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Everyone is also forgetting we have more Leukimia data this year in 2013. the trial for CML went well as 14 of 14 subjects had antibody responses to the leukimia with the inovio vaccine. So they went ahead and enrolled the Acute Myloid Leukimia arm patients(more severe to treat) and the results we shall see this year should be good. They will probably show BCR-ABL in CML and time to disease progression in AML possibly.
http://ir.inovio.com/2012-12-06-Inovio-Pharmaceuticals-Announces-Positive-Interim-Results-in-Phase-II-Leukemia-Trial
The problem is that many don't want to gamble and many don't see the true value in the stock. I bet you not many predicted or cared to notice PCYC trading at $1 a share back in 2009 and today PCYC trades at $77.94. when people back then saw the big pipeline that PCYC had and trading only at $1 a share why didn't they buy?? Not too many people did their DD and many missed a huge opportunity.
INO with it's big pipeline now is undervalued but as soon as phase 2 results fall into positive place the company will be revalued higher and I will dare to say that INO in the next 4 to 5 years will be trading $75+ like PCYC!
I hope you are right Farne! I have been waiting for judgement day!
did you see the last 20 min in volume? Big buys at the end to bring INO up higher. Someone seems to accumulate shares at the end of the day!
I agree nice volume. 2 things to discuss
1.) what is up with all the 100 share buy/sell blocks throughout the entire day? do we have a machine trading our stock?
2. ) 2nd I spoke to the guy at stocktwits and they claimed that once INO is over $1 again they will see if they bring it back. Doubtful but we shall see!
Happy investing INO investors!
I don't know as I'm not sure about Chrontechs schedule. But it's possible that results may be delayed for a week or so. Personally Id rather get hep C news this week so that the HIV news can come before biocentury conference!
Check this out guys. What's up with the 100 share block buys at .55 cents for INO. Is it being held down so they can accumulate at that price?
http://www.nasdaq.com/symbol/ino/time-sales#.UVBTyxd9BUV
Typical bear raid pre market by money managers to shake out retail investors. No matter I'm holding long, they probably know good news is coming and want all the shares they can get! INO is poised for greatness within the next 2 weeks!
I saw that video and I agree I think it does have to do with INO. I say this because INO is presenting at the Biocentury conference coming up April 5th Friday. Also INO expects to publish its phase 1 HIV in medical journal before then possibly. Good times are coming for INO. The buy from insiders and the 2 new funds that bought in has me optimistic that INO will skyrocket soon!
hepatitis C is still expected 1st quarter 2013. Many people are iffy on this because we only have one week left so don't know if there will be a small delay. Also HIV pennvax B therapeutic completed phase 1 and article has been sent to a publishing medical journal to publish the phase 1 results.
in 1st half 2013 expected:
influenza data
pandemic flu data
2013 expected :
Begin phase 1 HIV for pennvax GP
Begin phase 1 prostate cancer
More phase 2 Leukimia data, this time they will show BCR-ABL and other stuff
2nd half 2013:
Begin phase 1 for hepatitis C but not Chrontech's. This time it's INO's hep C drug INO-8000 and it doesn't use Standard of care like chronvac C. It will just be the vaccine with electropration alone targeting both genotype 1a and 1b hep c.
1st half 2014:
Begin phase 1 testing of Malaria vaccine
Phase 2 data for Cervical cancer out
Possiblities:
This is iffy but possible partnership on a pre clinical product is possible. CEO mentioned that INO is in pre clinical work on lung cancer vaccine and breast cancer vaccine. So that remains to be seen! GL to all
After hours is just smoke and mirrors and volume is small. I would wait for pre market monday to see which direction it will go!
yep Angel Cabrera director bought 40,000 shares just posted 10 mins ago. so we have the CEO, COO, CFO, director etc. all buying more shares this week. Plus we had Heights capital management buying in, and now after hours FXM funds mutual growth fund buying. This to me indicates fantastic results are coming!
I agree Kim bought yesterday 60,000 shares and the COO Niranjan Sardesai bought 25,000 shares today. Looks like we have good data next week and this will easily go up to $1 +
Farne no worries man. Let's use this board in the meantime . They call it a penny stock because it's under $1 but they don't know the true value of the stock and pipeline. INO has hep C phase 2 interim data and then HIV in medical journal and once those are out we will easily see $2 + easy!
Between they are not the brightest how can INO be considered a penny stock when it doesn't trade on the OTC BB. It trades on a big exchange the NYSE is a big exchange. As being professional investors they should know the difference between a penny stock and a higher level stock. I'm saddened by the CEO responses totally unprofessional and unethical.
Welcome Mario We have no choice really. Apparently our stream was worth shutting down. LOL. Anyways INO still shows on website for Hep C phase 2 data in Q1 2013 and I think that HIV phase I pennvax B should be out early April. GL to All.
I agree but there is nothing we can do about it. I guess we have this nice board here :) btw I am biopharmapro on stocktwits. INO will rise above $1 soon anyways and we will hopefully get our stream back.
You can still post on there but it doesn't stream up. Also someone said they called the office there and was told that too much manipulation was going on INO stream so they stopped it.
Stocktwits has stopped the stream on INO. They said the stock is easily manipulated and that's why they shut it down. yet all other OTC stocks on stocktwits can still stream. They can censor our voices but they will never take away our freedom to buy INO!
In essence from my previous posting I think they are trying to avoid a hostile take out bid. Lets say they don't enact this then any big pharma company BMY, Merck, Pfizer can come in and do a hostile takeover and buy the company out. I mean it trades at .50 cents a share and if results come out good, then what is to stop a big pharma from doing a hostile takeover??? With the extra authorized shares they can add them in and increase the takeout price in the event that happens and stop takeout bids. Do you see why they are doing this now??? Smart scientists and smart management team they think ahead.
So everyone knows that the authorized shares just means for them to enact them when they need too. They won't dilute that many shares right away. They will enact it only when they need too that's for starters.
Secondly I did some research and I think management should do it and after you read this you will know why it is a good idea to vote yes when they vote on it, I know I will vote yes. Read this:
"The Board believes the Amendment is advisable and in the best interests of the Company and our stockholders to make available for future issuance a sufficient number of authorized shares of common stock to give us appropriate flexibility to issue shares for future corporate needs.
As discussed under “Potential Effects of the Amendment” below, additional shares could be issued to oppose a hostile takeover attempt or delay or prevent changes in control of the Company or could be reserved as part of an anti-takeover strategy or in connection with a stockholder rights plan. The additional authorized shares would also provide us with increased financing and capital raising flexibility and could be used for other business and financial purposes that the Board deems are in the Company’s best interest, including the acquisition of other companies, businesses or products in exchange for common stock, attraction and retention of employees through the issuance of additional securities under our equity incentive plans, implementation of stock splits and issuance of dividends in the future and delay or prevent changes in control of the Company. Without an increase in the number of authorized shares of common stock, the Company may be constrained in its ability to raise capital, should the need arise, and may lose important business opportunities, including to competitors, which could adversely affect our financial performance and growth.
The additional authorized shares of common stock would enable us to act quickly in response to capital raising and other corporate opportunities that may arise (as described above), in most cases without the necessity of holding a special stockholders’ meeting and obtaining further stockholder approval before the issuance of common stock could proceed, except as may be required by applicable law or the rules of NYSE MKT or any other stock exchange on which our securities may be listed."
Management must be really confident. 4 insiders CEO , CFO, COO, and CMO all bought 180,000 options each starting from 2013 all the way out to 2015. Do they know something we don't? good times are ahead my friends! Like I said patience wins in the end when your investing, Day trading is just a mirage.
thank you Alex for the link my man. I hope more people realize how good INO is instead of continously bashing it. Thank you for this!
I told people about a website that showed all the information about RXII and it has lots of other good biotech stock picks for portfolios. Long and strong RXII! http://bioresearchxtra-com1.webs.com/
I think that PPHM is still a good long term play and we should be getting some new data soon on the other phase 2 drugs in the pipeline. Still a good long term buy! http://bioresearchxtra-com1.webs.com/
Yep thanks man, also here is an article just put out on yahoo finance from Wall street journal with video! http://blogs.wsj.com/digits/2013/02/19/qa-inovio-ceo-on-dna-vaccines/?mod=yahoo_hs
RXI has a phase I trial results ongoing for scarring and I think it can be huge. Check out this person's website that I found to be interesting! http://bioresearchxtra-com1.webs.com/
Check out this guys website that shows some good DD on Advaxis! http://bioresearchxtra-com1.webs.com/
No problem I have done well with ARNA in the past when I bought it at 1.79 a share and sold at $11. Also I have told people to get into Advaxis which is another good vaccine company. For INO it's my biggest holdings because Inovio has everything going for themselves.
1. Good management and scientists on the scientific advisory board
2. 400 patents current and pending
3. own the rights to electroporation technology
4. Best T-cell responses shown to date in vaccines
if we are patient and can take these small hurdles I think people will be greatly rewarded.
Inovio has Hepatitis C results coming out this quarter I think once the results are out INO will double in value, 2013 is gonna be the best year yet for INO! http://bioresearchxtra-com1.webs.com/
Advaxis has results on CIN 2/3 cervical cancer coming up for the mide Dose I think the results are gonna be great thus the run up thus far! http://bioresearchxtra-com1.webs.com/
AM I misinterpreting things? or did INO just get an upgrade from Reuters today? Can anyone find a link and provide thanks? Anyways lets hope so that would make it 2 upgrades so far and lots of catlysts on the way INO is ready for take off!
A good article out today Jan 28th About Inovio!
Pennsylvania-based biotech Inovio is taking a different approach to developing a universal vaccine. Instead of inoculating people with an inactivated virus fragment or protein, the company is developing a DNA-based vaccine. To make it protective against multiple flu strains, the company combines DNA sequences from existing virus strains into a single dose. The DNA pieces are delivered by a shot combined with the company’s proprietary delivery system. A handheld device that looks like a pen delivers a small electric field which temporarily opens up cell membranes to allow the DNA vaccine to enter cells, says Inovio CEO Joseph Kim. Once inside cells, the DNA is read by the cell’s own machinery to build viral proteins which will activate the body’ immune system. The result is that the body creates antibodies against a diversity of flu strains.
The company is currently testing the vaccine in people 65 and older as a combination treatment along with existing flu vaccines. The elderly are the most at risk when it comes to flu and are the least protected by current immunizations. Every year, some 35,000 people die because of the flu and “90 percent of the deaths are in people who are 65 and older,” says Kim. “But the seasonal flu vaccine only protects about 10 to 20 percent of the elderly.”
Inovio’s clinical trial has shown that combining the seasonal flu vaccine with the company’s experimental universal vaccine has doubled the number of elderly protected from the flu.
“It is hard to predict the future, but if we can have a universal vaccine that can protect against all known dominant strains, the likelihood of protecting against future unknown is much higher,” says Kim. “If we are correct, we can change the flu paradigm into one more like what we do with other vaccinations.”
http://www.technologyreview.com/news/510316/why-the-flu-is-so-relentless-and-how-technology-might-help/
Adverse events will always happen but with Inovio it's minimal because Inovio uses Water (H2O) , which is safe for humans, and DNA antigens which doesn't produce problems like viral vectors and viruses grown in eggs. So I think with the huge safety profile and the good efficacy results we have seen I think INO is poised for long term success.
Yep Chrontech pharma up 110% , Im guessing good data leak on Hep C phase 2 results time for INO to go to the moon today! People will reevaluate INO now and the stock will jump!
Two important things this week for INO.
1. First INO is presenting tomorrow at the Noble financial capital markets Tuesday Jan 21st at 11:00 a.m. EST time
2. Second Chrontech has a meeting notes at the end of the week on Friday Jan 25th and as someone else pointed out the 12 weeks from last patient for Hep C is finished so possible results this week for Hep C phase 2.
Shorts are gonna be fried this week!
Get ready for more upside Piper Jeffray initiates INO at overweight with price target $1
here is the link for insider buying shares of INO! http://ih.advfn.com/p.php?pid=nmona&article=55875079
Director Collins of INO an insiders yesterday on Jan 15th bought 100,000 shares for his Grandchildren's trust funds. 50,000 shares each child! When you have good results on the way, partnerships and insider buying I don't know why anyone would be selling honestly!
Another INO press release: http://finance.yahoo.com/news/inovio-pharmaceuticals-initiate-clinical-trial-090000907.html "Inovio Pharmaceuticals to Initiate Clinical Trial for its Hepatitis C Therapeutic Vaccine (INO-8000) Later this Year"
INO announces partnership with PATH MVI for Malaria vaccine trials to begin in 2014 and to inject DNA vaccine in 30 trial patients and purposely infect those patients with mosquitoes that contain Malaria, that's how confident they are in the vaccine to work!