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It's the factual data of the AD trial that conclude an astonishingly positive outcome, where patients have functionally IMPROVED!
It's rather dubious how FUDsters continue to neglect and discount the successful results... Don't you, Dr. FUD?
ANAVEX®2-73 (blarcamesine) Meets Co-Primary and Key Secondary Endpoints for Patients with Early Alzheimer’s Disease
• Odds Ratio of ADAS-Cog meaningful improvement in cognition at threshold of -0.5 points or less (90% CI) 1.839 (1.17, 2.94) P = 0.015
• Odds Ratio of ADCS-ADL meaningful improvement in function at threshold of +3.5 points or higher (90% CI) 2.67 (1.17, 6.13) P = 0.0255
• ANAVEX®2-73 treatment slowed cognitive decline by 45% compared to placebo at 48 weeks
• Mean difference in ADAS-Cog score change of -1.85 points
• Compared to placebo, ANAVEX®2-73 (blarcamesine) reduced clinical decline of cognition and function by 27% with mean score difference of -0.42 points (p=0.040) as measured by CDR-SB
LOL... We all know that the pump up to $30, based on successful trial results, was helped by the same collusive manipulators that brought the price back down again. It's one and the same organized HF/MM cabal... you know, your handlers.
Nice try... The many successful trials weren't the reason for the stock price retrace from $30. We know and you know it is collusive manipulation... and it'll continue until approvals come next year.
Your FUD is wearing thin!
The history of the company is one successful trial after the next! They are working on NDA filings, partnerships and preparing for WW commercialization.
More baseless nonsensical FUD from you. It's rather pathetic.
Folks... this is nothing but organized collusive manipulation. You can tell by all the FUD that the usual characters start spewing in concert with the manipulated takedown. This is what they do before news comes... shake the tree hard to run stop-loss orders and get retail to sell.
They know their time is running out. This will recover, and then some, within a week or two.
Frequent wash trading of 50k sharers between HFT computers can give the illusion of volume.
I clearly stated that the runup was pure manipulation... as a setup for AF's timely pre-written hit piece. Textbook collusive cabal manipulation to bring it all the way back down.
Pocketing $1.00-1.70/share on a reload is never a bad thing. Tell your handlers 'thanks' for me, especially AF for the tipoff.
LOL... Your comments reflect FUDality!
That's hilarious... message to self.
You're like the board seagull... flies in occasionally, squawks nonsense, schits everywhere, then flies off.
That's special... colleague FUD support.
FYI... though you're unable to see it, the Partex partnership is quite strategic.
My group has been waiting for this time to load up... getting close.
No... it's your lame FUD that's DOA.
From this dismal report regarding clinicaltrials.gov updates (or lack thereof), seems Anavex is well above average in its reporting and updates.
Hey FUDman, those are the undeniable facts of the trial!
FUDsters stating baseless nonsense prompts me to repost the facts...
ANAVEX®2-73 (blarcamesine) Meets Co-Primary and Key Secondary Endpoints for Patients with Early Alzheimer’s Disease
• Odds Ratio of ADAS-Cog meaningful improvement in cognition at threshold of -0.5 points or less (90% CI) 1.839 (1.17, 2.94) P = 0.015
• Odds Ratio of ADCS-ADL meaningful improvement in function at threshold of +3.5 points or higher (90% CI) 2.67 (1.17, 6.13) P = 0.0255
• ANAVEX®2-73 treatment slowed cognitive decline by 45% compared to placebo at 48 weeks
• Mean difference in ADAS-Cog score change of -1.85 points
• Compared to placebo, ANAVEX®2-73 (blarcamesine) reduced clinical decline of cognition and function by 27% with mean score difference of -0.42 points (p=0.040) as measured by CDR-SB
plex, you're obviously unaware of the big collusive network out there. You don't think the Street knows about AF and the HFs/MMs he works for and what they do, their mission?
Why would any connected institution take a sizeable position before they need to? They'll know when the manipulation is about to end; therefore, they won't be initiating a position until that time. But when it starts to happen it'll be impressive.
If Anavex is the only biotech you follow, then you aren't seeing the other biotechs they target. It's not just Anavex.
I find it rather strange that we've had a very successful, likely pivotal, P3 AD trial, where all endpoints were met, with patients functionally improved, and yet some here are expressing higher confidence in Rett approval, when we haven't even seen the P3 results yet.
I certainly believe the Excellence results will also be quite good; however, to discount the astonishingly positive AD results seems rather odd... perhaps contrived.
It's rather clear Anavex is pursuing Rett approval, first, for the stated reasons... but there's no doubt in my mind that AD approval will be close on the heels.
1. Rett approval doesn't have the "political challenges" as AD.
2. Rett approval offers a PR voucher.
3. Rett can be addressed without large partnerships... quicker to commercialization.
4. AD approval for an already approved drug will be much easier/quicker, in the face of political "headwinds".
It'll be most interesting to see the partnerships Anavex selects for worldwide AD commercialization, next year.
Regardless of how excellent the Excellence data are, you can bet that the usual perpetrators will try to twist it into some lie about "cherry picking" or "changed endpoints" or "insufficient n" or "flawed data" or "fumbled TLR" .
It's what cabal soldiers are paid to do.
Sadly their fines and jail time are nothing for the crime they committed causing $10M+ in losses for investors. That's the problem.
I believe you're right, since the OLE started in Oct 2019. Many have completed their 96 weeks.
...and having a 48-wk readout this year will certainly help the cause (if Investor's statement holds true).
Well, this might put a hole in the FUD narrative... to perhaps have a "peek" this year.
With LPLV for 96 weeks at July 31, 2024, then the "readout ... done at 48 weeks" should be done soon.
With the ATTENTION AD OLE trial scheduled to end next July, it will fit well as a confirmatory trial for AA
or traditional approval, about the same time.
When I occasionally scan the board and see this much FUD noise, it tells me that good things are about to happen.
Why else would they spend so much time and energy here? Ans: because they're paid.
The collusive cabal's job is to instill max pain to maximize their illicit trading profits and to flush out retail before news.
One would think that actual would be within 10% of estimated (i.e. 400)... but 350+ is good.
I'm pretty sure it's a remuneration thing that twists their postings FUDish.
Thanks for the link! 450 est. patients...
STUDY START (ACTUAL)
2019-10-10
PRIMARY COMPLETION (ESTIMATED)
2024-07-31
STUDY COMPLETION (ESTIMATED)
2024-07-31
ENROLLMENT (ESTIMATED)
450
STUDY TYPE
Interventional
If AF is involved, it's definite organized collusion with his associate HFs (Citadel, etc.)... the cabal.
He doesn't spin fake narratives for free.
Okay FUDster! See ya!
BTW, where'd your biochecker buddy run off to?
It'll happen as we get to approvals next year. That'll be when the collusive AF Cabal is called off and many here will disappear.
Let's hope we are fortunate enough to see the institutional ownership work its way up to 68% at a time
Yep... another confirmed cabal soldier. They're overrunning this board with ad nauseum FUD.
With that denial of the obvious, we certainly know to which camp you belong. Noted.
Rikker is a boot-licking FUDbot.
LOL... a typical FUDster tactic.
You clearly don't understand the extent of collusive manipulation... or perhaps you do and are just purposely downplaying it.
I've seen dozens of positive announcements (some P3 results), from particular biotechs, that get met with pre-written hit pieces (usually from AF). These are planned and coordinated by collusive HFs, who pay AF, as well as our resident FUDsters for their FUD services.
Wake up and smell the coffee!
This is obviously baseless FUD...
Obviously the P2b/3 just isn't good enough for that. Meanwhile Anavex is still sitting around one quarter later considering having a chat with the FDA about a maybe pathway for Accelerated Approval.
LOL. Did you miss AF's lying hit piece he released when the SP was at its recent ascending apex, which began the coordinated selloff and shorting?
That wasn't a random event; it was tied to collusive manipulation. I do think you know this... everyone does!