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OT: just a simple yes/no question. Do you believe that climate change is a real and if so, that C02 emissions are a large cause?
Full disclosure: for me, it's "yes"
A mess is right! Nothing like watching 2 losers kick each other when they're down.
Lol. "Anything the government wants to do there's a better way with private industry"
Does that include bail-outs? Wow. I can't believe the extent to which we've been conditioned to not only hate government but also love multi-national corporates.
MTNB out with positive news/small sample results:
http://www.matinasbiopharma.com/media/press-releases/detail/293/matinas-biopharma-announces-interim-data-from-nih-conducted
“We are incredibly pleased with the interim safety and efficacy results of this Phase 2a study of MAT2203. While we understand the results are representative of just two patients, these patients are difficult to treat because of their severe underlying immunocompromising condition. With the statistical success hurdle that was prospectively set at a 20% patient-response probability, seeing a clinical response in two out of two patients brings us very close to the 3 out of 16 clinical responders required for the study to meet its primary endpoint, “ said Roelof Rongen, Chief Executive Officer.
As expected, oral thrush promptly returned after stopping treatment with MAT2203. Therefore, Matinas’ preliminary clinical data indicate that MAT2203 is promising as an oral systemically-absorbed broad-based antifungal without the toxicity of parenteral amphotericin B.
CC Monday, June 5, 2017 at 8:30 a.m. ET
Volquez was a monster in the 2015 playoffs. Definitely a guy who can flash outstanding stuff, especially when the spotlights are hot and the cameras are rolling. Shutting down the Snakes line-up is a real accomplishment.
Brewers were 3 outs away from pinning an "L" on Kershaw today. This team reminds me of the 2015 Cubs: much better than expected much earlier than expected. Hard to see it lasting all season though with the rotation they currently trot out there....how many quality starts can you realistically expect from Matt Garza?
However the season ends, you gotta love David Stearns' chances for GM of the year. He's done almost everything right...except not jettisoning Braun last year when he had some value.
In 2008 the Brewers traded for and rode CC Sabathia, who ruled the league and drove the Crew to a post season bid. Love to see Stearns learn from that deal and swing something similar this year.
Anyone else like to see the Cubs miss out on the playoffs this year?
You're too negative on the Metties. Bright side: grandy over .200!!!!
Couldn't help but buy a slug at 1.57 today. Never thought it would sink this low again but I gotta think that the current PPS is within 15% of rock bottom.
You win the game and still complain. Hard to please a NY fan, wow. Walker is starting to heat up, Harvey and Wheeler look decent, Cespedes is hitting balls again... and you're only 7 back of DC. Hopefully this isn't the Mets peaking early!
Look on the bright side: Grandy's got the BA over .170 now!
The Rangers are looking really good these days. Gotta love the direction they're heading after 40 games...especially after the first 25.
Yu looks like he's fully back...now just gotta get Hamels healthy and upgrade bullpen a bit. Maybe make a few more roster moves late in the season and you should be all set to lose the wild card game!
Just ask A-roid!
Nah , his publishers are just too lazy to leave their midrown offices.
Ah, the ol' sell low buy high contrarian strategy! Might be time for Dusty to start getting the rotation in order for the post season. What a POS division this season.
Coincidence or what??!!
Believe or not, monument park in yankee stadium isn't every player or fans' ambition. Now up the road at Cooperstown, that's a different story.....and there are some players there who didn't suit up in the bronx....just a few??
And who knows? Maybe if he can stay off the dl they'll paint Cano's mug and jersey number on a boxcar that frequents the tracks in the Mariner's outfield...
I'd have happily left town for half of that 60 million!
How sweep it is! Lovin that Mets bullpen! De Grom wasn't great but he certainly deserved better. Maybe next time
Lol.
Well I'd expect better things from the Mets tomorrow when de Grom saddles up...which is why winning the first 2 is so crucial.
How about those Brewers! Some real, real sweet box scores in Miller Park vs the Red Sox and Mets this past week.
I only wish they had traded Braun last year...or in the off season when he had some value. IMO, The team has no room for him as they rebuild and could really benefit from a couple of pitching prospects while shedding the remaining large salary. DL time was inevitable for Braun this season and the front office should have moved him before it happened.
Tough break for mets familia again....if you need a closer, happy to let you take Neflati Feliz. Cheap.
Does PIOE qualify?
Losing Cespedes does indeed suck...on the other hand, the Mets were so close to a Carlos Gomez trade before dealing for Cespedes. Thor? Sure, great potential, but "ace" is a term reserved for a pitcher who has proven himself in that role over a few years minimum IMO. MLB has rosters full of players with great potential, but very few true aces and superstars. Like Thor. Harvey. Matz. Wheeler. (de Grom is a different story).
And for the position players, it's even more so case that you shouldn't count on something you've never really had, ie Duda, d'arnaud etc. For me a position player has to string together at least 3-4 consistently fine years before they should rated as anything more than a pipe dream. That's why it's hard for me to see the Mets injuries as all that extraordinary.
If you go into a 162 season with a large core of players who have flashed brilliance but not performed at a high level over longer stretches of time, you better have a solid plan B. Clearly the Mets don't.
Or hope that everything clicks, like it did in 2015 for the Mets. And counting on that to happen, given the history of injury with line up, is a lottery ticket.
The pain in Met land is just beginning. When this current squad falls hard, you tell me who is available to trade for high level prospects to kick in the rebuild: Duda? Walker? Grandy? Lol.
Brewers are looking pretty healthy so far, knock on wood. Maybe it's those young legs...or Braunie's supplements regime. Either way, it's an exciting line-up they trot out there. Thames has gotten the headlines, but Broxton has been fantastic lately, and if Villar can get it going, we could be looking at a trade deadline deal for a pitcher or 2 for a solid wildcard run. Bottom line for me is that watching young talent is much funner than enduring veteran mediocrity. Much cheaper too! If an Asdrubal injury is the difference between making the playoffs, your line-up has fundamental problems.
This article sheds some light on the injury issue:
https://fivethirtyeight.com/features/the-mets-arent-even-best-at-getting-injured/
Yup, but I hear Jason Bay is feeling pretty good too!
This time im going to win this installement. Because i have a startup billiondollar company in my portfolio.
Only 1? LOL
can a team, who is paying a player a lot of money, force the player to go for an MRI?
Good question. Wrong player, re, "a lot of money...."
http://www.nydailynews.com/sports/baseball/mets/mets-small-bringing-hammer-syndergaard-contract-article-1.2988869
hard to say for sure, but maybe $9,000 buys a bit of cooperation.
And if the Griffey dolls run out, there has to be a hefty stash of Chone Figgins bobbleheads laying around the clubhouse...
Martin wasn’t producing at even a below-average clip.
He was hitting .111 with a double, four steals and an anemic .172 on-base percentage and a .130 slugging percentage in 15 games.
These numbers could have been taken from a few dozen major leaguers earning better than 5 million a year (slightly more than the 4.85 mill Trader Jerry is paying Leonys this year):
Grandy, 17 million/Mets, now hitting .149
Joyce, 5 million/A's, now hitting .170
Bautista, 18 million/Jays, now hitting .132
But the all-time classic: Bobby Bo/1.19 million/Mets/ hasn't batted since 2001!!!
Well the Mets failed in that goal last year and probably will again thus year. Wright and Matz don't count IMO and any innings you can get from Harvey and Wheeler are a bonus. Dude's back is only slightly more reliable than Wright's.
It's still early, but IMO the Mets won't make the play-offs because ownership are cheap bastards, not because of injury.
So you buy today at $3.60 and sell pre-PDUFA in the mid 4's...that's a pretty decent return over 6 weeks.
No question about the incompetence of management here, but IMO it's still a decent run-up play.
ADMP on sale today. Again. The company just sold a bunch of commons for $3.50. Glad I waited to jump in here; this company has been repeatedly responsible for teaching me some hard and ugly lessons about bio-tech investing in the past, but with a PDUFA by June 4, there's more than enough time for the PPS to climb again IMO.
From the last CRL PR:
Because of the improvements that were made to the PFS in response to the FDA’s original CRL dated March 27, 2015, the FDA indicated that in order to support approval of the product, the Company must expand its human factors study (patient usability) and reliability study (product stress testing), both of which were part of the final PFS NDA. The Company believes that it can finalize the study protocols with the FDA and complete the additional testing within a relatively short period of time at an immaterial cost, and submit the data back to the FDA sometime in the second half of 2016. It should be noted that the Company has successfully completed the “volume delivery” issue that was associated with the initial CRL. The FDA has indicated that the NDA will remain open until these issues are resolved.
This is a PDUFA run-up play pitting what seems like a pretty straight forward response to the FDA CRL against ADMP management which instills little confidence in getting the job done.
https://ih.advfn.com/p.php?pid=nmona&article=74391541
Looks like the Mets have seen enough of Granderson for a while. Barring injury, it's hard to see where he fits in...unless Conforto performs as miserably as Grandy.
Ellsbury on the other hand has been contributing decently for the Yanks. Yes, it's early days, but....
Speaking of hot starts, how good is Thames looking in Milwaukee?
Make that 2-8 after another bullpen collapse. Any game that the Mariners get 5 innings out of Gallardo and he only gives up 4 earned is a game they gotta win, lol.
What an epic collapse tonight by the Rangers! Wow....nothing Beltre can do about that bullpen...
I think you're 1/2 right: starting pitching is more important than the pen in the regular season. Innings do indeed need to be eaten. My dad's favorite pitcher was Wilbur Wood, the White Sox knuckler, who often started both sides of a doubleheader. His best single season innings total was 376. Today, you'd be happy to get that single season innings total from 2 starters!
But come the playoffs, it's the exact opposite IMO. Think of those awesome Tigers rotations...Verlander, Scherzer, Price...and then they handed the ball over to that year's version of Byung Hyun Kim
Caveat: Unless you have a few Bumgarners.
Looks like Perez is the least of the worries in Arlington. Losing 3 in a row ain't the end of the world, but losing 3 in a row like this....that leaves a mark! In today's MLB, you don't win a skanky bullpen, regardless of the starting 5.
Rangers won a lot of close ones last year. Maybe they over-borrowed some good luck from the 2017 season....
BLRX
started a position here on the news that their recent offering (which drove the PPS down to this level) is complete and the underwriters bought up the whole tranche of additional shares:
https://ih.advfn.com/p.php?pid=nmona&article=74273623
Agreed. When .500 baseball is 6 games iaway after week 2, it's time to go fishing.
Zunino is certainly looking like Mr March again, albeit a small sample.
Brewers? Braunie 0-4 with a caught stealing. Gonna be a long season in beer town methinks....