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Yes, the FDA will never care about all those dark green protestors citing "Monsanto" and "Agent orange" in front of their windows and will simply let the military do whatever they want, even relaxing their own approval standards for them. Highly unlikely. Even if the company has assets in Vietnam for all the countries in the world. That would never bring back inconvenient memories ever.
Actually insects have a vastly different anatomy than us, mammals. Fat body is the main organ of a larva ( https://en.wikipedia.org/wiki/Fat_body ), and usually the largest one. Actually silk worm fat bodies are 50% larger than their silk glands ( https://www.jstage.jst.go.jp/article/kontyushigen1930/58/3/58_3_221/_pdf ).
"Next, one has to separate the proteins from the silkworm. We don't have to do that with silk because the silk is extruded by the silkworm. No separation necessary. I don't have any idea how hard it would be to separate pharma proteins from the silkworm corpse, but this could be a challenge as well. "
Hard is just a question of cost. If you check out this post I made earlier ( https://investorshub.advfn.com/boards/read_msg.aspx?message_id=151161269 ), for instance monoclonal antibody purification costs 0.2 USD/mg. Which is totally prohibitive for silk, which sells for 0.00005 USD/mg, but negligible cost for antibodies which sell for 200 USD/mg. Again: Producing extremely valuable proteins in silk worms can be a huge business. Companies are not doing that because it is almost impossible to get the GMOs approved for molecular pharming.
"Finally, the proteins that the silkworm is producing and storing in its body fat must be compatible with silkworm growth and reproduction. Might the proteins be toxic to silkworms? "
Most likely some will be. Others not. Producing the ones compatible with silkworm metabolism would still be a huge business.
"
For all these reasons, I consider the possibility of drug production in silkworms to be more of an unproven possibility and less than a sure bet,"
For all these reasons I consider molecular pharming a pretty feasible way to grab some quick cash. Most likely they can produce antibodies, which have the largest market share as therapeutic agents. And they sell for a lot more than silk.
One of the main advantages of genetic engineering: You can export the GM-silkworms into Vietnam, produce them commercially without ever revealing anything on how they were mage. Yes, the construct can be reverse engineered from the moths genome, but that can be done anywhere. This industry is not like electronics, where the production line holds the key to manufacturing. moths can be reared without any knowledge on the engineering methods used on their distant ancestors.
"If you have any information on requirements of the FDA for GMO's that are not eaten, that would be helpful."
GM-cotton for instance. https://en.wikipedia.org/wiki/Bt_cotton
And GM-silkworms are regulated by the FDA:
https://www.loc.gov/law/help/restrictions-on-gmos/usa.php
"The FDA also asserts jurisdiction over genetically engineered animals, pursuant to its authority to regulate “new animal drugs” (NADs) under the FFDCA.[52] Under the FFDCA, NADs are deemed generally unsafe unless the FDA has approved a New Animal Drug Application (NADA) for the particular use of the drug.[53] Except in cases in which the FDA exercises discretion to decline to require compliance,[54] or where the drug is only for investigational use and thus need only conform to specified exemptions,[55] the FDA requires a genetically engineered (GE) animal to be the subject of an approved NADA based on a demonstration that it is safe and effective for its intended use.[56] A NADA for a GE animal must include information on the animal’s identification; chemistry; clinical purpose; labeling; components and composition; manufacturing methods, facilities, and controls; safety and effectiveness; environmental impact; and other information.[57]"
"Do you think they currently aren't producing GMO's in the U.S.? "
Yes, they are producing GM-silkworms. In limited quantities in research laboratories. Experimentally under umbrella licences research institutes or companies have on GMOs which are not sold on the market. And some GMOs are produced commercially with the approval of the FDA.
"They produced enough for the Army to send them shoot pack panels."
How much did they sell those panels? Experimental, scientific, research uses are widespread, but selling GMOs is a completely different matter. For our purely selfish reasons we are only interested in silk if it can be sold for money to generate revenue.
"Would this require approval?"
A much looser approval for research and development uses which can be obtained easily.
"Do you think they didn't have that approval, if required for non-edibles? "
Most likely the experimental rearing of silk moths was approved. The commercial production of them not.
"All GMO's on the list of approved GMO's are edibles. "
Actually there are several strains of alfalfa and cotton on the approved GMO list none of them edible. https://www.ncbi.nlm.nih.gov/pubmed/28230933
"If I remember correctly, KBLB has a statement from the FDA that says approval is not required."
Highly unlikely.
Let me tell you a story from the same source: https://www.ncbi.nlm.nih.gov/pubmed/28230933
"BOX 3-2 The ProdiGene Incident: Noncompliance with Regulatory Processes
The production of plant-based pharmaceutical or industrial proteins has two main components: the GE
crop and the bioprocess to achieve the final product. ProdiGene was a private biotechnology company
based in College Station, Texas, that focused on the use of GE plants to produce proteins, enzymes, and
molecules for pharmaceutical and industrial applications. In 1997, ProdiGene began field trials for GE
maize plants in Nebraska, Texas, and Iowa. The company’s largest trial was conducted in 2001 to produce
a combination of proteins in about 22 hectares of maize. 1
In mid-2002, the company entered into an agreement with Sigma-Aldrich Fine Chemicals to
manufacture recombinant trypsin using ProdiGene’s GE plant system. The GE maize expressed trypsin
genes from domestic cow in the grain (USDA-APHIS, 2004). The process promised to be scalable and
profitable for both sides because of a high demand for animal-free products; traditional commercial
production of trypsin involves animal systems (Wood, 2002). However, during field trials of commercial
production of recombinant proteins in GE plants (maize), the company was faced with a series of
noncompliance events that led to punitive action.
In September 2002, inspectors from the U.S. Department of Agriculture (USDA) found volunteer 2
maize growing in an Iowa soybean field that had been a field-test site for ProdiGene’s GE maize during the
previous growing season. ProdiGene failed to notify USDA, in accordance with permit conditions, about
volunteer maize plants with tassels within 24 hours of their discovery. After the discovery by the
inspectors, ProdiGene destroyed some 61 hectares of maize seed and plant material within 400 meters of
the previous year’s test plot under the inspectors’ supervision.
In October 2002, USDA inspectors again found volunteer GE maize with tassels from the previous
year’s Nebraska test sites growing in a soybean field. The company was ordered to remove all the volunteer
maize to prevent its harvesting with the soybeans. However, the company failed to remove the volunteer
maize, and about 500 bushels of soybeans were harvested and sent to a grain elevator, where they were
mixed with another 500,000 bushels of soybeans. At that point, all soybean movement at the elevator was
stopped, and USDA destroyed all 500,000 bushels of soybeans.
After an investigation by USDA’s Investigative and Enforcement Services and a formal administrative
proceeding, ProdiGene was issued a $250,000 penalty. In an additional consent decision, ProdiGene agreed
to reimburse USDA for the cost of buying, moving, and incinerating 500,000 bushels of soybeans and to
post a $1 million bond to demonstrate financial responsibility for any future violations. USDA provided an
interest-free loan to ProdiGene for the full $3.75 million penalty and clean-up cost. When International
Oilseed Distributors, Inc. bought ProdiGene in August 2003, it assumed the unpaid portions of the USDA
loan.
In 2004, a USDA inspector found volunteer maize in baled oats that had been grown in the fallow zone
alongside a ProdiGene test field that contained a maize variety engineered to produce pharmaceutical or
industrial compounds. The baled oats were to be used as on-farm animal feed. The inspector found
volunteer maize growing and flowering in the fallow zone surrounding the test field and in a nearby
sorghum (Sorghum bicolor) field planted within a 1.6-km isolation distance. As part of its remedial action,
ProdiGene destroyed all volunteers in the isolation zone and plowed under the sorghum field under USDA
supervision; all suspect oat bales were quarantined and later destroyed.
In a July 26, 2007, settlement with USDA, ProdiGene, Inc. paid a $3,500 civil penalty and agreed that
neither it nor “its successors in interest” would ever again apply to USDA for a notification or permit to
introduce GE products."
Bacteria do not make secondary modifications, and yeasts usually over-glycosilate proteins. That's one of the reasons, why large proteins for instance antibodies are produced in mammalian cell lines.
Yet I agree, a rice or corn based expression system would be much more efficient, but to approve those 10+ years would be needed. And it seems that Kraig Biocraft has some kind of umbrella approval for GM-silk moths in Vietnam. As inefficient as this may seem, from a regulatory standpoint it is a gold mine, the only possible molecular pharming platform on Earth that has been approved.
Actually GMOs in the US are approved by the FDA. Can you show me a single instance, where the military forced the approval of a GMO? No, because it never happened. So speculating on the army sidestepping the approval process is in the land of fantasy. Not impossible technically, but not too likely to happen.
That was my original post: Silk has some constraints, but a silk worm is still an animal, a lot of proteins could be produced in it if not for the silk fixation of the company. To produce a protein and let it accumulate in the fat body, as I originally suggested is not hard at all. And silk genes could be left alone.
Alternatively a nice cost cutting measure would be to make silkworms that spin spider silk and produce a recombinant protein too. That way the silk from the cocoons and the pupae themselves could be used.
I have read the press release but have mixed feelings about it.
First the US production. This is insane. GMO regulation in the US is still prohibitive, getting a single GM-silkworm approved will take 100+ million USD and 10+ years. Talking about US production means sometime in the mid-2030's. This is useless and pretty much scary. They spent a decade finding a country where the government will allow them to rear GM-silkworms and then start a multi-decade long journey again to go back to the US? Not mentioning that apparently in Vietnam they can switch to new silkworm strains without additional approval, while in the US they would need to re-approve every single new strain, taking decades.
This is just simply stupid, and means that commercialisation of this technology (=revenue) will not happen in the foreseeable future.
The other main point is much more interesting. Apparently they can produce pure spider silk now in silk moths. Which is fine and all, but this particular application works only with proteins that can be woven into a thread. This can be a huge advantage if they can produce the silk proteins they promised, this can be a tremendous achievement.
However they never talk about the company's greatest asset, it looks like they are not aware they possess it at all. Apparently they have some kind of umbrella approval to produce whatever strain of GM-silk moth they want in Vietnam. This is something a ot of big companies desire, but none other have. Why do they not try some molecular pharming? Producing recombinant proteins is a huge business, just inserting a gene into the silk worm genome to produce any protein in the fat body would be a no-brainer cash grab. Easy to do, fast to accomplish and could generate revenue immediately. Why does the company not do this? They would only need to partner with other companies and produce antibodies, enzymes, whatever they need. this way they could outgrow the silk market without effort.
TL, DR: The US production is bad news, the pure silk is fantastic and some huge opportunities are missed by this company.
It would be a funny outcome if in 2029 both KBLB and Spiber would be insanely profitable and market leaders in their own right just not on the same market. And yet we were speculating about competition, where none existed in the first place.
Agree completely, in any applications where strands of silk is needed the worm-spun threads are the most cost-effective solution and presents a far superior product. All the applications where threads are needed, the Moon Parka for instance are laughably unusable. And the cost of protein purification must be astronomical, it is hard to imagine even a cost-effective bulletproof west not just a t-shirt. That's why i bought shares in KBLB.
However in the direction where Spiber is going, for instance the silk coating of medical devices, the vat-grown silk seems to be superior. Protein purification costs a lot, but medical devices are already as expensive as they get and not a lot of silk is needed. However worm-spun silk contains a horde of other molecules (other proteins, chitin, etc.) which makes it totally unsuitable for this kind of raw usage. And if you need to purify and reconstitute the silk, then it is entirely possible that the yeast produced silk is cheaper.
I am just saying that as the anti-GMO useful idiots protected Monsanto's business for decades by purging every other company from the market, it can be expected that it will be much harder to enter the worm-spun spider silk market than the fermented silk market. In China, the most likely candidate where unlicensed silk operations could take place (and capture KBLB's profit) the complete GMO ban will hinder any kind of operations like this. And the situation will likely not change in ~5 years.
I agree. However this might be the key to Kraig Biocraft's success. Its competitors are frequently mentioned here in the forum, but Spiber and the others have the advantage that they use recombinant microbes raised in fermentors to produce the silk protein. It is much faster, you can get these fermentors and the transgenic yeasts and bacteria approved almost immediately. Depending on the country you can even get an umbrella licence where you only need to get the facility approved and can ferment any kind of microbe you please.
All the while KBLB's silk worms are considered GMOs, it takes years to get them approved, for instance the Aquadvantage salmon spent 23 years in approval phase. However this might turn out to be a hidden advantage: Any company wanting to replicate the technology will need to go through the same process. It took approximately five years to get approval in Vietnam, that means KBLB will have no competition for five whole years once it starts producing.
However Spiber and an other competitor will experience a curious phenomenon: During the years anti-GMO activists managed to completely disrupt biotech patents. Right now a patent only protects the exact DNA sequence listed in the application. You can create a "new" one which differs in a single nucleotide, but encodes the same polypeptide and you can manufacture it anywhere, as patents are easily circumvented.
So a successful KBLB will have no competition for years, while a successful Spiber's alternative manufacturers will spring up overnight.
Actually GMOs are fairly old. The first microprocessor was created in 1970, the first GMO in 1973.
How?
But okay, let's suppose a moth population becomes more resistant to parasites. And?
Then in that population there will be a few individuals producing stronger silk. Which does not give them any kind of advantage at all.
Actually you can not exclude the possibility that some would reproduce. Most likely a few individuals, but still.
Nothing. They produce stronger silk, which is completely unnecessary in the wild. They would reproduce for a time but eventually become extinct.
Possible that I only dreamed it.
I read it in one of the reports from the shareholder meeting. I tried to searh for it on this forum but could not find it.
Actually he said he will do the exact same thing at the shareholder's meeting.
He stated that stock price will increase and he mentioned a secret "long shot" that might increase share price to the point where a reverse stock split will not be needed at all. However he refused to elaborate this long shot.
Most likely we are seeing the long shot as it is unfolding.
For the second night they removed the Spydasilk logo. Is it possible that the show was done on Friday and that's it for spider silk clothes?
https://www.facebook.com/suki.suthinee/videos/10157755020359703/
Most likely we have a strong bias towards early PR -s. Simply because we do not want to spend the weekend in this limbo.
Thanks!
Actually the more I think about it, the more I am convinced, that fermented spider silk will evolve into a completely different industry, not a competitor for GM-spider silk. Those medical uses that have been proposed lately seem to be more suitable for fermented and highly purified silk proteins than worm-spun threads.
Honestly, I agree with you. If I would do it, I would spread the news. It is totally stupid to not follow this exposure with any kind of media presence. At least get the directors on stage and shhake hands with the M guy!
They are using a completely different approach. Both Amsilk and Spiber are producing silk proteins in microbes, purify and spin the silk themselves using machinery. This is their main advantage, as fermentation can be approved in weeks, it is fast and cheap. And this is their main disadvantage, protein purification is expensive.
I do not understand this myself. The Podium Lounge started at the same time as trading in the US on Friday. It would have been a nice day to officially announce the spider silk collection. Yet they only published an announcement about the new director.
But to be fair, they are not selling this collection at the lounge. They will sell it, if it is a commercial endeavour at all, not just some concept line (I am starting to doubt it, as they have shown several items already, too many for a simple concept). But sells will start from Monday, the Lounge itself is the advertisement. And as far as I can tell, these clothes can be available in extremely limited amounts from Monday. This way as you presume, ads come first and the commercial run right after them.
Ads are a bit tricky here, as I can gather this M guy is not selling T-shirts by the millions, but custom tailored clothes, basically he is an old-fashioned tailor for rich guys. HIs webshop is empty, I am pretty sure he does not generate his revenue from two scarfs a single shirt and a single gold medal he is selling there. Maybe his business model incorporates exclusivity, with selling products to clients personally. "This wonderful new fabric just for you, just now." And considering the limited amounts of spider silk Kraig Biocraft has produced, any large-scale ad campaigns would be a waste of money, they do not have enough product volume to satisfy millions of customers. But it might be enough for a few hundred shirts.
M is not advertising anything. On his facebook page, webpage, webshop, whatever he never ever disclosed that he is selling spider silk. The only mentions seem to be slips, mistakes and a sneak peek in a single fashion magazine. Honestly what will be over on Monday? Podium Lounge is an afterparty for Formula 1 crews and some rich playboys in Singapore. No clothes are sold there, not a lot of people go there in the first place, at most they will get a few nice shots out of it. Shots of spider silk products, yes real products on a real catwalk, real women wearing them, not a Moon Parka locked inside a glass cage.
And I suspect that this is a pretty brilliant strategy: If I want to put my product out into the world, but do not have massive amounts, I can not make a deal with Tesco to sell my clothes. But a small tailor shop with proportionally huge exposure is a nice middle ground: Low volumes of silk will be on the market for a long time, this M guy will not sell millions of shirts in the near future, a few kilograms of silk will last months. And all this time you can point to him that yes, my product is on the market, I actually have seen people buying it for real money. Yes, it is only sold in a small shop in very limited quantities, but I am selling it, generating revenue, and putting spider silk into the common consciousness of humanity. When mass production will be achieved I am pretty sure they will not try to sell tens of tonnes of silk through M the movement.
As I gather it, Spiber is out of the clothing business. They are focusing on this silk coating for medical devices. Which is a sane decision, no competitors on that market (silk produced in silk worms will not be suitable for this) and medical devices can incorporate exorbitant prices. Protein purification is expensive, as I have explained, but a well established science. If you can pay the 0.2 USD per milligram silk for purification and do not need threads woven, E. coli or yeast fermented silk is a much-much more viable choice than silk worms.
But I agree, Amsilk or Spiber can both be behind this show. I was convinced after Kenneth Le shared the Podium lounge ad, as he had no way of knowing about the totally secret show of a different company. And even if he did, most likely he would not advertise it. So I highly doubt it, and I actually forked out my own money to bet on this theory, so I think it is pretty sure. But I agree, I can be wrong. This still does not explain why Amsilk or Spiber are not advertising the show.
Where do you see this "everyone" who are promoting this event? A quick google search does not reveal a large media coverage. A ticket costs 188 USD, it is a cheap party with low-tier celebrities (Mel C was a star when I went to secondary school). To be fair we would have never ever heard about it if not for our investment in KBLB. NOt a huge twitter show we are being left out of. Most likely the KBLB announcement on Monday will gather much more media attention than the party itself.
Which can be part of the explanation: It does not matter whether they announce it on Friday or Monday, no one cares about Podium Lounge. Most of the investors, customers, etc. will hear about this only when some kind of press coverage will start. The question is, how much press coverage they can muster? If they can achieve anything like the Séralini study's media frenzy in 2012 and go viral within hours, then by Friday billions will have heard about the company and stock prices will increase above 10 USD. If they are executing this kind of a plan, they will need the media attention, then workdays are more suitable for this.
And it would be completely unsuitable to attack you for this question. Investing without asking these questions is a sure way to go bankrupt within months. I have heard about this fashion show months ago but did not even consider buying this stock until it was made semi-official by Kenneth Le's Facebook posts.
tl, dr: It is a possibility. It is important to ask these questions. We will only know for certain when press coverage of the event will start. This is one of the risks of stock trading.
I have not seen their contract. It is entirely possible, that this is some kind of deal between them.
But actually there is no coverage on the Podium lounge event itself. No photos on their website, not news items, if you google it, you can find a dozen photos on twitter and that's it.
Somehow this whole event is not marketed at all, no announcements, no feedback, nothing. You can only find last year's photos.
M did not post a single photo on his own facebook page. He clearly does not want to market the product just now.
My guess is, they want to make the announcement on Monday, 7 AM, to have the most impact on share price.
The stock exchanges will open on Monday. It makes sense to announce it two hours before trading starts, just to make the most impact. Otherwise announcing it on Friday will make it old news by Monday.
So it actually makes sense to announce it two days later, when it impacts the stock price the most.
You are preaching to the chore. I am fully pro-GMO and do not see any problems with KBLB's silk. However I am a small minority in the EU a pretty important market for silk products.
"And what would the "greenpeace" type have as a viable replacement?"
They do not have to offer any replacement technology. Just organise protests and bitch about these things. Greeenpeace is a propaganda organisation they do not produce anything, they do not research anything, just parrot the age-old anti-GMO lies and that's it.
"If Kim and crew were smart, and I believe they are, they would use that publicity to educate the public as to why spider silk is vastly superior to anything else out there."
Educate the public? Have you ever tried to debate an anti-GMO fanatic? They should pay Sporty Spice to wear a spider silk dress, it would be much more effective than any kind of education.
Here in Hungary people bitch about GM-canola oil. Which does not live, can not reproduce and basically does not contain DNA. The same with ground soy flour and processed GM-foodstuff.
Insanity does not need logical arguments.
"There are regulations on the growing but as far as I can tell once its harvested it cotton like any other cotton and not regulated any different "
Yet GM-spider silk is different, you can measure its tensile strength and identify the GM-silk in seconds. That's why IMHO first it needs to be a highly expensive status symbol, then it will circumvent regulations. After a year mass production can start by that time it will not matter at all.
In my experience that does not matter. The anti-GMO sentiment is the one factor common in the left and the right. For instance in the EU ~70% of the population is against GMOs.
That situation would quickly change after a few photos of Sporty Spice looking absolutely fabulous in a custom-made spider silk dress.
"They'll talk about how it's so good for the economy and that it's actually the vegan thing to do. "
Just observe how soy became a pariah crop from the absolute poster child of veganism in 20 years just because most soy corps are GMOs! Or how they oppose GoldenRice, even if this ban takes ~300.000 lives a year.
I have been lurking on this forum for a long time now and have been following kraig Biocraft since 2012. I originally became aware of this company through my popular science activity. I am writing a blog in Hungarian mostly about GMOs.
And I have noticed something that is rarely mentioned on this sub and usually left out of every calculation: These silkworms are considered GMOs and their silk is a GM-product. Most countries on Earth will require some kind of authorisation to even be able to import and sell them. Honestly, i have no idea what kind of legalisation applies to silk from GM-silkworms, but I would be surprised if these fabrics could be exported to the EU for instance without any kind of legal hassle.
I am pretty sure, none of us wants some Greenpeace assholes burning tons of silk just because their religion, and get Kraig Biocraft a reputation similar to Monsanto's. And if you study the history of GMOs in general, it is the absolute worst idea to dump GMOs into stores and let ordinary people buy them. Within days dark greens will organise protests and will ban the product from the majority of countries.
However this approach by Kraig Biocraft seems innovative and totally different from the old one. First just show the product as a concept. A few killer clothes, make them desirable but not threatening, it will take a long time to ship them to any store near you. Then sell them at an exorbitant price, that only the richest can afford. If I were the CEO, I would send a complimentary gift to every celebrity and politician in the EU. Make spider silk a highly sought after item that only the richest can afford and enjoy. And then start to sell bulk quantities, when people have been accustomed to the idea of wearing spider silk.
So most likely a slow start would be highly desirable in this situation. Not threaten the population, clearly mark it with trademarks, so no one would feel he is pressured into buying GM-silk. This collaboration with this M guy is the perfect path IMHO: Make it accessible but highly exclusive! In six months everyone will want a spider silk shirt (and no one will ask questions about GMOs), the company just needs to take a gentler approach.
So I highly support these kind of gigs.
Might be a little selfish, but what this company lacks the most is public awareness. I work at a biotech factory. A 100+ people work there all have at least an MSc in biology or chemistry, some even bioengineers, and whatnot. Can you guess how many of them have ever heard of Kraig Biocraft and spider silk at all? Yes, you are right, zero.
A fashion show might be the perfect thing to show that the product and the company in fact exists and draw some media attention (=investors) to this company.
Honestly spider silk woven into proper threads by a silkworm is a revolutionary material. Apart from a few artefacts nothing like this was ever produced on Earth before. DS 2.0 even exceeds spider silk, it is a completely new biomaterial. Even a few kilograms would be a huge PR gain: You can show them on videos, get the public to feel and accept the new material. And it would keep attention on the company until large scale production can start.
Honestly, did anyone ever seriously consider the possible uses for spider silk before? Clothes are fine. But a single bulletproof west does not require a lot of material (not tonnes) and it would make a killing PR to get a guy in a silk west, shoot at him, and show how he takes the bullets smiling (and without getting hurt).
At this stage it would be a very positive sign to show that the new factory produces silk even in kilograms not tonnes.
I am mighty suspicious about that claim. It is pretty hard to understand why the army would do anything like that.
Might be some kind of mixup, but the whole army is designed to avoid these kinds of mistakes. Still theoretically possible that the contact man left and there is no one to take his place just very unlikely.
Honestly, a few kilograms of spider silk is a very promising start. This company was unable to produce shot packs for the military before, it would be a huge improvement to see any meaningful amount of spider silk produced.
Actually Kenneth Le shared the Podium Lounge ad twice on his Facebook account. If any of the competitors supplies M, then Kenneth Le would have no way of knowing about it in advance and would never promote it himself.
Anyone knows where to follow the Podium lounge?
I might sound silly, but when will we know anything about that fashion show in Singapore? Is it broadcasted anywhere? Any blogs covering it? How will we know when the fashion part starts?
This story is the same with every company selling GMOs. Aquabounty took more than 20 years to finally be able to sell its product. Okanagana Special fruits spent 19 years until they got FDA approval on their product.
Kraig Biocraft had the same problem: It took a decade to finally find a country on Earth that let them grow the silkworms. Otherwise it would have been a much shorter process.