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Falconer has soluble AB 42 been a factor in PD?
So Biogen beat placebo by 27% at 18 months in slowing decline..
Simple math is all I can do..
Early ad at 18 months placebo group probably a
5 point drop in AD cog score.. think scale is 70..
So 27% less drop after 18 months is..
A 3.5 drop in AD cog score?
Or other >20 point scale..MME
Placebo group in early ad drops 3 points at 18 months..20 to 17
So Biogen drops 2 points?
20 to 18?
Hey it’s better than SOC but that is like saying you got the Jab from covid.. it doesn’t mean shxt.
Think cassava and anavex and even biovie
Will blow this away..
Good find
Sorry
$20,000.000.000 would be around
$200 PPS
The third time should have been considered criminal by the company and institutional investors
We begged them to not do it..
I was on message boards..
But BP sometimes is as criminal as BG
$20,000,000 would be around $200 ps
Mining companies are valued not just by what they sell..
They are valued by the amount of the asset they own..
So regardless of when approval by fda..occurs..
Humanity will know value of asset..
The asset will be valued..
Biogen went for three runs
each over $20,000,000,000 in valuation increase on the pump of their failed brain sweller..
Biogen did make a lot of people money so they fell off the cliff with the devil they knew..
Good riddance..
We are not the devil.. so we shall see
Once the asset is proved it must be valued.
Like gold assays..
It ain’t out of the mountain yet..
but we know it’s there
I expect that we will either repeat the many ups and downs of our great companies share price or we will repeat the great ups and downs of our great Conakry’s share price..
Started at $.20. Reverse 4 for 1
Start at $.80…now at $12!
How many stocks have gone down since we have gone up? A lot..
Now we reach out for the brass bring..
Avxl will go up
Avxl will go down
So far .. overall has been up..
Look for the general trend to continue
Really we can’t wait one effing day? Cut it out
Noob you are not ignored yet..
Enjoy
What if ..proper sigma 1 agonization
Allows proliferation of sigma 1 throughout body.. including impregnating cells that didn’t use to have this mechanism through
mRNA or exosomes? Or through new tcells ? The body can smell a winner just like it can fight a loser
Well they are not going to be titrated up past what they can handle..
But if they tell you high dosage is the key
to staying alive.. what do you think you can handle?
The whole Raj is Everdeen psycho stuff works like magic!
Everyone please wait until tomorrow..
My account funds today and you guys are costing me thousands.. slow down..
Think about it..
You got plenty of time.. DrM is so slow
Just threw $500 on the roulette wheel..
Come on 15
Yes
Here is an interesting query..
Does our formaula lack psychological
effect because ….
The content of psychoactive chemical is so low.. or because we have formulated psychoactive ingredient out?
Meaning we may dose more of our formulate and still not receive psychoactive effect.. or
Is it that we must limit our dosage or
Have paychological effect?
Interesting..
Shhhh..
Still trying to buy more..
Don’t tell anyone that the human
body is stronger and more able to respond
to S1r agonization in early AD..
Wanna talk about the Heaven Storm that is about to hit the World?
Wait a couple of days please
I. Don’t think that is
A given.. however the phase 1. Trials uskualy are ncot blinded so this is a
Very good sign.
After reading Yale announce it does seem
Algernon has done what they may to protect IP ..
This. Probably savers them a lot of ‘money..
I again direct the company to fill how anavex lead in funding clinical research
What is
Unfortunate is we Are now competing with
Them For intellectual
Property on everything ..
The rumor is these mushrooms may encourage brain cell growth..
How ,will that be separated from depression
?
What thaw heck does that mean?
It will pr and be up way before CTAD
But now that I think about it..
Everyone on this board knows more about Blarcamesine efficacy than DrM..
So whatever everyone here says is probably right..
Great..
Except
DrM said key factor is High Dosage..
Rinse spit repeat
6 years ago would make her 83..
Now for those of you who are young and say what does that matter?
3 years could be .. a wedding, a birth
a memory shared.. time spent with grandchildren ..who knows! Life matters at 80 just as much as life matters in the womb..
Look
This WAS the plan..
80% go rate at 50 Mg
BUT the Plan has changed
The new PLAN..
50 Mg given early enough in Dementia disease is the common denominator ..
Not wild type not combination..
50mg early enough in disease..
Prophylaxis..get it..
Don’t buy anymore yet .. I will tell you after I buy some more than you can buy some more
Valerie was 77 then.. would have passed away from ad by 80..
appears she’s.still alive as no obituary anywhere to be found..
Didn’t see any new paintings..
But. Anything she painted after being saved by Blarcamesine should be in a museum
I liked Sava
Data.
Just don’t understand bio mechanism .
Plus thinking
With Blarcamesine dementia going to soon be disease of the past
Also DrM.. has already told us
The common denominator for this trial and Blarcamesine is high dosage..
What do you think that commonality is for high dosage?
Let it sink in
I hope I wrong because I am trying to buy more
I hope I am wrong
But late Friday run looked like capitulation
From the shorts..
Normally a fri afternoon option expire rolls down to lower strike..5
The. rolls down a little more monday..
Monday midday picks up for fear of teus pr..
The upswing fri felt odd
I have no doubt .. zero
Agreed Ba.. ridiculous to have placebo arm when so many failed trials with ample placebo documentation have already occurred
It is early Alzheimers
The progression of the disease varies greatly at the early stage.
It is very possible that some patients will not have deteriorated after 48 months..
In the placebo arm whatever that number is.. simply deduct that number from the
responders in the 30mg cohort and the 50mg cohort..
So if 5 out of 170 placebo consort are. Close to baseline..
And 85 from the 30 Mg cohort are at baseline or above.. reduce that number to 80..
And when 170 of theb50 Mg are at baseline of above you reduce that to 165..
Making the number 245 out of 330 are at or above baseline due to Blarcamesine..
Why argue minutiae? The meat of the data will leave zero doubt only adulation and joy and
will make these arguments pointless for the shorts.
We will blow this away
Blow. It. Away
Normally 4 point drop over year for placebo.. but it is early Alzheimers..
outliers in placebo should have been removed.. I don’t think it’s impossible
that a couple of early Ad patients have fone better( there can be a placebo effect)
The placebo effect is real especially for early ad..
What is about to get even realer..
Is called the Blarcamesine EFFECT!
When Blarcamesine so agonizes the human chaperone Sigma One Receptor
that the Sigma One Expression throughout
the human body explodes!!!!!
The Blarcamesine Effect will be revealed
Soon
Nothing ever like it ever.. in the history of human medicine.. strap yourselves in..
Put in your oxygen masks.. the air is about to get thin..
Mine is at baseline or above
Anavex May delay tlr now to confirm and prepare for scrutiny.. that is it.
They have TLD.. it’s been analyzed and shared.. they have a short window to confirm and prepare the pr.. they might be able to argue to wait until 8k. ..
but no more really…
Dr mcfarlane will still get to be hero..
All eyes will be upon him..