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but they're not right! that's the WHOLE point! For you to congratulate or calling them right is the tell you're a short!
did you NOT read the PR? How do you say they won, when the peer review for AD results will be published -which may happen any day now- this can go well over $15!
Here's the house researcher Jesse's initial comments I posted here earlier..
Endpoint was met at week 4, but not week 12.
Anavex says that compared to other Rett trials, their improvement (in the dosed arm at week 12) WAS better than competitors. We go back to placebo performing well (or caregivers botching the result).
“Anavex believes to have identified the probable causes”
Walter K also says there was more severe patients in the dosed group and less severe in the placebo group. Obviously with less impaired patients you’d see more placebo effect. Conversely, it would be harder to see an effect in the dosed group. SO, this actually bodes even better for Anavex having a more robust end score compared to competitors.
93-96% of all patients across all Rett trials have gone to the extended trial indicating efficacy and want of caregivers for therapy.
look at your first 3 posts since the news and tell me how you're not celebrating ? you're just a slick short, is what it is but we can all read you
how is RETT dead when the adult's trial met the end points?
you're a short and I don't think anyone believes you have any shares of AVXL..
first comments (From the fb group) as follows
Here goes:
- EXCELLENCE narrowly missed primary endpoint, primarily due to Placebo group performing well.
- this is more annoying than anything as Anavex has already proven at the genetic level that Blarcamesine improves key ASD (autism spectrum disorder) genes in dosed patients vs placebo patients. So it’s not a matter of efficacy - it’s a matter of the placebo patients performing well (or hope of the caregivers which is possibly more likely).
- safety is good.
- Dr, Missling should have dropped this with a CC. Notice he does not specify next steps. That may be because he doesn’t know next steps at this time. Can blarcamesine still be approved in ‘just’ adult patients which met endpoints? Will pediatric need another trial? Perhaps they won’t need another trial. I’ll assume yes, that they will, until told otherwise. But yes, there is possibility they won’t need another trial once deeper post-hoc is assessed and looked at by FDA/TGA/EMA. Perhaps some will approve and others won’t. Again, the problem was with the placebo group. Anavex has genomic and RWE confirmation of efficacy. It’s up to the regulators now.
- a longer trial may also be necessary as efficacy was seen at week 4, which is already 33% of the way through the trial.
Jesse · Admin
Endpoint was met at week 4, but not week 12.
Anavex says that compared to other Rett trials, their improvement (in the dosed arm at week 12) WAS better than competitors. We go back to placebo performing well (or caregivers botching the result).
“Anavex believes to have identified the probable causes”
Walter K also says there was more severe patients in the dosed group and less severe in the placebo group. Obviously with less impaired patients you’d see more placebo effect. Conversely, it would be harder to see an effect in the dosed group. SO, this actually bodes even better for Anavex having a more robust end score compared to competitors.
93-96% of all patients across all Rett trials have gone to the extended trial indicating efficacy and want of caregivers for therapy.
Hey Bourbon, how do you like you turning against a stock after heading to NYC on trains for CCs and more all those year? Maybe you shoulda loaded like the cult believers back around when the stock was pushed down to around $5s? whatcha say? :)
Feel free to list another company that is preparing to initiate anything to this caliber within CNS diseases. The fact that they were adviced for full Alzheimer’s approval by European Regulatory Authorities speaks volumes and you’re worried about a few months RETT delay? C’mon!
He already updated his Linkedin profile >> https://www.linkedin.com/in/david-goldberger-2439a14/
not new.. unlike you, I'm a believer of not just science but the messenger!
IF you don't trust the referee or say your wife, why go in to a game/bed with them? I wouldn't.. i trust and take a CEO's words seriously.. it Wall Street or others don't, its their problem.. and we'll soon/eventually see who was right or wrong.. but I seriously think anyone who doesn't take the CEO of the company (where they invest their time and money!) seriously, and doubt his official PRs that comes out periodically when necessary, should stop spending their time with that company until the CEO changes.. but that's not even a conversation at this point.. just go away IF you don't want to play here.. or else, be respectful to the guy at the TOP of this conversation and has the last word of YOUR time and money in here!
"We are also on track within our neurodevelopmental precision medicine Rett syndrome program to release top-line data of ANAVEX®2-73-RS-003 Phase 2/3 EXCELLENCE pediatric clinical trial in the current quarter of 2023"
did you miss the above statement that bitch slaps shorts in the face?
I see up %11
Mike, Not sure who is behind your alias in here, but I have a feeling your days are numbered in IHUB AVXL message boards spreading negative sentiment.. Go back to what you like, golf or jerking off, but you ain't accomplishing anything in here.. except the longs are buying more and more after liquidating whatever we can... Once this explodes to new ATHs ALL naysayers should stop contributing in here along with Mike the golfer.. we'll just agree its been a roller coaster and AVXL believers won in the end, as Falcon already declared after last week's PR...
Good decision in what aspect? Financially speaking, you’re free to follow and/or take financial advise from whomever you want.. now, If you’re implying Covid advise, you may be right in NOT trusting government / Big pharma associates (again. BP!!?) and no I’m Not vaccinated and I live in Bay Area.. no one forced me or anyone to get the jab to be clear.. (maybe you have ?)
The so called 'pumpers' with positive outlook are following what Anavex management and scientists that are ranked TOP in the CNS arena. They all believe and share the best of their latest knowledge with public as soon as they're ready to say anything thru PRs and/or other methods in media... Now you tell me the other side of the story? why NOT believe these scientists? is it because BIG Pharma that is 100s of times richer than Anavex don't want a competitor to eat from their free lunch?
iggy /others; please dish out his real name and/or his history of what you have so we put an end to this..
All the yahoos in here should also pay attention to Stock twits IF you really claim to be interested in some more information regarding Anavex. (Why wouldn’t you?) Since all you yahoos clearly make the time to prepare and share/write your own hit peaces to spread FUD in here for hours. ( https://stocktwits. com/ badprecog/message/544709687 ) Investor Relations at AVXL clarified as of Friday that Kum Jin, PHD did his own calculations/ analysis INDEPENDENT from what was done and released back in December ‘22 by a third party and hence the difference.. Of course no one here mentions this but we get to read ALL the FUD about discrepancy in the endpoints etc.. when will you guys stop already?
You are responsible for a-) choosing golf/pleasure over timely company / market updates and/or not being on top of your said investment in Anavex for as long as I can remember b-) for constantly nagging about the share price and/or how it can’t hold gains.. these are facts.. I’d encourage you to keep your negativity to yourself and let’s see what the results may be..? Say next week a peer review and/ or a material partnership with upfront money is announced then maybe you’d realize, your negativity and sharing frustration openly here to indirectly affect / bother others was ALL unnecessary and I’d expect you’ll learn a lesson from that and hopefully apologize and be a lot more conscious going forward when you start typing on publicly accessible message boards such as IHub.. the rest of the FUD spreaders don’t deserve this much comment from me, but I truly believe you can keep the negativity out.. TIA
You realize the more you bitch and whine the more the stock goes south on you.. and consequently on rest of us, right? lol
Not sure how you make a BIG move without some initial noise? step by step brother.. baby steps for a baby bio in this play ground full of EVIL predators (big pharma and their evil tactics) trying to manipulate the market and even authorities
Only for a little bit more… if any
Cabal doing its thing down under...
https://www.nbcnews.com/news/world/australia-claire-nowland-95-dies-taser-stun-gun-steak-knife-dementia-rcna86009
If anyone has any doubt XBI is not manipulated cuz of AVXL events, you're day-dreaming or simple just not woke!
It’s also in my email inbox !!
I’ll go ahead and write this before anyone else; Christopher U Missling, didn’t even bother an official response to AF’s baseless attacks and now we know why.. Missling simply is a genius after all..
I predict he’ll buying a ton of AVXL instead…
You and other believers in the good doctor!
George for president ! ??;)
Mohit Bansal of Wells Fargo Analyst just said Biogen is too good to ignore and upgraded BIIB to Outperform.. just watched him on cNBC.. he said its the best risk/reward in the industry.. he just mentioned Vertex Pharma (VRTX) and Abbvie Inc (ABBV) as the OTHER CNS players..
SBFM 1 year Chart is what we'll be looking at in here... soon...
NRSN - Neurosense Therapeutics Ltd - Halted after running from 2 to $6 in 40 min. https://www.neurosense-tx.com/
Came out of the halt with $7+ now
my 11.11 (150 shares) were grabbed faster than i've ever experienced.. the price immediately went down to 10.9 (where bid was) afterwards, and the ask is now at 11.18
Have you seen Nell Rebowe's runway success ? (No one will sleep thru her presentation once they see her!) lol - Sorry this was supposed to be a response to Fitzy's inquiry...
Yes to all you wrote. Thanks.
I wished Dr. M/Anavex did a little more transparency to where they are with FDA and/or some kind of a good news this week to keep the stock price up/ NOT shorted back to 16s (which evidently triggered the sale of my margin bought AVXL shares @ $17.33)
I just got off the phone with Ameritrade, and they explained most of what I knew except that the maintenance call IS A HIT AND MISS mostly. (Something what I was suspecting but didn't see a hard STOP except a phone call over the summer when again stock was taken down to $16s) and 2 random market sale this week to MEET the margin/maintenance call. And yes the message do pop up in both the App and on the web.
I'm pretty sure you and I are not the only ones to have figured how to create 'MAX buying power at any given time'
Ameritrade users/ AVXL traders, this one's for you.
Typically I'd hold on to AVXL shares overnight/at all times (my core holdings PLUS around 1500-2000 shares of AVXL (on MARGIN) and this was never an issue with the margin team, even though the emails keep coming saying 'margin call due immediate blah blah' I just ignored. A few times last summer when stock was also brought down to $16s I actually did get a call from them saying, "what's your plans? Do you want to take action say until the end of trading?" In other words, they actually will go sell it market price for you at the time they think is necessary, say they never reached you, they can sell at that second.
This brings up the 'issue' that has happened yesterday and today (about 20 minutes before I am posting this) My margin shares were SOLD! at the market price, randomly!
I'm confused and yes I'll call Ameritrade as well, but was wondering if any of you has an explanation to this, and/or maybe got inconvenienced, being discouraged from buying/holding margin for some reason?
btw, there's no missed call in my phone or an email sent to me.
ps. Yesterday's random market price was $16.9 - (of course I bought back with margin! right away to hold over night!)
Today's random price was $17.33 - I'm beginning to wonder if Ameritrade somehow does this to a lot of margin people and some algorithm is aware of this situation and we're all under CABAL ATTACK? lol
Thanks in advance
Say over the weekend there is a substantial / material news (a partner bringing in $500Mil) - how can Dr M not mention this during his presentation ? Hope this is more clear.
So it reads as; regardless Dr. M had news, (say an update on fda correspondence of some amazing news or say a partner bringing in more $$$ - how can such news be delayed by 2-:3 days or more ?
how much time are we talking about in here? we have 25 minutes left and it just won't go down and am getting nervous I'll miss the boat...