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There are plenty of others here to vigorously promote the science. I make my comments to remind people that this investment is fraught with risks, even more than typical biotech which is already the riskest sector.
I post to remind people that much of the speculation and positive spin they read has been written before. I like to remind folks that we are nearing another reverse split cycle similar to a few years ago and that those investors were decimated just like they will be. I post to remind folks that not all that glitters is gold and that there are many greedy people nearby that are professional manipulators.
No I don't feel bad about providing caution to anyone considering this as an investment. What about all the cheerleaders around here? Should they feel bad about the part they may have played in folks losing nearly everything in this investment? Maybe folks taking a major hit to their entire portfolio based on their belief in NWBO management's promises over the years.
Just passing the time as we go on 7 months and counting without any news on any front while the stock dies a slow and painful death. Why do you post? Talked to Les lately?
I think the longs should be jumping up and down for joy at these prices. Load em up! And options too!!
Beware the Ides of March. LMAO!!
A nearly 100% return is now necessary to get back to $3. 200% to reach $4.50. 300% to reach $6. 400% to reach $7.5. Only need a 6 bagger plus for those of you who bought over $10 to break even.
Hopefully you all see how unlikely it is that you will ever get your money back. The continued drop in price, increased dilution and forthcoming reverse split will make it even more impossible. It's gone for good Jack!!
Just a few days ago folks were gloating about their purchases in the low to mid 2's...
Many warnings by many people unheeded. Go NWBO!!
Good to see the options traders and day traders are still hard at it. Feel sorry for all of the folks who bought the Jan 2017 options thinking they were safe from deterioration. Someone is going to enjoy a huge payday when they all expire worthless.
Hey look at that. It seems ALL of these patients are living longer.
No further comment on this? Very strange they found it necessary to increase the S3 already. Unless this last dilution includes a huge issuance of warrants to Cognate under the MFN clause.
I appreciate your posts doc. Curious how one would prepare for the possibility of a scorched earth scenario where NWBO is taken private for pennies on the dollar?
AVII77, for the record, are you short or have you conducted your research on NWBO for anyone else to use in their investment decisions concerning NWBO? Thanks
"It was not for the control arm OS. It was for the SOC., and even though they use the same Stupp's protocol, she was blinded from the control arm. So it is important to make that distinction."
But there really isn't an SOC group in this trial for OS is there? I thought it was basically early DCVAX vs. Dcvax after progression. What am I missing?
Good call on Rintega, Beach. Hope you are as right about NWBO.
General question for you or anyone else. Does Rintega's failure at this juncture provide a larger potential bounce for NWBO on positive news? Market share uncertainty has been slightly diminished today which would seem to be potentially favorable. Thoughts?
The chance of a lifetime to buy this at $1.65, right? There are only a few people that know about this incredible opportunity so you better act quick. Add more now before the institutions find this diamond in the rough.
Not only do you have the incredibly high bar for achieving success in the GBM arena where everyone else's products are failing, you have many additional risks unique to NWBO. Better hurry and buy more!
Do you think it would be fair to say that all patients in this trial are living longer than historical norms? Hmm..interesting.
Imuc = immunotherapy treatment for GBM = clinical trial failure = investors wiped out.
CLDX = immunotherapy for GBM = clinical trial failure = investors decimated.
NWBO = immunotherapy for GBM = long partial clinical hold initiated (likely right after efficacy IA), principal investigator indicates all patients (including palacebo) are living longer and it "isn't helping" NWBO's trial. NWBO's chief scientific officer warns that pseduo professors "wreck havoc" on clinical trials = investors down 86% with more losses to come.
Do I need to connect the dots any further for you?
Cldx's failure doesn't bode well for NWBO. I expect the stock will continue down from here. Next dilution will be below $1.50. I expect shareholders (excluding Cognate and LP) will experience a 100% dilution from Dec 2015 through Dec 2016.
And yet not one word about those poor patients who now have one less option on the tabel. But I thought the patients were your primary focus, Dogood? Guess your intentions are becoming more and more clear all the time. Have a great day. Load you boat with NWBO. I really hope you are very overweight in NWBO in the $10's.
Science Friday on NPR discussing immuno therapy. Maybe someone should call in and mention DCVAX. Maybe one of you doctors..
DoGood, if the technology turns out to be successful, but the only folks that profit financially are the company execs and LP, will you be happy, indifferent, or upset? Thanks
If the market is up or flat, NWBO will trade at $1.70. When the market drops, we will drop. Sorry, that's just how it works. There's no upside here.
How low does everyone think we will go in the coming weeks with no news? I predict the $1.30 to $1.50 range in the short term depending on what the overall market does. Next capital raise around $1.10 - $1.25. Probably a 20% or so dilution for another $10M for the Direct Phase 2 that won't start. GL
Maybe LP dilutes the hell out of NW through the MFN. He realizes the gig is up and dumps 25m shares to book his losses and pursue legal damages. The price drops into penny range. Linda quickly completes the take private transfer at those prices. That's one scenario. Probably all legal too.
Why do you think they also increased the S3 to more than 150m? Maybe there was a huge issuance of shares to Cognate under the MFN. Don't know what to make of that.
No I didn't forget this (once again courtesy of beartrap12) as of December 18th:
"She said the trial is close to completing enrollment... that enrollment would be done about January, or February."
I'm sure this was best case scenario, you know, if the screening hold were lifted in short order like they hoped. But it hasn't been and there's no reason to believe enrollment is complete.
Haha, don't trip over yourself backpedaling. You went from "clear that the trial was fully enrolled around Halloween" to "sufficiently enrolled" (whatever that means). I prefer to believe Linda.
Can you provide just one example of a company that applied for AA at the end of their trial?
Interesting how clear it is to you that full enrollment was reached around Halloween when Linda Powers said it had not been reached as of the annual meeting in December. Or did you forget about that too?
I think it's within a couple of days for a majority owner. Unless you are Cognate or Toucan. Then it's whenever the heck you want or after the SEC sends a warning..
Hi Flipper. I know it must have been painful for you to realize that AA hadn't been applied for in December when LP made those comments. Seeing as how you had been stumping on that as the reason for the hold and the "regulatory submittal" since August. Remember all of your posts for all of those months? And then to have LP herself say nope that's not what's going on. Must have stung a little.
It reminds me of a time when one of our favorite posters put out a considerable effort to develop a statistical analysis of the L trial. When asked about it NWBO management just laughed and shook their heads in disbelief. I'm sure it would have been a similar reaction if they would have read all of your posts on AA last fall. But then again, maybe the point of it all was to make others hang on to that idea, that fantasy, and most importantly their shares..
Pretty sure he would have to report it and he hasn't. I think we can rule that out.
When asked about the delay in starting the phase II trials, Les said that there was no delay at all..
This was my favorite part of the whole dialogue. Haha. Delay? What delay? Everything is proceeding right on schedule. So, was this the intended timeline all along?? That sure isn't what they led investors to believe since 2014. This is the kind of deception that makes my blood boil. Maybe there's an assumption that the type of folks invested here would just go right along with whatever is said without stopping to think about it..
Maybe I'm overreacting. Maybe this conversation never actually happened and this is nothing more than a veiled attempt by the shorts to make Les look really bad.
As I recall, when they explained the "Active, not recruiting" and the "This study is ongoing, but not recruiting participants" change to the clinical trial.gov site, there was some mention of extending the period out by one month to October 2016 due to the delay.
However, it still reads September 2016.
Yes, and it previously said September of 2015, until they changed it last fall. They knew long before they changed it that it wouldn't end September 2015. It will say September 2016, until they change it again.
There is a screening hold right now. Referring to it in that manner serves as a description for what is happening overall. And when they are able to tell us, it will be "lifted" so-to-speak.
IT is a screening hold. NWBO needs IT to be lifted to continue screening in order to complete enrollment. The trial has been delayed because of IT. Linda would never have made the comments about the delay in December if the trial was completely enrolled, which we know it wasn't because Linda said it wasn't
I don't expect you to accept this explanation, and I understand if others don't either. It works for me, I share it with all of you, and you can poke holes in it all day long. I simply do not care.
No spin on the AA explanation. You don't wait for the end of a trial to apply. That is the point of accelerating it. I have no certainty that they are applying for AA. I know they intended per the April 2013 protocol. Maybe they changed their mind.
That's right. You don't apply for AA at the end of a trial. And Linda never said she would apply for AA. Rather she has said on multiple occasions that she intends to see the trial through to the end. I interpret her comments about AA to mean exactly what she said. No AA. She will wait until the end to apply for approval and it won't be AA. I know how important the AA theory is to the idea that something great is right around the corner. I call it the zombie theory, because it just won't die. Even when the CEO chops the head off, it still comes back to life.
Whatever it is... it's good. And for one, I will not let others here spin good news into bad. I accept my decision to hold and buy when I can is mine and my husband's alone. You may do whatever you please and it will make no difference to me. What I do should make no difference to you. Put my posts on ignore and you won't have to read the rays of sunshine I bestow here.
The "good news" had nothing to do with the halt and everything to do with the 300 enrolled. You know that and are choosing to take advantage of the way NWBO spun this little tidbit out there for all the suckers to gobble right up. You have been steady as she goes. Steady as it goes right down the old turd swirly. I have a feeling you would still bestow rays of sunshine if the allegations are proven to be true and charges are filed, if the trial goes up in flames, or if the company goes belly up due to lack of financing. It's just what you do. For whatever reason, it's just what you do. All JMHO of course :)
Exactly. If the last two raises were to existing long investors, the short shares are still out there. If someone like Toucan just pushed in $22m more chips in the last two months, it would be quite interesting wouldn't it? That's why I thought it was a question worth asking.
Well that's one way to spin it. I am more inclined to believe Linda Powers when she said that the screening halt has delayed the trial. How would it delay the trial if there were enough patients in the pipeline to complete enrollment? It wouldn't and you know that. They weren't fully enrolled in December and they aren't now. Why would Les even mention the screening hold lifting if they had already reached full enrollment. They wouldn't need to screen any more.
You should open a cheese shop. We'll call it Senti's Swiss. Everything you are selling today is chock full of holes..
Nice of Linda to help out those shorts. Now why would she do that? Give me one good reason why she would do that? Maybe she wanted to help them cash out? Are you implying that maybe Linda is in cahots with the shorts and gave them a generous escape route? She couldn't find money anywhere else? The investment isn't attractive enough at $1.70 for Toucan to step in with a purchase or a bridge loan for a few weeks until the butterfly emerges? Yeah right..
Come on, Flipper. Really?? We've had multiple conversations about this and now you're going to play dumb like it's totally foreign to you. Why? Once again, here's what was reported by multiple people who attended the annual meeting.
"The fact that they were so busy cleaning up site information made some of us suspect they are applying for Fast Track or Accelerated Approval. Linda said no to AA” Beartrap12
Another post from Beartrap12:
"She (Linda Powers) talked about accelerated approval and said that they can't apply for it until the trial reaches its end."
Wow! And how do you know this with such certainty good sir?
Why are you all acting as if this is a new discovery? Linda told us last August they were submitting a package and in a dialogue with a regulator. All of a sudden folks are like, wow news flash this is in the hands of a regulator, not the DMC!!
I don't get it. The spin here makes my head hurt. There's nothing new to talk about. The share price is in the crapper. Linda knows there's nothing significant on the horizon and just financed at $1.70. Pure desperation as I see it. All these conversations with Les and no one asks who the financier was for the last two raises? Now that might be something of interest.
Don't play coy. You know what I'm talking about. Enough with the AA fantasy. It's not on the table!
Not directed at you in any way. Sorry, I should have put that under a new post instead of a reply so that you wouldn't think it was. You're one of very few here with any credibility.
I feel you smokey. The tax issue was the exact reason I stayed in too. Lost 65% of my investment to save 15% on taxes. Live and learn I guess. It's been a painful lesson.
Do you remember when someone asked Linda at the annual shareholders meeting about AA? I do. Her answer was no. Now, you were saying?
Nice to see the XBI up 4%. Maybe it has finally bottomed out. Anyone notice cldx was up another 11% today? It's nice to have some green in a few places. Good places to invest exist all around.
I would describe the trading activity of yesterday and today with NWBO as an orderly dump of hundreds of thousands of shares. Exactly as expected following the toxic financing. It will continue for a few more days as the seller works the stock to maximize sale proceeds. Then look for the down trend to continue. I'm expecting another 25% to 50% drop from here with no news. Then the reverse split. And we'll start it all over again. Just like a few years ago. A few of us remember that all to well. And history repeats. But good news is right around the corner. Stay tuned!
How can you make comments like this when there is clearly no shortage of shares available in the $1.60's. It makes no sense! Do you think anyone actually believes you? The shorts have no need to pressure people into selling. They just covered. Buyers have no reason to pressure people into selling, there's no shortage. It really is the weakest argument one can make right now. At least try to come up with something believable.