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More! Then acquisition.
I met Pete Falcone during his comeback attempt in 1987 winter league in the Dominican Republic. He played for La Romana. We went out had dinner in the sugar cane fields at a home. He was a little off, but a great guy, awesome talent that I watched for about 10/11 days.
Competition; (?)
1) Product already being used “Gamatile” and being received quite well.
2) Boston Scientific just received FDA Breakthrough Device Designation for ‘Y90 Glass Micropheres’ (Therasphere) for GLB. After receiving approval for hepatic cancer.
Read the entire paragraph below. BSC will be working with GLB patients with this approval and with immunotherapy products. ??What other company (immunotherapy) is located in the greater Boston area?
From BSC;
The FDA approval and the recent NICE recommendation will expand access to TheraSphere, which has demonstrated improvement in both survivability and quality of life through 20 years of clinical trials and real-world outcomes in the more than 70,000 patients globally," said Peter Pattison, president of Interventional Oncology, Peripheral Interventions, Boston Scientific. "We expect to continue to focus our efforts on bringing this treatment to more patients, both by planning a randomized trial to study the combination of TheraSphere and immunotherapy in patients with HCC not eligible for curative treatments, as well as further investigating the therapy for different cancer segments, including prostate and brain."
For more information on TheraSphere, visit www.therasphere.com.
Henry Ford Hospital Detroit, MI
Researching more...
http://ow.ly/EObe50Dy9Ad
Agreed.
Plus... does anyone consider the FDA just might (?) have some things on their plate (Covid vaccines) that have been and continue to be thrust to the forefront. Understand that GBM is very important but, Dvax just may not be their highest priority.
Maybe
Here’s my once a year post. I’m in at $7/share, yes $7! Been around a while. Not going away, long. But, why keep beating yourselves up with the same round & round data. LP will disclose whenever. She does what she wants. Unless you all just look at this as therapy, yikes. Once a year.
Some of us were in NWBO before others. I’ll be around until the end. You just keep chasing your key board, I’ll go play some golf and wait.
Anybody think I’ll get my $7.00/share out of this?
I thought somebody my show some interest. ???????
I been long for about (6) years, still waiting. Watching other modalities pass us by. Please review as I only post about once a year. Thanks.
https://bddy.me/2TOZ9ny
Get the CANCER out! Impotence and incontinence CAN be corrected!! Have been for over 40 years! The treatment options (penile implants and artificial sphincter) are proven effective! Get the CANCER out! Can also pursue vacuum device, injection therapy, kegel exercises, MALE slings, prior to implant surgery. Both are in the upper 90+% effective and satisfactory rates.
So your solution is?....
Sell? Why? You buying? Why?
Maybe we are just in NWBO because we believe in something!
What FACTS do you have on the science?
Are you in THE NWBO LAB?
Are you running 'models', but don't have any FACTS? Speculating is what you are doing with your 'non-valued' commentary! We are SPECULATING with our CASH (that's real $$$$s and has some intrinsic value).
Posted about 6 weeks ago.
"Remediation"
I work for a medical device company, has been around for 40+yrs. then about 4 years ago paperwork and trails were looked at by the FDA. The company has been able to make corrections but we have been prevented from new product launches. We have had to show the manufacturing process' are all within the 'tolerances' originally specified when submitted to the FDA. So, I would imagine the depth NWBO must have to go through in order to sync the various manufacturing sights and remain compliant. Cost has been a huge hinderance to get this done.
Ok let's ALL Double our positions.
"Let's gooooooooooo"; John Belushi
I wonder with all the various locations of manufacturing, could there be a REMEDIATION requirement going on? NWBO may have varying production at each facility raising issues regarding lack of consistency. ? Documentation requirements for current and PAST indiscretions. When you (NWBO) do not have any in-house resources to conduct this activity = $$$$$$$
Hmmm, I wonder what I'm doing in the operating room as a 'surgical representative' then? I'll call HR!
Boston Sci
You know there is THE CLUB-CLICK here! This will probably get scrapped. Frustrating, no I find it humorous! Because, really unless someone here works for NWBO (I mentioned it). Then there is NO FACTUAL information shared; models, speculation, conjecture,... Maybe legitimate criticism of management and suggestions for improving management strategy. You either believe or you don't, 'bet with the house' (don't pass) or BELIEVE the science will prove itself (pass). Patients/Patience is what we all need with NWBO (2nd time). Delete worthy?
So we (longs) are hanging on to a 'loser', so says you! Why are you hanging around? Most people strive to 'win' and believe what they do strives to that end point. You seem to enjoy watching and experiencing losing? Sad really. Don't think you're in the labs doing NWBO work, are you?! So, you really don't KNOW and can only "predict" (your word). I suppose since I'm here and a 'loser' already, I'll wait a little LONGer and get the results from someone like Dr. Linda Liau. Someone, who as a scientist and researcher, will give factual results - not just a prediction. We all know where you are positioned on NWBO so, from a favorite movie (Heartbreak Ridge) the platoon of losers lead by Clint told the other Sargent to just "go away" and that it was "mind over matter", they continued "we don't mind and YOU don't matter"!
LP owns shares correct? Is she selling? NO. Why doesn't she sell them ALL and get out now why she can? She believes in NWBO. When is enough $ enough for LP? Obviously, not enough yet or she would, with your line of thought as this is as high a pps in many years. Same line of thought for Cognate and ALL the shares Cognate (LP) owns of NWBO. She/Cognate get out now while the getting is good, right?! Why not? Not like NWBO is paying a dividend, she is not content and believes there is more ($ AND better results) to come which equates to HELPING patients, which LP ultimately believes in, and that too will translate into more $. She observed the tough lesson of Enron, we all know that. Think SHE wants to go down that path? NO. NWBO is a fledgling organization, running lean, rewarding those that invest their time with 'high risk/reward' shares of a company that may or may not succeed. These are BELIEVERS! That's how high flyers work. We have been given an opportunity to invest and take that chance too. I think you may have to reevaluate and ask yourself; Are you REALLY a BELIEVER too?
Ramos @ NWBO since May 2014 (Madrid, Spain), Lye @ NWBO since Jan 2015 (Hawaii), Hunt (consultant) @NWBO since Feb 2015
This could also explain why a move to The UK is important to NWBO - 'Inversion'.
When the production of all the vaccine increases to such high volume, we will be talking about $100k per treatment PLUS. So, why would LP want to pay exorbitant TAX rates in the U.S. and Maryland? Maybe I'm off base with a full explanation, but I think it may contribute to further the conversation along, maybe?
WHY IRELAND?
Ireland is not the only home for inversions Britain, the Netherlands and Switzerland are also popular. Pfizer made a $118 billion bid to buy AstraZeneca Plc <AZN.L> this year, so it could move its tax domicile to Britain, but the pharmaceutical giant was rebuffed by its target.
But for tiny Ireland, the deals can be vast, such as Medtronic's <MDT.N> $42.9 billion takeover of Irish-domiciled Covidien <COV.N>, which led to a near sixfold rise in the value of Irish-based M&A in the first half of the year - and almost 20 percent of all of Europe's, research by information services company Experian found this month. [ID:nL6N0PK4JL]
It is not just tax that encourages inversions from the United States to Ireland.
Ireland's Arthur Cox, legal advisers on deals worth 56 billion euros this year, according to Experian, lists the attractions of a legal system similar to the United States', no shareholder rights to interfere with executives' pay and limited rules on the "transfer pricing" of intercompany transactions, which can also be used to shift profits to avoid tax.
"If you look at what Jazz Pharmaceuticals <JAZZ.O> have done (after buying Ireland's Azur Pharma in 2011), they're actually building a center. That's the type of thing that will strengthen the case for inversions - real employees, bricks and mortar."
"SLIPPERY SLOPE"
One Dublin-based M&A banker, who declined to be named, said Ireland's Office of the Revenue Commissioners, which assesses and collects taxes, has been on red alert since late last year around any sort of structure or deal that might be seen as trying to evade tax.
"It would be a lot harder for an overseas company to set up in Ireland now versus even two years ago unless they were bringing a large number of jobs with them," he said. "They are not as forthcoming or facilitative as they used to be."
A spokeswoman for the Commissioners said they are always on the lookout for such structures and apply the relevant legislation fairly to all entities tax resident in Ireland.
"What companies want is certainty. When we visit firms in the States and elsewhere, they mightn't always be able to find Ireland on a map, but the 12.5 percent rate is nearly a mantra," Dillon Eustace's Tiernan said.
Read more: http://www.businessinsider.com/r-ireland-has-too-much-to-lose-to-deter-us-companies-re-homing-2014-30#ixzz3dqfWKs59
Thank you Flipper.
That did work out rather strangely with the timing of my inquiry and your finding/correction in the Smith report.
Thanks again!
Flipper,
Respect your insight and your TIME that you invest in this board. Thank you!
So, apologize if this may not make sense or is to far 'fast-forward' of a question to delve in to.
NWBO is treating patients that have failed other therapies, late stage, if you will worst of the worst. My understanding.
NWBO is progressing with rather exceptional results, as we all have been witnessing. So, the question I am pondering is; What type of response, from those treated, do you think DCVAX - L/D patients would have should their malady be discovered in an earlier stage (1,2,3)? Would you hypothesize their immune system may respond more vigorously, because it may be less compromised? Prolong life even longer? Again, thanks for considering even just a brief reply!
Been here about 2 years and only chime in periodically.
Continued good fortunes to you and all here seeking a NEW SOC for those who are suffering.
Thank you Hodge!
Must invoke religion, God bless your wife and ALL your family!
You said; "It goes like this....The site gets paid by NWBO for each patients treatment and the various services involved like things the routinely do anyway (bloodwork, etc)."
Well, then these sites DO have incentive to recruit patients, and only receive payment when patients ARE recruited - right? According to what you say! So, the site needs to recruit to receive incentive, that's THE Sites responsibility. You also state staff is trained at these sites. In what industry, business, corporation,....HOSPITALS are individuals/staff trained if there is NO intent for the training to be utilized? And, it will be, when the PATIENT IS RECRUITED in to the program by the Institution.
I wouldn't have you trained on 'Mac' if all we used was 'Windows', unless I knew and was anticipating THAT skill/knowledge was going to be necessary in the future.
Wouldn't you agree? Or don't you ever agree?
Why would a Center go online? To say they were, just because?
To have their facility associated with a success or failure? Would you think they would go through a process to be involved to, NOT want to be involved? I would think a lot of administrative procedures, hoops, and signatures are required - wouldn't you? They have nothing better to do?!
No, I would think at each of these facilities someone has bought in to DCVAX. That individual is the 'champion' of this project. They have a vested interest in a successful program and are presenting this therapy/trial to the appropriate
candidate-patients. This is a BIG decision for the candidat-patient and their families and much to consider.
Not a short of NWBO! Agreed.
But, RK and Pyrr both 'leave' the board within 24-48 hours of each other!?
Who conversed with either of them more than each other?!
Just saying!
"Science, she blinded me with science!"
Thomas Dolby
If 'it' works, will the stock price go up? Probably YES
If 'it' does not work, will the stock price go down? Probably YES
Does 'it' work? Ohhhh, we're not privy yet (yes or no)
So, really it's about the 'end'! Not your 'short-comings-on', you know who I'm referencing. Why is it you EXPECT the final answer right now? You know that is not feasible, not from anyone on this board. Only when the Phase are complete and
L and/or D have proven their success or failure. As said, so many times before, this board has NO influence on the science. But, we try to understand the science from this 'sandbox', you see we're not allowed in the REAL one. Sorry, I don't think this board has any influence on NWBO management either. Deal with it, it is what it is.
Spew your disgust, dissatisfactions, frustration, whine, ..... blah, blah, blah, blah, blah. You can do that. This is INVESTING not a Guarantee! Does it get any more speculative than Biotechnology? You know - NO IT DOESNT!
Does 'IT' work? Not privy yet! (yes or no)
That really is the only fact we do know!
The science will tell us and that can't be rushed.
This isn't 'cheerleader stuff' either, just very simple logic. I will see this to its conclusion, success or or not.
Maybe they will influence LP to hire a CFO and surround her with all the 'right' people she will need at NWBO. These quality individuals certainly know other Biotech Savvy Professionals. IS, Woodford setting up an 'operational plan'? His hand may only get heavier as his investment grows and LP gains more trust in him.
Just my 2 Cs
So, you summarize my post - Gambler. Yes, true!
Sorry, just a sponge in the medical industry.
What about the 10 questions I asked?
Here I'll answer the first one of yours; "Don't we have a right to know and ask?"
1) You should 'ask' first then 'know'. But, know what your asking.
2) You/We have a right to 'ask', absolutely. To 'know' or answered with what You/We want to hear, not necessarily. Sorry.
So, let me summarize you. This is all you do!
Is that 'fair'? I think not.
For me to post twice in one day, excessive. Gotta work my real job, go pick-up my wife from work, walk the dog, watch a little PGA @ Pebble Beach,.... RELAX.
Guess we approach this stuff a little differently, I'm certain you'll agree with me on that point!
Doomsayers,
I am long, I don't own a ton of shares, I own what I can afford to lose = value, probably (2) trips to Vegas $.
Why did you, are you invested in NWBO?
Is it a plan to double up and go?
Have you ever owned the stock of the company you worked for? Have you ever worked for a company that is listed?
Has the CEO of that/those companies ever told you what was 'coming', so you could make a strategic decision?
If you were privy to some information, were you informed of specific black out periods?
At what price would/will you sell, PROVIDED you are long of course.?
Really, I don't think this board in any way influences LP. In fact I don't think Woodford or Meheil even have much say, if any.
I don't think they are, NOR ARE YOU, of the 'Carl Icahn' status YET!! So, WE ALL vent. Are you so confident you will intimidate some to sell? I'm sure you will be teed-off with this line of questioning and commentary. You see, I am a believer/long. I look at much of this as the big CASINO. I am gambling this SCIENCE is going to work. From my perspective the science trumps all. Have ALL the prominent entities involved with DVax research been dooped? Really? Really? I read what you present and all I hear is your desire to 'crap-out! Maybe the clean-up at the U.K facility is just that, cleaning up a manure pile to ensure there is not excess methane gas present.
So many of us are on the 'Pass-Line' and risking what we can that one day it will PASS the FDA. When it does, the $ will take care of itself for us LONGS, with odds. Because of the SCIENCE! I choose not to be cynical, the 'Point' is coming!
You, are on the 'Don't-Pass' - and that is all I hear; DON'T!!Betting with the house for your one for one return.
Good luck, but I am rooting against you, and your strategy/approach to NWBO.
And you against us, that 'Buy-and-Hold'!
Think ALL will be interested in this 1 minute clip and an upcoming episode on HBO. Don't think it has been posted before. Will be on 2/27/15 HBO
GGold
I, like you have been around for some time and rarely post! Hyway just posted and he got me thinking, scary thing.
How many ways can you skin a cat? How many ways can Pyrr et al run the numbers? After awhile it's the same thing, just rephrased. By no means do I think it was unimportant, I know I had questions for clarification and I'm certain I/we received some valuable information and education. I've noticed overall posts are down significantly, by ALL. We LONGS only need to wait, let the trials run their course. LP isn't going to change until SHE wants to, not because some here think they will influence her. Let the next sets of data be revealed. I feel quite confident the analysis will pickup again at that time. By now, if you believe you will stay long with what you are comfortable risking. Wait for approval, should that happen. Not sure I contributed or revealed anything new, so I will slink to the back of my sock drawer with my shares I have stashed away. Come out again maybe next February 2nd, oh Punc Phil has that job already doesn't he!? GLTAL's
Austy,
RK certainly doesn't need my defense as I post here about every other month but, she was replying to my post. Not sure if you took the time to read so I'll leave it here for you. I have NO bones to pick here with anyone, but man....to much stress around the holidays can be damaging to one's health. Just sayin!
I said;
"Speculation, Potential, The unknown, Modeling,...... so much to consume, absorb, try to understand from THIS boards perspective. I've learned a lot from so many (Thank you!). But my take away is WE really don't know when these vaccines are going to come to fruition. Sorry we don't! We now speculate late 2015 or 2016 or MAYBE 2017. For those of you who want answers now, will that ease your mind? No, you'll want more information that doesn't come, at least not until trials are completed, AA, BLA,... Don't like how NWBO is spending the $ , then this may not be the place/stock for you. For the 'clinicians' on the board, it's great you share your knowledge of the science with us and each other. But, I don't think any are involved directly with any of the phased studies. So, it's speculation. For me, this comes down to what I have invested in NWBO is basically shares that are in the back of the 'sock drawer'. I don't see NWBO being a 'day-traders' dream. I don't see NWBO moving at lightening speed thru the trials, not a favorite child, more like a red headed stepchild. No offense intended to anyone, so please don't take that personal. Curious how many on this board would jump ship if the pps went to $10? $20? So many talk the big game of $100, $200 per share. Many will jump at $10! Personally, I'm here for the long haul - win or lose! I want to see if I have the guts to ride this to $200 OR MORE! I'm long I do believe this methodology IS THE NEW SCIENCE and future of medicine. But, sorry it's just not ready for prime time. Not because we don't want it to be. But, because IT (L and Direct) are going to have to prove themselves to so many that sit on other 'boards' - FDA, et-al. And that isn't happening for awhile. Sorry, all of our collective desires, modeling, and speculation are not going to change the ACTUAL science being utilized on THOSE UNFORTUNATE WHO ARE ENDURING SUCH HORRIBLE DISEASES. We can't lose sight of them and their families!!"
Speculation, Potential, The unknown, Modeling,...... so much to consume, absorb, try to understand from THIS boards perspective. I've learned a lot from so many (Thank you!). But my take away is WE really don't know when these vaccines are going to come to fruition. Sorry we don't! We now speculate late 2015 or 2016 or MAYBE 2017. For those of you who want answers now, will that ease your mind? No, you'll want more information that doesn't come, at least not until trials are completed, AA, BLA,... Don't like how NWBO is spending the $ , then this may not be the place/stock for you. For the 'clinicians' on the board, it's great you share your knowledge of the science with us and each other. But, I don't think any are involved directly with any of the phased studies. So, it's speculation. For me, this comes down to what I have invested in NWBO is basically shares that are in the back of the 'sock drawer'. I don't see NWBO being a 'day-traders' dream. I don't see NWBO moving at lightening speed thru the trials, not a favorite child, more like a red headed stepchild. No offense intended to anyone, so please don't take that personal. Curious how many on this board would jump ship if the pps went to $10? $20? So many talk the big game of $100, $200 per share. Many will jump at $10! Personally, I'm here for the long haul - win or lose! I want to see if I have the guts to ride this to $200 OR MORE! I'm long I do believe this methodology IS THE NEW SCIENCE and future of medicine. But, sorry it's just not ready for prime time. Not because we don't want it to be. But, because IT (L and Direct) are going to have to prove themselves to so many that sit on other 'boards' - FDA, et-al. And that isn't happening for awhile. Sorry, all of our collective desires, modeling, and speculation are not going to change the ACTUAL science being utilized on THOSE UNFORTUNATE WHO ARE ENDURING SUCH HORRIBLE DISEASES. We can't lose sight of them and their families!!
LOL!
This was before I'd realized this was 'another subsidiary'. Still chuckling - 5,6,7 Minutes later.