @$?...GLTA...
Honor Veterans and Healthcare workers when possible.
Well, GEM and insiders have at least 1B shares and I guess they accept any liquidity. Got their past shares real cheap, just paid a fairer price for the recent ones. They interview maybe wasn't needed, IMO, BUT info/?...I also feel more selling in the near term, momo. Might buy some...GLTA...
Another COVID treatment I know of has just announced enrollments are going ahead of plans...GLTA