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YEP! You look away for a few minutes eom
JUST A MILK MACHNE FOR BUMKO AND DR DEATH -- $600K PLUS PER YR FOR THE DUO SALARY THAT MADE THIS A R &D DISASTER SINK HOLE
BUMKA GETS A $1000 A DAY (including weekends) FOR DOING soft piece on access wire or BS lunch with ted O --I ' LL TAKE THE JOB FOR HALF THAT AND SO WILL MANY OTHERS
its a green day -- i am happy for that glta
just look. at the numbers not my post-- but something is wrong here
BUNKA AND TED O RIP OFF AND MAYBE YOU TOO == POS
WTF ????
Thanks Shawking - eom
Thanks Shawking - eom
THANK YOU everyone for your posts--GLTA
I need a lot more than $2.50 a share to just break even --
remains to be seen-- I will loose or make some money? GLTA
yep get my money back would be great
THANK YOU EOM
thank you EOM
if there was a deal with a significant partner -- the pps would rocket -- as those in the know would be buying big time... BUNKO =s BS and not success
No blame for honest underpaid ($30k/mo plus perks/options etc. ) CEO BUNKO and his side kick $300k plus a year with more options this past week Dr John -- LOL
more shares for DR death??
THANK YOU ALL FOR YOUR RECENT POSTS EOM
Bunko is doing a great job running this company -- into the ground
He. gets $30k a month, perks and I am sure free shares and or options -- and for what??
another R/S from thatPOS CEO
1.
To approve filing of a Certificate of Change to the Company's Amended and Restated Articles of Incorporation, to affect a reverse stock split of its common stock by a ratio of not less than 2 current shares for 1 post reverse stock split share and not more than 12 current shares for 1 post reverse stock split share ("Reverse Stock Split") at any time prior to 05/31/24, with the Board having the discretion as to whether or not the Reverse Stock Split is to be effected, and with the exact ratio of any Reverse Stock Split. More Details
Board Recommendation:
For
For
Against
Abstain
To approve the adjournment of the Meeting to a later date or dates, if necessary or appropriate, to solicit additional proxies if there is insufficient votes in favour of Proposal No. 1 or to establish quorum. More Details
Board Recommendation:For
2.
To approve the adjournment of the Meeting to a later date or dates, if necessary or appropriate, to solicit additional proxies if there is insufficient votes in favour of Proposal No. 1 or to establish quorum. More Details
Board Recommendation:
For
For
Against
Abstain
Unfortunately, Bunko has no reason to lower his salary with the board in his pocket and mgt gifting themselves shares/investors money as they see fit. I do hope he messes something up enough to end up in prison making new friends.
Bunko and Ted are both a POS -- and yes we got f d by them --
he has to answer questions honestly for a secured loan, dilution -- he just awards himself more shares while getting $30k a month salary plus perks/ percentage of a sale etc. for BS ing investors imho
definitely a "Hail Mary" play for me....but getting my mind adjusted to tax loss glta
FYI. Lexaria's Human Clinical Nicotine Study Completes Dosing as Planned
9:05 am ET May 8, 2023 (Accesswire) Print
KELOWNA, BC / ACCESSWIRE / May 8, 2023 / Lexaria Bioscience Corp. (Nasdaq:LEXX)(Nasdaq:LEXXW) (the "Company" or "Lexaria"), a global innovator in drug delivery platforms announces that dosing of the targeted 36 subjects in its human clinical oral nicotine study NIC-H22-1 has been completed.
Human study NIC-H22-1 represents the culmination of several years of work performed by Lexaria on oral nicotine formulations as an alternative to vaping or smoking and may entice the more rapid commercial adoption and distribution of Lexaria's patented DehydraTECH absorption technology in an industry sorely lacking in oral uptake and performance optimizing innovation for many years.
The dangers of cigarette smoking are well known and result in the death of 7 million people per year. Nicotine vaping was originally hoped to help wean people off cigarette use but has had mixed results in doing so, and vaping has also been associated with serious health risks. Nicotine vaping is becoming increasingly controversial and is severely limited in certain countries and was, for instance, just banned in Australia and is either banned or restricted in many other countries. By comparison, Lexaria's DehydraTECH-nicotine is already patent granted for oral nicotine delivery in Australia and pending in numerous other countries. The white pouch category, as tested in study NIC-H22-1, is one of the fastest growing, tobacco-free alternatives to smoking and vaping.
Lexaria's DehydraTECH-powered purified nicotine white pouch formulation contains no tobacco. DehydraTECH-nicotine has already shown in multiple sets of animal testing that it can be up to 10-times to 20-times faster and able to deliver up to 10-fold higher levels of nicotine into blood plasma from oral absorption than concentration matched controls. If the findings from study NIC-H22-1 also show similar improved performance, this could facilitate a more satisfying oral nicotine experience than any of the leading brands sold around the world today which all rely on outdated formulation technology. Speed of onset is of vital importance to nicotine users and Lexaria's DehydraTECH-nicotine has demonstrated superiority in this regard.
Lexaria Bioscience Corp., Monday, May 8, 2023, Press release picture
Nicotine Plasma Levels (ng/mL) - DehydraTECH vs. Control From Lexaria's Earlier Animal Study
The oral nicotine pouch category is of intense interest to Lexaria and the nicotine products industry, and its growth is due in part to its reduced risk health outcomes as noted by the Food and Drug Administration ("FDA"). This delivery method, in the white pouch format specifically, which avoids harmful lung outcomes experienced by smokers or vapers, involves absorption primarily through the buccal and sublingual tissues of the mouth, of purified nicotine that has been separated from most other harmful compounds in the tobacco leaf. The global market for the oral nicotine pouch category was US$2.33 billion in 2020 and is growing at a rapid CAGR of 30.7% and is expected to reach $21.84 billion in 2027.
About Study NIC-H22-1.
Study NIC-H22-1 is a human pharmacokinetic randomized, double blinded, cross-over study conducted in a minimum of 36 human volunteers that are current cigarette smokers, wherein each person visited the laboratory to be dosed three times over several weeks. During each visit only one oral nicotine pouch was administered and evaluated: either DehydraTECH-nicotine; On! brand manufactured by Altria; or Zyn brand manufactured by Swedish Match. While 36 people have to date completed their dosing, Lexaria expects a small number of additional person(s) who were over enrolled into the study to also complete dosing in the immediate future.
The primary study objectives are to determine the quantity of nicotine in blood at various time points and vital-sign data collection including blood pressure, heart rate and respiratory rate. Subjective evaluations related to throat burn, user experience, gastrointestinal experience and more are also being conducted.
The study is fully funded from internal company resources. Sample and data analysis is already underway and will be reported upon as soon as possible and Lexaria will provide further updates and any relevant material findings in due course from this study as they become available.
About Lexaria Bioscience Corp.
Lexaria Bioscience Corp.'s patented drug delivery technology, DehydraTECHâ„¢, improves the way active pharmaceutical ingredients (APIs) enter the bloodstream through oral delivery. Since 2016, DehydraTECH has repeatedly demonstrated the ability to increase bio-absorption with cannabinoids, antiviral drugs, PDE5 inhibitors and more. DehydraTECH has also evidenced an ability to deliver some drugs more effectively across the blood brain barrier. Lexaria operates a licensed in-house research laboratory and holds a robust intellectual property portfolio with 30 patents granted and many patents pending worldwide. For more information, please visit www.lexariabioscience.com.
CAUTION REGARDING FORWARD-LOOKING STATEMENTS
This press release includes forward-looking statements. Statements as such term is defined under applicable securities laws. These statements may be identified by words such as "anticipate," "if," "believe," "plan," "estimate," "expect," "intend," "may," "could," "should," "will," and other similar expressions. Such forward-looking statements in this press release include, but are not limited to, statements by the company relating the Company's ability to carry out research initiatives, receive regulatory approvals or grants or experience positive effects or results from any research or study. Such forward-looking statements are estimates reflecting the Company's best judgment based upon current information and involve a number of risks and uncertainties, and there can be no assurance that the Company will actually achieve the plans, intentions, or expectations disclosed in these forward-looking statements. As such, you should not place undue reliance on these forward-looking statements. Factors which could cause actual results to differ materially from those estimated by the Company include, but are not limited to, government regulation and regulatory approvals, managing and maintaining growth, the effect of adverse publicity, litigation, competition, scientific discovery, the patent application and approval process, potential adverse effects arising from the testing or use of products utilizing the DehydraTECH technology, the Company's ability to maintain existing collaborations and realize the benefits thereof, delays or cancellations of planned R&D that could occur related to pandemics or for other reasons, and other factors which may be identified from time to time in the Company's public announcements and periodic filings with the US Securities and Exchange Commission on EDGAR. The Company provides links to third-party websites only as a courtesy to readers and disclaims any responsibility for the thoroughness, accuracy or timeliness of information at third-party websites. There is no assurance that any of Lexaria's postulated uses, benefits, or advantages for the patented and patent-pending technology will in fact be realized in any manner or in any part. No statement herein has been evaluated by the Food and Drug Administration (FDA). Lexaria-associated products are not intended to diagnose, treat, cure or prevent any disease. Any forward-looking statements contained in this release speak only as of the date hereof, and the Company expressly disclaims any obligation to update any forward-looking statements or links to third-party websites contained herein, whether as a result of any new information, future events, changed circumstances or otherwise, except as otherwise required by law.
INVESTOR CONTACT:
George Jurcic - Head of Investor Relations
ir@lexariabioscience.com
Phone: 250-765-6424, ext 202
SOURCE: Lexaria Bioscience Corp.
Bunko had a guy from Maxim group from Long Island, NY call me about investing with them. Said bunko referred him as I was a Lexxy investor. ?? Like I would want to hear about anything Bunko is associated with.
I am done - but will not sell for a few dollars at this point. Miracle if I get any of my money back. The miracle (IF it happens ) will be for pennies on the dollar. Bunko is a POS and I got taken. Perhaps the SEC will find something wrong with Bunko's guidance/dealings and burn him -- he deserves to fry.
overpaid underperform -- great ride for bunka and dr j -- not so good for investors
thank you but really sick of years of Ted O and the reality of pps today
BUNKA IS A SELF SERVING POS -- DEALS -- RAISING FUNDS ALL BS... REPRICING STOCK OPTIONS? ...THIS COMPANY MAY ( MIRACLE) DO WELL FOR PRESENT AND FURURE INVESTORS -- FOR OLD INVESTORS YOU/I AM/ARE F D FOR BELIEVING HIM . STUPID INVESTMENT ON MY PART... WRITTEN OFF .....WILL HURT ME BUT NOT KILL ME. MY SINCEREST BEST WISHES FOR ANYONE WHO HAD ANY FAITH IN BUNKA... ALL IMHO
Thanks Shawking -- eom
Yep -- no repricing. of course they will issue more shares to themselves and the bd. WOW did I ever F-up buying this stock. glta
this bd shows the pps at 1.69... I guess Bunko is offering a big discount and significant dilution. -- oh well glta
hope you are well. Another raise - no big surprise. If I get my money back that would be great. So I am hanging in there - in too deep to walk away at this point. gltu
pps today a pleasant surprise - maybe there is a good reason?
ty looks like nothing new - i will keep on waiting glta
Mansax-- they are putting small pieces of bait on a lot of hooks (DR Death spending lots of cash on rat studies). Bunka is preparing a library of studies to impress big fish/pharma -- instead of doing one or two things well -- they are doing many studies that no one gives a "rats a##" about in big fish/pharma land. Unfortunately, comp for bunko and dr death $600k plus -- they get paid for effort/failure and not results. If I get my money back -- it would be a miracle.
NEWS_Lexaria's DehydraTECH-CBD Diabetes Study Demonstrates Weight Loss, Improved Triglyceride and Cholesterol Levels
8:45 am ET March 2, 2023 (Accesswire) Print
KELOWNA, BC / ACCESSWIRE / March 2, 2023 / Lexaria Bioscience Corp. (Nasdaq:LEXX) (Nasdaq:LEXXW) (the "Company" or "Lexaria"), a global innovator in drug delivery platforms announces that its diabetes animal model study DIAB-A22-1 has completed and produced at least three positive outcomes including weight loss in obese diabetic-conditioned animals, together with improved triglyceride and cholesterol levels.
REDUCED BODY WEIGHT
Beginning just four days after the start of dosing with DehydraTECH-CBD, the obese rats began to lose weight. The weight loss was maximized nine days after dosing and maintained throughout the 8-week study duration. This apparent trend demonstrated roughly a 7% loss of body weight throughout the course of treatment at both DehydraTECH-CBD doses studied (30 mg/Kg and 100 mg/Kg). Only the DehydraTECH-CBD-dosed animals weighed less at the end of the study than at the beginning, whereas the weight of the untreated obese animals trended upwards throughout the study. The lean untreated animals gained the most weight of all to actually become obese by the end of the study.
Lexaria Bioscience Corp., Thursday, March 2, 2023, Press release picture
Furthermore, in the DehydraTECH-CBD treated rats the weight loss trend observed did not appear to be a result of lower levels of food or water intake. Food and water intake was comparable in both the treated and untreated obese animal groups suggesting that the weight loss was more so related to enhanced metabolic function.
According to the National Institute for Health, obesity or being overweight is the leading cause of diabetes.
ACTIVITY LEVELS
Obesity is often accompanied by reduced activity levels, which were measured in this study via locomotor activity, the distance the animals travelled in open field observations. Interestingly, the lower dose of DehydraTECH-CBD resulted in a statistically significant improvement in locomotor activity compared to the untreated obese control rats (*p<0.05), whereas there was no significant difference accordingly evidenced at the higher dose. As expected, activity levels for all obese rats were significantly lower than the lean control rats (#p<0.05), although only the lower dose DehydraTECH-CBD treated rats approached the activity levels of the lean rats. Previous research has suggested that CBD may enhance motor activity through its action upon the serotonin 5-HT1A receptor.
Lexaria Bioscience Corp., Thursday, March 2, 2023, Press release picture
Additional investigation will be required to learn what an optimum DehydraTECH-CBD dose related to both weight loss and increased physical activity might be, given the fact that the higher dose studied may have elicited sedative-like effects of CBD triggering hypolocomotion which others have also observed upon high systemic exposure.
TRIGLYCERIDE AND CHOLESTEROL LEVELS
Higher triglyceride levels in the blood can be an indication of the onset of diabetes. One of the best ways to manage triglyceride levels is to lose weight. In study DIAB-A22-1, the animals dosed with DehydraTECH-CBD showed statistically significant reductions in triglyceride levels from day 35 onwards compared to the obese animals not dosed with DehydraTECH-CBD. Once again, the lower dose of 30 mg/Kg of DehydraTECH-CBD outperformed the higher dose of 100mg/kg. By the end of the study the triglyceride levels in the animals receiving 30 mg/Kg of DehydraTECH-CBD was over 25% lower than that of the untreated obese animals (*p=0.007).
Lexaria Bioscience Corp., Thursday, March 2, 2023, Press release picture
Lexaria Bioscience Corp., Thursday, March 2, 2023, Press release picture
Cholesterol levels in the animals receiving DehydraTECH-CBD were also higher. There are two types of cholesterol - HDL and LDL - where HDL cholesterol is generally considered "good" and is desired and LDL cholesterol is generally considered "bad", although some studies are beginning to question whether this is true. Again, the lower dose of 30 mg/Kg appeared to outperform the higher 100 mg/Kg dose of DehydraTECH-CBD, with a trend toward increased HDL good cholesterol but with no significant effect upon LDL bad cholesterol levels compared to the untreated obese animals. The 100 mg/Kg dosed animals demonstrated increases in both desired HDL and the undesired LDL levels, with significance relative to the untreated obese animals in the latter instance (*p<0.05). The findings with the lower dose therefore appeared to support improved physiological function relative to the diabetic state.
According to the American Diabetes Association, CBD is not thought to directly reduce blood glucose levels as previous clinical studies have discovered, nor was any significant effect from DehydraTECH-CBD dosing on blood glucose measured or expected in this study.
SUMMARY
Animal study DIAB-A22-1 evidenced, at times, dramatic changes in body weight, general activity, and triglyceride and cholesterol levels associated with administration of DehydraTECH-CBD. These findings are well aligned with other study work in animals that points to the known anti-inflammatory and antioxidant properties of CBD functioning to lessen some of the essential pathophysiological factors associated with diabetes. Lexaria is pleased that relatively low doses of DehydraTECH-CBD seem to be supportive of real improvements in day-to-day health of the lab animals and the Company is very encouraged by the positive findings from its first study of DehydraTECH-CBD in this diabetes animal model, indicating many prospective benefits worthy of further investigation together, perhaps, with other drugs that further help to control glucose levels directly.
ABOUT THE STUDY
Study DIAB-A22-1 administered select Lexaria "DehydraTECH-CBD 2.0" formulations at doses of either 30 mg/Kg or 100 mg/Kg of body weight in a total of 32 male Zucker "ZDF" rats - 24 obese and 8 lean. The study length was doubled from four weeks of dosing to eight weeks of dosing, after initial positive early responses were witnessed. Treatment was well tolerated throughout the course of dosing with no serious health concerns observed in the animals that received DehydraTECH-CBD. The health of some of the obese animals declined after the study had concluded as might be expected, likely as a result of the advanced pathology and possible ketoacidosis from the prolonged diabetic condition of these disease-model animals. Study DIAB-A22-1 was undertaken by a leading, third-party testing laboratory located in Canada.
ABOUT THE DIABETES MARKET OPPORTUNITY
Diabetes is a disease whereby the body does not produce sufficient insulin, leading to higher than normal levels of sugars in the blood. Risks of kidney disease, vision loss, heart and cardiovascular disease and more are greatly enhanced by individuals with diabetes. Because diabetes is often closely connected to obesity, it is a chronic and growing problem around much of the world.
People with type-2 diabetes can often control the disease through lifestyle changes and/or taking certain diabetes medications, whereas those with type-1 diabetes are required to add insulin to their body through syringes, insulin pumps, or other similar devices. Thus the treatment of diabetes includes devices, drugs, and lifestyle alteration. The global diabetes devices market is estimated at $26.7 billion in 2021. The global diabetes drug market is estimated at $63.1 billion in 2021. Due to the pain and unpleasantness of injections, many diabetes sufferers prefer to treat their condition with drugs rather than devices, if they have the choice. More than 1.9 billion people were overweight in 2016, and due to the growth in obesity, which has nearly tripled from 1975 to 2016, the number of people experiencing diabetes continues to grow.
About Lexaria Bioscience Corp.
Lexaria Bioscience Corp.'s patented drug delivery technology, DehydraTECHâ„¢, improves the way active pharmaceutical ingredients (APIs) enter the bloodstream through oral delivery. Since 2016, DehydraTECH has repeatedly demonstrated the ability to increase bio-absorption with cannabinoids, antiviral drugs, PDE5 inhibitors and more. DehydraTECH has also evidenced an ability to deliver some drugs more effectively across the blood brain barrier. Lexaria operates a licensed in-house research laboratory and holds a robust intellectual property portfolio with 28 patents granted and many patents pending worldwide. For more information, please visit www.lexariabioscience.com.
CAUTION REGARDING FORWARD-LOOKING STATEMENTS
This press release includes forward-looking statements. Statements as such term is defined under applicable securities laws. These statements may be identified by words such as "anticipate," "if," "believe," "plan," "estimate," "expect," "intend," "may," "could," "should," "will," and other similar expressions. Such forward-looking statements in this press release include, but are not limited to, statements by the company relating the Company's ability to carry out research initiatives, receive regulatory approvals or grants or experience positive effects or results from any research or study. Such forward-looking statements are estimates reflecting the Company's best judgment based upon current information and involve a number of risks and uncertainties, and there can be no assurance that the Company will actually achieve the plans, intentions, or expectations disclosed in these forward-looking statements. As such, you should not place undue reliance on these forward-looking statements. Factors which could cause actual results to differ materially from those estimated by the Company include, but are not limited to, government regulation and regulatory approvals, managing and maintaining growth, the effect of adverse publicity, litigation, competition, scientific discovery, the patent application and approval process, potential adverse effects arising from the testing or use of products utilizing the DehydraTECH technology, the Company's ability to maintain existing collaborations and realize the benefits thereof, delays or cancellations of planned R&D that could occur related to pandemics or for other reasons, and other factors which may be identified from time to time in the Company's public announcements and periodic filings with the US Securities and Exchange Commission on EDGAR. The Company provides links to third-party websites only as a courtesy to readers and disclaims any responsibility for the thoroughness, accuracy or timeliness of information at third-party websites. There is no assurance that any of Lexaria's postulated uses, benefits, or advantages for the patented and patent-pending technology will in fact be realized in any manner or in any part. No statement herein has been evaluated by the Food and Drug Administration (FDA). Lexaria-associated products are not intended to diagnose, treat, cure or prevent any disease. Any forward-looking statements contained in this release speak only as of the date hereof, and the Company expressly disclaims any obligation to update any forward-looking statements or links to third-party websites contained herein, whether as a result of any new information, future events, changed circumstances or otherwise, except as otherwise required by law.
INVESTOR CONTACT:
George Jurcic - Head of Investor Relations
ir@lexariabioscience.com
Phone: 250-765-6424, ext 202
SOURCE: Lexaria Bioscience Corp.