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Oh schiiet what a bunch of NONSENSE!!
No volume down here!
PAY UP!!!
Let`s ask it this way, do price move precede price appreciating moves?
Let`s say you see the price move on no news, do you expect news to follow or you never do?
Because that is how a lot of people got caught riding motorcycles.
He was holding, others were riding motorcycles.....
A case of calling the pot calling the kettle black.
LOL
Then I stand corrected.
I was talking about AD which would make the PD trial temporarily irrelevant.
It is obvious from the Australian news there is going to be a PD p3 trial.
To be fair PDD didnt claim to have met all endpoints, and AVATAR was way to small even if they did.
I stand by my thesis that if not true the company has bigger problem such as legal ones.
They have had ample time to retract their claim of meeting all endpoints, had they found out it was not true.
8ks still reflect this information.
The dilemma is, sell since legal action will destroy the price short term, or hold thru the storm and potential P3 PM read out.
As you mentioned we shall see, neither of us has the data.
No is not insane, other companies were granted AA on P2 data.
We need to see the n values to determine the sanity.
We are talking about AD here.
Insane is not understanding We are not a just a better mouse trap.
We might be the only safe trap.
Yes that is a fair one, keep them coming.
Only objection there is that the share price didnt react like other times we got disappointing news.
So it didnt back fire as much as exclaimed.
My expectations were never big on OLE moving the needle, I suspect you weren't expecting it to either. (but is hand sight bias now)
It was never going to get us closer to revenue, RETT, AD (still to be seen what to make out of the full data) and PD new trial will.
We got a small n and some drop outs which we do not know why.
But the 20/33 did get an impressive rebound.
So much back firing not sure the share price reflects this narrative.
What a narrative, who are these loyal followers again that have lost trust?
Imagine that!?
Somehow it still poseses a good risk reward ratio!
Beats me!
Oh so only those with negative cost basis should stay invested now?
LMAO!
You got it sir! I remain invested on Anavex.
I see nothing wrong to date on the contrary!
But if I did I would of sold and moved on.
GL!
Mayo doesnt carry the same legal liabilities so he can express with more freedom.
Maybe that is what makes it an ass-et?
Hey dont forget motorcycles are assets and owning AVXL is nothing but risk.
This is the logic you are trying to argue against.
LOL
Not from the OLE, from the upcoming PD trial if we can replicate the same results.
But by then we should already have approval from our AD trial as well as Excellence if we can replicate Avatar.
It is a great question, however the effect is large enough to gain approval.
60% improved, 40% dropped out for reasons we do not know.
You forget how low the bar is, I suspect on purpose.
Now lets talk about the ELIGIBLE patients, impressive improvement and impressive data considering the reversal after they stopped taking the drug.
2) a high percentage of ELIGIBLE patients enrolling in an OLE can be far from the number reasonably assumed. Like the difference between about 100 and 33.
You wanted more from PDD extennsion trial?
What exactly did you want from it?
Dr.Jin saw the same data and joined the company.
Pretty sure he knows more than Duncan, specially now.
Oooops.
The opposite is true, PD includes PDD.
So because of our strong signal we are going for the broader spectrum.
Hence more patients to treat.
They cant, they wont let them.
All good, I`ll just keep accumulating on my long and ignore.
Unrealisitc request.
Be an investor.
You have waited this long what is another 3-4 years according to your timeline?
Or maybe the PDD paper is waiting for AD data, to publish both indications under on peer reviewed paper.
Since there is such large correlation between both of them.
Lmao another one bites the dust....
Not sorry that from my view Anavex`s reality is not quite fitting of the short's narrative.
My bizarre analogy is not bizarre, AVXL will sink if they retract their MET ALL ENPOINTS, in AD for their recent trial.
Or if a class action happens due to the above.
My point and view stands, Dr. Jin didnt join a sinking ship.
He saw public data, he saw non public data, and he is still with the company for good reason I suspect.
One of those reasons I suspect is the need of another trial in AD, with how low the bar is from recent approvals.
Hey what do you know, all AVXL needs is a change of CEO?!
Where have I heard that before in the past 7 years??
Sometimes the lack of response is response enough.
The message is never in the message, but on the lack of message.
You subscribe to Dr.Jin joining the company for these reasons?
As an employee?
I doubt it, but go ahead share your thoughts.
I dont subscribe to this narrative sorry.
You dont join the ship when is sinking.
You join after it has sunk.
As during the process of sinking you get hit with collateral damage.
I agree steady also the type of fiber matters a whole lot in my opinion.
I dont buy the whole grains are good for you argument.
If you couldnt eat it as it is I would avoid it.
Rather stick to fruits, and vegetables that do not need to be cooked, is ok to but they dont need to be.
I doubt our hunter gathering friends were chewing on rice, beans, wheat, "real corn" not the fake modern version, as their teeth would have broken down, and gotten bean poisoning.
Most of these foods are relatively new to humans, we have adapted to eating them because of the technology of fire, being able to break them down and soften them.
But it has only been consuming for a few thousand years, I doubt we evolve that fast.
For now I'll let the birds and other animals enjoy them, and I'll enjoy the animals, among the other things I mentioned.
Not funnier than the ANAVEX is trying to jump on the microbiome bandwagon!
Without doing any research about it!
First of he thought about it for 6 seconds I predict.
Secondly would it be smart of him to join a company that claimed to have MET ALL ENDPOINTS in their AD trial, and had months to correct this statement but didnt?
See the legal implications, they are not good!
Or do you think Dr.Jin is speculating like the rest of us?
Excellent analysis Mayo!
Kudos!!
Do they have time to spend time in message boards negating all positive news from pre revenue biotech companies?
Great analysis Mayo kudos!!
If he reads this board, great for him, not sure he is posting in this board, however.
He has other means of publishing his ideas publicly for everyone to verify and criticize without hiding behind a forum alias, he is a verified real Doctor.
So based on both the analysis I just read, Anavex drug is in jeopardy of approval because they didnt use a SPA with FDA? or the Analysis methodology approved by someone outside of the FDA?
Should an investor knowing this information stay invested? Specially with a looming class action lawsuit coming from the "Met all endpoints in AD" not being potentially true.
Just very odd and concerning indeed.
This investor does not subscribe to this Narrative.
Yes that CEO realized that seeking approval and getting approval are two different things.
So he pivoted to waiting for EXCELLENCE, to increase the chances of the latter.
Kudos to Dr.M!!!!