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He states that every week. You replying to him keeps him going. He’s just a gas lighter.
Good point Tred. Hope things are well.
I decided to listen to todays call. It’s like listening to a call 10 years ago with different promising pipelines or should I say pipe dreams. Put your money to work elsewhere. You will be able to come back years from now and buy at these prices with your profits from actual investments.
I am able to trade options but for some reason it won’t allow me to trade them for AVXL. It’s not a retirement acct. Thanks for the info I’ll give them a call.
My broker doesn’t allow you to buy call options on this. May I ask who you use?
Hey Tred, good to hear from you. Yea it’s kind of a moot point that regardless of what is going on here, the shareholders are the ones getting the shaft. As usual.
If you think Dr Frost is corrupt you should take a look at our DOJ, SEC and other govt agencies. They make Dr Frost look like Mother Theresa. They aren’t going to help the shareholders here recover from a bad investment in a highly speculative company.
Hey Tred, hope you enjoyed your time off and got what you need from it.
I am starting to think that possibly this is like another we experienced and the price is starting to reflect the true value of the company. On the other hand I do agree that greed drives the world and especially the market.
It certainly is not driven by the desire to help the masses.
Is there a law firm that isn’t suing AVXL?
Dr Frost has absolutely nothing zero nadda up his sleeve. I check back once in a while and still the same nonsense. Sell. Get out with what little you have left.
Yea you can’t. Teaming up with this company is the act of a penny stock company. That’s all I think. Hope you bought cheap shares and don’t lose much like most people have.
Are you excited about OPKO selling pet food. To da moon lol
Excellent!! Very well stated and right on the money.
Adam Logal is a complete moron. I wouldn’t hire him as a teller if I owned a bank.
Completely correct.
I’m not sure where your information regarding BRL came from but the management was highly corrupt when OPKO bought them and I’m struggling to remember them being profitable. For rents paid to Dr owned properties they were fined $10 mil for overpaying rent to these people in return for referrals. There is nothing good about anything here. From the lawsuits to the empty promises it stinks and the crap reaches the sky. Just sell and move on. Use the tax loss.
This is nothing but a money maker for the insiders. Sell and move on.
I completely agree. They have reached the point where there is enough of a track record to have to answer to. Just like the so called Covid pandemic. At some point the supposed R&D money has to show some results or that will be proven as a scam as well.
Sounds good
“Selling and administrative” expenses I’m sure
In my opinion it should be below $1 but the manipulation of this stock has been so ridiculous it’s hard to say. It will go up or down when the powers that be decide what they want it to do. It never generates profit so there is no value here in my opinion. You can’t keep expecting something to get better in the future if you look at the wash, rinse, repeat track record. Now the savior is ModeX. I’m betting it isn’t. Look at the money spent every qtr. where is that going?
Don’t believe that. What could possibly make this worth $3 billion? Hit that light switch.
You guys need to turn off the lights on your way out. Sooner than later.
Why don’t you guys put a Trump flag on his lawn. The DOJ, SEC, FBI, CIA, SEALS, Police, maybe even the Coast Guard will all show up and lock him up. Then you will be done with him.. lol
Peeking back in on OPKO. I saw the latest PR. This is definitely jumping the shark. Ask yourself, what legitimate so called pharmaceutical company would try to sell veterinary products to China customers online? This is embarrassing.
In spite of our “leadership”
I check in now and again and I literally never understand wtf you are trying to say. Since you are the one mostly posting I am convinced this is still a ridiculous place to waste time or money.
Bought more here. If they want to sell I will buy. Let them panic. ☺️
FYI from somebody that was fooled for years. This is wash, rinse, repeat. The latest is ModeX. They will ride that for as long as they can. It’s possible that by the time the ModeX run is used up , Dr. Frost could be gone. Don’t waste your time or money here. Wait for the pull backs and sell for small profits on the bounces. I made a quick 20% on a small investment through options. There is no value here. All in my opinion of course.
I couldn’t resist adding more here.
I read this and looked up and saw a pig flying ?? a momentary lapse of reason? ??
Hey Tred, long time.. hope your time off was refreshing. I have taken some time away from messaging. Just tried to buy some call options on this but they aren’t allowing it right now. Haven’t read the thread but wondered why?
CEO of Graviton Bioscience on Fox Business right now. Talking about new Alzheimer’s drug
Hey Tred, I literally just finished listening to OPKOs presentation. I didn’t realize Dr Frost was relinquishing this role either. It has to be a good thing. I am not saying I see the company going anywhere but it has to be a step in the right direction. I think it was good presentation and if it weren’t for the history of the company I might find hope. When I heard Adam Logal was there I knew it was more of the same.
I haven’t listened to Dr Misslings presentation yet but plan to hopefully this weekend. I am cautiously optimistic about the chances for AVXL. Time will tell but unless the usual manipulation by big money somehow affects them it seems like they have a possible game changer in the works. Thanks for the post and I will give some feedback after I listen to the presentation. Hope your other interests are going well. Thanks again.
$26k per year for Biogens FDA approved drug? I am interested in your comments even though I think I have an idea what they will be. ??
I think it’s somebody or some people trying to move this dead weight. It’s not going anywhere in my opinion. There is definitely nothing happening behind the scenes that makes people think that is the reason why Dr Frost hasn’t bought lately.
OPKO Health Inc. shares get a strong sell rating from us for its own failing financial health and collapsing price.
The company benefited from COVID-19 with strong revenue in 2020 and 2021 for its BioReference testing segment but it did not last.
The optimism of its octogenarian leader is refreshing but not reassuring despite him spending hundreds of millions of his own money apparently keeping the company afloat.
We do not see a cure for OPKO Health, Inc. (NASDAQ:OPK) shares as the price tumbles. We rate the shares a strong sell.
The company develops original drugs, and imports and sells pharmaceuticals around the world. Its BioReference Laboratories diagnostics division is a major testing operation for COVID-19, oncology, urology, women's health, maternal-fetal medicine, and genetics.
The stock is not covered by many analysts but they tend to be positive.
We do not see a cure for OPKO Health, Inc. (NASDAQ:OPK) shares as the price tumbles. We rate the shares a strong sell.
The company develops original drugs, and imports and sells pharmaceuticals around the world. Its BioReference Laboratories diagnostics division is a major testing operation for COVID-19, oncology, urology, women's health, maternal-fetal medicine, and genetics.
The stock is not covered by many analysts but they tend to be positive.
We once owned the stock and got burned. That didn't deter us. Our March 19, 2022 article suggested OPKO Health has upside potential. Seeking Alpha's Quant Rating at the time was a buy. The rating was held throughout the first quarter of '22. It turned to 'Hold' and then 'Sell'. Near year's end, the Quant Rating is a 'Strong Sell'. The 2020-2021 motivations for good revenue and earnings faded.
The shares fell 5%. Top and bottom lines missed estimates in Q3 '22. EPS missed by $0.03. Revenue in Q3 was down 53.4% Y/Y and missed estimates by almost $4M. The -$0.11 EPS last year will be the same vicinity for Q4 '22.
The share price slipped from $5.15 to $3.67 in the first quarter of '22. Nine months later the shares sell for $1.10. The pattern is clear: the stock is down 76% over 10 years, down another 76% over the past year, and -76.88% YTD. Concomitantly, biotech industry stocks have done better.
iShares Biotechnology ETF (NASDAQ:IBB), with $10B in assets, is +~23% over five years. The IBB share price is down 13.35% YTD beating the S&P 500 (SPY) which is -19.84% YTD. IBB has a strong buy Quant Rating. It pays a small dividend. OPKO never paid a dividend. The next earnings report is expected on February 23, 2023.
Hedge funds sold almost 2M shares in the last quarter. The number of funds holding OPK shares slipped from 19 to 16 by the end of September. Massive stock purchases by Dr. Frost, a few close associates, and a trust he controls seem to keep the company afloat.
OPKO's Artist
Dr. Frost built his fortune and reputation as a self-made turnaround entrepreneur and scientist. According to Forbes, Dr. Frost took over Key Pharmaceuticals in 1972, fixed its asthma drug, and sold the company for +$800M. He sold Ivax drug maker for $7.6B. By 2015, his personal wealth topped an estimated $4.5B.
He is heavily invested in OPKO through Frost Gamma Investments Trust. Dr. Frost is the trustee. His slipping fortune, now valued at $2.2B perhaps reflects the fall in OPKO's share price. June through the end of November '22, Dr. Frost is reported to have bought 6.06M shares including 500K last month. He and a few associates own 46% of the company. Dr. Frost reportedly invested over $600M in a company with an $880.8M market cap.
Dr. Frost invests these mega-millions in OPKO because he believes in their products and potential commercialization. Annual revenue has gone up but it has not been a steady climb.
r. Frost told shareholders in 2007 he is enthusiastic about the drugs treating obesity, type 2 diabetes, and prostate hyperplasia, and the FDA approved (in 2016) drug Rayaldee. OPKO was developing a testing program.
At this time, OPKO Health, Inc. does diagnostics and sells pharmaceuticals in the United States, Ireland, Chile, Spain, Israel, Mexico, and elsewhere. The company's BioReference Laboratories offers esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare. It has a novel diagnostic instrument system to provide blood test results in the point-of-care setting; it also offers 4Kscore prostate cancer testing services.
BioReference's COVID testing greatly increased revenue but panned as testing mandates were set aside. In 2021, OPKO introduced Scarlet Health in-home testing; this is a booming field, as we described the industry in another article.
The company has trials going for an orally administered once-weekly administered peptide for the treatment of type 2 diabetes and associated obesity. NGENLA is a once-weekly human growth hormone injection that completed Phase III clinical trial in partnership with Pfizer, Inc.
The company develops, manufactures, and sells pharmaceutical, nutraceutical, veterinary, and ophthalmic products; it commercializes food supplements and over-the-counter generic products. OPKO imports and resells cardiovascular pharmaceuticals, vaccines, antibiotics, gastrointestinal products, and hormones. Pharma revenue dipped 12% due to volatile foreign exchange rates this past year and headwinds in Chile and Europe. Rayaldee sales were down in Q3.
OPKO is a Pill
We cannot forecast a healthy future for OPKO Health, Inc. Short interest is approaching a high of 10% as the stock dives toward a dollar. The force majeure is 86 years old Dr. Frost. He is spending a personal fortune to help float the company. The November 8, '22 shareholder presentation and earnings statement were disconsolate, in our opinion.
Between July and September '22, management cut its workforce from 4,300 to 3,300. Its website claims the company employs over 5,500 in 9 countries.
The company wants to cut $140M per year in expenses.
R&D and marketing might suffer the most.
New partnerships and relationship building with other biotech and pharma firms that management boasts to market and sell products sound time and resource-consuming.
In the Q3 presentation to shareholders, The President and Vice-Chairman warned shareholders that
It is imperative that we also align our infrastructure and related costs, with current testing volumes for COVID being reduced to endemic levels, in addition to inflation pressures…while pursuing efficiencies in virtually every area of our business, including rationalization of our testing platforms and looking at opportunities to use lab automation and machine learning where possible.
2020 and 2021 were better years for OPKO shares; the share price rose to over $5 each as BioReference revenue flourished. Scarlet®, the division's mobile patient testing centers serviced millions for the novel COVID-19, influenza A & B on cruise ships, in the National Football League, at 17 pop-up testing facilities, and more. Then it was over. The operating loss for the diagnostic segment was $49.5M in Q3.
We do not see any scintillating news that is going to drive up the share price. We cannot see any potential for an investor to do anything but take a tax write-down with a strong sell rating. We admire Dr. Frost's business acumen and scientific contributions. He also puts his money into his passions. Most of all we admire the optimism of this octogenarian.
Very possibly. I had respect for him for building his wealth in this area. That has all been taken away. Whatever he does, I’m sure won’t be to our advantage.
Hey DeGen, IMO this is hopeless. Nothing they have promised, stated in their CCs has don’t to fruition. 4K, OPK88033, Claros, Rayaldee, Somatrogon.. the list goes on. What I am saying about fruition is anywhere near what they promised or alluded to. Their latest ModeX purchase is just another non event. Their CEO stated he would be having a call giving more details about the team and the company.. crickets. Dr Frost hasn’t bought lately, which means nothing anyway. They did nothing for the shareholders with all the business from Covid testing. Thr biggest scam I have ever seen. If they were to sell they would be very lucky to get a couple bucks a share. We were all lied to.
Where there is this kind of money potential there is absolutely rigging and corruption. Follow the money is the truest statement ever made