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Whale,
Are you sure you have your EPA/AA fraction right side up?
EPA/AA means EPA over AA, or a fraction with a numerator(top number) EPA over the denominator(bottom number) AA.
So if you increase the top number EPA while keeping the bottom number the same, the resulting number will increase. Increasing your EPA, will result in a higher number, which is opposite of your little chart.
For example EPA is 4 and your AA is 2, result will be 2. If you increase your EPA level to 6 and the AA stays at 2, the result will be 3, and so on.
Also, if EPA goes up, and AA goes down, your resulting number will get larger.
Please correct me if I'm mistaken.
Dave
Zip, Kiwi, Speaking of eyes, mine are 83 years old. I've been on V fo 10 years for CVD and Type II. Annual diabetic eye exams have shown nothing abnormal. And for decades I would get a stronger eyesight correction every year. But 4 years ago my eyesight stopped declining. Same glasses 20-20. I attribute all good heath issues these days to Vascepa. Dave
Nuke,
Great Timing. Here's hoping your sister-in-law responds well to the treatment, and gives that article to her oncologist.
Dave
Sorry, will try the link again.
Dave
EPA and Cervical Squamous Cell Cancer Study. EPA and The Prognosis and Response to Chemoradiotherapy. An initial report on a small study out of China. (The Title of the report mentions Omega-3, but the report itself focuses on EPA)
Med Terms: OS is Overall Survival; PFS is Progression Free Survival
Dave
jfmcrr,
Thank you for another great report on Vascepa. The best thing about Amarin will never be the stock price, it will be the health benefit that Vascepa brings to us. Keep up the good work. All the best.
Dave
Orbapu,
Wow, what a great outcome. Thanks so much for sharing. How can anyone with heart blockages and/or stents not press for Vascepa? Case studies like this need to be made known to the public. All the best to your brother and you. Dave
Orbapu,How did your brother make out on Vascepa through all that? I have a friend who recently went thru the same, and I'd like to forward any good outcomes your brother had. Thanks
Dave
Kiwi,
You mentioned the case where "their Cardiologists did not prescribe Vascepa because they were on blood thinners ".
So do they recognize that Vascepa has blood thinning properties? If so, now the Cardios need to learn that Vascepa is a Blood Thinner-plus-plus-plus etc. A much better choice.
Dave
Kiwi, I did not have stents in spite of 3 blockages in the 65-70 percent range plus Type II. In 1972, Cardio said my blockages were at the borderline and he was willing for me to go with Crestor(later Pitavastatin) , diet, exercise, no blood thinner.
A month later in dicussion with my GP, I mentioned I was eating a can of sardines every day for lunch, just because I thought it would be good for my heart. He said, "let me give you something to take so that you don't have to smell those sardines every day." And he prescribed Vascepa. (I've often wondered if an Amarin Rep had just left his office before my appointment-I doubt he was prescribing from data, just "no smell")
Dave
Kiwi, Excellent Proposal and Instruction on Power/Significance.
Along the same lines, do you think there are enough of us who have been on Vascepa for 5 years or more( typically after some intervention or detection), that could form the basis for a "post analysis" of subsequent "heart events," "plaque change," or similar markers? And I suppose a comparative non-Vascepa group could be identified easily.
As an example, I have been on V for 10 years after a CT scan and Heart Catheterization showed 3 serious blockages. As a researcher, I have always been hoping for a followup Heart Cath to see what if anything has changed. But cardios don't do a followup Heart Cath unless you present symptoms. Seems that individuals in my situation would yield some valuable data for just the cost of a 2nd Heart Cath. And of course others like me who ended up with stents, would seem to be an even larger group of candidates.
Thoughts, Ideas?
Dave
Capt,
Amarin should give you a commission. Great work!
Dave
JRoon,
Suppose Hikma had the correct indication on the Label, Trigs only, and a doctor prescibed generic V to a CVD patient.
If the patient then had a heart attack, wouldn't the doctor be liable for malpractice? Would this fear keep the docs precribing V?
Dave
Capt,
Regarding the Calcification score, Vascepa did not REDUCE Calcification over 18 months. But if the Placebo increased by 15 per cent, can't we say that Vascepa kept Calcification from getting worse? And I wonder if they are following the data past 18 months, as we've seen a divergence in Vascepa Benefit over time in other studies?
Not a Med pro but will relate my similar experience. At 72, a heart Cath showed me with 3 arteries blocked at 65/70 percent, plus Type II diabetes. The Cardio and I decided on the "medicine approach." He gave me a statin and my GP gave me Vascepa on a "whim."
I am now 83, no heart issues for 11 years. I walk a mile or two, 4 days a week.
Ask the doc who prescribed the "medicine approach" to include Vascepa. Doc should work with you. I've noticed that when you reach 80, the docs seem to be less restrictive with their prescriptions-they can always blame your demise on your old age.
Another Home Experiment with Vascepa: You may be aware that Vascepa will eat a hole through a styrofoam cup. So I wanted to see what it would do on Seborrheic keratosis (a harmless and common skin growth that is rough, raised and wart-like)
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I've been putting a few drops on my SK, once a day for about 10 days, and the height of it is receding, almost down to just skin. I'm wondering whether the SK lesion, is of similar composition to the plaque in my arteries? And is this little experiment indicative of the action of V on plaque? Dave
Two great V success stories from Ziploc and Tiger.
Send them to Amarin. Great stuff for advertising.
Send to friends with heart issues for use with their doctors
Thanks for posting.
Dave
Monk,
Thanks. I am Medicare Primary. My Secondary is the New York State Empire plan which includes my drug coverage managed by CVS something. And CVS has Vascepa in the most expensive of their 3 categories of cost.
BB,
I still pay $120 for 90 days of Vascepa in US.. When you mention the US "plunge in pricing this year," does anyone know the percentage breakdown between US Vascepa scripts filled at $120, and those filled at "plunge" prices? How many others are like me, and would that affect Amarin's US profits? Dave
Stock,
Isn't that decimal point between the 6's of Profit, supposed to be a comma?
dave
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goodwhale
North, mine is $120 for the same amount of V as you get for $15. I am also with CVS/Caremark under the Empire Plan of New York State, but I get the Rx filled at a Walgreens. So I hope Amarin is getting the benefit of the markup, and not either Pharmacy. And I wonder, if two pharmacies are involved, does that complicate the issues both in getting Vascepa, and the pricing?
Getting V rather than generic was no problem once I explained to my doc that generic didn't have an indication for CVD. I think any doc would by very aware of possible legalities if he/she were to refuse V, and I had a heart attack with my request for V on the record. Dave
Price Drop? Just picked up 90 day supply (360 Caps) of Vascepa and it was 7 dollars.
For many years it had been abt 110 dollars. Just wondering if it is a price drop, or some
adjustment the insurance company made. I am a New York State employee retiree covered by their primary insurance for all their employees and retirees. On the info insert it says that if I went to a generic, it would be 5 dollars. Is this what others pay for V? I'm hoping it was not a one time fluke! Dave
Capt: Is that ESC-2023 ad lacking the most important fact about Vascepa, The PERCENTAGE of RISK REDUCTION by adding it to a statin. Or am I missing something? I see the words "the proven efficacy of VASCEPA/VAZKEPA in cardiovascular risk reduction," but nowhere do I see the NUMBER, 25 or 30 percent risk reduction OVER a statin.. I keep harping on this because that has to be the single most important fact that practitioners and patients need to be informed about. It should be "front and center" on every ad and publication of Amarin.
Tatsu, How about some advertising that links V to statin users: EX " Double your Statins benefit by adding Vascepa" " Super-charge your Statin" "Double your Heart's protection, add Vascepa to your Statin." Throw in the Reduce-It numbers. You get the idea. Dave
Dukes,
A few questions about the case of FHEP not covering Vascepa. Is FHEP liable if one of their patients on gV has a cardiac event? Could FHEP avoid liability by saying that gV was equivalent to V? Wouldn't the FDA CVD Indication for V supercede any "equivalence" argument by FHEP? Wouldn't the "liability issue" be a better point of attack than the "infringement issue?" Dave
Mark, Rose, Walgreens new approach?
I take Vascepa, Statin, and 2 other unrelated meds. I just refilled the other two meds at Walgreens(Not Vascepa), and on the stapled info sheet for each of them, it has *brand name Vascepa* entered after my street address. (I had previously asked my doc for brand name telling him that generics did not have an Indication for CVD). I find it humorous that Walgreen's computer system must not have a place to enter an order for "brand name" so they tack it on to a person's street address! But maybe this is the beginning of an attempt by Walgreens to address the legal issue of generics stealing Indications from brand names.
It will certainly alert everyone in the pharmacy about my "special needs," and hopefully make them more aware of EPA's Indications. Dave
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Mark, Rose, Walgreens new approach?
I take Vascepa, Statin, and 2 other unrelated meds. I just refilled the other two meds at Walgreens(Not Vascepa), and on the stapled info sheet for each of them, it has *brand name Vascepa* entered after my street address. (I had previously asked my doc for brand name telling him that generics did not have an Indication for CVD). I find it humorous that Walgreen's computer system must not have a place to enter an order for "brand name" so they tack it on to a person's street address! But maybe this is the beginning of an attempt by Walgreens to address the legal issue of generics stealing Indications from brand names.
It will certainly alert everyone in the pharmacy about my "special needs," and hopefully make them more aware of EPA's Indications. Dave
Capt,
You did a good thing by going to IR. It can also be done, one doctor at a time like this:
I also agreed to a one month of Dr Reddy's after 9 years on Vascepa. It was due to my doctor's mistake in prescribing. When the refill came due I messaged the doctor that I preferred the real Vascepa because it was approved for CVD and Reddy's was not. No questions asked by the doctor and I was switched back to Vascepa. Think of the doctor's potential liability if I had stayed on Reddy's and for whatever reason had a CVD episode, with my request on the record.
It seems that any "thinking doc" would be quick to accommodate the patient under these circumstances.
Dave
Pdude: Question about your quote:
"The insurance company decides what the Pt gets and they ONLY care about price."
My pharmacy carries V and gv. I told my doc I wanted V and I would pay the extra cost. So I got V.
Are you talking about some other decision point in the process?
Dave
RMB,
Yep, each of us will die no matter how much Vascepa we take.
Dave
Pharmacy Dude,
Yes, this is that 2 or 3 page thing that the pharmacy staples to your bag with Hickma's generic icosapent ethyl. Who wrote it, or, where it came from, I have no idea. But it surely deceives a patient by claiming Amarin's Indication for CVD.
Dave
Meowza,
I can keep my Type II about 6.7 by restricting calories to about 1800 daily with occasional slip-ups. Metformin never seemed to do anything when I was taking it.
Dave
My Vascepa Research Study of One,
In 2012 diagnosed with 2 blockages in left descending arteries via catheterization, one 65% blocked, one 75%blocked, also type II diabetes.
Cardio said I could try diet and losing weight which I did and lost 30 ponds.
For 10 years low dose statin and vascepa, kept ldl in 70-80 range. Never had any angina or cardio episodes
In 2022 a new cardio tested me again with a nuclear stress test and I think echo imaging.
He said I had one blockage of 50 percent.
I don't know how accurate the second imaging was, but I'll take it.
I'm 82 now. Usually brisk walk 1-2 miles each day.
Dave
Capt, But if LDL-c is not a predictor of cardiac events, is your rise in LDL-c significant? Also, is Vascepa "super charging" statins, OR, is it ADDING prevention via the anti-Inflammatory affect, or some other unknown effect? Dave
Ram, Your CONFIRM-IT study suggestion I like. Are there enough Board members who have been taking Vascepa for say 5 years? And what are their anecdotal results regarding Cardiac episodes. Would they be willing to share? And would we get representation from those for whom V did not work? Any other possible reasons for doing it or not?
Dave