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$TOMDF News:
Todos Medical Initiates Validation Plan for PCR-based MonkeyPox Test at CLIA/CAP Clinical Testing Laboratory Provista Diagnostics
New York, NY, and Tel Aviv, ISRAEL, Aug. 03, 2022 (GLOBE NEWSWIRE) -- via NewMediaWire -- Todos Medical, Ltd. (OTCQB: TOMDF), a comprehensive medical diagnostics and related solutions company, today announced that its CLIA/CAP-certified laboratory Provista Diagnostics has initiated a validation plan for PCR-based MonkeyPox testing. Under the plan, the Company is validating multiple PCR assays for MonkeyPox and will launch the most sensitive for lesion-based and saliva-based sample collections. While lesion-based testing is the current standard of care according to CDC guidelines, saliva-based sample collection is currently undergoing intense research that could open up the potential for testing of asymptomatic or very early-stage patients at high risk of severe disease (such as immunocompromised patients) that could result in earlier diagnosis and early intervention with therapeutic drugs such as Tecovirimat (TPOXX). TPOXX is an investigational drug candidate, and currently only available under an expanded access Investigational New Drug (EA-IND) protocol. The MonkeyPox tests are being developed as Laboratory Developed Tests (LDTs). A recent peer-reviewed article describing strong correlation of the sensitivity of lesion and saliva-based PCR testing was recently published in the journal Eurosurveillance: https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2022.27.28.2200503
“The significant investment we made to automate PCR testing at Provista to maximize COVID testing capacity can now be partially redeployed towards MonkeyPox as we prepare to help the nation scale-up MonkeyPox testing capacity to meet the emerging public health crisis,” said Gerald E. Commissiong, President & CEO of Todos Medical.
About Todos Medical Ltd.
Founded in Rehovot, Israel with offices in New York City, Todos Medical Ltd. (OTCQB: TOMDF) engineers life-saving diagnostic solutions for the early detection of a variety of cancers. The Company's state-of-the-art and patented Todos Biochemical Infrared Analyses (TBIA) is a proprietary cancer-screening technology using peripheral blood analysis that examines cancer's influence on the immune system, looking for biochemical changes in blood mononuclear cells and plasma. Todos’ two internally developed cancer-screening tests, TMB-1 and TMB-2 have received a CE mark in Europe. Todos recently acquired U.S.-based medical diagnostics company Provista Diagnostics, Inc. to gain rights to its Alpharetta, Georgia-based CLIA/CAP certified lab currently performing PCR COVID testing, Long COVID Panel, and Provista's proprietary commercial-stage Videssa® breast cancer blood test.
Todos is also developing blood tests for the early detection of neurodegenerative disorders, such as Alzheimer's disease. The Lymphocyte Proliferation Test (LymPro Test™) is a diagnostic blood test that determines the ability of peripheral blood lymphocytes (PBLs) and monocytes to withstand an exogenous mitogenic stimulation that induces them to enter the cell cycle. It is believed that certain diseases, most notably Alzheimer's disease, are the result of compromised cellular machinery that leads to aberrant cell cycle re-entry by neurons, which then leads to apoptosis. LymPro is unique in the use of peripheral blood lymphocytes as a surrogate for neuronal cell function, suggesting a common relationship between PBLs and neurons in the brain.
Todos formed the Israeli-based majority-owned joint venture 3CL Pharma, Ltd with NLC Pharma in March of 2022 to consolidate all of the intellectual property pursuing the development of diagnostic tests targeting the 3CL protease, as well as 3CL protease inhibitor botanical and pharmaceutical products that target a fundamental reproductive mechanism of coronaviruses. 3CL Pharma, through Todos’ brand, has commercialized the 3CL protease inhibitor immune support dietary supplement Tollovid® in the United States, is developing the dual mechanism 3CL protease inhibitor & anti-cytokine therapeutic drug candidate Tollovir®, while also developing the 3CL protease inhibitor diagnostic TolloTest™.
To purchase Tollovid please visit Amazon or www.MyTollovid.com. For more information, please visit https://www.todosmedical.com/.
Forward-looking Statements
Certain statements contained in this press release may constitute forward-looking statements. For example, forward-looking statements are used when discussing our expected clinical development programs and clinical trials. These forward-looking statements are based only on current expectations of management, and are subject to significant risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements, including the risks and uncertainties related to the progress, timing, cost, and results of clinical trials and product development programs; difficulties or delays in obtaining regulatory approval or patent protection for product candidates; competition from other biotechnology companies; and our ability to obtain additional funding required to conduct our research, development and commercialization activities. In addition, the following factors, among others, could cause actual results to differ materially from those described in the forward-looking statements: changes in technology and market requirements; delays or obstacles in launching our clinical trials; changes in legislation; inability to timely develop and introduce new technologies, products and applications; lack of validation of our technology as we progress further and lack of acceptance of our methods by the scientific community; inability to retain or attract key employees whose knowledge is essential to the development of our products; unforeseen scientific difficulties that may develop with our process; greater cost of final product than anticipated; loss of market share and pressure on pricing resulting from the competition; and laboratory results that do not translate to equally good results in real settings, all of which could cause the actual results or performance to differ materially from those contemplated in such forward-looking statements. Except as otherwise required by law, Todos Medical does not undertake any obligation to publicly release any revisions to these forward-looking statements to reflect events or circumstances after the date hereof or to reflect the occurrence of unanticipated events. For a more detailed description of the risks and uncertainties affecting Todos Medical, please refer to its reports filed from time to time with the U.S. Securities and Exchange Commission.
Todos Corporate Contact:
Daniel Hirsch
CFO
Todos Medical
917-983-4229 x 104
Dan.h@todosmedical.com
$TOMDF News:
Todos Medical Initiates Validation Plan for PCR-based MonkeyPox Test at CLIA/CAP Clinical Testing Laboratory Provista Diagnostics
New York, NY, and Tel Aviv, ISRAEL, Aug. 03, 2022 (GLOBE NEWSWIRE) -- via NewMediaWire -- Todos Medical, Ltd. (OTCQB: TOMDF), a comprehensive medical diagnostics and related solutions company, today announced that its CLIA/CAP-certified laboratory Provista Diagnostics has initiated a validation plan for PCR-based MonkeyPox testing. Under the plan, the Company is validating multiple PCR assays for MonkeyPox and will launch the most sensitive for lesion-based and saliva-based sample collections. While lesion-based testing is the current standard of care according to CDC guidelines, saliva-based sample collection is currently undergoing intense research that could open up the potential for testing of asymptomatic or very early-stage patients at high risk of severe disease (such as immunocompromised patients) that could result in earlier diagnosis and early intervention with therapeutic drugs such as Tecovirimat (TPOXX). TPOXX is an investigational drug candidate, and currently only available under an expanded access Investigational New Drug (EA-IND) protocol. The MonkeyPox tests are being developed as Laboratory Developed Tests (LDTs). A recent peer-reviewed article describing strong correlation of the sensitivity of lesion and saliva-based PCR testing was recently published in the journal Eurosurveillance: https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2022.27.28.2200503
“The significant investment we made to automate PCR testing at Provista to maximize COVID testing capacity can now be partially redeployed towards MonkeyPox as we prepare to help the nation scale-up MonkeyPox testing capacity to meet the emerging public health crisis,” said Gerald E. Commissiong, President & CEO of Todos Medical.
About Todos Medical Ltd.
Founded in Rehovot, Israel with offices in New York City, Todos Medical Ltd. (OTCQB: TOMDF) engineers life-saving diagnostic solutions for the early detection of a variety of cancers. The Company's state-of-the-art and patented Todos Biochemical Infrared Analyses (TBIA) is a proprietary cancer-screening technology using peripheral blood analysis that examines cancer's influence on the immune system, looking for biochemical changes in blood mononuclear cells and plasma. Todos’ two internally developed cancer-screening tests, TMB-1 and TMB-2 have received a CE mark in Europe. Todos recently acquired U.S.-based medical diagnostics company Provista Diagnostics, Inc. to gain rights to its Alpharetta, Georgia-based CLIA/CAP certified lab currently performing PCR COVID testing, Long COVID Panel, and Provista's proprietary commercial-stage Videssa® breast cancer blood test.
Todos is also developing blood tests for the early detection of neurodegenerative disorders, such as Alzheimer's disease. The Lymphocyte Proliferation Test (LymPro Test™) is a diagnostic blood test that determines the ability of peripheral blood lymphocytes (PBLs) and monocytes to withstand an exogenous mitogenic stimulation that induces them to enter the cell cycle. It is believed that certain diseases, most notably Alzheimer's disease, are the result of compromised cellular machinery that leads to aberrant cell cycle re-entry by neurons, which then leads to apoptosis. LymPro is unique in the use of peripheral blood lymphocytes as a surrogate for neuronal cell function, suggesting a common relationship between PBLs and neurons in the brain.
Todos formed the Israeli-based majority-owned joint venture 3CL Pharma, Ltd with NLC Pharma in March of 2022 to consolidate all of the intellectual property pursuing the development of diagnostic tests targeting the 3CL protease, as well as 3CL protease inhibitor botanical and pharmaceutical products that target a fundamental reproductive mechanism of coronaviruses. 3CL Pharma, through Todos’ brand, has commercialized the 3CL protease inhibitor immune support dietary supplement Tollovid® in the United States, is developing the dual mechanism 3CL protease inhibitor & anti-cytokine therapeutic drug candidate Tollovir®, while also developing the 3CL protease inhibitor diagnostic TolloTest™.
To purchase Tollovid please visit Amazon or www.MyTollovid.com. For more information, please visit https://www.todosmedical.com/.
Forward-looking Statements
Certain statements contained in this press release may constitute forward-looking statements. For example, forward-looking statements are used when discussing our expected clinical development programs and clinical trials. These forward-looking statements are based only on current expectations of management, and are subject to significant risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements, including the risks and uncertainties related to the progress, timing, cost, and results of clinical trials and product development programs; difficulties or delays in obtaining regulatory approval or patent protection for product candidates; competition from other biotechnology companies; and our ability to obtain additional funding required to conduct our research, development and commercialization activities. In addition, the following factors, among others, could cause actual results to differ materially from those described in the forward-looking statements: changes in technology and market requirements; delays or obstacles in launching our clinical trials; changes in legislation; inability to timely develop and introduce new technologies, products and applications; lack of validation of our technology as we progress further and lack of acceptance of our methods by the scientific community; inability to retain or attract key employees whose knowledge is essential to the development of our products; unforeseen scientific difficulties that may develop with our process; greater cost of final product than anticipated; loss of market share and pressure on pricing resulting from the competition; and laboratory results that do not translate to equally good results in real settings, all of which could cause the actual results or performance to differ materially from those contemplated in such forward-looking statements. Except as otherwise required by law, Todos Medical does not undertake any obligation to publicly release any revisions to these forward-looking statements to reflect events or circumstances after the date hereof or to reflect the occurrence of unanticipated events. For a more detailed description of the risks and uncertainties affecting Todos Medical, please refer to its reports filed from time to time with the U.S. Securities and Exchange Commission.
Todos Corporate Contact:
Daniel Hirsch
CFO
Todos Medical
917-983-4229 x 104
Dan.h@todosmedical.com
$RBRXF more News!
https://www.otcmarkets.com/stock/RBRXF/news/story?e&id=2203718
Rhino Biotech to Present at the Planet Microcap Showcase
ANGUILLA, BWI / ACCESSWIRE / May 4, 2022 / Rhino Biotech Limited (OTCPINK:RBRXF), a Biotech Company ("Rhino Biotech" or "the Company"), today announced it will be presenting at the SNN Network Planet MicroCap Showcase on May 4, 2022 at 2:30 p.m. Pacific Time. Chief Strategy Officer , Justin DeAngelis will host the presentation and answer questions from investors.
To access the live presentation, please use the following information:
Planet MicroCap Showcase 2022 in Las Vegas
Date: Wednesday, May 4,2022
Time: 2.30 p.m. PDT
Webcast: https://www.issuerdirect.com/order/snn/rhino/
About Rhino Biotech Limited.
Rhino Biotech, specializes in producing active ingredients and compounds derived from plants, fungi and other micro organisms for use in nutraceuticals and preventative and curative bio-pharmaceuticals, all with the intention of fortifying health in mammals.
For more information, visit
Website: rhinobiotech.com
Investor Relations: ir.rhinobiotech.com
Recent Milestones
Agritech division licensed in several states
Operate a 27,000 Square Foot fully automated lab grade facility completed with deep water culture chambers and cloning rooms
2 Proprietary CBG strains bread and engineered over 14 Iterations
Developed and Manufactured 440 Nutraceutical products along with various certifications, with some products being NSF certified (Certified for Sport)
Developed 25 Health specific nutraceutical formulations
1 proprietary strain being used for Medical Research in partnership with Penn State and PA Options for Wellness.
Developed a range of Pet and Equine Nutraceuticals and Topical products
Developed a range of Energy Drinks, Vitamin Water Drinks and other Nutraceutical Waters
Secured the option on a large cannabinoid focused technology patent portfolio
First revenue generated from Seed and Biomass sales
If you would like to attend the 2022 Planet MicroCap Showcase and register for a 1-on-1 meeting with Rhino Biotech, please make sure you are registered here:
https://planetmicrocapshowcase.com/signup
1-on-1 meetings will be scheduled and conducted in person at the conference venue.
About SNN Network
SNN Network is your multimedia financial news platform for discovery, transparency and due diligence. This is your one-stop hub to find new investment ideas, check in on watchlist, gather the most up-to-date information on the Small-, Micro-, Nano-Cap market with the goal to help you towards achieving your wealth generation goals. Follow the companies YOU want to know more about; read and watch content from YOUR favorite finance and investing influencers; create YOUR own watchlist and screen for ideas YOU'RE interested in; find out about investor conferences YOU want to attend - all here on SNN Network.
Cautionary Statement Regarding Forward-Looking Statements
This release may contain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements may be identified by the use of words such as "anticipate," "believe," "plan," "estimate" "expect," "intend," "may," "will," "would," "could," "should," "might," "potential," or "continue," and variations or similar expressions. Readers should not unduly rely on these forward- looking statements, which are not a guarantee of future performance. There can be no assurance that forward-looking statement will prove to be accurate. As all such forward- looking statements involve known and unknown risks, uncertainties and other factors which may cause actual results or future event to differ materially from the forward- looking statements. Such risks include, but may not be limited to: general economic and business conditions; our ability to obtain financing; technology changes; competition; changes in strategy or development plans; governmental regulations and the ability or failure to comply with governmental regulations; the timing of anticipated results; and other factors referenced in Rhino Biotech's filings with securities regulators. For a discussion of further risks and uncertainties related to our business, please refer to our public company reports filed with the US Securities and Exchange Commission. All forward-looking statements are made as of the date hereof and are subject to change. Except as required by law, we assume no obligation to update such statements. This communication does not constitute an offer or solicitation of an offer for sale of any securities in any jurisdiction.Except as required by law, the Company disclaims any obligation to update or publicly announce any revisions to any of the forward-looking statements contained in this news release.
Contacts
https://www.accesswire.com/users/newswire/images/700151/najc8yfnptwdsrcvwbrpi8ereyzxst4a.png
Rhino Biotech Limited
Justin DeAngelis, Chief Strategy Officer
Phone : 970-779-3199
Bernie O'Neill, Chief Operating Officer
Phone: 203-695-8571
Email: hello@rhinobiotech.com
https://www.accesswire.com/users/newswire/images/700151/gatdnsgbu5wvf6lkchprdwcfcuxqw9n5.jpeg
Investor Relations
Porter, LeVay & Rose
Michael Porter, President
Phone: 212.564.4700
Email: info@plrinvest.com
https://www.accesswire.com/users/newswire/images/700151/nqrghhxf8fngvdg8prhjc2hby2d3wbhr.png
Investment Advisors
John McAuliffe
Managing Director
Paulson Investment Company, LLC
4905 W Laurel Street, Suite 101
Tampa, FL 33607
Direct Dial: (813) 369-5889
www.paulsoninvestment.com
SOURCE: Rhino Biotech
View source version on accesswire.com:
https://www.accesswire.com/700151/Rhino-Biotech-to-Present-at-the-Planet-Microcap-Showcase
$RBRXF more News!
https://www.otcmarkets.com/stock/RBRXF/news/story?e&id=2203718
Rhino Biotech to Present at the Planet Microcap Showcase
ANGUILLA, BWI / ACCESSWIRE / May 4, 2022 / Rhino Biotech Limited (OTCPINK:RBRXF), a Biotech Company ("Rhino Biotech" or "the Company"), today announced it will be presenting at the SNN Network Planet MicroCap Showcase on May 4, 2022 at 2:30 p.m. Pacific Time. Chief Strategy Officer , Justin DeAngelis will host the presentation and answer questions from investors.
To access the live presentation, please use the following information:
Planet MicroCap Showcase 2022 in Las Vegas
Date: Wednesday, May 4,2022
Time: 2.30 p.m. PDT
Webcast: https://www.issuerdirect.com/order/snn/rhino/
About Rhino Biotech Limited.
Rhino Biotech, specializes in producing active ingredients and compounds derived from plants, fungi and other micro organisms for use in nutraceuticals and preventative and curative bio-pharmaceuticals, all with the intention of fortifying health in mammals.
For more information, visit
Website: rhinobiotech.com
Investor Relations: ir.rhinobiotech.com
Recent Milestones
Agritech division licensed in several states
Operate a 27,000 Square Foot fully automated lab grade facility completed with deep water culture chambers and cloning rooms
2 Proprietary CBG strains bread and engineered over 14 Iterations
Developed and Manufactured 440 Nutraceutical products along with various certifications, with some products being NSF certified (Certified for Sport)
Developed 25 Health specific nutraceutical formulations
1 proprietary strain being used for Medical Research in partnership with Penn State and PA Options for Wellness.
Developed a range of Pet and Equine Nutraceuticals and Topical products
Developed a range of Energy Drinks, Vitamin Water Drinks and other Nutraceutical Waters
Secured the option on a large cannabinoid focused technology patent portfolio
First revenue generated from Seed and Biomass sales
If you would like to attend the 2022 Planet MicroCap Showcase and register for a 1-on-1 meeting with Rhino Biotech, please make sure you are registered here:
https://planetmicrocapshowcase.com/signup
1-on-1 meetings will be scheduled and conducted in person at the conference venue.
About SNN Network
SNN Network is your multimedia financial news platform for discovery, transparency and due diligence. This is your one-stop hub to find new investment ideas, check in on watchlist, gather the most up-to-date information on the Small-, Micro-, Nano-Cap market with the goal to help you towards achieving your wealth generation goals. Follow the companies YOU want to know more about; read and watch content from YOUR favorite finance and investing influencers; create YOUR own watchlist and screen for ideas YOU'RE interested in; find out about investor conferences YOU want to attend - all here on SNN Network.
Cautionary Statement Regarding Forward-Looking Statements
This release may contain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements may be identified by the use of words such as "anticipate," "believe," "plan," "estimate" "expect," "intend," "may," "will," "would," "could," "should," "might," "potential," or "continue," and variations or similar expressions. Readers should not unduly rely on these forward- looking statements, which are not a guarantee of future performance. There can be no assurance that forward-looking statement will prove to be accurate. As all such forward- looking statements involve known and unknown risks, uncertainties and other factors which may cause actual results or future event to differ materially from the forward- looking statements. Such risks include, but may not be limited to: general economic and business conditions; our ability to obtain financing; technology changes; competition; changes in strategy or development plans; governmental regulations and the ability or failure to comply with governmental regulations; the timing of anticipated results; and other factors referenced in Rhino Biotech's filings with securities regulators. For a discussion of further risks and uncertainties related to our business, please refer to our public company reports filed with the US Securities and Exchange Commission. All forward-looking statements are made as of the date hereof and are subject to change. Except as required by law, we assume no obligation to update such statements. This communication does not constitute an offer or solicitation of an offer for sale of any securities in any jurisdiction.Except as required by law, the Company disclaims any obligation to update or publicly announce any revisions to any of the forward-looking statements contained in this news release.
Contacts
https://www.accesswire.com/users/newswire/images/700151/najc8yfnptwdsrcvwbrpi8ereyzxst4a.png
Rhino Biotech Limited
Justin DeAngelis, Chief Strategy Officer
Phone : 970-779-3199
Bernie O'Neill, Chief Operating Officer
Phone: 203-695-8571
Email: hello@rhinobiotech.com
https://www.accesswire.com/users/newswire/images/700151/gatdnsgbu5wvf6lkchprdwcfcuxqw9n5.jpeg
Investor Relations
Porter, LeVay & Rose
Michael Porter, President
Phone: 212.564.4700
Email: info@plrinvest.com
https://www.accesswire.com/users/newswire/images/700151/nqrghhxf8fngvdg8prhjc2hby2d3wbhr.png
Investment Advisors
John McAuliffe
Managing Director
Paulson Investment Company, LLC
4905 W Laurel Street, Suite 101
Tampa, FL 33607
Direct Dial: (813) 369-5889
www.paulsoninvestment.com
SOURCE: Rhino Biotech
View source version on accesswire.com:
https://www.accesswire.com/700151/Rhino-Biotech-to-Present-at-the-Planet-Microcap-Showcase
$RBRXF News!
Rhino Biotech has acquired cannabis genetics company and a biopharmaceutical company.
Press Release | 05/04/2022
ANGUILLA, BRITISH OVERSEAS TERRITORIES / ACCESSWIRE / May 4, 2022 / Rhino Biotech Limited (OTC:RBRXF)
294 Heywood House,
South Hill
1A AI-2640, Anguilla
Rhino Biotech has acquired cannabis genetics company and a biopharmaceutical company.
Rhino Biotech Limited (OTC:RBRXF) has entered the Biotech market with a specific focus on scientifically backed and clinically proven plant and fungi derived compounds for use in nutraceuticals and preventative and curative Biopharmaceuticals.
The company aims to achieve its initial growth in this arena by way of strategic acquisitions that compliment our core focus and in turn will benefit from our vertically integrated strategies and partnerships.
BRIEF OVERVIEW OF THE TRANSACTION
Rhino Biotech entered into several agreements and has acquired:-
all the membership interest in Colorado-based Artesian Valley Farms, LLC, (dba Artesian Valley Agritech) for an aggregate of $14,500,000 in shares/stock and $3,400,000 in financing along with all of the membership interest in Nevada based, JRD Ventures, LLC for an aggregate of $3,100,000 in shares/stock.
and all of the common shares/stock of Rhino Biotech, Inc., an Ohio corporation, for an aggregate of $10,000,000 in shares of Rhino Biotech Limited
This transaction allows the company to compete in the lucrative biotech market with specific focus on natural plant based health and wellness and in moving forward, continue to invest in the fortification of health
Artesian Valley Agritech, owns and operates a state of the art, highly automated 27,000 Sq/ft medical grade indoor cultivation, genetics and cloning facility, operating on 13 Acres located in Durango, Colorado, Licensed under the Colorado Department of Agriculture for 19,000 Sq/Ft of indoor production and 10 acres outdoor production.
Artesian Valley Agritech, through its expertise in biogenetics and genomics, has produced several proprietary strains of the Cannabis Sativa L. genus engineered specifically to produce high levels of cannabinoids such as CBG, CBN and CBC and contain almost no psychoactive compounds.
Among these proprietary strains is "Chiron" the divisions's first CBG seed release aimed at medical research and has under laboratory analysis tested as high as 18.1 % in CBG and 0.1- 0.2% THC, with a 98% Germination Rate, and at 96-100% female sex. In addition to these statistics, the divisions research team specifically bread this strain for resistance to molds and mildews, as well as frost; enabling propagation suitability with extremely high yields in nearly all climates.
"Nautilus" is the farm's second release and the first global CBG seed release that is licensed to selected growers to produce biomass to extract targeted isolates and compounds.
JRD Ventures partnered with Artesian Valley Farms and was instrumental in the development of Artesian Valley Agritech, including in the growth and genetic diversification of its inventory. In furtherance of the business JRD Ventures independently developed proprietary standard operating procedures, recipes, trade secrets, and other intellectual property, and subsequently granted Artesian Valley Agritech the right to use such information in exchange for a 10% share in the net revenues generated by Artesian Valley Agritech derived from such intellectual property. Acquiring JRD Ventures as part of the Artesian Valley Agritech transaction was paramount to the continued success of Artesian Valley Agritech and the business development of Rhino Biotech.
Rhino Biotech, Inc. is a manufacturer, marketer and distributor natural health and wellness nutraceutical and nutritional products. The company has further developed proprietary formulations that fortify health through the application of nutraceuticals and biopharmaceuticals. Rhino's range of compounds used in its products are derived from plants, fungi and micro-organisms. These compounds may include cannabinoid isolates, chemical compounds extracted from the Cannabis Sativa L. plant grown specifically for medicinal use as well as chemical compounds extracted from fungi and fruiting bodies grown in medical grade environments for medicinal use
Safe Harbor Statement
This communication may contain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements may be identified by the use of words such as "anticipate," "believe," "plan," "estimate" "expect," "intend," "may," "will," "would," "could," "should," "might," "potential," or "continue," and variations or similar expressions. Readers should not unduly rely on these forward- looking statements, which are not a guarantee of future performance. There can be no assurance that forward-looking statement will prove to be accurate. As all such forward- looking statements involve known and unknown risks, uncertainties and other factors which may cause actual results or future event to differ materially from the forward- looking statements. Such risks include, but may not be limited to: general economic and business conditions; our ability to obtain financing; technology changes; competition; changes in strategy or development plans; governmental regulations and the ability or failure to comply with governmental regulations; the timing of anticipated results; and other factors referenced in Rhino Biotech's filings with securities regulators. For a discussion of further risks and uncertainties related to our business, please refer to our public company reports filed with the US Securities and Exchange Commission. All forward-looking statements are made as of the date hereof and are subject to change. Except as required by law, we assume no obligation to update such statements. This communication does not constitute an offer or solicitation of an offer for sale of any securities in any jurisdiction.
Contact:
P: +1 312-265-4165
mail: info@rhinobiotech.com
1714 Duchess Drive,Longmont, CO 80501
Corporate: rhinobiotech.com
Investor Relations: ir.rhinobiotech.com
Rhino Biotech Limited has further retained Paulson Investment Company, LLC as its financial advisor for the transaction and any future capital raise the Company may seek.
John McAuliffe
Managing Director
Paulson Investment Company, LLC
4905 W Laurel Street, Suite 101
Tampa, FL 33607
Direct Dial: (813) 369-5889
www.paulsoninvestment.com
https://www.otcmarkets.com/stock/RBRXF/news/Rhino-Biotech-has-acquired-cannabis-genetics-company-and-a-biopharmaceutical-company?id=355533
$RBRXF News!
Rhino Biotech has acquired cannabis genetics company and a biopharmaceutical company.
Press Release | 05/04/2022
ANGUILLA, BRITISH OVERSEAS TERRITORIES / ACCESSWIRE / May 4, 2022 / Rhino Biotech Limited (OTC:RBRXF)
294 Heywood House,
South Hill
1A AI-2640, Anguilla
Rhino Biotech has acquired cannabis genetics company and a biopharmaceutical company.
Rhino Biotech Limited (OTC:RBRXF) has entered the Biotech market with a specific focus on scientifically backed and clinically proven plant and fungi derived compounds for use in nutraceuticals and preventative and curative Biopharmaceuticals.
The company aims to achieve its initial growth in this arena by way of strategic acquisitions that compliment our core focus and in turn will benefit from our vertically integrated strategies and partnerships.
BRIEF OVERVIEW OF THE TRANSACTION
Rhino Biotech entered into several agreements and has acquired:-
all the membership interest in Colorado-based Artesian Valley Farms, LLC, (dba Artesian Valley Agritech) for an aggregate of $14,500,000 in shares/stock and $3,400,000 in financing along with all of the membership interest in Nevada based, JRD Ventures, LLC for an aggregate of $3,100,000 in shares/stock.
and all of the common shares/stock of Rhino Biotech, Inc., an Ohio corporation, for an aggregate of $10,000,000 in shares of Rhino Biotech Limited
This transaction allows the company to compete in the lucrative biotech market with specific focus on natural plant based health and wellness and in moving forward, continue to invest in the fortification of health
Artesian Valley Agritech, owns and operates a state of the art, highly automated 27,000 Sq/ft medical grade indoor cultivation, genetics and cloning facility, operating on 13 Acres located in Durango, Colorado, Licensed under the Colorado Department of Agriculture for 19,000 Sq/Ft of indoor production and 10 acres outdoor production.
Artesian Valley Agritech, through its expertise in biogenetics and genomics, has produced several proprietary strains of the Cannabis Sativa L. genus engineered specifically to produce high levels of cannabinoids such as CBG, CBN and CBC and contain almost no psychoactive compounds.
Among these proprietary strains is "Chiron" the divisions's first CBG seed release aimed at medical research and has under laboratory analysis tested as high as 18.1 % in CBG and 0.1- 0.2% THC, with a 98% Germination Rate, and at 96-100% female sex. In addition to these statistics, the divisions research team specifically bread this strain for resistance to molds and mildews, as well as frost; enabling propagation suitability with extremely high yields in nearly all climates.
"Nautilus" is the farm's second release and the first global CBG seed release that is licensed to selected growers to produce biomass to extract targeted isolates and compounds.
JRD Ventures partnered with Artesian Valley Farms and was instrumental in the development of Artesian Valley Agritech, including in the growth and genetic diversification of its inventory. In furtherance of the business JRD Ventures independently developed proprietary standard operating procedures, recipes, trade secrets, and other intellectual property, and subsequently granted Artesian Valley Agritech the right to use such information in exchange for a 10% share in the net revenues generated by Artesian Valley Agritech derived from such intellectual property. Acquiring JRD Ventures as part of the Artesian Valley Agritech transaction was paramount to the continued success of Artesian Valley Agritech and the business development of Rhino Biotech.
Rhino Biotech, Inc. is a manufacturer, marketer and distributor natural health and wellness nutraceutical and nutritional products. The company has further developed proprietary formulations that fortify health through the application of nutraceuticals and biopharmaceuticals. Rhino's range of compounds used in its products are derived from plants, fungi and micro-organisms. These compounds may include cannabinoid isolates, chemical compounds extracted from the Cannabis Sativa L. plant grown specifically for medicinal use as well as chemical compounds extracted from fungi and fruiting bodies grown in medical grade environments for medicinal use
Safe Harbor Statement
This communication may contain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements may be identified by the use of words such as "anticipate," "believe," "plan," "estimate" "expect," "intend," "may," "will," "would," "could," "should," "might," "potential," or "continue," and variations or similar expressions. Readers should not unduly rely on these forward- looking statements, which are not a guarantee of future performance. There can be no assurance that forward-looking statement will prove to be accurate. As all such forward- looking statements involve known and unknown risks, uncertainties and other factors which may cause actual results or future event to differ materially from the forward- looking statements. Such risks include, but may not be limited to: general economic and business conditions; our ability to obtain financing; technology changes; competition; changes in strategy or development plans; governmental regulations and the ability or failure to comply with governmental regulations; the timing of anticipated results; and other factors referenced in Rhino Biotech's filings with securities regulators. For a discussion of further risks and uncertainties related to our business, please refer to our public company reports filed with the US Securities and Exchange Commission. All forward-looking statements are made as of the date hereof and are subject to change. Except as required by law, we assume no obligation to update such statements. This communication does not constitute an offer or solicitation of an offer for sale of any securities in any jurisdiction.
Contact:
P: +1 312-265-4165
mail: info@rhinobiotech.com
1714 Duchess Drive,Longmont, CO 80501
Corporate: rhinobiotech.com
Investor Relations: ir.rhinobiotech.com
Rhino Biotech Limited has further retained Paulson Investment Company, LLC as its financial advisor for the transaction and any future capital raise the Company may seek.
John McAuliffe
Managing Director
Paulson Investment Company, LLC
4905 W Laurel Street, Suite 101
Tampa, FL 33607
Direct Dial: (813) 369-5889
www.paulsoninvestment.com
https://www.otcmarkets.com/stock/RBRXF/news/Rhino-Biotech-has-acquired-cannabis-genetics-company-and-a-biopharmaceutical-company?id=355533
$TOMDF News!
Todos Medical Reports 2nd Long COVID Case Study and Launches Website for Physicians and Pediatricians to Indicate Interest in Participating in Tollovid Long COVID Clinical Study
Press Release | 04/20/2022
New York, NY, and Tel Aviv, ISRAEL, April 20, 2022 (GLOBE NEWSWIRE) -- via NewMediaWire -- Todos Medical, Ltd. (OTCQB: TOMDF), a comprehensive medical diagnostics and related solutions company, today announced that its majority-owned subsidiary 3CL Pharma, Ltd. is reporting a case study from Dr. Lee Morgentaler of a patient who used Tollovid®, the Company’s 3CL protease inhibitor dietary supplement immune support product, after experiencing Long COVID symptoms. Concurrent with this report, the Company launched a website for physicians and pediatricians to indicate their interest in participating in a Long COVID clinical study of Tollovid for their patients. Provided here is a link to the website for physicians to indicate their interest in participating: https://todosmedical.com/long-covid-physicians-case-study
“Recent efforts designed to help Long COVID patients fall short in two critical areas,” said Gerald Commissiong, President & CEO of Todos Medical. “Drug developers need a validated test to diagnose Long COVID patients, and need an approvable endpoint to run clinical trials. At this juncture, the medical community is only beginning to define Long COVID in patients, and validated clinical research tools needed to measure clinical benefit of interventions are lacking, although consensus is beginning to build in this area. We are seeing that case studies and anecdotal reports of benefit for patients with other approved 3CL protease inhibitors pave a way forward, however the inability to quickly change dosing and toxic side effects of those other products represent real barriers. We believe the societal impact we are seeing with Long COVID is just the tip of the iceberg, with direct impacts on GDP and workforce participation, which is why we cannot sit idly by and do nothing for this massive patient population when we believe clinical research into our 3CL protease inhibitor products is the right path forward. We hope the message being put forth by other clinical researchers that 3CL protease inhibition is a viable strategy resonates with physicians and patients alike, and that we galvanize the Long COVID community into action to help us advance clinical research of our products for the potential benefit to patients.”
LONG COVID CASE STUDY
ABSTRACT:
Post-Acute Sequelae of SARS-CoV-2 (PASC), or Long COVID, is a major public health problem. We report a case of breakthrough PASC and its resolution following a course of the 3CL protease inhibitor dietary supplement Tollovid®.
SUMMARIZED CASE REPORT:
A 33-year-old male in top physical shape presented COVID-19 like symptoms of fatigue and loss of short term memory in mid-March 2020. The patient is a personal trainer and EMT that was 5’6” and weighed in at 135lbs. He was in top physical shape before COVID-19 and was able to run 3 miles in 20 minutes, bench press 225 lbs., dead lift 415 lbs., and squat 300 lbs. He worked out at least 5 days a week and went hiking. He and his family had no underlying medical conditions or allergies. The most likely source of infection was from the gym. The first symptom was the unexplained inability to run or lift weights and some occasional sneezing. The second symptom of short term memory loss coupled with dizziness appeared a couple of days after fatigue set in. The patient gained 25 lbs. in the next two weeks thinking that food would help him get better. The feasting didn’t work and then the patient resorted to intermittent fasting to get back down to his starting weight. Constant fatigue and memory loss and dizziness persisted for almost two years.
Despite the fatigue, dizziness, and loss of short-term memory, the patient returned to work in June 2020. He was a private fitness trainer and could only do 2 sessions a week due to chest pains from exertion. There was no change in his condition until his second vaccination shot. He received the first Pfizer shot on April 14, 2021 without any side effects beyond his base line status. On May 5, 2021 he received his second Pfizer vaccination shot. Three weeks later he was hospitalized for chest pain and an inability to breath. The patient believed that this was post vaccine injury. Once in the hospital, tests were done on his EKG and blood and consistent with his baseline before contracting his first case of COVID-19. The hospital did not administer a COVID-19 test. His symptoms after the three-day hospital stay were fatigue, dizziness, and memory loss.
In October 2021 the patient believes he contracted the Delta Variant. His wife tested COVID-19 positive and he had COVID-19-like symptoms of vomiting, diarrhea, coughing, worse fatigue, joint pain, and erectile dysfunction. One week after contracting COVID-19 he experienced left quadrant pain in his abdomen and successfully treated it with a colon rinse. His primary symptoms of fatigue, short-term memory loss, joint pain, and erectile dysfunction persisted.
The patient started a regimen of Tollovid Daily on February 14, 2022. He took 2 Tollovid Daily capsules for 30 days, but his symptoms completely resolved in 3 days. His baseline on February 14, 2022 consisted of being able to work out 2 times per week, but continued to suffer from fatigue, memory loss, joint pain, and erectile dysfunction. He was unable to do simple things like walking his dog. After 3 days of treatment his fatigue subsided, his memory improved, the joint pain dissipated, and his erectile dysfunction was resolved. He returned to his baseline routine of working out 5 times a week and taking his 2 year-old dog for walks. He no longer is treating himself for any Long COVID symptoms.
DISCUSSION
This case study reveals that even a small dosage of Tollovid Daily could be used to treat Long COVID. Given the quick and durable result more studies should be investigated in Long COVID. A major weakness of the study is the absence of a PCR positive COVID-19 test. The interesting part of this case study is related to the apparent vaccine injury that the patient suffered through. It has been documented in journal articles that a vaccine given during active COVID-19 infection could result in more severe disease. The presence of Long COVID followed by the second vaccination seems to support the theory that some cases of Long COVID are due to viral persistence. The delayed onset of the vaccine injury can be explained by low viral levels of viral persistence followed by a cytokine storm that led to hospitalization. The quick rebound to the pre-COVID baseline suggests that Tollovid was able to have a durable impact on the patient.
Disclaimer: Tollovid® and Tollovid Daily™ are 3CL protease inhibitor dietary supplement immune support products, and are not approved by the US FDA to diagnose, treat, prevent or cure any disease, including COVID-19 and/or Long COVID (Post-Acute Sequalae of COVID, or “PASC”).
About Tollovid®
Tollovid is a dietary supplement product made from natural ingredients that help support and maintain healthy immune function and also has potent 3CL protease inhibition properties based upon in vitro functional assays that show strong inhibition of 3CL protease activity. Tollovid's 3CL protease IC50 binding affinity is at least ten times as strong as Ivermectin’s published 3CL protease IC50 binding affinity. Tollovid binds to the active site (receptor binding domain) of the 3CL protease. Tollovid has a 5-day dosing regimen, with 4 doses of 3 pills taken each day that provides maximum immune support.
About Tollovir®
Tollovir® is a 3CL protease inhibitor and anti-cytokine therapeutic candidate for the treatment of the nidovirus subcategory of coronaviruses that includes SARS-CoV-2, COVID-19, SARS-CoV-1, MERS and 229E. Tollovir is made from all natural ingredients that are qualified to ensure strong inhibition of the 3CL protease in vitro, as well as strong anti-cytokine activity. Tollovir is currently in a Phase 2 clinical trial in Israel for the treatment of patients hospitalized with COVID-19. Tollovir will be developed for the treatment of hospitalized COVID-19 (severe and critical), moderate COVID-19, long-haul COVID and potentially pediatric COVID-19. Todos has licensed rights for Tollovir to T-Cell Protect Hellas S.A. for the Greek market.
About Todos Medical Ltd.
Founded in Rehovot, Israel with offices in New York City, Todos Medical Ltd. (OTCQB: TOMDF) engineers’ life-saving diagnostic solutions for the early detection of a variety of cancers. The Company's state-of-the-art and patented Todos Biochemical Infrared Analyses (TBIA) is a proprietary cancer-screening technology using peripheral blood analysis that deploys deep examination into cancer's influence on the immune system, looking for biochemical changes in blood mononuclear cells and plasma. Todos’ two internally developed cancer-screening tests, TMB-1 and TMB-2 have received a CE mark in Europe. Todos recently acquired U.S.-based medical diagnostics company Provista Diagnostics, Inc. to gain rights to its Alpharetta, Georgia-based CLIA/CAP certified lab currently performing PCR COVID testing and Provista's proprietary commercial-stage Videssa® breast cancer blood test.
Todos is also developing blood tests for the early detection of neurodegenerative disorders, such as Alzheimer's disease. The Lymphocyte Proliferation Test (LymPro Test™) is a diagnostic blood test that determines the ability of peripheral blood lymphocytes (PBLs) and monocytes to withstand an exogenous mitogenic stimulation that induces them to enter the cell cycle. It is believed that certain diseases, most notably Alzheimer's disease, are the result of compromised cellular machinery that leads to aberrant cell cycle re-entry by neurons, which then leads to apoptosis. LymPro is unique in the use of peripheral blood lymphocytes as a surrogate for neuronal cell function, suggesting a common relationship between PBLs and neurons in the brain.
Todos has entered into distribution agreements with companies to distribute certain novel coronavirus (COVID-19) test kits. The agreements cover multiple international suppliers of PCR testing kits and related materials and supplies, as well as antibody testing kits from multiple manufacturers after completing validation of said testing kits and supplies in its partner CLIA/CAP certified laboratory in the United States. Additionally, Todos has entered into a joint venture with NLC Pharma to pursue the development of diagnostic tests targeting the 3CL protease, as well as 3CL protease inhibitors that target a fundamental reproductive mechanism of coronaviruses.
For more information, please visit https://www.todosmedical.com/.
Forward-looking Statements
Certain statements contained in this press release may constitute forward-looking statements. For example, forward-looking statements are used when discussing our expected clinical development programs and clinical trials. These forward-looking statements are based only on current expectations of management, and are subject to significant risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements, including the risks and uncertainties related to the progress, timing, cost, and results of clinical trials and product development programs; difficulties or delays in obtaining regulatory approval or patent protection for product candidates; competition from other biotechnology companies; and our ability to obtain additional funding required to conduct our research, development and commercialization activities. In addition, the following factors, among others, could cause actual results to differ materially from those described in the forward-looking statements: changes in technology and market requirements; delays or obstacles in launching our clinical trials; changes in legislation; inability to timely develop and introduce new technologies, products and applications; lack of validation of our technology as we progress further and lack of acceptance of our methods by the scientific community; inability to retain or attract key employees whose knowledge is essential to the development of our products; unforeseen scientific difficulties that may develop with our process; greater cost of final product than anticipated; loss of market share and pressure on pricing resulting from the competition; and laboratory results that do not translate to equally good results in real settings, all of which could cause the actual results or performance to differ materially from those contemplated in such forward-looking statements. Except as otherwise required by law, Todos Medical does not undertake any obligation to publicly release any revisions to these forward-looking statements to reflect events or circumstances after the date hereof or to reflect the occurrence of unanticipated events. For a more detailed description of the risks and uncertainties affecting Todos Medical, please refer to its reports filed from time to time with the U.S. Securities and Exchange Commission.
Todos Corporate Contact:
Daniel Hirsch
CFO
Todos Medical
917-983-4229 x 104
Dan.h@todosmedical.com
Todos Investor Relations Contact:
Eric Ribner
LifeSci Advisors
Email: eric@lifesciadvisors.com
$TOMDF News!
Todos Medical Reports 2nd Long COVID Case Study and Launches Website for Physicians and Pediatricians to Indicate Interest in Participating in Tollovid Long COVID Clinical Study
Press Release | 04/20/2022
New York, NY, and Tel Aviv, ISRAEL, April 20, 2022 (GLOBE NEWSWIRE) -- via NewMediaWire -- Todos Medical, Ltd. (OTCQB: TOMDF), a comprehensive medical diagnostics and related solutions company, today announced that its majority-owned subsidiary 3CL Pharma, Ltd. is reporting a case study from Dr. Lee Morgentaler of a patient who used Tollovid®, the Company’s 3CL protease inhibitor dietary supplement immune support product, after experiencing Long COVID symptoms. Concurrent with this report, the Company launched a website for physicians and pediatricians to indicate their interest in participating in a Long COVID clinical study of Tollovid for their patients. Provided here is a link to the website for physicians to indicate their interest in participating: https://todosmedical.com/long-covid-physicians-case-study
“Recent efforts designed to help Long COVID patients fall short in two critical areas,” said Gerald Commissiong, President & CEO of Todos Medical. “Drug developers need a validated test to diagnose Long COVID patients, and need an approvable endpoint to run clinical trials. At this juncture, the medical community is only beginning to define Long COVID in patients, and validated clinical research tools needed to measure clinical benefit of interventions are lacking, although consensus is beginning to build in this area. We are seeing that case studies and anecdotal reports of benefit for patients with other approved 3CL protease inhibitors pave a way forward, however the inability to quickly change dosing and toxic side effects of those other products represent real barriers. We believe the societal impact we are seeing with Long COVID is just the tip of the iceberg, with direct impacts on GDP and workforce participation, which is why we cannot sit idly by and do nothing for this massive patient population when we believe clinical research into our 3CL protease inhibitor products is the right path forward. We hope the message being put forth by other clinical researchers that 3CL protease inhibition is a viable strategy resonates with physicians and patients alike, and that we galvanize the Long COVID community into action to help us advance clinical research of our products for the potential benefit to patients.”
LONG COVID CASE STUDY
ABSTRACT:
Post-Acute Sequelae of SARS-CoV-2 (PASC), or Long COVID, is a major public health problem. We report a case of breakthrough PASC and its resolution following a course of the 3CL protease inhibitor dietary supplement Tollovid®.
SUMMARIZED CASE REPORT:
A 33-year-old male in top physical shape presented COVID-19 like symptoms of fatigue and loss of short term memory in mid-March 2020. The patient is a personal trainer and EMT that was 5’6” and weighed in at 135lbs. He was in top physical shape before COVID-19 and was able to run 3 miles in 20 minutes, bench press 225 lbs., dead lift 415 lbs., and squat 300 lbs. He worked out at least 5 days a week and went hiking. He and his family had no underlying medical conditions or allergies. The most likely source of infection was from the gym. The first symptom was the unexplained inability to run or lift weights and some occasional sneezing. The second symptom of short term memory loss coupled with dizziness appeared a couple of days after fatigue set in. The patient gained 25 lbs. in the next two weeks thinking that food would help him get better. The feasting didn’t work and then the patient resorted to intermittent fasting to get back down to his starting weight. Constant fatigue and memory loss and dizziness persisted for almost two years.
Despite the fatigue, dizziness, and loss of short-term memory, the patient returned to work in June 2020. He was a private fitness trainer and could only do 2 sessions a week due to chest pains from exertion. There was no change in his condition until his second vaccination shot. He received the first Pfizer shot on April 14, 2021 without any side effects beyond his base line status. On May 5, 2021 he received his second Pfizer vaccination shot. Three weeks later he was hospitalized for chest pain and an inability to breath. The patient believed that this was post vaccine injury. Once in the hospital, tests were done on his EKG and blood and consistent with his baseline before contracting his first case of COVID-19. The hospital did not administer a COVID-19 test. His symptoms after the three-day hospital stay were fatigue, dizziness, and memory loss.
In October 2021 the patient believes he contracted the Delta Variant. His wife tested COVID-19 positive and he had COVID-19-like symptoms of vomiting, diarrhea, coughing, worse fatigue, joint pain, and erectile dysfunction. One week after contracting COVID-19 he experienced left quadrant pain in his abdomen and successfully treated it with a colon rinse. His primary symptoms of fatigue, short-term memory loss, joint pain, and erectile dysfunction persisted.
The patient started a regimen of Tollovid Daily on February 14, 2022. He took 2 Tollovid Daily capsules for 30 days, but his symptoms completely resolved in 3 days. His baseline on February 14, 2022 consisted of being able to work out 2 times per week, but continued to suffer from fatigue, memory loss, joint pain, and erectile dysfunction. He was unable to do simple things like walking his dog. After 3 days of treatment his fatigue subsided, his memory improved, the joint pain dissipated, and his erectile dysfunction was resolved. He returned to his baseline routine of working out 5 times a week and taking his 2 year-old dog for walks. He no longer is treating himself for any Long COVID symptoms.
DISCUSSION
This case study reveals that even a small dosage of Tollovid Daily could be used to treat Long COVID. Given the quick and durable result more studies should be investigated in Long COVID. A major weakness of the study is the absence of a PCR positive COVID-19 test. The interesting part of this case study is related to the apparent vaccine injury that the patient suffered through. It has been documented in journal articles that a vaccine given during active COVID-19 infection could result in more severe disease. The presence of Long COVID followed by the second vaccination seems to support the theory that some cases of Long COVID are due to viral persistence. The delayed onset of the vaccine injury can be explained by low viral levels of viral persistence followed by a cytokine storm that led to hospitalization. The quick rebound to the pre-COVID baseline suggests that Tollovid was able to have a durable impact on the patient.
Disclaimer: Tollovid® and Tollovid Daily™ are 3CL protease inhibitor dietary supplement immune support products, and are not approved by the US FDA to diagnose, treat, prevent or cure any disease, including COVID-19 and/or Long COVID (Post-Acute Sequalae of COVID, or “PASC”).
About Tollovid®
Tollovid is a dietary supplement product made from natural ingredients that help support and maintain healthy immune function and also has potent 3CL protease inhibition properties based upon in vitro functional assays that show strong inhibition of 3CL protease activity. Tollovid's 3CL protease IC50 binding affinity is at least ten times as strong as Ivermectin’s published 3CL protease IC50 binding affinity. Tollovid binds to the active site (receptor binding domain) of the 3CL protease. Tollovid has a 5-day dosing regimen, with 4 doses of 3 pills taken each day that provides maximum immune support.
About Tollovir®
Tollovir® is a 3CL protease inhibitor and anti-cytokine therapeutic candidate for the treatment of the nidovirus subcategory of coronaviruses that includes SARS-CoV-2, COVID-19, SARS-CoV-1, MERS and 229E. Tollovir is made from all natural ingredients that are qualified to ensure strong inhibition of the 3CL protease in vitro, as well as strong anti-cytokine activity. Tollovir is currently in a Phase 2 clinical trial in Israel for the treatment of patients hospitalized with COVID-19. Tollovir will be developed for the treatment of hospitalized COVID-19 (severe and critical), moderate COVID-19, long-haul COVID and potentially pediatric COVID-19. Todos has licensed rights for Tollovir to T-Cell Protect Hellas S.A. for the Greek market.
About Todos Medical Ltd.
Founded in Rehovot, Israel with offices in New York City, Todos Medical Ltd. (OTCQB: TOMDF) engineers’ life-saving diagnostic solutions for the early detection of a variety of cancers. The Company's state-of-the-art and patented Todos Biochemical Infrared Analyses (TBIA) is a proprietary cancer-screening technology using peripheral blood analysis that deploys deep examination into cancer's influence on the immune system, looking for biochemical changes in blood mononuclear cells and plasma. Todos’ two internally developed cancer-screening tests, TMB-1 and TMB-2 have received a CE mark in Europe. Todos recently acquired U.S.-based medical diagnostics company Provista Diagnostics, Inc. to gain rights to its Alpharetta, Georgia-based CLIA/CAP certified lab currently performing PCR COVID testing and Provista's proprietary commercial-stage Videssa® breast cancer blood test.
Todos is also developing blood tests for the early detection of neurodegenerative disorders, such as Alzheimer's disease. The Lymphocyte Proliferation Test (LymPro Test™) is a diagnostic blood test that determines the ability of peripheral blood lymphocytes (PBLs) and monocytes to withstand an exogenous mitogenic stimulation that induces them to enter the cell cycle. It is believed that certain diseases, most notably Alzheimer's disease, are the result of compromised cellular machinery that leads to aberrant cell cycle re-entry by neurons, which then leads to apoptosis. LymPro is unique in the use of peripheral blood lymphocytes as a surrogate for neuronal cell function, suggesting a common relationship between PBLs and neurons in the brain.
Todos has entered into distribution agreements with companies to distribute certain novel coronavirus (COVID-19) test kits. The agreements cover multiple international suppliers of PCR testing kits and related materials and supplies, as well as antibody testing kits from multiple manufacturers after completing validation of said testing kits and supplies in its partner CLIA/CAP certified laboratory in the United States. Additionally, Todos has entered into a joint venture with NLC Pharma to pursue the development of diagnostic tests targeting the 3CL protease, as well as 3CL protease inhibitors that target a fundamental reproductive mechanism of coronaviruses.
For more information, please visit https://www.todosmedical.com/.
Forward-looking Statements
Certain statements contained in this press release may constitute forward-looking statements. For example, forward-looking statements are used when discussing our expected clinical development programs and clinical trials. These forward-looking statements are based only on current expectations of management, and are subject to significant risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements, including the risks and uncertainties related to the progress, timing, cost, and results of clinical trials and product development programs; difficulties or delays in obtaining regulatory approval or patent protection for product candidates; competition from other biotechnology companies; and our ability to obtain additional funding required to conduct our research, development and commercialization activities. In addition, the following factors, among others, could cause actual results to differ materially from those described in the forward-looking statements: changes in technology and market requirements; delays or obstacles in launching our clinical trials; changes in legislation; inability to timely develop and introduce new technologies, products and applications; lack of validation of our technology as we progress further and lack of acceptance of our methods by the scientific community; inability to retain or attract key employees whose knowledge is essential to the development of our products; unforeseen scientific difficulties that may develop with our process; greater cost of final product than anticipated; loss of market share and pressure on pricing resulting from the competition; and laboratory results that do not translate to equally good results in real settings, all of which could cause the actual results or performance to differ materially from those contemplated in such forward-looking statements. Except as otherwise required by law, Todos Medical does not undertake any obligation to publicly release any revisions to these forward-looking statements to reflect events or circumstances after the date hereof or to reflect the occurrence of unanticipated events. For a more detailed description of the risks and uncertainties affecting Todos Medical, please refer to its reports filed from time to time with the U.S. Securities and Exchange Commission.
Todos Corporate Contact:
Daniel Hirsch
CFO
Todos Medical
917-983-4229 x 104
Dan.h@todosmedical.com
Todos Investor Relations Contact:
Eric Ribner
LifeSci Advisors
Email: eric@lifesciadvisors.com
$TOMDF @ .0142!
$TOMDF @ .0142!
$NNRX @ .0006!
$NNRX @ .0005!
$NNRX @ .0004!
$NNRX @ .0004!
$NNRX @ .0003!
$NNRX @ .0003!
$JPEX @ .0156!
$JPEX @ .0156!
$JPEX @ .0149!
$ECEZ @ .0003!
$ECEZ @ .0003!
$ECEZ @ .0002!
$ECEZ @ .0002!
$WHEN @ .0005!
$WHEN @ .0005!
$NTPY @ .10!
$NTPY @ .10!
$NTPY @ .06!
$NTPY @ .06!
$Happy Thanksgiving Amigos!!!
God bless you all!!!
Psalms 28:7
Hugs,
Estrella
$RITT News!:
Nov 02, 2021
DOUBLE DELIGHT FOR DATA CENTRE MANAGEMENT PIONEERS
XpedITe, RiT Tech’s revolutionary approach to data centre infrastructure management, is continuing to earn rave reviews and recognition from industry insiders.
The cutting-edge Universal Intelligent Infrastructure Management solution secured a hotly-contested double at this year’s DCS Awards, which celebrates the achievements of businesses serving the global data centre sector and attracted nominations from hundreds of suppliers.
XpedITe was crowned Data Centre Intelligent Automation and Management Innovation of the Year and – for a second time in succession – Data Centre ICT Automation/Orchestration Innovation of the Year during the high-profile prize-giving ceremony in London.
The dual success follows the announcement that RiT Tech’s transformative technology has attracted financial backing from the Israel Innovation Authority that will be used to further advance its intelligent automation and predictive planning capabilities.
Powered by advanced algorithms and developed to remove operational blind spots from a data centre’s topology by capturing the role of every asset and its inter-dependencies, XpedITe already affords users a real-time, 360-degree view of their operations.
A significant step change from the monitoring capabilities of other Data Centre Infrastructure Management tools, it can plan installations and forecast risks, automate ongoing processes and operational workflows as well as manage the lifecycle of assets and resource utilisation.
Reflecting on the accolades received by XpedITe, RiT Tech CEO Assaf Sklonik said: “We are delighted to have been recognised by our peers – the DCS titles represent a reward for the team’s hard work and will to challenge convention.
“At RiT Tech we are on a mission to positively change the industries we operate in, to help make them more efficient for the benefit of society as a whole and these two awards are an endorsement that we remain firmly on track.”
https://www.rittech.com/double-delight-for-data-centre-management-pioneers
$RITT News!:
Nov 02, 2021
DOUBLE DELIGHT FOR DATA CENTRE MANAGEMENT PIONEERS
XpedITe, RiT Tech’s revolutionary approach to data centre infrastructure management, is continuing to earn rave reviews and recognition from industry insiders.
The cutting-edge Universal Intelligent Infrastructure Management solution secured a hotly-contested double at this year’s DCS Awards, which celebrates the achievements of businesses serving the global data centre sector and attracted nominations from hundreds of suppliers.
XpedITe was crowned Data Centre Intelligent Automation and Management Innovation of the Year and – for a second time in succession – Data Centre ICT Automation/Orchestration Innovation of the Year during the high-profile prize-giving ceremony in London.
The dual success follows the announcement that RiT Tech’s transformative technology has attracted financial backing from the Israel Innovation Authority that will be used to further advance its intelligent automation and predictive planning capabilities.
Powered by advanced algorithms and developed to remove operational blind spots from a data centre’s topology by capturing the role of every asset and its inter-dependencies, XpedITe already affords users a real-time, 360-degree view of their operations.
A significant step change from the monitoring capabilities of other Data Centre Infrastructure Management tools, it can plan installations and forecast risks, automate ongoing processes and operational workflows as well as manage the lifecycle of assets and resource utilisation.
Reflecting on the accolades received by XpedITe, RiT Tech CEO Assaf Sklonik said: “We are delighted to have been recognised by our peers – the DCS titles represent a reward for the team’s hard work and will to challenge convention.
“At RiT Tech we are on a mission to positively change the industries we operate in, to help make them more efficient for the benefit of society as a whole and these two awards are an endorsement that we remain firmly on track.”
https://www.rittech.com/double-delight-for-data-centre-management-pioneers
$RITT News:
Oct 18, 2021
A NEW DAWN FOR DCIM?
“It takes many good deeds to build a good reputation, and only one bad one to lose it.”
As one of the United States’ founding fathers, Benjamin Franklin may not be the most contemporary of reference points but his sage appraisal of the fragility of social standing still holds plenty of stock today.
Good news for those associated with unblemished brands, damning for those in the business of Data Centre Infrastructure Management (DCIM) – a much-maligned capability that has a decade’s worth of disappointment, rather than a single blot, on its copybook.
Mis-marketed, mis-sold and misunderstood, DCIM is frequently spoken of in derisory terms by industry insiders as a consequence of a substantial legacy of ineffective deployments, despite the concept being based on sound principles.
There is, however, a very real requirement for a Lazarus-style reputational recovery – for the loathed to become loved and mocked to become marvelled.
Data centres – and the sprawling IT estates they house – are becoming increasingly complex and hybrid in nature, which makes their effective management a feat far beyond the means of mere spreadsheets and asset registers.
The coronavirus pandemic has also given cause to reconsider the merits of deploying DCIM systems.
With sites sealed due to social-distancing measures and major restrictions on travel put in place during lockdowns, some data centres were not readily accessible to the humans carrying clipboards and manual management tools which are often relied on to sustain the healthy operations of facilities and cabling infrastructure.
Given the direction of travel within the sector is very much towards dark sites and the Edge, improved technology will soon be a necessity rather than a nice to have. Operators will need remote access to a single source of truth that considers the management, connectivity and automation of every element of the data centre ecosystem.
Whether or not reputations can be repaired remains to be seen, but stereotypes can shift and suppliers of fit-for-purpose DCIM systems should be buoyed by the example of a sector driving data centre capacity extension.
Rewind to the start of the current century and the term “gamer” conjured images of teenagers shunning natural light and social interaction in favour of fervent button bashing in their bedrooms.
Today, time in front of a console is as far removed as possible from being a solitary experience with people joining online games to actively mix with a global family of 2.8 billion people and powering an industry worth more than $175 billion.
Gaming has become a social monster and is community driven to the extent that people even enjoy watching others play – as evidenced by the professionalisation of e-sports and the millions who tune in to watch live-streamed finals.
Significant advancements in technology, specifically the sophistication of computer networks and speed of sharing data, have been at the spearhead of this reinvention and DCIM can follow suit.
There are now new players in the game with the ability to leapfrog legacy systems in terms of providing cheaper and easier to install systems that are dramatically less resource intensive from the human perspective.
The penny has also dropped that the “management” element of the DCIM moniker is critical and there is a general acceptance that tools which simply monitor are continuing to miss the point.
Optimising a data centre’s performance, mitigating downtime, driving efficiencies and planning for the future all require the mining of multiple data sets for the benefit of multiple stakeholders and consequently savvy suppliers, such as automation specialist RiT Tech, have brought interoperability to the fore.
An effective DCIM needs to act as the glue to bind a data centre’s many component parts and therefore augment – and not replace – specialist tools already in place through smart but quick to configure APIs.
Ultimately, perceptions will only be changed through positive experiences and the recent demise of Vertiv’s Trellis DCIM demonstrates the scale of the challenge at hand.
RiT Tech, however, remains undeterred from its mission to distance itself from DCIM’s dark past and plans to define a brighter future with its next-generation solution, XpedITe.
While Franklin’s words continue to ring true, RiT Tech have also noted those of Amazon founder and multi-billionaire Jeff Bezos… “you earn reputation by trying to do hard things well”.
https://www.rittech.com/a-new-dawn-for-dcim
$RITT News:
Oct 18, 2021
A NEW DAWN FOR DCIM?
“It takes many good deeds to build a good reputation, and only one bad one to lose it.”
As one of the United States’ founding fathers, Benjamin Franklin may not be the most contemporary of reference points but his sage appraisal of the fragility of social standing still holds plenty of stock today.
Good news for those associated with unblemished brands, damning for those in the business of Data Centre Infrastructure Management (DCIM) – a much-maligned capability that has a decade’s worth of disappointment, rather than a single blot, on its copybook.
Mis-marketed, mis-sold and misunderstood, DCIM is frequently spoken of in derisory terms by industry insiders as a consequence of a substantial legacy of ineffective deployments, despite the concept being based on sound principles.
There is, however, a very real requirement for a Lazarus-style reputational recovery – for the loathed to become loved and mocked to become marvelled.
Data centres – and the sprawling IT estates they house – are becoming increasingly complex and hybrid in nature, which makes their effective management a feat far beyond the means of mere spreadsheets and asset registers.
The coronavirus pandemic has also given cause to reconsider the merits of deploying DCIM systems.
With sites sealed due to social-distancing measures and major restrictions on travel put in place during lockdowns, some data centres were not readily accessible to the humans carrying clipboards and manual management tools which are often relied on to sustain the healthy operations of facilities and cabling infrastructure.
Given the direction of travel within the sector is very much towards dark sites and the Edge, improved technology will soon be a necessity rather than a nice to have. Operators will need remote access to a single source of truth that considers the management, connectivity and automation of every element of the data centre ecosystem.
Whether or not reputations can be repaired remains to be seen, but stereotypes can shift and suppliers of fit-for-purpose DCIM systems should be buoyed by the example of a sector driving data centre capacity extension.
Rewind to the start of the current century and the term “gamer” conjured images of teenagers shunning natural light and social interaction in favour of fervent button bashing in their bedrooms.
Today, time in front of a console is as far removed as possible from being a solitary experience with people joining online games to actively mix with a global family of 2.8 billion people and powering an industry worth more than $175 billion.
Gaming has become a social monster and is community driven to the extent that people even enjoy watching others play – as evidenced by the professionalisation of e-sports and the millions who tune in to watch live-streamed finals.
Significant advancements in technology, specifically the sophistication of computer networks and speed of sharing data, have been at the spearhead of this reinvention and DCIM can follow suit.
There are now new players in the game with the ability to leapfrog legacy systems in terms of providing cheaper and easier to install systems that are dramatically less resource intensive from the human perspective.
The penny has also dropped that the “management” element of the DCIM moniker is critical and there is a general acceptance that tools which simply monitor are continuing to miss the point.
Optimising a data centre’s performance, mitigating downtime, driving efficiencies and planning for the future all require the mining of multiple data sets for the benefit of multiple stakeholders and consequently savvy suppliers, such as automation specialist RiT Tech, have brought interoperability to the fore.
An effective DCIM needs to act as the glue to bind a data centre’s many component parts and therefore augment – and not replace – specialist tools already in place through smart but quick to configure APIs.
Ultimately, perceptions will only be changed through positive experiences and the recent demise of Vertiv’s Trellis DCIM demonstrates the scale of the challenge at hand.
RiT Tech, however, remains undeterred from its mission to distance itself from DCIM’s dark past and plans to define a brighter future with its next-generation solution, XpedITe.
While Franklin’s words continue to ring true, RiT Tech have also noted those of Amazon founder and multi-billionaire Jeff Bezos… “you earn reputation by trying to do hard things well”.
https://www.rittech.com/a-new-dawn-for-dcim