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Perhaps you should point out the mistakes or invalid analyses in Mayo’s papers, in support of your claim that it’s propaganda. You can’t, and won’t. You label it as such for the simple reason that his analysis conflicts with your agenda.
I don’t know, Xena. I’m not familiar with the workings of the FDA. But what you say makes sense. When Missling says “we will be talking with the FDA” that does not mean they haven’t already talked but no decision has been made yet. Schussman’s point about the drafted but yet to be published peer review makes sense to me. I hope Missling submitted that for initial review, after which the actual meeting will occur.
Aye aye. Good luck with it.
Maybe the FDA is already previewing that before setting a meeting?
True. That would provide an easy summary for discussion.
Well the market obviously likes the deal.
There is no valid reason to wait for the peer review before talking with the FDA. Dr. Jin surely knows this. I doubt that is the plan.
Nice work, James.
I don’t personally care whether they manipulate the price up or down. Currently it’s down but how does that affect me? It doesn’t. I am holding for the ultimate outcome of the company, whatever that may be. So are most longs here. Their problem is that the manipulated share affects their psychology. They have no intention of walking away until the company plays itself out but they strongly desire positive reinforcement that it will all end well. The suppressed share price doesn’t give them that, which is precisely the purpose of the manipulation.
Yes, but the point is that obviously hedge funds and market makers didn’t succumb to irrational exuberance. They manipulated the stock up, plain and simple. So share price is not always a reflection of substance. And that includes this suppressed share price.
I know you believe the current price is justified. No need to repeat it. We disagree as to the cause of the price.
So you are saying that institutions had irrational exuberance and drove the stock up to 30, based on nothing?
Yes, in hindsight it was an opportunity to sell at an artificially high price and trade down. Which I did, in the high 20’s and repurchased in the low 20’s. Similarly, this current level may be an opportunity to buy at an artificially suppressed price.
Retail did not run the stock up to 30. It was hedge funds and mm’s. They were not irrationally exuberant they were manipulating, same as they are now in the other direction.
Again, that is your opinion. Mine differs.
If share price is always the result of news/substance then explain, how did the stock run to 30 based on nothing? Answer: manipulation. Same reason it is now at 5.50. It works both ways.
Manipulation is a fact. Ask any current hedge fund trader or mm whom you know will tell you the truth. I know many. Saying this doesn’t happen on a regular basis in small biotech stocks is like saying there is no corruption in politics. It’s just silly.
At least two others here who have actually worked in the industry have also confirmed what I am saying and what I already know. It is far easier, and far worse, since the advent of HFT and trading algorithms.
The reason for a share price is opinion. Others would say it is concerted short manipulation and that the AD results were sufficient to warrant a higher price. In my opinion it is a combination of manipulation and the fact that the AD results were not 100% clear cut with all endpoints met. It is also my opinion that the results nonetheless warrant a much higher price.
It is a fact that the share price has been in an overall downtrend. It is also a fact that it trades up and down in shorter trends. So those who predict a daily decline are incorrect, obviously. That was my only point. The cause of the longer downtrend is a matter of opinion, on both sides.
You are making the same point I did. Nobody is buying shares because of George’s predictions. And nobody is selling because of the FUD either. But some obviously believe that George poses a threat to the short interest. Which was my only point. Enough, the dead horse has been beaten.
In your opinion because their interests align with yours. Does the stock go down every day, as some predict daily? Why is George’s prediction of news every week incorrect but not the former? Is A-273 a sugar pill?
A non-event for a pre-commercial biotech.
Yet the posters who state daily FUD nonsense don’t seem to annoy you. Interesting. Not really. I know why that is the case.
Oh yes, so soothing to me, George’s predictions As it is soothing to you to have a golfer predict a price decline every single day. Actually, more like ten times per day.
I never said anyone should leave. I simply find it amusing that an army has been assigned to stop George. He is viewed as a threat. Meanwhile none of the same do-gooders have any problem with the fudsters who post daily that the stock will go down, the drug is a sugar pill, everything Missling says is a lie, etc. Many of whom claim they’ve owned the stock for years, yet they have literally never made a positive comment about the company.
The most amusing aspect is that you think anyone is buying the stock in reliance on George’s “news next week” predictions. Harping on it is as pointless as the predictions themselves.
To the contrary, his work amuses me in that you and others are obviously quite concerned that George may induce others to buy shares.
He’s so full of nonsense that you and your buddies have to spend all day trying to neutralize him. Quite a threat he poses to your interests, apparently.
What palpable fear? All I see is some faux disgruntled longs spreading gloom, and some real longs who don’t like Missling.
The EMA application will be filed for full approval and then we will wait to see the decision. And we wait for the peer review publication and guidance from the FDA. The rest is fluff and assorted nonsense.
You should wait until you see the final results of the trials before concluding that the trials were poorly designed. You do not have sufficient information to draw that conclusion.
There is nothing vulture-like about the LPC ATM. The terms are the same as the prior Cantor ATM. It’s smart to not do traditional offerings because a manipulated stock like this ends up with the company getting screwed on price. Much better to allow Missling to place small amounts of shares at a time and price of his choosing. We have no need to do a larger offering all at once.
Yeah, nonsense. Trial results are what they are. All that matters is what the EMA and FDA do with them. You will find that out in due course.
Your comment that Missling does not handle finances well simply because he uses ATMs makes zero sense. Our dilution and burn rate has been in the lower end of the range for clinical stage biotechs. That is what matters. I applaud him for using ATMs.
Missling has not wasted shareholder money. He has simply run trials for drugs, same as any other baby biotech does. And he has managed finances very well.
I read posts from the bottom up.
Dr. Jin came in after CTAD.
Dr. Jin is quite capable of analyzing trial results and he has already outlined why the AD results are potentially approvable, whether it be provisional approval or full. The results were better than Biogen’s results, with added advantages in safety, cost, and the administration of the drug.
No. The chance of material news coinciding with the earnings call is minimal.
No, I applied logic. The company recently announced they were greenlit to apply to the EMA for full AD approval for A2-73 and that this is what they are doing. A logical person would not conclude—from the fact that they will soon trial a different compound for a new indication—that AVXL has abandoned the first drug.
It’s simply trialing a next gen drug for one specific indication (Schizophrenia). The premise that AVXL is abandoning or downplaying 2-73 for the other indications that are already in progress is plain old FUD.
He was here briefly pumping NWBO 2-3 months ago. Stock is down 50% since then.
Exactly. The only people who still hype the earnings calls at this point are those trying to induce baseless expectations.
Yep. Flooding the board with nonsense. Dozens of posts per day.
It was a simple question I posed. You said Clay will be missed, so I asked you by whom? Then you turn it back around on me without clarifying your own statement. I’m not sure what’s confusing about this. But I don’t really care either way. So let’s end the discussion.
Yes, but I didn’t say he will be missed.