Trading around a core position would have provided gains thus far for sure, no argument about that.

It’s a skill I have not fully developed despite all the years I’ve been investing in stocks. Recently this has cost me big time letting a couple of large positions go from being up triple my basis to losses! These are large cap companies that have been leaders, however the market has been a rotating haircut machine lately.

Long term though, it’s been my core buy and hold investments that have provided the largest value creation for me. Just 4 or 5 stocks over 20-35 years, reinvesting dividends, has grown to be 66-75% of my total portfolio of over 100 positions.

Nwbo has the potential to be one of my largest losses or by very far the best once in a lifetime investment!

My latest refusal to sell even a small number of nwbo shares, in fact buying more, in the face of my spouse pleading for me to sell half, has me at a distinct disadvantage in any difference of opinion: you’re the one that didn’t listen to me when I wanted you to sell…. And all I can say is, but the data is great! And we’ll see soon!

At least I was able to get back into the house by asserting that the sp drop is temporary and due to unethical shorts and market players, and that their best efforts will not succeed in keeping the lid on the first meaningful advancement in GBM treatment and survival in decades!

I’ve picked up some more shares since the NYAS presentation results significantly derisked the investment.

That’s a rather nice park bench!

Uniform lovely mahogany red stained wood throughout, with no signs of cracks or splintering.

The metal structure is a wonderfully artistic curved cast iron with a thick and lustrous coating of paint or enamel, possibly baked on.

The stone block ground pad provides a solid foundation that avoids mud, deep puddles, and unwanted vegetation growth that would harbor pests and ticks, while ensuring the bench will not tilt or wobble.

Yes, solid American design and quality!

I trust the park is in a prime neighborhood; location, location, location!!!

There’s a special place in ____ for the ilk who like AF purposely misrepresent the facts and fabricate misinformation against life extending and saving treatment for a disease that otherwise takes people quickly and spares no one.

Especially when attacking a treatment that causes no harm and suffering from the treatment.

What treatment would you chose should you suffer the misfortune??? Honestly!

You have a valid point about not counting your RA chickens before they hatch in environments where people can be influenced by pressure “points.”

However the overall backdrop of a disease that has a worst prognosis that spares virtually no one, with < 5% 5 year OS, and a treatment is available that causes no harm while building a growing group of long term survivors, what kind of conscience would it take to deny that treatment?

Also, the queue for compassionate care treatment would keep growing imo, and the outcry from families who want the treatment for their loved ones would grow as well!

There is also a check & balance among the RAs such that if the UK approves, the fda would be scrutinized for a different decision.

And the rest of the world would not be far behind in adopting, and some outright claiming the innovation as their own, as the survival outcomes continue to accumulate.

Respectfully, this stock isn’t damaged.

It’s never been better, actually, if you consider the treatment and it’s chances of being approved and all the positive catalysts coming soon.

Yes, I did say soon!

The stock price action is more a result of anticipation and obvious lying, distorting, disingenuous, factions and it’s very obvious.

The current stock price is holding and FUD will continue to be shown to be baseless as indisputable results continue to be expanded on.

Make no mistake, the TLD results are positive and if anyone I know should have the unfortunate diagnosis of GBM I would want them to be treated with DCVax.

What treatment would you chose?

Reality check, it beat SOC, shorty, and the dots will be connected. Dots right!

Given the tragedy of his son’s passing due to GBM, I would think he would be particularly interested in the first treatment improvement in 15-27 years that in effect cures some, extends survival of many, and looks to be the key portion of even more successful treatments!!!

Now that’s a recommendation I can apply in the real world!

I betcha “Hey Elizabeth Hurley!” Would be effective as well

Now wait a minute Grasshopper!

I’m in their age group and still have all my moves and karate kicks, except I pull muscles and get muscle cramps in places I didn’t know I even have muscles

On average I’d give them (me) at least another 20 years before requiring walkers.

What’s that you say sonny?

Results are such that anyone with GBM will want and should get dcvaxL because there isn’t a better treatment, and that is valuable.

Combo treatments are a no brainer and further expand use of dcvaxL

Remember GBM is about as tough a cancer as there is and dcvax showed improved outcomes and greater chance of long term survival, so how well might you guess dcvax will work against other cancers that don’t have a blood-brain barrier boundary?

PM, nice to hear you’re well, and as for your new digs, actually not bad!

It lacks the style and grace of a nicely made park bench, however there’s a lot to be said for the rain and wind protection, and offers a degree of privacy to boot.

I may be taking you up on your invitation, and I’ve watched a lot of survival shows and learned survival skills. Don’t worry, I would come Afraid, definitely not Naked, we’ve all been through enough ugliness today!

Thanks! It’s reassuring to hear others continuing to invest.

https://www.tastingtable.com/855789/your-instant-ramen-will-taste-better-with-one-simple-addition/

After today I figure it’s back to Ramen!

That magnum of champagne I planned to pop, not only didn’t I pop it but my spouse chased me out of the house trying to crack me with it.

I took shelter under the nearest park bench and stayed there until I could no longer hear the bloodcurdling screams of I told you to sell but you never listen to me!

Oh oh, gotta run and hide!

Call me a glutton for punishment however I bought more at around 0.77 on the bounce from the 0.40s.

So very true!

So she’s probably less than 60, which is the new 40

Besides, age is just a number, and the voice in our heads never gets old, you ever notice that? Mine is forever about 19-21, how about y’all?

Any takers for a Yugo?

Geee if LL is talked about as old then I’m ancient.

Old? She’s not old.

I mean, we can’t all be millennials, but we got a lot of good miles to go! And if tomorrow morning goes splendidly I plan on self lubricating with low viscosity bubbly!

In the off chance things don’t go well I’ll be the one being kicked to the curb

So let’s see, the fact that international travel is requiring Covid testing, and this latest variant spreads extremely easily, creates an unbelievable situation?

Unfortunate, yes, because LL deserves the spotlight.

Unbelievable, no. If you watch live television these days, show hosts and participants are contracting Covid.

A number of our family members are testing positive for Covid.

I do wonder what LL was doing in the UK just before NYAS?

Not my business though.

I’m wondering if she’ll participate remotely along with Dr Mulholland?

Just watched American Idol, and several contestants got Covid, and depending on the individual they either used the recorded rehearsal or they performed from their hotel room.

It’s the next best thing to being in person.

I think the Friday close was repeated today. The sp was mainly up 2 or 3 cents, and it looked to me that the price was knocked down right at the close again. Maybe I’m imagining but it’s as if there was no way the sp was going to be allowed to close up today, and Friday.

I’m still awake too

Sometimes it’s not the size but how you use it

Seriously, I wouldn’t exclude NEJM, however I wouldn’t exclude other fine journals of medicine and especially, oncology.

NYAS is not chopped liver of a venue, it’s prestigious, and ASCO will still be there in less than a month and given the press coverage to be expected from May 10th until ASCO I think all those oncologists will be quite interested to engage and learn more about DCVax and the phase 3 results.

That’s an individual opinion and assertion, which you’re entitled to, as each of us are entitled to draw our own conclusions.

Objectively though, there sure seems to be a lot of statements, PRs, and other indications that the phase 3 trial data will be shared Tuesday.

We may get further information tomorrow and certainly Tuesday morning, so we’ll know soon enough.

Based on the title of Dr Liau’s presentation, I’d say exceedingly unlikely

(approaching zero in the limit as an infinitesimally small delta approaches zero)

I unless the NYAS and Dr Liau just toss around semi random unreliable information on matters of the greatest importance!!!

We will know in less than 48 hours and maybe within 24 hours, finally!

I’m probably going to have trouble sleeping from anticipation and waking up to check the time and for PR/updates.

Kinda childish on my part but at my age a little childish behavior might be a good thing!

LP and LL and teams got to the goal line against all manner of defense trying to shut them down, including plenty of unsportsmanlike behavior, so I’m just going to trust them to score the win as they know best.

If there happens to be some shorts squeezed then dems the breaks!!!!

Let’s explore the logic further:

There already are patents related to DCVAX, and DCVAX in combination with other treatments such as Keytruda, Opdivo, etc.

NWBO and associates can address the potentially broad range of (non-combo treatment) solid tumors without a buyout or teaming with a BP, however might not be as prepared and equipped for full marketing effort(s) and could take awhile to raise funding

Licensing and/partnership/teaming with multiple BPs for combo treatments certainly doable and probably a given. Would support the quickest, broadest, most affordable, route to go up learning curve and revenue/sales growth

If the science is validated for many indications and combinations, the potential value creation is humongous imo

You’re a humanitarian!

Makes me wonder how many other unsung heroes are out there quietly doing their best for mankind!

This may be my last post until after midnight since I must be at or close to the board limit for unpaid posters already.

It would have been a much needed shot in the arm (pun intended) for the ARK funds, and not too late imo.

Yes indeed, so you must act responsively when on the bench, after all if a little rumble of passed gas might cause a thunderstorm in Beijing, imagine the potential impact on Hong Kong if you let one rip

I think it’s called the butterfly bench effect!

It could be as simple as there may be a simultaneous release of a Short PR stating the TLD in the form of the endpoints were met. You can find examples and they are very brief statements.

That would take care of any concerns about equal access to TLD.

Dr Liau could share the same and more in her presentation, where one slide could easily cover TLD.

No worries

Yea, that’s it!

They’ve adapted Tesla cars to host FlaskWorks devices so DC vaccines are produced as an added value feature! NOT

Just joking !!!

Don’t have to cover everything in detail just summarize the trial and analyzed data to show “is we is or is we ain’t “ efficacious and meeting the trial endpoints.

Paper presumably details everything and there will be other conferences and events to follow if successful.

ASCO less than a month later, plus others.

If news is good as we expect the news media will cover it. They did the last time for blinded interim info.

I guess it never gets old for someone to sign up for events as Donald Duck, and other assorted characters.

Would be surreal if Elon Musk really showed up at NYAS as a buyer/investor, however I think he’s got plenty on his plate already!

I hope to pop the cork on the bubbly I’ve been keeping for this such occasion!

I hear ya 100% !

I was very tempted to go in person since I’m about an hour drive from Park Avenue, however except for the many trips for medical reasons I avoid driving into midtown Manhattan these days.

Oh well, I wasn’t aware there was a registration cutoff, and I will be following this board continuously Tuesday morning. I alerted my wife that I will not be going or doing anything else Tuesday.

She’s onboard now that I’ve convinced her of the imminent good news, except she’s still urging me to sell if the stock price goes up, and I’m still reminding I didn’t go through thick and thin for about 13 years to not stick around as much as I could for the growth to come.

God help me if things go in the wrong direction ?

Better yet, if you can’t beat’em, join’em, and buy some nwbo shares if they don’t gap too far up Monday.

What I clearly saw and heard was Dr C reply that the trial data is being presented on May 10th in New York, and he clearly pulled up and read verbatim the PR to ensure he provided the correct detail.

No doubt in my mind this is what’s in the video!

Yes, and looking at the structure of the combo treatment trial of dcvax + keytruda + Revimmune component, dcvax is given in both combo and control groups, thereby treating dcvax like a SOC !

It is my opinion that Dr Liau’s UCLA team knows DCVax L is effectively the treatment to beat for the combo trial, and structured the trial accordingly even though DCVax L hasn’t been approved yet!