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Created: 03/26/2013 03:17:42 PM - Followers: 102 - Board type: Free - Posts Today: 0




Bio-Path is engaged in the business of financing and commercializing novel cancer therapeutics acquired from MD Anderson Cancer Center. Their first Antisense drug BP-1001, known as Prexigebersen has completed a partial phase II combination trial (with LDAC). The interim results demonstrated 47% of the patients showed early anti-leukemic activity.


http://www.biopathholdings.com/wp-content/uploads/2018/04/BPTH_Interim_Phase_2_AML_Data_Release.pdf 

The Prexigebersen phase II trials for AML are located at MD Anderson, Weill Cornell Medical College Presbyterian Hospital, Baylor, New Jersey Hematology Oncology Associates, West Virginia University and University of Kansas.

Bio-Path Holdings is focused on antisense drugs which work at a cellular level to interrupt protein production by the diseased cell. The lead drug, Prexigebersen is targeting the Grb-2 protein. Bio Path Holdings' delivery system is a small molecule neutral liposome system. Through the phase 2 of the combination trial for Prexigebersen there has been absolutely no toxicity. The results of testing performed by Bio Path demonstrates an uptake of the drug at a cellular level. The pErk results demonstrate not only a 50+% knockdown of the target protein but shows the pathway was shut down validating the delivery system. The purpose of phase 2 will be to test the effectiveness of the drug. Interim results are positive.

A CML combination drug safety study with Sprycel (Dasatinib) for Prexigebersen has begun at MD Anderson.

Patent protection for manufacturing their neutral lipid delivery system has been granted.


http://www.biopathholdings.com

This link to the company website describes their delivery technology:


http://biopathholdings.com/technology/


The company was founded on the technology from M.D. Anderson Cancer Center at the University of Texas in Houston. M.D. Anderson is the largest insitutional shareholder. After raising additional funds the company has 2+ million in cash. BIO-PATH'S viability is in question due to a lack of funds.

 
Bio-Path Holdings does not manufacture their drugs but uses contractors, hence the need for partners.
 
BPTH is presently traded on the NASDAQ.

Here are links to articles on their drug technology:


http://www.abstractsonline.com/pp8/#!/4292/presentation/2610

http://www.biopathholdings.com/wp-content/uploads/2017/06/Published-Article-Evolution-of-Antisense-in-Oncology.pdf

http://www.biopathholdings.com/wp-content/uploads/2018/03/BPTH_Lancet_20180329.pdf


Stone Gate Capital "under valued"
https://finance.yahoo.com/news/stonegate-capital-partners-updates-coverage-213000664.html        
https://investorshub.advfn.com/75fb7cf5-a8b2-4eb3-b48e-3bb1403ff45a"="" rel="nofollow" target="_blank">; style="height:1.200000; width:234.840000">

Our press releases-See Links here
http://www.biopathholdings.com/press-release/


Bio-Path Holdings, Inc. Announces $18.5 Million Registered Direct Offering of Common Stock

 
 

 

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#6344
Anyway, pps has been climbing slowly & steadily cfoofme 07/09/2022 02:57:47 PM
#6343
Anyone here still holding BPTH? cfoofme 07/08/2022 07:30:11 PM
#6342
86,231 shares traded today. mik1234 10/22/2021 10:51:53 PM
#6341 BPTH $$$ INFINITI 08/30/2021 07:22:02 AM
#6340 BPTH mik1234 08/27/2021 02:46:29 PM
#6339 BPTH mik1234 08/26/2021 06:22:02 AM
#6338 kool i hope this start running fda clear Pt3 08/24/2021 04:11:29 PM
#6337 AH will be interesting not selling $$$$$ INFINITI 08/24/2021 03:32:55 PM
#6336 Nice INFINITI 08/24/2021 03:32:20 PM
#6335 Tomorrow this blows right by $9 Hercules1 08/24/2021 03:24:57 PM
#6334 kool got filled 6.32 ?? Pt3 08/24/2021 03:07:13 PM
#6333 Hasn’t been blood all day nothing but green $$$$$$ INFINITI 08/24/2021 03:05:52 PM
#6332 BLOOD EVRR Pt3 08/24/2021 01:49:08 PM
#6331 Cmon wtf INFINITI 08/24/2021 09:47:39 AM
#6330 Back to 52wk high let’s goooo$$$ INFINITI 08/24/2021 09:04:52 AM
#6329 Breaking out today ENJOY$$$$! INFINITI 08/24/2021 08:45:12 AM
#6328 Profitability Profit Margin 0.00% make it happen 08/24/2021 08:40:33 AM
#6327 Only phase 1. With 6 patients... Every old make it happen 08/24/2021 08:39:33 AM
#6326 Looks to run here got in $$$$ INFINITI 08/24/2021 07:52:31 AM
#6325 Hopefully we run tomorrow Warrens 04/21/2021 06:49:23 PM
#6324 Starting to look up here Warrens 04/20/2021 12:12:08 PM
#6323 * * $BPTH Video Chart 04-05-2021 * * ClayTrader 04/05/2021 04:49:28 PM
#6322 Analyst Actions: Roth Capital Starts Bio-Path Holdings at Dubster watching 03/11/2021 11:06:10 AM
#6321 Nice call, thanks! Iron heart 03/03/2021 03:58:27 AM
#6320 As I said on the 10th when it Stock_Barber 02/16/2021 06:49:20 PM
#6319 Turn out to be a pos pump and Roadtojourney 02/16/2021 04:53:18 PM
#6318 round trip is about complete Paullee 02/11/2021 11:05:43 AM
#6317 Pump and dump pos imo Roadtojourney 02/11/2021 10:50:00 AM
#6316 * * $BPTH Video Chart 02-10-2021 * * ClayTrader 02/10/2021 04:38:08 PM
#6315 Anyone know a broker that will let you Stock_Barber 02/10/2021 12:56:35 PM
#6314 $BPTH: it can hit $30 after hours today. Hercules1 02/10/2021 12:01:35 PM
#6313 Well, it's 3 of them..... took in some NicksterPDX 02/10/2021 10:57:50 AM
#6312 Thanks. Must be the best patent they have cfoofme 02/10/2021 09:54:51 AM
#6311 BPTH receives 3rd patent! NicksterPDX 02/10/2021 09:52:31 AM
#6310 Wow! Up over $10 with 23 mil vol. cfoofme 02/10/2021 09:50:55 AM
#6309 Looking for that power bounce today on BPTH jonny_red 01/06/2021 08:34:55 AM
#6308 The roof is about to blow off $BPTH jonny_red 01/05/2021 03:00:30 PM
#6307 Micro-Float...Bought some today 3.83...Glta zino 01/05/2021 11:08:38 AM
#6306 Awesome $ mik1234 12/09/2020 03:32:04 PM
#6305 Tomorrow will be INSANE sanderburwil 12/09/2020 03:15:34 PM
#6304 $BPTH to da moon $ mik1234 11/20/2020 01:57:56 PM
#6303 Great, they have started Phase 1 of BP blairsoldman 11/19/2020 11:39:16 AM
#6302 The proxy is out and includes a shareholder alex1940 11/06/2020 08:59:00 AM
#6301 Hey NicksterPDX, BPTH isn't going to FLY until SloDan 11/05/2020 05:12:59 PM
#6300 OK, this roller coaster ride is giving me NicksterPDX 10/29/2020 11:58:02 AM
#6299 * * $BPTH Video Chart 10-22-2020 * * ClayTrader 10/22/2020 06:12:28 PM
#6298 Breaking News: $BPTH 3 Penny Stocks To Watch whytestocks 10/22/2020 12:30:27 PM
#6297 Carl Icahn took stake! Biggeoff 10/22/2020 12:17:45 PM
#6296 Breaking News: $BPTH Bio-Path Receives Notice of Allowance whytestocks 10/22/2020 12:15:37 PM
#6295 Whoopy ding. Now if we could see blairsoldman 10/22/2020 10:31:47 AM
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