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Re: None

Monday, 10/12/2020 11:08:12 AM

Monday, October 12, 2020 11:08:12 AM

Post# of 16706
Seems like all these Influenza drugs approved by the FDA are using H1N1 as the worst case scenarios. Ifenprodil has shown a 40% or better results in their animal studies.

"Because currently circulating influenza A (H3N2) and 2009 H1N1 viruses are resistant to adamantanes,"

"Since the recent emergence of 2009 H1N1 virus, oseltamivir-resistant seasonal influenza A (H1N1) virus has been of less clinical concern because very few seasonal influenza A (H1N1) virus strains have been circulating (113). Nearly all sporadic cases of oseltamivir-resistant 2009 H1N1 virus infections identified to date also have been associated with the H275Y mutation in neuraminidase;


"The predominance of atypical presentations involving primarily dehydration, irritability or poor oral intake have been reported among some young children with 2009 H1N1 virus infection (77,78)."


https://www.cdc.gov/mmwr/preview/mmwrhtml/rr6001a1.htm