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I don’t think there will be one anytime soon. If anything it would have been done already to attempt to uplist. IMO. Also, ipix last I looked was around 200 million OS. I’m hopeful in every way that this increase in AS will allow our next partner for OM to take a large equity stake in ipix I hope they buyout MOFO and take a 100 million position at a much higher price.
Small dollars indeed for the first deal. But first deal it is. People may not realize that this deal gives a foundation for IPIX. I would assume that AS will move at light speed to recognize this possible revenue. In turn this validated B upon every step for ipix. It’s free PR and validation. Leo could legitimately close the doors of ipix and take no salary and make up to 24 million in milestones and 6% min on royalties. We don’t have to do a thing moving forward.
It’s the smallest indication, so I am okay with the deal...and look forward to the free validation and PR to move to a multi billion indication like Crohns
Jmo
We need a good article/interview IMO. LEO we need something where you can answer truthfully and lay it all on the line...these types of questions:
1) Hindsight is always 20/20. We could all sit here and ask you "why did you not exercise more stock with Aspire when the stock was in the $3 range?" However, can you give us more detail on your relationship with the MOFO and is our agreement under control? DO you foresee a time where we can possibly partner one of our drugs(indications) and have said partner take out the MOFO and become a large shareholder?
2) With the share structure eclipsing 200 million OS, and the upcoming vote to move the AS from 300 to 600 million, what are the companies goals with that type of move?
3) We all know you feel there has been nefarious characters who have attempted and successful in taking down this companies share price, do you still have justice in your sights? Does the company have any continuing relationship with Mr. Sullivan?
4) About this time last year IPIX had a 3 milestone goal with ASPIRE and fell short on all 3. Can you give more insight on all 3 failures.
a) What happened with Prurisol?
b) Is there any plan to achieve BTD with OM?
c) Was AS the 3rd party BP that you had in sights for the final milestone?
5) In regards to B-OM, most shareholders get the feeling that this indication is following suit as ABSSSI. Can you put shareholder nerves to rest and express the plan to move OM forward at lightspeed? What are the next steps and where are we at?
6) Has there been any interest in ABSSSI over the past 2 years since the announcement of being phase 3 ready?
7) Shareholders have seen PR updates on Kevetrin over the past 2 years but can you offer how far the testing of Oral is? In the same topic, is there any way we can maximize potential of an IV Kevetrin?
8) How many CDA's do we currently have open? L)
These are just some as I listen to a CC so I can't really focus, but I think Leo needs to come forward and regroup the shareholders. IMO, ever since Dr. B has come on board the company has been much more tight lip and this is a PENNY STOCK and there needs to be much more cheerleading and open conversations. Without a natural cheerleading from management, this will continue to just get eaten up by MOFO dumping. We need new eyes and with social media these days...and a true ORGANIC and PHENOMENAL product line...this company should be much higher on speculation.
Cheers!
The first domino fell. I believe we see another one shortly.
Agree. It could be a dollar. The main thing to take away is validation by a billion dollar BP.
Leo went for the smallest indication at this point imo for the fact of gaining that first validation and taking one for the team. The dominos will begin to fall.
Now Alfa gets all knowledge of any possible deals upfront and has 30 days to counter. It’s going to help move deals imo.
OM is next imo.
Other IBD will be after that.
I’ll take the 24 million if milestones are met...but ipix does not have to do a thing which is huge. It’s all on AS to move UP forward. No cost to ipix.
I do like the Right to first refusal as it creates transparency and competition. Every offer has to be disclosed to AS and therefore starts the 30 day clock for AS to make a move and counter offer. They have a window to keep their place in line.
However I feel OM is the next drug to be partnered and has nothing to do with AS. Validation by a billion dollar global BP was the first domino. OM will be much bigger. IMO.
Alfasigma is taking on all development and trial costs. Let’s hope they can move B-UP through reg trials at a record pace.
We just sit back and concentrate on K oral and B OM now.
I do like the first rights. Because it now puts a little pressure on parties interested. It may move the needle a little quicker on other deals.
Alpha's PR in English: (Translation provided by GOOGLE)
Alfasigma agrees with Innovation Pharmaceuticals for
develop and market Brilacidin in the treatment of
Ulcerative Proctitis and Ulcerative Proctosigmoiditis
• Innovation Pharmaceuticals & Alfasigma announced an agreement for
Brilacidin, in the treatment of Ulcerative Proctitis and Ulcerative Proctosigmoiditis
• For Alfasigma it is the second agreement in a few weeks that strengthens
pipeline and portfolio in the Gastrointestinal field
• The agreement starts from a base of 24 million dollars
Bologna, July 23, 2019 - Alfasigma Spa and Innovation Pharmaceuticals (OTCQB:
IPIX), a biopharmaceutical company based in the United States, have entered into a licensing agreement
for which Alfasigma will develop and market worldwide Brilacidin for use
local, for the treatment of Ulcerative Proctitis and Ulcerative Proctosigmoiditis (PU / PSU). There
Proctitis is an inflammatory disease of the rectum, which when extended also to
sigma is called Proctosigmoidite.
PU and PSU are therefore attributable to chronic intestinal inflammatory diseases (MICI,
also known as IBD - Inflammatory Bowel Disease: together they represent one
chronic and autoimmune condition difficult to treat affecting about 10 million people
all over the world, including 200,000 people in Italy.
Brilacidin will be developed as a new non-corticosteroid, non-biological treatment,
administered by different formulations, Alfasigma will initially develop
topical formulations such as enema, foams and / or gel for PU / PSU.
A few weeks after the announcement for the commercial re-introduction of Zelnorm
in the States - used for the treatment of irritable bowel syndrome
constipation - this is a further step in strengthening the pipeline in the Gastro-intestinal area.
"Alfasigma is developing, at a global level, a specific focus in the Gastrointestinal field",
stated Pier Vincenzo Colli, CEO of Alfasigma. "We are excited to add to the
our portfolio, this partnership with Innovation Pharmaceuticals. The results of the study
clinical on Phase 2 Brilacidin in PU / PSU seem promising and enhance properties
unique of the drug. To advance Brilacidin, we plan to allocate an important one
investment, both in terms of internal resources and expertise for formulations and protection
of intellectual property. "
We are proud to be able to work to offer patients a new and effective option
safe treatment in the management of PU / PSU ", continues Colli" We will also closely follow i
next developments of Innovation Pharmaceuticals in the development of oral Brilacidin, why
we are also interested in new treatments for mici. This agreement, along with that
a few weeks ago on Zelnorm, represents a further enhancement of ours
global pipeline ".
The agreement also includes a right of first refusal for Brilacidin in the treatment of forms
more extensive inflammatory bowel disease (IBD), such as ulcerative colitis and the
Crohn's disease and a first negotiation right for Brilacidin in other gastrointestinal indications. In addition to an initial outlay, the agreement provides for a series of additional payments
based on certain milestones, for a total of over $ 24 million and royalties of 6% on
net sales in the marketing of Brilacidin for PU / PSU.
Information on Alfasigma.
Alfasigma is one of the leading Italian pharmaceutical companies: present in over 90 countries,
has a workforce of around 3,000 people, Research and Development laboratories, and 5 factories
of production.
In Italy Alfasigma is a leader in the market for prescription products where, in addition to the strong focus
on Gastro-Intestinal, it is present in many primary care therapeutic areas. Produces and
it also markets self-medication products, nutraceuticals and food supplements.
For more information, visit www.alfasigma.com or send an e-mail to
info@alfasigma.com.
This is great news. Take the smallest indication and FINALLY sign a deal. Allow the team at sigma to take the trial and formulation and roll it. Forward movement to better solidify the franchise.
Let’s see what happens next to OM
New eyes!!! Slow and steady. Do DD newbies. Great pipeline.
First deal. You are correct
Max. We have dilution. We have no new eyes. That is why it goes down
It’s not hard.
Look back 2 months. Stock soared from .12 to .40 on one buyer and dilution was stopped at that point.
This stock will fly once validation is signed and ipix bank account is stacked with 8 - 9 digits
Yup. I have 10K available tomorrow.
This silence is very good imo.
It’s actually the K. Sept 11thish
It’s quite amusing to see. Full staff today....hmmmmmmm
And that 7 months was just negotiations. Not the initial DD and meetings which started in 2017
10-k due in Sept. if we dont hear by then, you’ll see it posted.
Leo and Dr B are very quiet. Very
I say we see a deal soon.
My company just did another acquisition and it took 7 months and we still are waiting on a few foreign agencies to approve.
Stuff takes time. That was only a 100 million acquisition. I think IPIX sees multiples of that in a first license deal
Great post. Few and far between on this board. Thanks
And Dr B worked for them.....
This is not needed. Leo and Art are planing for EXTRAORDINARY...not good, not great, but EXTRAORDINARY! The fun and games by several future partners over the past 3 years was a learning curve for them. Games will be played but the right partner is going to help setup a phenomenal foundation for Brilacidin to flourish in the market. We are in the right indications my friend. If this is setup correctly, people involved will make alot of money while helping this world. I got my tickets. Front row tickets to be exact.
Much higher. Do not let the long term bashing misrepresent what is possible here.
I am at work, but can offer you my valuation: if B-OM hits IPIX projections in the first 3 years on market, this share price would see double digits. That’s OM alone and thinking the share structure stays below 300million.
Add IBD in a 40 plus billion environment and you are talking much much higher.....
If K can be formulated into oral dose and shows same efficacy ——- you are talking about 50% of all cancers. Much much higher.
Don’t let this board bring you down. And I’m not saying this share price is going into the 100’s but I’m telling you realistically...our pipeline is worth billions at the end of the day if half of the indications prove out.
Can you hear the whispers? Tiab!
Major 9 digit deal being inked?
I’m hopeful! I believe as you do.
Get this monkey/gorilla off our back!
I see greeeeeeen!!
FOMO! Love when it sets in :)
June 6th...last PR, we are almost to 30 days. That would put us at Monday Leo.......release the partnership PR on Monday and comply to the 30 day quiet period.....lol
Oh Lone.....I know I know, there is no such thing! But it’s fun to pretend
I think the hook at this point for our suitor is the verbiage to give first negotiation and refusal rights for additional indications.
To me, the pipeline is extremely valuable and unfortunately ipix currently sits at a very extreme discounted price which allows suitors to have the upper hand. One of the items to lure a BP quicker is to offer up those right imo. B is going to be a multi blockbuster imo so it helps secure the suitor to give up a small stake for UP but allow them to take first cracks at a huge UC and Crohn’s indication if things continue to pan out successfully. Less risk for them but secures first in line seat.
I think we see a deal very very soon.
I’m not sure how much those rights add into the upfronts for a UP deal....but I am anxious to see who
Just need that cash....support.....validation! And the market will go nuts! Too much potential here imo.
Friday at 3 pm. Lol. How many times have I said that :). Leo does hear me.....I know he does.
I’m sure they are finalizing the 2 deals and will announce them shortly.
Great read. Short squeeze from 2 to 78. Love it!
Sounds about right....big buyer comes in about 30-60 days ahead of the big news.
Come on 3pM deal PR. 1 hr before close
Why is this consistently in the high range? 70’s and beyond?
I’ve been here for many many years and have seen your posts for years and normally it is in the 30 range but since mofo it’s been in 70’s and beyond. I think the data is worthless, however it is interesting to see such a high consistent number.
Also Dr B held positions at Novartis
Could Novartis be our suitor? Suggesting BDD Pharma?
Great step forward. Just as the company said they were going to do.
I agree strongly with your post. Mostly old blood in this stock right now. Many of us bought in the $3-$4 and still holding and also 10-20x plus our holdings in the .10-.20 range over the past 6 months.
Bio investing for me was a 10 year commitment knowing I was not going to sell a share unless I got a bad taste. I feel I am extremely lucky to have had the opportunity to 10x plus my holdings with a fraction of the money put in. I consider to be lucky because the OS has no where near increased by that ratio.
But you are correct that the sentiment from so much time and effort on negative aspects and hit pieces have sunk this from the $4.93 share price and we simply need some validation. I have suggested a specific path where and if a partnership does come to fruition to include some unique stock purchase commitments and also require specific communication from our new partner to offer some extremely healthy and free PR to help correct our market cap. I have faith this will happen and many new eyes and long term investors will join.
THANK YOU SOLDIERS!
Have you ever spoken to Art? You are correct...he is a simple man and razor focused on drugs and science to push forward....he does not get emotional about penny traders and short groups. If you believe you invest....if you want to chance being left in the dust or on the other side...good luck.
Happy Memorial Day! Weekend
I’ll take over your 500K-1million
IMO - the fact they are giving up first rights on other potentially huge markets, I’d say they get more...much much much more.
OM will be huge. I bet that comes first and blind sides you and your crew.