I might be crazy but I did buy back some shares today based on our trading at below book value. I figure I have enough losses still to carry over a lifetime- regardless of the wash rule.

Oh yeah - and I almost break even on my 2 year investment - with the shares I held onto

Swg_trader - did you read the post by an internist on this board / gpuppy? - "Any responsible oncologist is not going to allow his/her patient to die without a fight for the sake of a trial. Hence, they were terminated from the trial. If this decision was made for all patients who were doing poorly in the control arm, it is understandable to see why the control arm survival was much greater than historical data."

Thank you peregr and ebo. I have enough shares still in that if they get bought out - there is a chance I could come close to break even. I am wondering at the share price drop and the wall around.40 - is it possible that the company took the money out of the market for a set number of days to buy shareholders shares at book value? Is there some rule that a company must be able to buy their shares back at book value in cases of terrible news? I apologize in advance if this is a stupid question. I'm just trying to understand how the market cap dropped in the blink of an eye and the current share price wall.

Good point. If I sold on 2-26 and the settlement date is 3-2, would I need to wait till 4-1 to buy any shares back in order to claim the tax loss? Also, if I recall correctly - you can only claim a certain amount as a loss and then you need to spread the loss over a few years? It's been a long time since I took a huge stock loss.

Thank you north - your words are much appreciated at the moment I would probably sneak in to buy a few shares back, if I saw management buying shares at these levels, but I believe someone here stated - that is as likely as spotting Bigfoot at a barbecue picnic. Luddite - excellent description - lol I can think of a few other words too warm regards!

Thank you gpuppy- this is what I thought might have happened. This will have an effect on many current cancer trials across the board - won't it? BTW- My husband is an internist as well, but he has no interest in stock investments - well until this fiasco. Now he doesn't want me to look at a stock message board ever again and hand all money over to our investment advisor. Obviously I listen well - cause here I am reading/posting -

What I'm unclear on is - where does this current predicament leave the company's short term financial situation? Can they recover from this situation without further shareholder destruction in the near term? This is why I'm 80% out on a huge loss. I believe in the science based on scientific publications and can see a demand in immunotherapy combo trials, but I'm unclear as to what this set-back will do to the company financially? Any thoughts? Wait a month, take the tax loss, let the dust settle?

I personally want to see management buy shares open market - this would be my queue to possibly buy back some of the shares I sold at a huge loss. Until then- I'm 80% out now - depressing that I lost so much money.

James there was a discussion that patients not responding to therapy in either arm could go on to be treated with other therapies such as opdivo and keytuda, which may be another explanation for why the control arm performed so well. If that is the case, this could cause disruption in cancer trials across the board.

Yes - that was my ultimate opinion as well - trial assumptions failed. There is nothing else we can assume at this point. There was an interesting discussion that patients not responding were going on for further treatment with drugs such as keytuda and opdivo in both arms, which might be why the control arm dramatically improved mos.

Thank you JQ- so my understanding is that most likely Bavi performs similarly to keytuda and opdivo- hence no big delta between the control arm and Bavi. So now the best place for Bavi is in combo with these other drugs. In the interim it will be a battle between combo immunotherapy and car-t. We now await to see if a BP wants Bavi as part of their cocktail. Does that about sum it up?

JQ - you seem to be knowledgeable - how does the dmc/ FDA take into account a study if opdivo is added to patients in the control arm? Ex stated "But why do you assume it was the chemo, and not Opdivo, that led to expectedly long OS in the SUNRISE control arm?

Opdivo use will be very high in SUNRISE.

. Once a patient progresses it would be the clear choice for those who are still fighting."

My opinion/ wild guesses, bavi beat doce by maybe a month producing a mos somewhere around 11 vs 12. Opdivo was approved with 9 vs 12. Maybe immuno in silo can only do so much. The future will be immuno combos and CAR-T. Unfortunately, pphm no longer has the option of selling bavi in 2017. So we have no way of funding more trials except a buyout or cash partner. I based my investment thesis on PPHM being able to sell bavi in 2017. Now, I have to base my investment thesis on the likely hood of them getting a cash partner or a buyout. Since I'm not an insider, I have no idea what the odds are of either. But my guess is that car-t will eventually beat out silo immuno, so a buyout might make sense to a BP invested in immuno.

I sold out 80% of my position because my original investment thesis was broken. I held onto 20% because of the possibility of a buyout. Maybe I will get lucky and break even?

I feel that way too MH. I genuinely believed that we were having great results and that there was a plan to move PPHM into the big pharmaceutical world. Such a shame it went the other direction. I looked at the asco chart on the phase 2 results and believed that the ecog0 patients benefitted hugely. Since the bavi arm in phase 3 would be 50% ecog0 I thought bavi would have shown a mos of 14-15 months and doc would have a 10-11 month mos. I guess both arms had about a 11-12 month mos? I hope they go through the blood work and test for bavi to ensure the DMC was unblinded properly.

I kept 1/4 my position- if they get bought out - there's a chance I break even. Otherwise, I lost my salary this year on PPHM - depressing.

Haven't they been taking blood samples that can tell which patients actually had bavi? Does anyone know if they had access to this info yet? Does the dmc use the blood tests to ensure that the arms are unblinded correctly when making their recommendations?

Please let there be a plan b - I hope you're correct.

so sad. I still have my shares - it doesn't make sense to me to sell at this level. Wow- a whole year's salary gone in the blink of an eye. I can't even drink because I have responsibilities I have to attend - uggh

Wasn't the short report as of 2-12 when the stock was at .88? Now the stock has rebounded .15 - so perhaps good news is coming? There are now 101 toots, 18 new, 53 increased - I believe.

Just noticed PPHM currently has 101 institutional holders - coincidence?? Looking at the Nasdaq site.

Awesome! Please let there be good PPHM news tomorrow!

Interesting- does that mean if news breaks tomorrow, then no one can short sell because of this "short sale breaker" triggered today?

Krak - big smile - nice post yesterday

I have been reading posts though-out the day, with a heavy heart. Although I don't physically know any one on this board, it does feel like an extended family at times and this news does make me sad. Same as when I read krak's post. So, I'm, wishing all the posters/ readers here the best in life whatever it may be. Quality time with family and people, that energize us, trumps material things any day.

... Now, will we see one 101 volume trade premarket in keeping with a possible countdown tomorrow? Are we almost there, yet?

"Good Luck, although something tells me CFH is going to be more interested in all this ICT stuff then you" - reading everything while waiting for my hot stone massage this morning wishing I had more time in my day for these types of fun projects!

One new position added since 2-17 before there were 17 now there are 18. Was Goldman Sachs there in the 17 from 2 days ago or is this the new one?

Lol - so many times I have read posts here and laughed, but have refrained from posting cause it's off topic, but you guys crack me up. Nice to see positive humorous posts

CP- cheynew reported the 101 sequence every day this week and Biopharm brought up the black rock shares ending in 101. Below cheynew =CN
2/15 no trading
2-16 CN@802 pre market reports 202 shares
2-17 CN@718 pre market reports 101 shares traded pre market. It means nothing.
2-17 CN @1708 report 3 trades all at 1.03 for a volume of 101
2-18 CN pre market reports 1.15 trade volume 101
2-18 CN after market reports 1 traded at 1.04 volume 101
2-19 CN this morn reports first trade at 1.05 volume 101 followed by trade 3 hours later at 1.03 volume 101

12353101 - Biopharm mentioned the last three numbers are 101 which caught my eye.

There is a pattern - far fetched or not.

Cheers to the weekend!

Hey, a girl can dream big too Honestly, I am not one of those people that believe in superstition or try to correlate random events or numbers to future events. I do see random coincidences and find humor However, in this situation, someone has deliberately bought shares in a pattern and that pattern does coincidental have a match to the black rock shares. So either someone jests with us or not. My degree is in computer science not the arts

Thank you cheynew for keeping track of these interesting 101 activities.
08:52:13 t 1.03 101 NDD
08:01:27 t 1.00 161 EDGX
06:03:32 t 1.05 101 ARCA

Coincidentally - the black rock shares were 12,353,101

There are only 4 trading day this week . 1 2 3 5 ... 3 Today is day 5 on a week with four trading days ... followed by three. And we have two different 101 entries almost 3 hours apart - one at 1.05 followed by 1.03 - Hmmm??? It really makes me wonder if someone out there is doing a count down to some event.

And it was timed for 4:04 lol - clever now we will have to wait till tomorrow morning to see if we get 4 101 trades - the suspense is killing me

Was there a 101 at 1.04 trade after hours today? Will we see 4 101 shares traded pre market tomorrow and is this a count to 10 code or something like that? Lol

Hopefilled- My understanding is car-t is mainly being used for incurable blood cancer. I hope they figure out how to make this safer and use on solid tumors with similar results, but it looks like this may be many years away from being marketable, just from reading juno's pipeline and reading this article. Bavi is closer to being marketable and has a solid safety rating - just my opinion - keeping my money on PPHM.

Btw- I hope the 1.15 101 is a signal that bavi first look in occurred and is beating 15 to 10 MOS

52 increased positions and 17 new positions. Interesting, on the new tab, advocacy wealth management has one shared held? Does this mean that company invested only $1??

Chevalblanc - that makes a lot of sense. I'm going to rethink this simulation based on that logical assumption that the control arm had 17% of patients alive at 15 months because it include a mix of bavi 1 mg patients. Also, I think the high dropouts were probably Ecog 2 patients, which bavi had 25% of this patient group, so I will figure out if I can factor that in as well. Without coffee, it appears that perhaps cp and ex may be more correct with 100% 420 days applied to the control arm, which may mean that bavi is doing better than 15 MOS. in any case, they only need 2 month improvement and that appears to be golden at this point.

CP, I just want to clarify, did you use 420 days from the simulated enrollment date as the event date for the control arm? 420/30.4 = 13.8 months. According to the link below, it appears that almost 17% of the control arm for phase 2 was still alive at 15 months. I attempted to account for that with percentages on the distribution buckets. Perhaps this is why my event simulation is lower than yours? I also simulated 24 dropouts, which lowered the number of events.

http://www.peregrineinc.com/images/stories/pdfs/2013_asco_nsclc.pdf

CP, thanks. First, just want to remind everyone this is all speculation. Basically, If we assume that N=582 and first look-in occurs at .8*.33*582 ( which is approximately 154) and we hinder the simulation at 3*the n=8 dropout – I believe JQ mentioned ( so we have 24 dropouts) and we further hinder the simulation by giving the control arm a MOS of 10 versus 9.4 in other trials mentioned. Then, if we use CP’s enrollment data and use a MOS of 15 for the Bavi arm vs MOS of 10 for the control arm – we may have already triggered a first look-in. So either we are doing around 15 MOS or better or look-in has occurred and data is being evaluated. When I ran this simulation as of today we would have 164 events even with the 24 dropouts. I really did this randomly using modulus on the primary key – so the buckets aren’t perfect or completely realistic although they do produce the 10 vs 15 MOS.
BAVI events as of today in this simulation would be 55 ( took out the dropouts) vs the control arm of 109 events. I am also questioning if enrollment was really this slow – only 27 enrolled in the first half of 2014. This makes a big difference on the simulation, if enrollment was not this slow – then I might think that they already had first look-in and are reviewing data – assuming they need 154 events to trigger first look-in.

If we haven't had first look-in and we had the slow enrollment start-up shown in CP's spreadsheet
even with 24 dropouts, we may be exceeding 10 vs 15 MOS. See below logic followed by the data ouput
of a sample simulation - which of course is truly meaningless without real info - just speculation and I'm not sure if the data dump will show up properly from my iPhone.
I can change variables and assumptions if anyone wants me to:

/************* THIS IS THE BACKGROUND DATA DEVELOPMENT SECTION ********/

/*** HOW THIS DATA WAS CREATED ***/
drop table cp_enroll_simulation;
create table cp_enroll_simulation
( table_seq number,
enrol_total number,
enrol_char varchar2(30),
num1 number,
num2 number,
num3 number,
num4 number
) tablespace users;

-- used sqlldr to import CP's spreadsheet, unsure what num1 - num4 are and I want to run my own simulation.

alter table cp_enroll_simulation add enrol_date date;

update cp_enroll_simulation set enrol_date = to_date(enrol_char,'YYYY-MM-DD');

commit;

create sequence cp_key;


create table cp_enroll_simulation_improved
as
select cp_key.nextval as cp_key, cp.*
from
(select cp.* from cp_enroll_simulation cp order by cp.enrol_date) cp ;

select * from cp_enroll_simulation_improved order by enrol_date;


alter table cp_enroll_simulation_improved add (num_patients_enrol_on_this_dt number);

update cp_enroll_simulation_improved cp1 set cp1.num_patients_enrol_on_this_dt
= ( select CP1.ENROL_TOTAL - cp2.enrol_total from cp_enroll_simulation_improved cp2 where cp2.cp_key = CP1.cp_key - 1) ;
commit;

update cp_enroll_simulation_improved set num_patients_enrol_on_this_dt = 0 where cp_key = 1;
commit;

-- 582 total patients enrolled
select sum(enrol_total), sum(num1), sum(num2), sum(num3), sum(num4) , sum(num_patients_enrol_on_this_dt)
from cp_enroll_simulation_improved order by enrol_date;

-- this shows only 4 records where > 1 people were enrolled on the same day - each had 2 enrollees
select enrol_date, num_patients_enrol_on_this_dt
from cp_enroll_simulation_improved
where num_patients_enrol_on_this_dt > 1
order by enrol_date;

select * from cp_enroll_simulation_improved;

-- now can create a realistic simulation whoop whoop!
------------
drop sequence cp_key;
create sequence cp_key;
drop table full_simulation;
create table full_simulation
as
select cp_key.nextval as ptnt_seq,
enrol_date
from cp_enroll_simulation_improved where num_patients_enrol_on_this_dt =1;

-- the 4 enrollment dates that have 2 patients enrolled, manually isnert
begin
insert into full_simulation (ptnt_seq, enrol_date) values (cp_key.nextval, to_date('07/21/2015','MM/DD/YYYY'));
insert into full_simulation (ptnt_seq, enrol_date) values (cp_key.nextval, to_date('07/21/2015','MM/DD/YYYY'));
insert into full_simulation (ptnt_seq, enrol_date) values (cp_key.nextval, to_date('09/23/2015','MM/DD/YYYY'));
insert into full_simulation (ptnt_seq, enrol_date) values (cp_key.nextval, to_date('09/23/2015','MM/DD/YYYY'));
insert into full_simulation (ptnt_seq, enrol_date) values (cp_key.nextval, to_date('11/27/2015','MM/DD/YYYY'));
insert into full_simulation (ptnt_seq, enrol_date) values (cp_key.nextval, to_date('11/27/2015','MM/DD/YYYY'));
insert into full_simulation (ptnt_seq, enrol_date) values (cp_key.nextval, to_date('01/30/2016','MM/DD/YYYY'));
insert into full_simulation (ptnt_seq, enrol_date) values (cp_key.nextval, to_date('01/30/2016','MM/DD/YYYY'));
end;
commit;
-- 582 - data integrity preserved
select count(*), treatment_arm from full_simulation group by treatment_arm;
------------------ PATIENTS ENROLLED IN FULL_SIMULATION TABLE

-- now need to break up the group into 4 buckets, apply distribution and add dropouts

alter table full_simulation add treatment_arm varchar2(20);

-- make half bavi and half control and divide into 2 seperate ecog
-- this means you must use modulus 4 to create two equal buckets which will
-- make 1/4 of the buckets 0, 1/4 of the buckets 1, ... to 3
begin
update full_simulation set treatment_arm = 'BAVI ECOG0'
where mod(ptnt_seq,4) = 0;
update full_simulation set treatment_arm = 'BAVI ECOG1'
where mod(ptnt_seq,4) = 1;
update full_simulation set treatment_arm = 'CONTROL ECOG0'
where mod(ptnt_seq,4) = 2;
update full_simulation set treatment_arm = 'CONTROL ECOG1'
where mod(ptnt_seq,4) = 3;
commit;
end;
-- MOS BAVI ECOG0 17.12
-- MOS BAVI ECOG1 12
-- MOS CONTROL ECOG0 10.7
-- MOS CONTROL ECOG1 8

select (event_date - enrol_date) /30.4, f.* , mod(ptnt_seq, 100) from full_simulation f where treatment_arm = 'BAVI ECOG0' order by (event_date - enrol_date) /30.4;

-- what I'm striving for here is ultimately a 10 vs 15 month simulation

alter table full_simulation add mos number (9,2);
begin
update full_simulation set mos = 17 WHERE treatment_arm = 'BAVI ECOG0'; -- 145
update full_simulation set mos = 12 WHERE treatment_arm = 'BAVI ECOG1'; -- 146
update full_simulation set mos = 10 WHERE treatment_arm = 'CONTROL ECOG0'; -- 146
update full_simulation set mos = 8 where treatment_arm = 'CONTROL ECOG1'; -- 145
commit;
end;

-- apply approximate distribution will be slightly different for bavi
38% will event by mos -2 months =221
12% will event by MOS =69
7% will event by mos + 3 months =41
25% will event by mos + 8 months = 145
12% will event by mos + 13 months = 70
6% will event by mos + 15 months = 35



alter table full_simulation add distribution_bucket varchar2(50);
-- applying the same distribution globally although this should be changed for bavi patients



begin

update full_simulation set distribution_bucket = 'MOS - 2 MONTHS'
where mod(ptnt_seq, 100) between 0 and 37 and treatment_arm = 'CONTROL ECOG0';
update full_simulation set distribution_bucket = 'MOS'
where mod (ptnt_seq,100) between 38 and 52 and treatment_arm = 'CONTROL ECOG0';
update full_simulation set distribution_bucket = 'MOS + 3 MONTHS'
where mod(ptnt_seq,100) between 53 and 59 and treatment_arm = 'CONTROL ECOG0';
update full_simulation set distribution_bucket = 'MOS + 8 MONTHS'
where mod(ptnt_seq,100) between 60 and 82 and treatment_arm = 'CONTROL ECOG0';
update full_simulation set distribution_bucket = 'MOS + 13 MONTHS'
where mod(ptnt_seq,100) between 83 and 94 and treatment_arm = 'CONTROL ECOG0';
update full_simulation set distribution_bucket = 'MOS + 15 MONTHS'
where mod(ptnt_seq,100) between 95 and 99 and treatment_arm = 'CONTROL ECOG0';

update full_simulation set distribution_bucket = 'MOS - 2 MONTHS'
where mod(ptnt_seq, 100) between 0 and 37 and treatment_arm = 'CONTROL ECOG1';
update full_simulation set distribution_bucket = 'MOS'
where mod (ptnt_seq,100) between 38 and 53 and treatment_arm = 'CONTROL ECOG1';
update full_simulation set distribution_bucket = 'MOS + 3 MONTHS'
where mod(ptnt_seq,100) between 54 and 60 and treatment_arm = 'CONTROL ECOG1';
update full_simulation set distribution_bucket = 'MOS + 8 MONTHS'
where mod(ptnt_seq,100) between 61 and 82 and treatment_arm = 'CONTROL ECOG1';
update full_simulation set distribution_bucket = 'MOS + 13 MONTHS'
where mod(ptnt_seq,100) between 83 and 94 and treatment_arm = 'CONTROL ECOG1';
update full_simulation set distribution_bucket = 'MOS + 15 MONTHS'
where mod(ptnt_seq,100) between 95 and 99 and treatment_arm = 'CONTROL ECOG1';

update full_simulation set distribution_bucket = 'MOS - 2 MONTHS'
where mod(ptnt_seq, 100) between 0 and 37 and treatment_arm = 'BAVI ECOG0';
update full_simulation set distribution_bucket = 'MOS'
where mod (ptnt_seq,100) between 38 and 50 and treatment_arm = 'BAVI ECOG0';
update full_simulation set distribution_bucket = 'MOS + 3 MONTHS'
where mod(ptnt_seq,100) between 51 and 58 and treatment_arm = 'BAVI ECOG0';
update full_simulation set distribution_bucket = 'MOS + 8 MONTHS'
where mod(ptnt_seq,100) between 59 and 82 and treatment_arm = 'BAVI ECOG0';
update full_simulation set distribution_bucket = 'MOS + 13 MONTHS'
where mod(ptnt_seq,100) between 83 and 94 and treatment_arm = 'BAVI ECOG0';
update full_simulation set distribution_bucket = 'MOS + 15 MONTHS'
where mod(ptnt_seq,100) between 95 and 99 and treatment_arm = 'BAVI ECOG0';

update full_simulation set distribution_bucket = 'MOS - 2 MONTHS'
where mod(ptnt_seq, 100) between 0 and 37 and treatment_arm = 'BAVI ECOG1';
update full_simulation set distribution_bucket = 'MOS'
where mod (ptnt_seq,100) between 38 and 50 and treatment_arm = 'BAVI ECOG1';
update full_simulation set distribution_bucket = 'MOS + 3 MONTHS'
where mod(ptnt_seq,100) between 51 and 58 and treatment_arm = 'BAVI ECOG1';
update full_simulation set distribution_bucket = 'MOS + 8 MONTHS'
where mod(ptnt_seq,100) between 59 and 82 and treatment_arm = 'BAVI ECOG1';
update full_simulation set distribution_bucket = 'MOS + 13 MONTHS'
where mod(ptnt_seq,100) between 83 and 94 and treatment_arm = 'BAVI ECOG1';
update full_simulation set distribution_bucket = 'MOS + 15 MONTHS'
where mod(ptnt_seq,100) between 95 and 99 and treatment_arm = 'BAVI ECOG1';

commit;

end;


alter table full_simulation add median_end_date date;

begin
update full_simulation set median_end_date = (30.437 * mos) + enrol_date;
commit;
end;
alter table full_simulation add event_date date;

begin
update full_simulation set event_date = median_end_date - (2 *30.437)
where distribution_bucket = 'MOS - 2 MONTHS';

update full_simulation set event_date = median_end_date
where distribution_bucket = 'MOS';

update full_simulation set event_date = median_end_date + (3 *30.437)
where distribution_bucket = 'MOS + 3 MONTHS';

update full_simulation set event_date = median_end_date + (8 *30.437)
where distribution_bucket = 'MOS + 8 MONTHS';

update full_simulation set event_date = median_end_date + (13 *30.437)
where distribution_bucket = 'MOS + 13 MONTHS';



update full_simulation set event_date = median_end_date + (15 *30.437)
where distribution_bucket = 'MOS + 15 MONTHS';

commit;
end;
-- approximately 4% will drop out = 24

alter table full_simulation add dropout_flag varchar2(1) default 'N';

-- 24 drop out patients picked the first patient enrolled per distribution bucket and treatment arm as worst case scenario
update full_simulation f set f.dropout_flag = 'N';
commit;
update full_simulation f set f.dropout_flag = 'Y'
where ptnt_seq in ( select min(f2.ptnt_seq) from full_simulation f2
group by treatment_arm, distribution_bucket);
commit;


/***********************************************/
---------------end of logic to create simulation

/************* THIS IS THE QUERY SECTION, FOLLOWED BY A DATA DUMP ********/

select treatment_arm, count(*) from full_simulation group by treatment_arm;

-- TOTAL ENROLLED PER ARM
TREATMENT_ARM, COUNT(*)
'CONTROL ECOG1', 145
'BAVI ECOG0', 145
'CONTROL ECOG0', 146
'BAVI ECOG1', 146

select treatment_arm, distribution_bucket, count(*) from full_simulation group by treatment_arm, distribution_bucket order by distribution_bucket;

Buckets are not quite evenly distributed but ok, can attempt to change the buckets later
TREATMENT_ARM,DISTRIBUTION_BUCKET,COUNT(*)
'BAVI ECOG0','MOS', 18
'BAVI ECOG1','MOS', 18
'CONTROL ECOG0','MOS', 24
'CONTROL ECOG1','MOS', 24
'BAVI ECOG0','MOS + 13 MONTHS', 15
'BAVI ECOG1','MOS + 13 MONTHS', 15
'CONTROL ECOG0','MOS + 13 MONTHS',15
'CONTROL ECOG1','MOS + 13 MONTHS',15
'BAVI ECOG0','MOS + 15 MONTHS', 5
'BAVI ECOG1','MOS + 15 MONTHS', 5
'CONTROL ECOG0','MOS + 15 MONTHS', 5
'CONTROL ECOG1','MOS + 15 MONTHS', 10
'BAVI ECOG0','MOS + 3 MONTHS', 12
'BAVI ECOG1','MOS + 3 MONTHS', 12
'CONTROL ECOG0','MOS + 3 MONTHS', 12
'CONTROL ECOG1','MOS + 3 MONTHS', 12
'BAVI ECOG0','MOS + 8 MONTHS', 36
'BAVI ECOG1','MOS + 8 MONTHS', 36
'CONTROL ECOG0','MOS + 8 MONTHS', 36
'CONTROL ECOG1','MOS + 8 MONTHS', 30
'BAVI ECOG0','MOS - 2 MONTHS', 59
'BAVI ECOG1','MOS - 2 MONTHS', 60
'CONTROL ECOG0','MOS - 2 MONTHS', 54
'CONTROL ECOG1','MOS - 2 MONTHS', 54


select treatment_arm, count(*) from full_simulation where dropout_flag = 'Y' group by treatment_arm;

--DROP OUTS ARE EVENLY DISTRIBUTED
TREATMENT_ARM,COUNT(*)
'CONTROL ECOG1', 6
'BAVI ECOG0', 6
'CONTROL ECOG0', 6
'BAVI ECOG1', 6

select treatment_arm, count(*) from full_simulation where event_date <= sysdate and dropout_flag = 'N' group by treatment_arm;

-- EVENTS PER ARM minus the drop outs
TREATMENT_ARM,COUNT(*)
'CONTROL ECOG1', 60
'BAVI ECOG0', 20
'CONTROL ECOG0', 49
'BAVI ECOG1', 35

select count(*) from full_simulation where event_date <= sysdate and dropout_flag = 'N';
-- 164 events would have taken place as of today 2/16/2016, to trigger a first look-in we only need 154 events.


select treatment_arm, count(*), median(((event_date - enrol_date)/ 30.437)) MOS from full_simulation group by treatment_arm;


TREATMENT_ARM,COUNT(*), MOS
'BAVI ECOG0', 145, 17.0000001521053
'BAVI ECOG1', 146, 12.0000001521053
'CONTROL ECOG0',146, 10
'CONTROL ECOG1',145, 7.99999984789468

-- BAVI ARM is at 15 MOS
select median(((event_date - enrol_date)/ 30.437)) MOS from full_simulation where treatment_arm like 'BAVI%';
-- CONTROL is at 10 MOS
select median(((event_date - enrol_date)/ 30.437)) MOS from full_simulation where treatment_arm like 'CONTROL%';

PTNT_SEQ
ENROL_DATE
TREATMENT_ARM
MOS
DISTRIBUTION_BUCKET
MEDIAN_END_DATE
EVENT_DATE
DROPOUT_FLAG
13
6/1/2014
BAVI ECOG1
12
MOS - 2 MONTHS
6/1/2015 5:51:22 AM
4/1/2015 8:52:48 AM
N
14
6/3/2014
CONTROL ECOG0
10
MOS - 2 MONTHS
4/3/2015 8:52:48 AM
2/1/2015 11:54:14 AM
N
20
6/17/2014
BAVI ECOG0
17
MOS - 2 MONTHS
11/16/2015 10:17:46 AM
9/16/2015 1:19:12 PM
N
25
6/27/2014
BAVI ECOG1
12
MOS - 2 MONTHS
6/27/2015 5:51:22 AM
4/27/2015 8:52:48 AM
N
32
7/8/2014
BAVI ECOG0
17
MOS - 2 MONTHS
12/7/2015 10:17:46 AM
10/7/2015 1:19:12 PM
N
40
7/19/2014
BAVI ECOG0
17
MOS
12/18/2015 10:17:46 AM
12/18/2015 10:17:46 AM
Y
46
7/28/2014
CONTROL ECOG0
10
MOS
5/28/2015 8:52:48 AM
5/28/2015 8:52:48 AM
N
52
8/5/2014
BAVI ECOG0
17
MOS + 3 MONTHS
1/4/2016 10:17:46 AM
4/4/2016 5:45:36 PM
Y
58
8/12/2014
CONTROL ECOG0
10
MOS + 3 MONTHS
6/12/2015 8:52:48 AM
9/11/2015 4:20:38 PM
N
61
8/16/2014
BAVI ECOG1
12
MOS + 8 MONTHS
8/16/2015 5:51:22 AM
4/15/2016 5:45:36 PM
Y
72
8/30/2014
BAVI ECOG0
17
MOS + 8 MONTHS
1/29/2016 10:17:46 AM
9/28/2016 10:12:00 PM
N
77
9/4/2014
BAVI ECOG1
12
MOS + 8 MONTHS
9/4/2015 5:51:22 AM
5/4/2016 5:45:36 PM
N
83
9/11/2014
CONTROL ECOG1
8
MOS + 13 MONTHS
5/12/2015 11:54:14 AM
6/11/2016 4:14:52 AM
Y
89
9/18/2014
BAVI ECOG1
12
MOS + 13 MONTHS
9/18/2015 5:51:22 AM
10/17/2016 10:12:00 PM
N
106
10/8/2014
CONTROL ECOG0
10
MOS - 2 MONTHS
8/8/2015 8:52:48 AM
6/8/2015 11:54:14 AM
N
112
10/14/2014
BAVI ECOG0
17
MOS - 2 MONTHS
3/14/2016 10:17:46 AM
1/13/2016 1:19:12 PM
N
118
10/21/2014
CONTROL ECOG0
10
MOS - 2 MONTHS
8/21/2015 8:52:48 AM
6/21/2015 11:54:14 AM
N
127
10/30/2014
CONTROL ECOG1
8
MOS - 2 MONTHS
6/30/2015 11:54:14 AM
4/30/2015 2:55:40 PM
N
136
11/9/2014
BAVI ECOG0
17
MOS - 2 MONTHS
4/9/2016 10:17:46 AM
2/8/2016 1:19:12 PM
N
137
11/10/2014
BAVI ECOG1
12
MOS - 2 MONTHS
11/10/2015 5:51:22 AM
9/10/2015 8:52:48 AM
N
140
11/14/2014
BAVI ECOG0
17
MOS
4/14/2016 10:17:46 AM
4/14/2016 10:17:46 AM
N
145
11/19/2014
BAVI ECOG1
12
MOS
11/19/2015 5:51:22 AM
11/19/2015 5:51:22 AM
N
156
12/1/2014
BAVI ECOG0
17
MOS + 3 MONTHS
5/1/2016 10:17:46 AM
7/31/2016 5:45:36 PM
N
157
12/2/2014
BAVI ECOG1
12
MOS + 3 MONTHS
12/2/2015 5:51:22 AM
3/2/2016 1:19:12 PM
N
158
12/3/2014
CONTROL ECOG0
10
MOS + 3 MONTHS
10/3/2015 8:52:48 AM
1/2/2016 4:20:38 PM
N
168
12/13/2014
BAVI ECOG0
17
MOS + 8 MONTHS
5/13/2016 10:17:46 AM
1/11/2017 10:12:00 PM
N
179
12/25/2014
CONTROL ECOG1
8
MOS + 8 MONTHS
8/25/2015 11:54:14 AM
4/24/2016 11:48:28 PM
N
180
12/26/2014
BAVI ECOG0
17
MOS + 8 MONTHS
5/26/2016 10:17:46 AM
1/24/2017 10:12:00 PM
N
184
12/30/2014
BAVI ECOG0
17
MOS + 13 MONTHS
5/30/2016 10:17:46 AM
6/30/2017 2:38:24 AM
N
191
1/6/2015
CONTROL ECOG1
8
MOS + 13 MONTHS
9/6/2015 11:54:14 AM
10/6/2016 4:14:52 AM
N
207
1/23/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
9/23/2015 11:54:14 AM
7/24/2015 2:55:40 PM
N
212
1/28/2015
BAVI ECOG0
17
MOS - 2 MONTHS
6/28/2016 10:17:46 AM
4/28/2016 1:19:12 PM
N
213
1/29/2015
BAVI ECOG1
12
MOS - 2 MONTHS
1/29/2016 5:51:22 AM
11/29/2015 8:52:48 AM
N
219
2/4/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
10/5/2015 11:54:14 AM
8/5/2015 2:55:40 PM
N
232
2/18/2015
BAVI ECOG0
17
MOS - 2 MONTHS
7/19/2016 10:17:46 AM
5/19/2016 1:19:12 PM
N
237
2/23/2015
BAVI ECOG1
12
MOS - 2 MONTHS
2/23/2016 5:51:22 AM
12/24/2015 8:52:48 AM
N
240
2/26/2015
BAVI ECOG0
17
MOS
7/27/2016 10:17:46 AM
7/27/2016 10:17:46 AM
N
244
3/2/2015
BAVI ECOG0
17
MOS
7/31/2016 10:17:46 AM
7/31/2016 10:17:46 AM
N
249
3/7/2015
BAVI ECOG1
12
MOS
3/6/2016 5:51:22 AM
3/6/2016 5:51:22 AM
N
252
3/10/2015
BAVI ECOG0
17
MOS + 3 MONTHS
8/8/2016 10:17:46 AM
11/7/2016 5:45:36 PM
N
260
3/19/2015
BAVI ECOG0
17
MOS + 8 MONTHS
8/17/2016 10:17:46 AM
4/17/2017 10:12:00 PM
N
271
3/30/2015
CONTROL ECOG1
8
MOS + 8 MONTHS
11/28/2015 11:54:14 AM
7/28/2016 11:48:28 PM
N
281
4/9/2015
BAVI ECOG1
12
MOS + 8 MONTHS
4/8/2016 5:51:22 AM
12/7/2016 5:45:36 PM
N
287
4/15/2015
CONTROL ECOG1
8
MOS + 13 MONTHS
12/14/2015 11:54:14 AM
1/13/2017 4:14:52 AM
N
290
4/18/2015
CONTROL ECOG0
10
MOS + 13 MONTHS
2/16/2016 8:52:48 AM
3/18/2017 1:13:26 AM
N
296
4/24/2015
BAVI ECOG0
17
MOS + 15 MONTHS
9/22/2016 10:17:46 AM
12/22/2017 11:36:58 PM
N
304
5/2/2015
BAVI ECOG0
17
MOS - 2 MONTHS
9/30/2016 10:17:46 AM
7/31/2016 1:19:12 PM
N
311
5/9/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
1/7/2016 11:54:14 AM
11/7/2015 2:55:40 PM
N
318
5/16/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
3/15/2016 8:52:48 AM
1/14/2016 11:54:14 AM
N
330
5/28/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
3/27/2016 8:52:48 AM
1/26/2016 11:54:14 AM
N
339
6/6/2015
CONTROL ECOG1
8
MOS
2/4/2016 11:54:14 AM
2/4/2016 11:54:14 AM
N
358
6/25/2015
CONTROL ECOG0
10
MOS + 3 MONTHS
4/24/2016 8:52:48 AM
7/24/2016 4:20:38 PM
N
372
7/9/2015
BAVI ECOG0
17
MOS + 8 MONTHS
12/7/2016 10:17:46 AM
8/7/2017 10:12:00 PM
N
373
7/10/2015
BAVI ECOG1
12
MOS + 8 MONTHS
7/9/2016 5:51:22 AM
3/9/2017 5:45:36 PM
N
384
7/22/2015
BAVI ECOG0
17
MOS + 13 MONTHS
12/20/2016 10:17:46 AM
1/20/2018 2:38:24 AM
N
391
7/29/2015
CONTROL ECOG1
8
MOS + 13 MONTHS
3/28/2016 11:54:14 AM
4/28/2017 4:14:52 AM
N
397
8/4/2015
BAVI ECOG1
12
MOS + 15 MONTHS
8/3/2016 5:51:22 AM
11/2/2017 7:10:34 PM
N
408
8/15/2015
BAVI ECOG0
17
MOS - 2 MONTHS
1/13/2017 10:17:46 AM
11/13/2016 1:19:12 PM
N
409
8/16/2015
BAVI ECOG1
12
MOS - 2 MONTHS
8/15/2016 5:51:22 AM
6/15/2016 8:52:48 AM
N
419
8/26/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
4/25/2016 11:54:14 AM
2/24/2016 2:55:40 PM
N
420
8/27/2015
BAVI ECOG0
17
MOS - 2 MONTHS
1/25/2017 10:17:46 AM
11/25/2016 1:19:12 PM
N
428
9/4/2015
BAVI ECOG0
17
MOS - 2 MONTHS
2/2/2017 10:17:46 AM
12/3/2016 1:19:12 PM
N
432
9/8/2015
BAVI ECOG0
17
MOS - 2 MONTHS
2/6/2017 10:17:46 AM
12/7/2016 1:19:12 PM
N
433
9/9/2015
BAVI ECOG1
12
MOS - 2 MONTHS
9/8/2016 5:51:22 AM
7/9/2016 8:52:48 AM
N
434
9/10/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
7/10/2016 8:52:48 AM
5/10/2016 11:54:14 AM
N
435
9/11/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
5/11/2016 11:54:14 AM
3/11/2016 2:55:40 PM
N
436
9/12/2015
BAVI ECOG0
17
MOS - 2 MONTHS
2/10/2017 10:17:46 AM
12/11/2016 1:19:12 PM
N
437
9/13/2015
BAVI ECOG1
12
MOS - 2 MONTHS
9/12/2016 5:51:22 AM
7/13/2016 8:52:48 AM
N
438
9/14/2015
CONTROL ECOG0
10
MOS
7/14/2016 8:52:48 AM
7/14/2016 8:52:48 AM
N
441
9/17/2015
BAVI ECOG1
12
MOS
9/16/2016 5:51:22 AM
9/16/2016 5:51:22 AM
N
442
9/18/2015
CONTROL ECOG0
10
MOS
7/18/2016 8:52:48 AM
7/18/2016 8:52:48 AM
N
443
9/19/2015
CONTROL ECOG1
8
MOS
5/19/2016 11:54:14 AM
5/19/2016 11:54:14 AM
N
444
9/20/2015
BAVI ECOG0
17
MOS
2/18/2017 10:17:46 AM
2/18/2017 10:17:46 AM
N
446
9/22/2015
CONTROL ECOG0
10
MOS
7/22/2016 8:52:48 AM
7/22/2016 8:52:48 AM
N
447
9/24/2015
CONTROL ECOG1
8
MOS
5/24/2016 11:54:14 AM
5/24/2016 11:54:14 AM
N
448
9/25/2015
BAVI ECOG0
17
MOS
2/23/2017 10:17:46 AM
2/23/2017 10:17:46 AM
N
449
9/26/2015
BAVI ECOG1
12
MOS
9/25/2016 5:51:22 AM
9/25/2016 5:51:22 AM
N
450
9/27/2015
CONTROL ECOG0
10
MOS
7/27/2016 8:52:48 AM
7/27/2016 8:52:48 AM
N
452
9/29/2015
BAVI ECOG0
17
MOS + 3 MONTHS
2/27/2017 10:17:46 AM
5/29/2017 5:45:36 PM
N
453
9/30/2015
BAVI ECOG1
12
MOS + 3 MONTHS
9/29/2016 5:51:22 AM
12/29/2016 1:19:12 PM
N
454
10/1/2015
CONTROL ECOG0
10
MOS + 3 MONTHS
7/31/2016 8:52:48 AM
10/30/2016 4:20:38 PM
N
455
10/2/2015
CONTROL ECOG1
8
MOS + 3 MONTHS
6/1/2016 11:54:14 AM
8/31/2016 7:22:04 PM
N
456
10/3/2015
BAVI ECOG0
17
MOS + 3 MONTHS
3/3/2017 10:17:46 AM
6/2/2017 5:45:36 PM
N
457
10/4/2015
BAVI ECOG1
12
MOS + 3 MONTHS
10/3/2016 5:51:22 AM
1/2/2017 1:19:12 PM
N
459
10/6/2015
CONTROL ECOG1
8
MOS + 3 MONTHS
6/5/2016 11:54:14 AM
9/4/2016 7:22:04 PM
N
460
10/7/2015
BAVI ECOG0
17
MOS + 8 MONTHS
3/7/2017 10:17:46 AM
11/5/2017 10:12:00 PM
N
461
10/8/2015
BAVI ECOG1
12
MOS + 8 MONTHS
10/7/2016 5:51:22 AM
6/7/2017 5:45:36 PM
N
462
10/9/2015
CONTROL ECOG0
10
MOS + 8 MONTHS
8/8/2016 8:52:48 AM
4/8/2017 8:47:02 PM
N
463
10/10/2015
CONTROL ECOG1
8
MOS + 8 MONTHS
6/9/2016 11:54:14 AM
2/7/2017 11:48:28 PM
N
464
10/11/2015
BAVI ECOG0
17
MOS + 8 MONTHS
3/11/2017 10:17:46 AM
11/9/2017 10:12:00 PM
N
467
10/14/2015
CONTROL ECOG1
8
MOS + 8 MONTHS
6/13/2016 11:54:14 AM
2/11/2017 11:48:28 PM
N
468
10/15/2015
BAVI ECOG0
17
MOS + 8 MONTHS
3/15/2017 10:17:46 AM
11/13/2017 10:12:00 PM
N
469
10/16/2015
BAVI ECOG1
12
MOS + 8 MONTHS
10/15/2016 5:51:22 AM
6/15/2017 5:45:36 PM
N
470
10/17/2015
CONTROL ECOG0
10
MOS + 8 MONTHS
8/16/2016 8:52:48 AM
4/16/2017 8:47:02 PM
N
472
10/19/2015
BAVI ECOG0
17
MOS + 8 MONTHS
3/19/2017 10:17:46 AM
11/17/2017 10:12:00 PM
N
473
10/20/2015
BAVI ECOG1
12
MOS + 8 MONTHS
10/19/2016 5:51:22 AM
6/19/2017 5:45:36 PM
N
474
10/21/2015
CONTROL ECOG0
10
MOS + 8 MONTHS
8/20/2016 8:52:48 AM
4/20/2017 8:47:02 PM
N
475
10/22/2015
CONTROL ECOG1
8
MOS + 8 MONTHS
6/21/2016 11:54:14 AM
2/19/2017 11:48:28 PM
N
476
10/23/2015
BAVI ECOG0
17
MOS + 8 MONTHS
3/23/2017 10:17:46 AM
11/21/2017 10:12:00 PM
N
477
10/24/2015
BAVI ECOG1
12
MOS + 8 MONTHS
10/23/2016 5:51:22 AM
6/23/2017 5:45:36 PM
N
480
10/27/2015
BAVI ECOG0
17
MOS + 8 MONTHS
3/27/2017 10:17:46 AM
11/25/2017 10:12:00 PM
N
481
10/28/2015
BAVI ECOG1
12
MOS + 8 MONTHS
10/27/2016 5:51:22 AM
6/27/2017 5:45:36 PM
N
482
10/29/2015
CONTROL ECOG0
10
MOS + 8 MONTHS
8/28/2016 8:52:48 AM
4/28/2017 8:47:02 PM
N
483
10/30/2015
CONTROL ECOG1
8
MOS + 13 MONTHS
6/29/2016 11:54:14 AM
7/30/2017 4:14:52 AM
N
485
11/1/2015
BAVI ECOG1
12
MOS + 13 MONTHS
10/31/2016 5:51:22 AM
11/30/2017 10:12:00 PM
N
486
11/2/2015
CONTROL ECOG0
10
MOS + 13 MONTHS
9/1/2016 8:52:48 AM
10/2/2017 1:13:26 AM
N
487
11/3/2015
CONTROL ECOG1
8
MOS + 13 MONTHS
7/3/2016 11:54:14 AM
8/3/2017 4:14:52 AM
N
488
11/4/2015
BAVI ECOG0
17
MOS + 13 MONTHS
4/4/2017 10:17:46 AM
5/5/2018 2:38:24 AM
N
490
11/6/2015
CONTROL ECOG0
10
MOS + 13 MONTHS
9/5/2016 8:52:48 AM
10/6/2017 1:13:26 AM
N
491
11/7/2015
CONTROL ECOG1
8
MOS + 13 MONTHS
7/7/2016 11:54:14 AM
8/7/2017 4:14:52 AM
N
492
11/8/2015
BAVI ECOG0
17
MOS + 13 MONTHS
4/8/2017 10:17:46 AM
5/9/2018 2:38:24 AM
N
494
11/10/2015
CONTROL ECOG0
10
MOS + 13 MONTHS
9/9/2016 8:52:48 AM
10/10/2017 1:13:26 AM
N
496
11/12/2015
BAVI ECOG0
17
MOS + 15 MONTHS
4/12/2017 10:17:46 AM
7/12/2018 11:36:58 PM
N
497
11/13/2015
BAVI ECOG1
12
MOS + 15 MONTHS
11/12/2016 5:51:22 AM
2/11/2018 7:10:34 PM
N
498
11/14/2015
CONTROL ECOG0
10
MOS + 15 MONTHS
9/13/2016 8:52:48 AM
12/13/2017 10:12:00 PM
N
499
11/15/2015
CONTROL ECOG1
8
MOS + 15 MONTHS
7/15/2016 11:54:14 AM
10/15/2017 1:13:26 AM
N
502
11/18/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
9/17/2016 8:52:48 AM
7/18/2016 11:54:14 AM
N
503
11/19/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
7/19/2016 11:54:14 AM
5/19/2016 2:55:40 PM
N
505
11/21/2015
BAVI ECOG1
12
MOS - 2 MONTHS
11/20/2016 5:51:22 AM
9/20/2016 8:52:48 AM
N
507
11/23/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
7/23/2016 11:54:14 AM
5/23/2016 2:55:40 PM
N
508
11/24/2015
BAVI ECOG0
17
MOS - 2 MONTHS
4/24/2017 10:17:46 AM
2/22/2017 1:19:12 PM
N
510
11/26/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
9/25/2016 8:52:48 AM
7/26/2016 11:54:14 AM
N
511
11/28/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
7/28/2016 11:54:14 AM
5/28/2016 2:55:40 PM
N
513
11/30/2015
BAVI ECOG1
12
MOS - 2 MONTHS
11/29/2016 5:51:22 AM
9/29/2016 8:52:48 AM
N
514
12/1/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
9/30/2016 8:52:48 AM
7/31/2016 11:54:14 AM
N
515
12/2/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
8/1/2016 11:54:14 AM
6/1/2016 2:55:40 PM
N
518
12/5/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
10/4/2016 8:52:48 AM
8/4/2016 11:54:14 AM
N
519
12/6/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
8/5/2016 11:54:14 AM
6/5/2016 2:55:40 PM
N
520
12/7/2015
BAVI ECOG0
17
MOS - 2 MONTHS
5/7/2017 10:17:46 AM
3/7/2017 1:19:12 PM
N
521
12/8/2015
BAVI ECOG1
12
MOS - 2 MONTHS
12/7/2016 5:51:22 AM
10/7/2016 8:52:48 AM
N
522
12/9/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
10/8/2016 8:52:48 AM
8/8/2016 11:54:14 AM
N
524
12/11/2015
BAVI ECOG0
17
MOS - 2 MONTHS
5/11/2017 10:17:46 AM
3/11/2017 1:19:12 PM
N
526
12/13/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
10/12/2016 8:52:48 AM
8/12/2016 11:54:14 AM
N
527
12/14/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
8/13/2016 11:54:14 AM
6/13/2016 2:55:40 PM
N
529
12/16/2015
BAVI ECOG1
12
MOS - 2 MONTHS
12/15/2016 5:51:22 AM
10/15/2016 8:52:48 AM
N
530
12/17/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
10/16/2016 8:52:48 AM
8/16/2016 11:54:14 AM
N
531
12/18/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
8/17/2016 11:54:14 AM
6/17/2016 2:55:40 PM
N
533
12/20/2015
BAVI ECOG1
12
MOS - 2 MONTHS
12/19/2016 5:51:22 AM
10/19/2016 8:52:48 AM
N
535
12/22/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
8/21/2016 11:54:14 AM
6/21/2016 2:55:40 PM
N
536
12/23/2015
BAVI ECOG0
17
MOS - 2 MONTHS
5/23/2017 10:17:46 AM
3/23/2017 1:19:12 PM
N
537
12/24/2015
BAVI ECOG1
12
MOS - 2 MONTHS
12/23/2016 5:51:22 AM
10/23/2016 8:52:48 AM
N
539
12/26/2015
CONTROL ECOG1
8
MOS
8/25/2016 11:54:14 AM
8/25/2016 11:54:14 AM
N
540
12/27/2015
BAVI ECOG0
17
MOS
5/27/2017 10:17:46 AM
5/27/2017 10:17:46 AM
N
541
12/28/2015
BAVI ECOG1
12
MOS
12/27/2016 5:51:22 AM
12/27/2016 5:51:22 AM
N
542
12/29/2015
CONTROL ECOG0
10
MOS
10/28/2016 8:52:48 AM
10/28/2016 8:52:48 AM
N
546
1/2/2016
CONTROL ECOG0
10
MOS
11/1/2016 8:52:48 AM
11/1/2016 8:52:48 AM
N
547
1/3/2016
CONTROL ECOG1
8
MOS
9/2/2016 11:54:14 AM
9/2/2016 11:54:14 AM
N
549
1/5/2016
BAVI ECOG1
12
MOS
1/4/2017 5:51:22 AM
1/4/2017 5:51:22 AM
N
551
1/7/2016
CONTROL ECOG1
8
MOS
9/6/2016 11:54:14 AM
9/6/2016 11:54:14 AM
N
553
1/9/2016
BAVI ECOG1
12
MOS + 3 MONTHS
1/8/2017 5:51:22 AM
4/9/2017 1:19:12 PM
N
554
1/10/2016
CONTROL ECOG0
10
MOS + 3 MONTHS
11/9/2016 8:52:48 AM
2/8/2017 4:20:38 PM
N
555
1/11/2016
CONTROL ECOG1
8
MOS + 3 MONTHS
9/10/2016 11:54:14 AM
12/10/2016 7:22:04 PM
N
556
1/12/2016
BAVI ECOG0
17
MOS + 3 MONTHS
6/12/2017 10:17:46 AM
9/11/2017 5:45:36 PM
N
557
1/13/2016
BAVI ECOG1
12
MOS + 3 MONTHS
1/12/2017 5:51:22 AM
4/13/2017 1:19:12 PM
N
559
1/15/2016
CONTROL ECOG1
8
MOS + 3 MONTHS
9/14/2016 11:54:14 AM
12/14/2016 7:22:04 PM
N
560
1/16/2016
BAVI ECOG0
17
MOS + 8 MONTHS
6/16/2017 10:17:46 AM
2/14/2018 10:12:00 PM
N
561
1/17/2016
BAVI ECOG1
12
MOS + 8 MONTHS
1/16/2017 5:51:22 AM
9/16/2017 5:45:36 PM
N
563
1/19/2016
CONTROL ECOG1
8
MOS + 8 MONTHS
9/18/2016 11:54:14 AM
5/19/2017 11:48:28 PM
N
565
1/21/2016
BAVI ECOG1
12
MOS + 8 MONTHS
1/20/2017 5:51:22 AM
9/20/2017 5:45:36 PM
N
566
1/22/2016
CONTROL ECOG0
10
MOS + 8 MONTHS
11/21/2016 8:52:48 AM
7/22/2017 8:47:02 PM
N
567
1/23/2016
CONTROL ECOG1
8
MOS + 8 MONTHS
9/22/2016 11:54:14 AM
5/23/2017 11:48:28 PM
N
568
1/24/2016
BAVI ECOG0
17
MOS + 8 MONTHS
6/24/2017 10:17:46 AM
2/22/2018 10:12:00 PM
N
571
1/27/2016
CONTROL ECOG1
8
MOS + 8 MONTHS
9/26/2016 11:54:14 AM
5/27/2017 11:48:28 PM
N
572
1/28/2016
BAVI ECOG0
17
MOS + 8 MONTHS
6/28/2017 10:17:46 AM
2/26/2018 10:12:00 PM
N
573
1/29/2016
BAVI ECOG1
12
MOS + 8 MONTHS
1/28/2017 5:51:22 AM
9/28/2017 5:45:36 PM
N
67
8/24/2014
CONTROL ECOG1
8
MOS + 8 MONTHS
4/24/2015 11:54:14 AM
12/23/2015 11:48:28 PM
N
80
9/8/2014
BAVI ECOG0
17
MOS + 8 MONTHS
2/7/2016 10:17:46 AM
10/7/2016 10:12:00 PM
N
170
12/15/2014
CONTROL ECOG0
10
MOS + 8 MONTHS
10/15/2015 8:52:48 AM
6/14/2016 8:47:02 PM
N
181
12/27/2014
BAVI ECOG1
12
MOS + 8 MONTHS
12/27/2015 5:51:22 AM
8/26/2016 5:45:36 PM
N
261
3/20/2015
BAVI ECOG1
12
MOS + 8 MONTHS
3/19/2016 5:51:22 AM
11/17/2016 5:45:36 PM
N
266
3/25/2015
CONTROL ECOG0
10
MOS + 8 MONTHS
1/23/2016 8:52:48 AM
9/22/2016 8:47:02 PM
N
276
4/4/2015
BAVI ECOG0
17
MOS + 8 MONTHS
9/2/2016 10:17:46 AM
5/3/2017 10:12:00 PM
N
280
4/8/2015
BAVI ECOG0
17
MOS + 8 MONTHS
9/6/2016 10:17:46 AM
5/7/2017 10:12:00 PM
N
360
6/27/2015
BAVI ECOG0
17
MOS + 8 MONTHS
11/25/2016 10:17:46 AM
7/26/2017 10:12:00 PM
N
403
8/10/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
4/9/2016 11:54:14 AM
2/8/2016 2:55:40 PM
N
411
8/18/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
4/17/2016 11:54:14 AM
2/16/2016 2:55:40 PM
N
415
8/22/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
4/21/2016 11:54:14 AM
2/20/2016 2:55:40 PM
N
423
8/30/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
4/29/2016 11:54:14 AM
2/28/2016 2:55:40 PM
N
427
9/3/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
5/3/2016 11:54:14 AM
3/3/2016 2:55:40 PM
N
4
4/1/2014
BAVI ECOG0
17
MOS - 2 MONTHS
8/31/2015 10:17:46 AM
7/1/2015 1:19:12 PM
Y
24
6/25/2014
BAVI ECOG0
17
MOS - 2 MONTHS
11/24/2015 10:17:46 AM
9/24/2015 1:19:12 PM
N
44
7/25/2014
BAVI ECOG0
17
MOS
12/24/2015 10:17:46 AM
12/24/2015 10:17:46 AM
N
124
10/27/2014
BAVI ECOG0
17
MOS - 2 MONTHS
3/27/2016 10:17:46 AM
1/26/2016 1:19:12 PM
N
144
11/18/2014
BAVI ECOG0
17
MOS
4/18/2016 10:17:46 AM
4/18/2016 10:17:46 AM
N
164
12/9/2014
BAVI ECOG0
17
MOS + 8 MONTHS
5/9/2016 10:17:46 AM
1/7/2017 10:12:00 PM
N
188
1/3/2015
BAVI ECOG0
17
MOS + 13 MONTHS
6/3/2016 10:17:46 AM
7/4/2017 2:38:24 AM
N
208
1/24/2015
BAVI ECOG0
17
MOS - 2 MONTHS
6/24/2016 10:17:46 AM
4/24/2016 1:19:12 PM
N
228
2/14/2015
BAVI ECOG0
17
MOS - 2 MONTHS
7/15/2016 10:17:46 AM
5/15/2016 1:19:12 PM
N
248
3/6/2015
BAVI ECOG0
17
MOS
8/4/2016 10:17:46 AM
8/4/2016 10:17:46 AM
N
272
3/31/2015
BAVI ECOG0
17
MOS + 8 MONTHS
8/29/2016 10:17:46 AM
4/29/2017 10:12:00 PM
N
292
4/20/2015
BAVI ECOG0
17
MOS + 13 MONTHS
9/18/2016 10:17:46 AM
10/19/2017 2:38:24 AM
N
340
6/7/2015
BAVI ECOG0
17
MOS
11/5/2016 10:17:46 AM
11/5/2016 10:17:46 AM
N
396
8/3/2015
BAVI ECOG0
17
MOS + 15 MONTHS
1/1/2017 10:17:46 AM
4/2/2018 11:36:58 PM
N
37
7/15/2014
BAVI ECOG1
12
MOS - 2 MONTHS
7/15/2015 5:51:22 AM
5/15/2015 8:52:48 AM
N
193
1/8/2015
BAVI ECOG1
12
MOS + 13 MONTHS
1/8/2016 5:51:22 AM
2/6/2017 10:12:00 PM
N
273
4/1/2015
BAVI ECOG1
12
MOS + 8 MONTHS
3/31/2016 5:51:22 AM
11/29/2016 5:45:36 PM
N
349
6/16/2015
BAVI ECOG1
12
MOS
6/15/2016 5:51:22 AM
6/15/2016 5:51:22 AM
N
417
8/24/2015
BAVI ECOG1
12
MOS - 2 MONTHS
8/23/2016 5:51:22 AM
6/23/2016 8:52:48 AM
N
74
9/1/2014
CONTROL ECOG0
10
MOS + 8 MONTHS
7/2/2015 8:52:48 AM
3/1/2016 8:47:02 PM
N
226
2/12/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
12/13/2015 8:52:48 AM
10/13/2015 11:54:14 AM
N
386
7/24/2015
CONTROL ECOG0
10
MOS + 13 MONTHS
5/23/2016 8:52:48 AM
6/23/2017 1:13:26 AM
N
55
8/9/2014
CONTROL ECOG1
8
MOS + 3 MONTHS
4/9/2015 11:54:14 AM
7/9/2015 7:22:04 PM
Y
167
12/12/2014
CONTROL ECOG1
8
MOS + 8 MONTHS
8/12/2015 11:54:14 AM
4/11/2016 11:48:28 PM
N
259
3/18/2015
CONTROL ECOG1
8
MOS + 3 MONTHS
11/16/2015 11:54:14 AM
2/15/2016 7:22:04 PM
N
367
7/4/2015
CONTROL ECOG1
8
MOS + 8 MONTHS
3/3/2016 11:54:14 AM
11/1/2016 11:48:28 PM
N
7
4/27/2014
CONTROL ECOG1
8
MOS - 2 MONTHS
12/26/2014 11:54:14 AM
10/26/2014 2:55:40 PM
N
12
5/29/2014
BAVI ECOG0
17
MOS - 2 MONTHS
10/28/2015 10:17:46 AM
8/28/2015 1:19:12 PM
N
16
6/8/2014
BAVI ECOG0
17
MOS - 2 MONTHS
11/7/2015 10:17:46 AM
9/7/2015 1:19:12 PM
N
23
6/23/2014
CONTROL ECOG1
8
MOS - 2 MONTHS
2/21/2015 11:54:14 AM
12/22/2014 2:55:40 PM
N
30
7/5/2014
CONTROL ECOG0
10
MOS - 2 MONTHS
5/5/2015 8:52:48 AM
3/5/2015 11:54:14 AM
N
36
7/14/2014
BAVI ECOG0
17
MOS - 2 MONTHS
12/13/2015 10:17:46 AM
10/13/2015 1:19:12 PM
N
101
10/2/2014
BAVI ECOG1
12
MOS - 2 MONTHS
10/2/2015 5:51:22 AM
8/2/2015 8:52:48 AM
N
113
10/15/2014
BAVI ECOG1
12
MOS - 2 MONTHS
10/15/2015 5:51:22 AM
8/15/2015 8:52:48 AM
N
120
10/23/2014
BAVI ECOG0
17
MOS - 2 MONTHS
3/23/2016 10:17:46 AM
1/22/2016 1:19:12 PM
N
128
11/1/2014
BAVI ECOG0
17
MOS - 2 MONTHS
4/1/2016 10:17:46 AM
1/31/2016 1:19:12 PM
N
132
11/5/2014
BAVI ECOG0
17
MOS - 2 MONTHS
4/5/2016 10:17:46 AM
2/4/2016 1:19:12 PM
N
200
1/16/2015
BAVI ECOG0
17
MOS - 2 MONTHS
6/16/2016 10:17:46 AM
4/16/2016 1:19:12 PM
N
205
1/21/2015
BAVI ECOG1
12
MOS - 2 MONTHS
1/21/2016 5:51:22 AM
11/21/2015 8:52:48 AM
N
210
1/26/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
11/26/2015 8:52:48 AM
9/26/2015 11:54:14 AM
N
216
2/1/2015
BAVI ECOG0
17
MOS - 2 MONTHS
7/2/2016 10:17:46 AM
5/2/2016 1:19:12 PM
N
231
2/17/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
10/18/2015 11:54:14 AM
8/18/2015 2:55:40 PM
N
236
2/22/2015
BAVI ECOG0
17
MOS - 2 MONTHS
7/23/2016 10:17:46 AM
5/23/2016 1:19:12 PM
N
305
5/3/2015
BAVI ECOG1
12
MOS - 2 MONTHS
5/2/2016 5:51:22 AM
3/2/2016 8:52:48 AM
N
316
5/14/2015
BAVI ECOG0
17
MOS - 2 MONTHS
10/12/2016 10:17:46 AM
8/12/2016 1:19:12 PM
N
327
5/25/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
1/23/2016 11:54:14 AM
11/23/2015 2:55:40 PM
N
329
5/27/2015
BAVI ECOG1
12
MOS - 2 MONTHS
5/26/2016 5:51:22 AM
3/26/2016 8:52:48 AM
N
426
9/2/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
7/2/2016 8:52:48 AM
5/2/2016 11:54:14 AM
N
429
9/5/2015
BAVI ECOG1
12
MOS - 2 MONTHS
9/4/2016 5:51:22 AM
7/5/2016 8:52:48 AM
N
117
10/20/2014
BAVI ECOG1
12
MOS - 2 MONTHS
10/20/2015 5:51:22 AM
8/20/2015 8:52:48 AM
N
201
1/17/2015
BAVI ECOG1
12
MOS - 2 MONTHS
1/17/2016 5:51:22 AM
11/17/2015 8:52:48 AM
N
221
2/6/2015
BAVI ECOG1
12
MOS - 2 MONTHS
2/6/2016 5:51:22 AM
12/7/2015 8:52:48 AM
N
301
4/29/2015
BAVI ECOG1
12
MOS - 2 MONTHS
4/28/2016 5:51:22 AM
2/27/2016 8:52:48 AM
N
321
5/19/2015
BAVI ECOG1
12
MOS - 2 MONTHS
5/18/2016 5:51:22 AM
3/18/2016 8:52:48 AM
N
421
8/28/2015
BAVI ECOG1
12
MOS - 2 MONTHS
8/27/2016 5:51:22 AM
6/27/2016 8:52:48 AM
N
6
4/19/2014
CONTROL ECOG0
10
MOS - 2 MONTHS
2/17/2015 8:52:48 AM
12/18/2014 11:54:14 AM
N
22
6/21/2014
CONTROL ECOG0
10
MOS - 2 MONTHS
4/21/2015 8:52:48 AM
2/19/2015 11:54:14 AM
N
110
10/12/2014
CONTROL ECOG0
10
MOS - 2 MONTHS
8/12/2015 8:52:48 AM
6/12/2015 11:54:14 AM
N
126
10/29/2014
CONTROL ECOG0
10
MOS - 2 MONTHS
8/29/2015 8:52:48 AM
6/29/2015 11:54:14 AM
N
115
10/17/2014
CONTROL ECOG1
8
MOS - 2 MONTHS
6/17/2015 11:54:14 AM
4/17/2015 2:55:40 PM
N
131
11/4/2014
CONTROL ECOG1
8
MOS - 2 MONTHS
7/5/2015 11:54:14 AM
5/5/2015 2:55:40 PM
N
235
2/21/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
10/22/2015 11:54:14 AM
8/22/2015 2:55:40 PM
N
315
5/13/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
1/11/2016 11:54:14 AM
11/11/2015 2:55:40 PM
N
335
6/2/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
1/31/2016 11:54:14 AM
12/1/2015 2:55:40 PM
N
48
7/30/2014
BAVI ECOG0
17
MOS
12/29/2015 10:17:46 AM
12/29/2015 10:17:46 AM
N
346
6/13/2015
CONTROL ECOG0
10
MOS
4/12/2016 8:52:48 AM
4/12/2016 8:52:48 AM
N
345
6/12/2015
BAVI ECOG1
12
MOS
6/11/2016 5:51:22 AM
6/11/2016 5:51:22 AM
N
343
6/10/2015
CONTROL ECOG1
8
MOS
2/8/2016 11:54:14 AM
2/8/2016 11:54:14 AM
N
56
8/10/2014
BAVI ECOG0
17
MOS + 3 MONTHS
1/9/2016 10:17:46 AM
4/9/2016 5:45:36 PM
N
256
3/14/2015
BAVI ECOG0
17
MOS + 3 MONTHS
8/12/2016 10:17:46 AM
11/11/2016 5:45:36 PM
N
356
6/23/2015
BAVI ECOG0
17
MOS + 3 MONTHS
11/21/2016 10:17:46 AM
2/20/2017 5:45:36 PM
N
153
11/27/2014
BAVI ECOG1
12
MOS + 3 MONTHS
11/27/2015 5:51:22 AM
2/26/2016 1:19:12 PM
N
353
6/20/2015
BAVI ECOG1
12
MOS + 3 MONTHS
6/19/2016 5:51:22 AM
9/18/2016 1:19:12 PM
N
54
8/7/2014
CONTROL ECOG0
10
MOS + 3 MONTHS
6/7/2015 8:52:48 AM
9/6/2015 4:20:38 PM
Y
354
6/21/2015
CONTROL ECOG0
10
MOS + 3 MONTHS
4/20/2016 8:52:48 AM
7/20/2016 4:20:38 PM
N
251
3/9/2015
CONTROL ECOG1
8
MOS
11/7/2015 11:54:14 AM
11/7/2015 11:54:14 AM
N
575
7/21/2015
CONTROL ECOG1
8
MOS + 8 MONTHS
3/20/2016 11:54:14 AM
11/18/2016 11:48:28 PM
N
577
9/23/2015
BAVI ECOG1
12
MOS + 8 MONTHS
9/22/2016 5:51:22 AM
5/23/2017 5:45:36 PM
N
579
11/27/2015
CONTROL ECOG1
8
MOS + 8 MONTHS
7/27/2016 11:54:14 AM
3/27/2017 11:48:28 PM
N
580
11/27/2015
BAVI ECOG0
17
MOS + 8 MONTHS
4/27/2017 10:17:46 AM
12/26/2017 10:12:00 PM
N
582
1/30/2016
CONTROL ECOG0
10
MOS + 8 MONTHS
11/29/2016 8:52:48 AM
7/30/2017 8:47:02 PM
N
300
4/28/2015
BAVI ECOG0
17
MOS - 2 MONTHS
9/26/2016 10:17:46 AM
7/27/2016 1:19:12 PM
N
308
5/6/2015
BAVI ECOG0
17
MOS - 2 MONTHS
10/4/2016 10:17:46 AM
8/4/2016 1:19:12 PM
N
312
5/10/2015
BAVI ECOG0
17
MOS - 2 MONTHS
10/8/2016 10:17:46 AM
8/8/2016 1:19:12 PM
N
320
5/18/2015
BAVI ECOG0
17
MOS - 2 MONTHS
10/16/2016 10:17:46 AM
8/16/2016 1:19:12 PM
N
324
5/22/2015
BAVI ECOG0
17
MOS - 2 MONTHS
10/20/2016 10:17:46 AM
8/20/2016 1:19:12 PM
N
332
5/30/2015
BAVI ECOG0
17
MOS - 2 MONTHS
10/28/2016 10:17:46 AM
8/28/2016 1:19:12 PM
N
352
6/19/2015
BAVI ECOG0
17
MOS + 3 MONTHS
11/17/2016 10:17:46 AM
2/16/2017 5:45:36 PM
N
368
7/5/2015
BAVI ECOG0
17
MOS + 8 MONTHS
12/3/2016 10:17:46 AM
8/3/2017 10:12:00 PM
N
388
7/26/2015
BAVI ECOG0
17
MOS + 13 MONTHS
12/24/2016 10:17:46 AM
1/24/2018 2:38:24 AM
N
392
7/30/2015
BAVI ECOG0
17
MOS + 13 MONTHS
12/28/2016 10:17:46 AM
1/28/2018 2:38:24 AM
N
412
8/19/2015
BAVI ECOG0
17
MOS - 2 MONTHS
1/17/2017 10:17:46 AM
11/17/2016 1:19:12 PM
N
416
8/23/2015
BAVI ECOG0
17
MOS - 2 MONTHS
1/21/2017 10:17:46 AM
11/21/2016 1:19:12 PM
N
1
2/13/2014
BAVI ECOG1
12
MOS - 2 MONTHS
2/13/2015 5:51:22 AM
12/14/2014 8:52:48 AM
Y
5
4/12/2014
BAVI ECOG1
12
MOS - 2 MONTHS
4/12/2015 5:51:22 AM
2/10/2015 8:52:48 AM
N
17
6/11/2014
BAVI ECOG1
12
MOS - 2 MONTHS
6/11/2015 5:51:22 AM
4/11/2015 8:52:48 AM
N
21
6/19/2014
BAVI ECOG1
12
MOS - 2 MONTHS
6/19/2015 5:51:22 AM
4/19/2015 8:52:48 AM
N
29
7/3/2014
BAVI ECOG1
12
MOS - 2 MONTHS
7/3/2015 5:51:22 AM
5/3/2015 8:52:48 AM
N
41
7/21/2014
BAVI ECOG1
12
MOS
7/21/2015 5:51:22 AM
7/21/2015 5:51:22 AM
Y
45
7/26/2014
BAVI ECOG1
12
MOS
7/26/2015 5:51:22 AM
7/26/2015 5:51:22 AM
N
57
8/11/2014
BAVI ECOG1
12
MOS + 3 MONTHS
8/11/2015 5:51:22 AM
11/10/2015 1:19:12 PM
N
65
8/21/2014
BAVI ECOG1
12
MOS + 8 MONTHS
8/21/2015 5:51:22 AM
4/20/2016 5:45:36 PM
N
69
8/26/2014
BAVI ECOG1
12
MOS + 8 MONTHS
8/26/2015 5:51:22 AM
4/25/2016 5:45:36 PM
N
73
8/31/2014
BAVI ECOG1
12
MOS + 8 MONTHS
8/31/2015 5:51:22 AM
4/30/2016 5:45:36 PM
N
93
9/23/2014
BAVI ECOG1
12
MOS + 13 MONTHS
9/23/2015 5:51:22 AM
10/22/2016 10:12:00 PM
N
97
9/28/2014
BAVI ECOG1
12
MOS + 15 MONTHS
9/28/2015 5:51:22 AM
12/27/2016 7:10:34 PM
Y
109
10/11/2014
BAVI ECOG1
12
MOS - 2 MONTHS
10/11/2015 5:51:22 AM
8/11/2015 8:52:48 AM
N
121
10/24/2014
BAVI ECOG1
12
MOS - 2 MONTHS
10/24/2015 5:51:22 AM
8/24/2015 8:52:48 AM
N
129
11/2/2014
BAVI ECOG1
12
MOS - 2 MONTHS
11/2/2015 5:51:22 AM
9/2/2015 8:52:48 AM
N
133
11/6/2014
BAVI ECOG1
12
MOS - 2 MONTHS
11/6/2015 5:51:22 AM
9/6/2015 8:52:48 AM
N
141
11/15/2014
BAVI ECOG1
12
MOS
11/15/2015 5:51:22 AM
11/15/2015 5:51:22 AM
N
149
11/23/2014
BAVI ECOG1
12
MOS
11/23/2015 5:51:22 AM
11/23/2015 5:51:22 AM
N
165
12/10/2014
BAVI ECOG1
12
MOS + 8 MONTHS
12/10/2015 5:51:22 AM
8/9/2016 5:45:36 PM
N
177
12/23/2014
BAVI ECOG1
12
MOS + 8 MONTHS
12/23/2015 5:51:22 AM
8/22/2016 5:45:36 PM
N
197
1/12/2015
BAVI ECOG1
12
MOS + 15 MONTHS
1/12/2016 5:51:22 AM
4/12/2017 7:10:34 PM
N
209
1/25/2015
BAVI ECOG1
12
MOS - 2 MONTHS
1/25/2016 5:51:22 AM
11/25/2015 8:52:48 AM
N
217
2/2/2015
BAVI ECOG1
12
MOS - 2 MONTHS
2/2/2016 5:51:22 AM
12/3/2015 8:52:48 AM
N
241
2/27/2015
BAVI ECOG1
12
MOS
2/27/2016 5:51:22 AM
2/27/2016 5:51:22 AM
N
245
3/3/2015
BAVI ECOG1
12
MOS
3/2/2016 5:51:22 AM
3/2/2016 5:51:22 AM
N
253
3/11/2015
BAVI ECOG1
12
MOS + 3 MONTHS
3/10/2016 5:51:22 AM
6/9/2016 1:19:12 PM
N
257
3/15/2015
BAVI ECOG1
12
MOS + 3 MONTHS
3/14/2016 5:51:22 AM
6/13/2016 1:19:12 PM
N
265
3/24/2015
BAVI ECOG1
12
MOS + 8 MONTHS
3/23/2016 5:51:22 AM
11/21/2016 5:45:36 PM
N
285
4/13/2015
BAVI ECOG1
12
MOS + 13 MONTHS
4/12/2016 5:51:22 AM
5/12/2017 10:12:00 PM
N
289
4/17/2015
BAVI ECOG1
12
MOS + 13 MONTHS
4/16/2016 5:51:22 AM
5/16/2017 10:12:00 PM
N
309
5/7/2015
BAVI ECOG1
12
MOS - 2 MONTHS
5/6/2016 5:51:22 AM
3/6/2016 8:52:48 AM
N
325
5/23/2015
BAVI ECOG1
12
MOS - 2 MONTHS
5/22/2016 5:51:22 AM
3/22/2016 8:52:48 AM
N
333
5/31/2015
BAVI ECOG1
12
MOS - 2 MONTHS
5/30/2016 5:51:22 AM
3/30/2016 8:52:48 AM
N
365
7/2/2015
BAVI ECOG1
12
MOS + 8 MONTHS
7/1/2016 5:51:22 AM
3/1/2017 5:45:36 PM
N
381
7/18/2015
BAVI ECOG1
12
MOS + 8 MONTHS
7/17/2016 5:51:22 AM
3/17/2017 5:45:36 PM
N
393
7/31/2015
BAVI ECOG1
12
MOS + 13 MONTHS
7/30/2016 5:51:22 AM
8/29/2017 10:12:00 PM
N
401
8/8/2015
BAVI ECOG1
12
MOS - 2 MONTHS
8/7/2016 5:51:22 AM
6/7/2016 8:52:48 AM
N
405
8/12/2015
BAVI ECOG1
12
MOS - 2 MONTHS
8/11/2016 5:51:22 AM
6/11/2016 8:52:48 AM
N
425
9/1/2015
BAVI ECOG1
12
MOS - 2 MONTHS
8/31/2016 5:51:22 AM
7/1/2016 8:52:48 AM
N
10
5/17/2014
CONTROL ECOG0
10
MOS - 2 MONTHS
3/17/2015 8:52:48 AM
1/15/2015 11:54:14 AM
N
18
6/13/2014
CONTROL ECOG0
10
MOS - 2 MONTHS
4/13/2015 8:52:48 AM
2/11/2015 11:54:14 AM
N
26
6/28/2014
CONTROL ECOG0
10
MOS - 2 MONTHS
4/28/2015 8:52:48 AM
2/26/2015 11:54:14 AM
N
34
7/11/2014
CONTROL ECOG0
10
MOS - 2 MONTHS
5/11/2015 8:52:48 AM
3/11/2015 11:54:14 AM
N
50
8/2/2014
CONTROL ECOG0
10
MOS
6/2/2015 8:52:48 AM
6/2/2015 8:52:48 AM
N
66
8/22/2014
CONTROL ECOG0
10
MOS + 8 MONTHS
6/22/2015 8:52:48 AM
2/20/2016 8:47:02 PM
N
70
8/27/2014
CONTROL ECOG0
10
MOS + 8 MONTHS
6/27/2015 8:52:48 AM
2/25/2016 8:47:02 PM
N
78
9/6/2014
CONTROL ECOG0
10
MOS + 8 MONTHS
7/7/2015 8:52:48 AM
3/6/2016 8:47:02 PM
N
98
9/29/2014
CONTROL ECOG0
10
MOS + 15 MONTHS
7/30/2015 8:52:48 AM
10/28/2016 10:12:00 PM
Y
102
10/3/2014
CONTROL ECOG0
10
MOS - 2 MONTHS
8/3/2015 8:52:48 AM
6/3/2015 11:54:14 AM
N
114
10/16/2014
CONTROL ECOG0
10
MOS - 2 MONTHS
8/16/2015 8:52:48 AM
6/16/2015 11:54:14 AM
N
122
10/25/2014
CONTROL ECOG0
10
MOS - 2 MONTHS
8/25/2015 8:52:48 AM
6/25/2015 11:54:14 AM
N
134
11/7/2014
CONTROL ECOG0
10
MOS - 2 MONTHS
9/7/2015 8:52:48 AM
7/8/2015 11:54:14 AM
N
138
11/11/2014
CONTROL ECOG0
10
MOS
9/11/2015 8:52:48 AM
9/11/2015 8:52:48 AM
N
154
11/28/2014
CONTROL ECOG0
10
MOS + 3 MONTHS
9/28/2015 8:52:48 AM
12/28/2015 4:20:38 PM
N
162
12/7/2014
CONTROL ECOG0
10
MOS + 8 MONTHS
10/7/2015 8:52:48 AM
6/6/2016 8:47:02 PM
N
174
12/19/2014
CONTROL ECOG0
10
MOS + 8 MONTHS
10/19/2015 8:52:48 AM
6/18/2016 8:47:02 PM
N
178
12/24/2014
CONTROL ECOG0
10
MOS + 8 MONTHS
10/24/2015 8:52:48 AM
6/23/2016 8:47:02 PM
N
190
1/5/2015
CONTROL ECOG0
10
MOS + 13 MONTHS
11/5/2015 8:52:48 AM
12/5/2016 1:13:26 AM
N
194
1/9/2015
CONTROL ECOG0
10
MOS + 13 MONTHS
11/9/2015 8:52:48 AM
12/9/2016 1:13:26 AM
N
202
1/18/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
11/18/2015 8:52:48 AM
9/18/2015 11:54:14 AM
N
206
1/22/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
11/22/2015 8:52:48 AM
9/22/2015 11:54:14 AM
N
214
1/30/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
11/30/2015 8:52:48 AM
9/30/2015 11:54:14 AM
N
218
2/3/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
12/4/2015 8:52:48 AM
10/4/2015 11:54:14 AM
N
230
2/16/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
12/17/2015 8:52:48 AM
10/17/2015 11:54:14 AM
N
234
2/20/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
12/21/2015 8:52:48 AM
10/21/2015 11:54:14 AM
N
242
2/28/2015
CONTROL ECOG0
10
MOS
12/29/2015 8:52:48 AM
12/29/2015 8:52:48 AM
N
246
3/4/2015
CONTROL ECOG0
10
MOS
1/2/2016 8:52:48 AM
1/2/2016 8:52:48 AM
N
254
3/12/2015
CONTROL ECOG0
10
MOS + 3 MONTHS
1/10/2016 8:52:48 AM
4/10/2016 4:20:38 PM
N
258
3/16/2015
CONTROL ECOG0
10
MOS + 3 MONTHS
1/14/2016 8:52:48 AM
4/14/2016 4:20:38 PM
N
274
4/2/2015
CONTROL ECOG0
10
MOS + 8 MONTHS
1/31/2016 8:52:48 AM
9/30/2016 8:47:02 PM
N
282
4/10/2015
CONTROL ECOG0
10
MOS + 8 MONTHS
2/8/2016 8:52:48 AM
10/8/2016 8:47:02 PM
N
286
4/14/2015
CONTROL ECOG0
10
MOS + 13 MONTHS
2/12/2016 8:52:48 AM
3/14/2017 1:13:26 AM
N
298
4/26/2015
CONTROL ECOG0
10
MOS + 15 MONTHS
2/24/2016 8:52:48 AM
5/25/2017 10:12:00 PM
N
302
4/30/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
2/28/2016 8:52:48 AM
12/29/2015 11:54:14 AM
N
314
5/12/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
3/11/2016 8:52:48 AM
1/10/2016 11:54:14 AM
N
326
5/24/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
3/23/2016 8:52:48 AM
1/22/2016 11:54:14 AM
N
334
6/1/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
3/31/2016 8:52:48 AM
1/30/2016 11:54:14 AM
N
338
6/5/2015
CONTROL ECOG0
10
MOS
4/4/2016 8:52:48 AM
4/4/2016 8:52:48 AM
N
342
6/9/2015
CONTROL ECOG0
10
MOS
4/8/2016 8:52:48 AM
4/8/2016 8:52:48 AM
N
350
6/17/2015
CONTROL ECOG0
10
MOS
4/16/2016 8:52:48 AM
4/16/2016 8:52:48 AM
N
378
7/15/2015
CONTROL ECOG0
10
MOS + 8 MONTHS
5/14/2016 8:52:48 AM
1/12/2017 8:47:02 PM
N
390
7/28/2015
CONTROL ECOG0
10
MOS + 13 MONTHS
5/27/2016 8:52:48 AM
6/27/2017 1:13:26 AM
N
394
8/1/2015
CONTROL ECOG0
10
MOS + 13 MONTHS
5/31/2016 8:52:48 AM
7/1/2017 1:13:26 AM
N
402
8/9/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
6/8/2016 8:52:48 AM
4/8/2016 11:54:14 AM
N
406
8/13/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
6/12/2016 8:52:48 AM
4/12/2016 11:54:14 AM
N
414
8/21/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
6/20/2016 8:52:48 AM
4/20/2016 11:54:14 AM
N
418
8/25/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
6/24/2016 8:52:48 AM
4/24/2016 11:54:14 AM
N
3
3/18/2014
CONTROL ECOG1
8
MOS - 2 MONTHS
11/16/2014 11:54:14 AM
9/16/2014 2:55:40 PM
Y
11
5/23/2014
CONTROL ECOG1
8
MOS - 2 MONTHS
1/21/2015 11:54:14 AM
11/21/2014 2:55:40 PM
N
15
6/6/2014
CONTROL ECOG1
8
MOS - 2 MONTHS
2/4/2015 11:54:14 AM
12/5/2014 2:55:40 PM
N
19
6/15/2014
CONTROL ECOG1
8
MOS - 2 MONTHS
2/13/2015 11:54:14 AM
12/14/2014 2:55:40 PM
N
27
6/30/2014
CONTROL ECOG1
8
MOS - 2 MONTHS
2/28/2015 11:54:14 AM
12/29/2014 2:55:40 PM
N
35
7/12/2014
CONTROL ECOG1
8
MOS - 2 MONTHS
3/12/2015 11:54:14 AM
1/10/2015 2:55:40 PM
N
43
7/24/2014
CONTROL ECOG1
8
MOS
3/24/2015 11:54:14 AM
3/24/2015 11:54:14 AM
N
47
7/29/2014
CONTROL ECOG1
8
MOS
3/29/2015 11:54:14 AM
3/29/2015 11:54:14 AM
N
51
8/3/2014
CONTROL ECOG1
8
MOS
4/3/2015 11:54:14 AM
4/3/2015 11:54:14 AM
N
59
8/14/2014
CONTROL ECOG1
8
MOS + 3 MONTHS
4/14/2015 11:54:14 AM
7/14/2015 7:22:04 PM
N
63
8/19/2014
CONTROL ECOG1
8
MOS + 8 MONTHS
4/19/2015 11:54:14 AM
12/18/2015 11:48:28 PM
Y
71
8/28/2014
CONTROL ECOG1
8
MOS + 8 MONTHS
4/28/2015 11:54:14 AM
12/27/2015 11:48:28 PM
N
103
10/4/2014
CONTROL ECOG1
8
MOS - 2 MONTHS
6/4/2015 11:54:14 AM
4/4/2015 2:55:40 PM
N
107
10/9/2014
CONTROL ECOG1
8
MOS - 2 MONTHS
6/9/2015 11:54:14 AM
4/9/2015 2:55:40 PM
N
123
10/26/2014
CONTROL ECOG1
8
MOS - 2 MONTHS
6/26/2015 11:54:14 AM
4/26/2015 2:55:40 PM
N
143
11/17/2014
CONTROL ECOG1
8
MOS
7/18/2015 11:54:14 AM
7/18/2015 11:54:14 AM
N
159
12/4/2014
CONTROL ECOG1
8
MOS + 3 MONTHS
8/4/2015 11:54:14 AM
11/3/2015 7:22:04 PM
N
171
12/16/2014
CONTROL ECOG1
8
MOS + 8 MONTHS
8/16/2015 11:54:14 AM
4/15/2016 11:48:28 PM
N
175
12/21/2014
CONTROL ECOG1
8
MOS + 8 MONTHS
8/21/2015 11:54:14 AM
4/20/2016 11:48:28 PM
N
199
1/15/2015
CONTROL ECOG1
8
MOS + 15 MONTHS
9/15/2015 11:54:14 AM
12/15/2016 1:13:26 AM
N
203
1/19/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
9/19/2015 11:54:14 AM
7/20/2015 2:55:40 PM
N
211
1/27/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
9/27/2015 11:54:14 AM
7/28/2015 2:55:40 PM
N
223
2/8/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
10/9/2015 11:54:14 AM
8/9/2015 2:55:40 PM
N
227
2/13/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
10/14/2015 11:54:14 AM
8/14/2015 2:55:40 PM
N
239
2/25/2015
CONTROL ECOG1
8
MOS
10/26/2015 11:54:14 AM
10/26/2015 11:54:14 AM
N
243
3/1/2015
CONTROL ECOG1
8
MOS
10/30/2015 11:54:14 AM
10/30/2015 11:54:14 AM
N
263
3/22/2015
CONTROL ECOG1
8
MOS + 8 MONTHS
11/20/2015 11:54:14 AM
7/20/2016 11:48:28 PM
N
279
4/7/2015
CONTROL ECOG1
8
MOS + 8 MONTHS
12/6/2015 11:54:14 AM
8/5/2016 11:48:28 PM
N
283
4/11/2015
CONTROL ECOG1
8
MOS + 13 MONTHS
12/10/2015 11:54:14 AM
1/9/2017 4:14:52 AM
N
291
4/19/2015
CONTROL ECOG1
8
MOS + 13 MONTHS
12/18/2015 11:54:14 AM
1/17/2017 4:14:52 AM
N
295
4/23/2015
CONTROL ECOG1
8
MOS + 15 MONTHS
12/22/2015 11:54:14 AM
3/23/2017 1:13:26 AM
N
307
5/5/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
1/3/2016 11:54:14 AM
11/3/2015 2:55:40 PM
N
319
5/17/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
1/15/2016 11:54:14 AM
11/15/2015 2:55:40 PM
N
331
5/29/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
1/27/2016 11:54:14 AM
11/27/2015 2:55:40 PM
N
347
6/14/2015
CONTROL ECOG1
8
MOS
2/12/2016 11:54:14 AM
2/12/2016 11:54:14 AM
N
355
6/22/2015
CONTROL ECOG1
8
MOS + 3 MONTHS
2/20/2016 11:54:14 AM
5/21/2016 7:22:04 PM
N
363
6/30/2015
CONTROL ECOG1
8
MOS + 8 MONTHS
2/28/2016 11:54:14 AM
10/28/2016 11:48:28 PM
N
387
7/25/2015
CONTROL ECOG1
8
MOS + 13 MONTHS
3/24/2016 11:54:14 AM
4/24/2017 4:14:52 AM
N
576
7/21/2015
BAVI ECOG0
17
MOS + 8 MONTHS
12/19/2016 10:17:46 AM
8/19/2017 10:12:00 PM
N
578
9/23/2015
CONTROL ECOG0
10
MOS + 8 MONTHS
7/23/2016 8:52:48 AM
3/23/2017 8:47:02 PM
N
581
1/30/2016
BAVI ECOG1
12
MOS + 8 MONTHS
1/29/2017 5:51:22 AM
9/29/2017 5:45:36 PM
N
364
7/1/2015
BAVI ECOG0
17
MOS + 8 MONTHS
11/29/2016 10:17:46 AM
7/30/2017 10:12:00 PM
N
380
7/17/2015
BAVI ECOG0
17
MOS + 8 MONTHS
12/15/2016 10:17:46 AM
8/15/2017 10:12:00 PM
N
81
9/9/2014
BAVI ECOG1
12
MOS + 8 MONTHS
9/9/2015 5:51:22 AM
5/9/2016 5:45:36 PM
N
173
12/18/2014
BAVI ECOG1
12
MOS + 8 MONTHS
12/18/2015 5:51:22 AM
8/17/2016 5:45:36 PM
N
269
3/28/2015
BAVI ECOG1
12
MOS + 8 MONTHS
3/27/2016 5:51:22 AM
11/25/2016 5:45:36 PM
N
369
7/6/2015
BAVI ECOG1
12
MOS + 8 MONTHS
7/5/2016 5:51:22 AM
3/5/2017 5:45:36 PM
N
62
8/17/2014
CONTROL ECOG0
10
MOS + 8 MONTHS
6/17/2015 8:52:48 AM
2/15/2016 8:47:02 PM
Y
82
9/10/2014
CONTROL ECOG0
10
MOS + 8 MONTHS
7/11/2015 8:52:48 AM
3/10/2016 8:47:02 PM
N
166
12/11/2014
CONTROL ECOG0
10
MOS + 8 MONTHS
10/11/2015 8:52:48 AM
6/10/2016 8:47:02 PM
N
182
12/28/2014
CONTROL ECOG0
10
MOS + 8 MONTHS
10/28/2015 8:52:48 AM
6/27/2016 8:47:02 PM
N
270
3/29/2015
CONTROL ECOG0
10
MOS + 8 MONTHS
1/27/2016 8:52:48 AM
9/26/2016 8:47:02 PM
N
366
7/3/2015
CONTROL ECOG0
10
MOS + 8 MONTHS
5/2/2016 8:52:48 AM
12/31/2016 8:47:02 PM
N
382
7/19/2015
CONTROL ECOG0
10
MOS + 8 MONTHS
5/18/2016 8:52:48 AM
1/16/2017 8:47:02 PM
N
75
9/2/2014
CONTROL ECOG1
8
MOS + 8 MONTHS
5/3/2015 11:54:14 AM
1/1/2016 11:48:28 PM
N
163
12/8/2014
CONTROL ECOG1
8
MOS + 8 MONTHS
8/8/2015 11:54:14 AM
4/7/2016 11:48:28 PM
N
267
3/26/2015
CONTROL ECOG1
8
MOS + 8 MONTHS
11/24/2015 11:54:14 AM
7/24/2016 11:48:28 PM
N
359
6/26/2015
CONTROL ECOG1
8
MOS + 3 MONTHS
2/24/2016 11:54:14 AM
5/25/2016 7:22:04 PM
N
375
7/12/2015
CONTROL ECOG1
8
MOS + 8 MONTHS
3/11/2016 11:54:14 AM
11/9/2016 11:48:28 PM
N
88
9/17/2014
BAVI ECOG0
17
MOS + 13 MONTHS
2/16/2016 10:17:46 AM
3/18/2017 2:38:24 AM
N
186
1/1/2015
CONTROL ECOG0
10
MOS + 13 MONTHS
11/1/2015 8:52:48 AM
12/1/2016 1:13:26 AM
N
192
1/7/2015
BAVI ECOG0
17
MOS + 13 MONTHS
6/7/2016 10:17:46 AM
7/8/2017 2:38:24 AM
N
288
4/16/2015
BAVI ECOG0
17
MOS + 13 MONTHS
9/14/2016 10:17:46 AM
10/15/2017 2:38:24 AM
N
293
4/21/2015
BAVI ECOG1
12
MOS + 13 MONTHS
4/20/2016 5:51:22 AM
5/20/2017 10:12:00 PM
N
385
7/23/2015
BAVI ECOG1
12
MOS + 13 MONTHS
7/22/2016 5:51:22 AM
8/21/2017 10:12:00 PM
N
85
9/14/2014
BAVI ECOG1
12
MOS + 13 MONTHS
9/14/2015 5:51:22 AM
10/13/2016 10:12:00 PM
Y
189
1/4/2015
BAVI ECOG1
12
MOS + 13 MONTHS
1/4/2016 5:51:22 AM
2/2/2017 10:12:00 PM
N
94
9/24/2014
CONTROL ECOG0
10
MOS + 13 MONTHS
7/25/2015 8:52:48 AM
8/24/2016 1:13:26 AM
N
294
4/22/2015
CONTROL ECOG0
10
MOS + 13 MONTHS
2/20/2016 8:52:48 AM
3/22/2017 1:13:26 AM
N
87
9/16/2014
CONTROL ECOG1
8
MOS + 13 MONTHS
5/17/2015 11:54:14 AM
6/16/2016 4:14:52 AM
N
187
1/2/2015
CONTROL ECOG1
8
MOS + 13 MONTHS
9/2/2015 11:54:14 AM
10/2/2016 4:14:52 AM
N
96
9/26/2014
BAVI ECOG0
17
MOS + 15 MONTHS
2/25/2016 10:17:46 AM
5/26/2017 11:36:58 PM
Y
198
1/14/2015
CONTROL ECOG0
10
MOS + 15 MONTHS
11/14/2015 8:52:48 AM
2/12/2017 10:12:00 PM
N
299
4/27/2015
CONTROL ECOG1
8
MOS + 15 MONTHS
12/26/2015 11:54:14 AM
3/27/2017 1:13:26 AM
N
297
4/25/2015
BAVI ECOG1
12
MOS + 15 MONTHS
4/24/2016 5:51:22 AM
7/24/2017 7:10:34 PM
N
195
1/10/2015
CONTROL ECOG1
8
MOS + 15 MONTHS
9/10/2015 11:54:14 AM
12/10/2016 1:13:26 AM
N
395
8/2/2015
CONTROL ECOG1
8
MOS + 15 MONTHS
4/1/2016 11:54:14 AM
7/2/2017 1:13:26 AM
N
8
5/3/2014
BAVI ECOG0
17
MOS - 2 MONTHS
10/2/2015 10:17:46 AM
8/2/2015 1:19:12 PM
N
28
7/2/2014
BAVI ECOG0
17
MOS - 2 MONTHS
12/1/2015 10:17:46 AM
10/1/2015 1:19:12 PM
N
49
8/1/2014
BAVI ECOG1
12
MOS
8/1/2015 5:51:22 AM
8/1/2015 5:51:22 AM
N
68
8/25/2014
BAVI ECOG0
17
MOS + 8 MONTHS
1/24/2016 10:17:46 AM
9/23/2016 10:12:00 PM
N
99
9/30/2014
CONTROL ECOG1
8
MOS + 15 MONTHS
5/31/2015 11:54:14 AM
8/30/2016 1:13:26 AM
N
116
10/19/2014
BAVI ECOG0
17
MOS - 2 MONTHS
3/19/2016 10:17:46 AM
1/18/2016 1:19:12 PM
N
139
11/12/2014
CONTROL ECOG1
8
MOS
7/13/2015 11:54:14 AM
7/13/2015 11:54:14 AM
N
151
11/25/2014
CONTROL ECOG1
8
MOS
7/26/2015 11:54:14 AM
7/26/2015 11:54:14 AM
N
172
12/17/2014
BAVI ECOG0
17
MOS + 8 MONTHS
5/17/2016 10:17:46 AM
1/15/2017 10:12:00 PM
N
204
1/20/2015
BAVI ECOG0
17
MOS - 2 MONTHS
6/20/2016 10:17:46 AM
4/20/2016 1:19:12 PM
N
224
2/10/2015
BAVI ECOG0
17
MOS - 2 MONTHS
7/11/2016 10:17:46 AM
5/11/2016 1:19:12 PM
N
247
3/5/2015
CONTROL ECOG1
8
MOS
11/3/2015 11:54:14 AM
11/3/2015 11:54:14 AM
N
264
3/23/2015
BAVI ECOG0
17
MOS + 8 MONTHS
8/21/2016 10:17:46 AM
4/21/2017 10:12:00 PM
N
284
4/12/2015
BAVI ECOG0
17
MOS + 13 MONTHS
9/10/2016 10:17:46 AM
10/11/2017 2:38:24 AM
N
317
5/15/2015
BAVI ECOG1
12
MOS - 2 MONTHS
5/14/2016 5:51:22 AM
3/14/2016 8:52:48 AM
N
341
6/8/2015
BAVI ECOG1
12
MOS
6/7/2016 5:51:22 AM
6/7/2016 5:51:22 AM
N
361
6/28/2015
BAVI ECOG1
12
MOS + 8 MONTHS
6/27/2016 5:51:22 AM
2/25/2017 5:45:36 PM
N
431
9/7/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
5/7/2016 11:54:14 AM
3/7/2016 2:55:40 PM
N
478
10/25/2015
CONTROL ECOG0
10
MOS + 8 MONTHS
8/24/2016 8:52:48 AM
4/24/2017 8:47:02 PM
N
484
10/31/2015
BAVI ECOG0
17
MOS + 13 MONTHS
3/31/2017 10:17:46 AM
5/1/2018 2:38:24 AM
N
495
11/11/2015
CONTROL ECOG1
8
MOS + 15 MONTHS
7/11/2016 11:54:14 AM
10/11/2017 1:13:26 AM
N
501
11/17/2015
BAVI ECOG1
12
MOS - 2 MONTHS
11/16/2016 5:51:22 AM
9/16/2016 8:52:48 AM
N
506
11/22/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
9/21/2016 8:52:48 AM
7/22/2016 11:54:14 AM
N
512
11/29/2015
BAVI ECOG0
17
MOS - 2 MONTHS
4/29/2017 10:17:46 AM
2/27/2017 1:19:12 PM
N
517
12/4/2015
BAVI ECOG1
12
MOS - 2 MONTHS
12/3/2016 5:51:22 AM
10/3/2016 8:52:48 AM
N
523
12/10/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
8/9/2016 11:54:14 AM
6/9/2016 2:55:40 PM
N
528
12/15/2015
BAVI ECOG0
17
MOS - 2 MONTHS
5/15/2017 10:17:46 AM
3/15/2017 1:19:12 PM
N
534
12/21/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
10/20/2016 8:52:48 AM
8/20/2016 11:54:14 AM
N
544
12/31/2015
BAVI ECOG0
17
MOS
5/31/2017 10:17:46 AM
5/31/2017 10:17:46 AM
N
548
1/4/2016
BAVI ECOG0
17
MOS
6/4/2017 10:17:46 AM
6/4/2017 10:17:46 AM
N
552
1/8/2016
BAVI ECOG0
17
MOS + 3 MONTHS
6/8/2017 10:17:46 AM
9/7/2017 5:45:36 PM
N
558
1/14/2016
CONTROL ECOG0
10
MOS + 3 MONTHS
11/13/2016 8:52:48 AM
2/12/2017 4:20:38 PM
N
564
1/20/2016
BAVI ECOG0
17
MOS + 8 MONTHS
6/20/2017 10:17:46 AM
2/18/2018 10:12:00 PM
N
569
1/25/2016
BAVI ECOG1
12
MOS + 8 MONTHS
1/24/2017 5:51:22 AM
9/24/2017 5:45:36 PM
N
574
1/31/2016
CONTROL ECOG0
10
MOS + 8 MONTHS
11/30/2016 8:52:48 AM
7/31/2017 8:47:02 PM
N
176
12/22/2014
BAVI ECOG0
17
MOS + 8 MONTHS
5/22/2016 10:17:46 AM
1/20/2017 10:12:00 PM
N
370
7/7/2015
CONTROL ECOG0
10
MOS + 8 MONTHS
5/6/2016 8:52:48 AM
1/4/2017 8:47:02 PM
N
238
2/24/2015
CONTROL ECOG0
10
MOS
12/25/2015 8:52:48 AM
12/25/2015 8:52:48 AM
N
250
3/8/2015
CONTROL ECOG0
10
MOS
1/6/2016 8:52:48 AM
1/6/2016 8:52:48 AM
N
60
8/15/2014
BAVI ECOG0
17
MOS + 8 MONTHS
1/14/2016 10:17:46 AM
9/13/2016 10:12:00 PM
Y
336
6/3/2015
BAVI ECOG0
17
MOS - 2 MONTHS
11/1/2016 10:17:46 AM
9/1/2016 1:19:12 PM
N
400
8/7/2015
BAVI ECOG0
17
MOS - 2 MONTHS
1/5/2017 10:17:46 AM
11/5/2016 1:19:12 PM
N
9
5/10/2014
BAVI ECOG1
12
MOS - 2 MONTHS
5/10/2015 5:51:22 AM
3/10/2015 8:52:48 AM
N
53
8/6/2014
BAVI ECOG1
12
MOS + 3 MONTHS
8/6/2015 5:51:22 AM
11/5/2015 1:19:12 PM
Y
105
10/6/2014
BAVI ECOG1
12
MOS - 2 MONTHS
10/6/2015 5:51:22 AM
8/6/2015 8:52:48 AM
N
161
12/6/2014
BAVI ECOG1
12
MOS + 8 MONTHS
12/6/2015 5:51:22 AM
8/5/2016 5:45:36 PM
N
229
2/15/2015
BAVI ECOG1
12
MOS - 2 MONTHS
2/15/2016 5:51:22 AM
12/16/2015 8:52:48 AM
N
277
4/5/2015
BAVI ECOG1
12
MOS + 8 MONTHS
4/4/2016 5:51:22 AM
12/3/2016 5:45:36 PM
N
357
6/24/2015
BAVI ECOG1
12
MOS + 3 MONTHS
6/23/2016 5:51:22 AM
9/22/2016 1:19:12 PM
N
413
8/20/2015
BAVI ECOG1
12
MOS - 2 MONTHS
8/19/2016 5:51:22 AM
6/19/2016 8:52:48 AM
N
38
7/17/2014
CONTROL ECOG0
10
MOS
5/17/2015 8:52:48 AM
5/17/2015 8:52:48 AM
Y
86
9/15/2014
CONTROL ECOG0
10
MOS + 13 MONTHS
7/16/2015 8:52:48 AM
8/15/2016 1:13:26 AM
Y
142
11/16/2014
CONTROL ECOG0
10
MOS
9/16/2015 8:52:48 AM
9/16/2015 8:52:48 AM
N
222
2/7/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
12/8/2015 8:52:48 AM
10/8/2015 11:54:14 AM
N
262
3/21/2015
CONTROL ECOG0
10
MOS + 8 MONTHS
1/19/2016 8:52:48 AM
9/18/2016 8:47:02 PM
N
322
5/20/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
3/19/2016 8:52:48 AM
1/18/2016 11:54:14 AM
N
374
7/11/2015
CONTROL ECOG0
10
MOS + 8 MONTHS
5/10/2016 8:52:48 AM
1/8/2017 8:47:02 PM
N
422
8/29/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
6/28/2016 8:52:48 AM
4/28/2016 11:54:14 AM
N
31
7/6/2014
CONTROL ECOG1
8
MOS - 2 MONTHS
3/6/2015 11:54:14 AM
1/4/2015 2:55:40 PM
N
79
9/7/2014
CONTROL ECOG1
8
MOS + 8 MONTHS
5/8/2015 11:54:14 AM
1/6/2016 11:48:28 PM
N
135
11/8/2014
CONTROL ECOG1
8
MOS - 2 MONTHS
7/9/2015 11:54:14 AM
5/9/2015 2:55:40 PM
N
183
12/29/2014
CONTROL ECOG1
8
MOS + 13 MONTHS
8/29/2015 11:54:14 AM
9/28/2016 4:14:52 AM
N
255
3/13/2015
CONTROL ECOG1
8
MOS + 3 MONTHS
11/11/2015 11:54:14 AM
2/10/2016 7:22:04 PM
N
303
5/1/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
12/30/2015 11:54:14 AM
10/30/2015 2:55:40 PM
N
371
7/8/2015
CONTROL ECOG1
8
MOS + 8 MONTHS
3/7/2016 11:54:14 AM
11/5/2016 11:48:28 PM
N
100
10/1/2014
BAVI ECOG0
17
MOS - 2 MONTHS
3/1/2016 10:17:46 AM
12/31/2015 1:19:12 PM
N
130
11/3/2014
CONTROL ECOG0
10
MOS - 2 MONTHS
9/3/2015 8:52:48 AM
7/4/2015 11:54:14 AM
N
225
2/11/2015
BAVI ECOG1
12
MOS - 2 MONTHS
2/11/2016 5:51:22 AM
12/12/2015 8:52:48 AM
N
328
5/26/2015
BAVI ECOG0
17
MOS - 2 MONTHS
10/24/2016 10:17:46 AM
8/24/2016 1:19:12 PM
N
500
11/16/2015
BAVI ECOG0
17
MOS - 2 MONTHS
4/16/2017 10:17:46 AM
2/14/2017 1:19:12 PM
N
509
11/25/2015
BAVI ECOG1
12
MOS - 2 MONTHS
11/24/2016 5:51:22 AM
9/24/2016 8:52:48 AM
N
516
12/3/2015
BAVI ECOG0
17
MOS - 2 MONTHS
5/3/2017 10:17:46 AM
3/3/2017 1:19:12 PM
N
525
12/12/2015
BAVI ECOG1
12
MOS - 2 MONTHS
12/11/2016 5:51:22 AM
10/11/2016 8:52:48 AM
N
532
12/19/2015
BAVI ECOG0
17
MOS - 2 MONTHS
5/19/2017 10:17:46 AM
3/19/2017 1:19:12 PM
N
104
10/5/2014
BAVI ECOG0
17
MOS - 2 MONTHS
3/5/2016 10:17:46 AM
1/4/2016 1:19:12 PM
N
306
5/4/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
3/3/2016 8:52:48 AM
1/2/2016 11:54:14 AM
N
111
10/13/2014
CONTROL ECOG1
8
MOS - 2 MONTHS
6/13/2015 11:54:14 AM
4/13/2015 2:55:40 PM
N
220
2/5/2015
BAVI ECOG0
17
MOS - 2 MONTHS
7/6/2016 10:17:46 AM
5/6/2016 1:19:12 PM
N
410
8/17/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
6/16/2016 8:52:48 AM
4/16/2016 11:54:14 AM
N
337
6/4/2015
BAVI ECOG1
12
MOS - 2 MONTHS
6/3/2016 5:51:22 AM
4/3/2016 8:52:48 AM
N
215
1/31/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
10/1/2015 11:54:14 AM
8/1/2015 2:55:40 PM
N
404
8/11/2015
BAVI ECOG0
17
MOS - 2 MONTHS
1/9/2017 10:17:46 AM
11/9/2016 1:19:12 PM
N
33
7/9/2014
BAVI ECOG1
12
MOS - 2 MONTHS
7/9/2015 5:51:22 AM
5/9/2015 8:52:48 AM
N
233
2/19/2015
BAVI ECOG1
12
MOS - 2 MONTHS
2/19/2016 5:51:22 AM
12/20/2015 8:52:48 AM
N
2
3/2/2014
CONTROL ECOG0
10
MOS - 2 MONTHS
12/31/2014 8:52:48 AM
10/31/2014 11:54:14 AM
Y
310
5/8/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
3/7/2016 8:52:48 AM
1/6/2016 11:54:14 AM
N
430
9/6/2015
CONTROL ECOG0
10
MOS - 2 MONTHS
7/6/2016 8:52:48 AM
5/6/2016 11:54:14 AM
N
119
10/22/2014
CONTROL ECOG1
8
MOS - 2 MONTHS
6/22/2015 11:54:14 AM
4/22/2015 2:55:40 PM
N
323
5/21/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
1/19/2016 11:54:14 AM
11/19/2015 2:55:40 PM
N
39
7/18/2014
CONTROL ECOG1
8
MOS
3/18/2015 11:54:14 AM
3/18/2015 11:54:14 AM
Y
148
11/22/2014
BAVI ECOG0
17
MOS
4/22/2016 10:17:46 AM
4/22/2016 10:17:46 AM
N
348
6/15/2015
BAVI ECOG0
17
MOS
11/13/2016 10:17:46 AM
11/13/2016 10:17:46 AM
N
440
9/16/2015
BAVI ECOG0
17
MOS
2/14/2017 10:17:46 AM
2/14/2017 10:17:46 AM
N
445
9/21/2015
BAVI ECOG1
12
MOS
9/20/2016 5:51:22 AM
9/20/2016 5:51:22 AM
N
538
12/25/2015
CONTROL ECOG0
10
MOS
10/24/2016 8:52:48 AM
10/24/2016 8:52:48 AM
N
545
1/1/2016
BAVI ECOG1
12
MOS
12/31/2016 5:51:22 AM
12/31/2016 5:51:22 AM
N
146
11/20/2014
CONTROL ECOG0
10
MOS
9/20/2015 8:52:48 AM
9/20/2015 8:52:48 AM
N
344
6/11/2015
BAVI ECOG0
17
MOS
11/9/2016 10:17:46 AM
11/9/2016 10:17:46 AM
N
42
7/22/2014
CONTROL ECOG0
10
MOS
5/22/2015 8:52:48 AM
5/22/2015 8:52:48 AM
N
147
11/21/2014
CONTROL ECOG1
8
MOS
7/22/2015 11:54:14 AM
7/22/2015 11:54:14 AM
N
351
6/18/2015
CONTROL ECOG1
8
MOS
2/16/2016 11:54:14 AM
2/16/2016 11:54:14 AM
N
451
9/28/2015
CONTROL ECOG1
8
MOS
5/28/2016 11:54:14 AM
5/28/2016 11:54:14 AM
N
550
1/6/2016
CONTROL ECOG0
10
MOS
11/5/2016 8:52:48 AM
11/5/2016 8:52:48 AM
N
152
11/26/2014
BAVI ECOG0
17
MOS + 3 MONTHS
4/26/2016 10:17:46 AM
7/26/2016 5:45:36 PM
N
150
11/24/2014
CONTROL ECOG0
10
MOS
9/24/2015 8:52:48 AM
9/24/2015 8:52:48 AM
N
155
11/29/2014
CONTROL ECOG1
8
MOS + 3 MONTHS
7/30/2015 11:54:14 AM
10/29/2015 7:22:04 PM
N
169
12/14/2014
BAVI ECOG1
12
MOS + 8 MONTHS
12/14/2015 5:51:22 AM
8/13/2016 5:45:36 PM
N
278
4/6/2015
CONTROL ECOG0
10
MOS + 8 MONTHS
2/4/2016 8:52:48 AM
10/4/2016 8:47:02 PM
N
458
10/5/2015
CONTROL ECOG0
10
MOS + 3 MONTHS
8/4/2016 8:52:48 AM
11/3/2016 4:20:38 PM
N
465
10/12/2015
BAVI ECOG1
12
MOS + 8 MONTHS
10/11/2016 5:51:22 AM
6/11/2017 5:45:36 PM
N
471
10/18/2015
CONTROL ECOG1
8
MOS + 8 MONTHS
6/17/2016 11:54:14 AM
2/15/2017 11:48:28 PM
N
479
10/26/2015
CONTROL ECOG1
8
MOS + 8 MONTHS
6/25/2016 11:54:14 AM
2/23/2017 11:48:28 PM
N
562
1/18/2016
CONTROL ECOG0
10
MOS + 8 MONTHS
11/17/2016 8:52:48 AM
7/18/2017 8:47:02 PM
N
570
1/26/2016
CONTROL ECOG0
10
MOS + 8 MONTHS
11/25/2016 8:52:48 AM
7/26/2017 8:47:02 PM
N
160
12/5/2014
BAVI ECOG0
17
MOS + 8 MONTHS
5/5/2016 10:17:46 AM
1/3/2017 10:12:00 PM
N
379
7/16/2015
CONTROL ECOG1
8
MOS + 8 MONTHS
3/15/2016 11:54:14 AM
11/13/2016 11:48:28 PM
N
64
8/20/2014
BAVI ECOG0
17
MOS + 8 MONTHS
1/19/2016 10:17:46 AM
9/18/2016 10:12:00 PM
N
376
7/13/2015
BAVI ECOG0
17
MOS + 8 MONTHS
12/11/2016 10:17:46 AM
8/11/2017 10:12:00 PM
N
377
7/14/2015
BAVI ECOG1
12
MOS + 8 MONTHS
7/13/2016 5:51:22 AM
3/13/2017 5:45:36 PM
N
362
6/29/2015
CONTROL ECOG0
10
MOS + 8 MONTHS
4/28/2016 8:52:48 AM
12/27/2016 8:47:02 PM
N
275
4/3/2015
CONTROL ECOG1
8
MOS + 8 MONTHS
12/2/2015 11:54:14 AM
8/1/2016 11:48:28 PM
N
92
9/22/2014
BAVI ECOG0
17
MOS + 13 MONTHS
2/21/2016 10:17:46 AM
3/23/2017 2:38:24 AM
N
493
11/9/2015
BAVI ECOG1
12
MOS + 13 MONTHS
11/8/2016 5:51:22 AM
12/8/2017 10:12:00 PM
N
84
9/13/2014
BAVI ECOG0
17
MOS + 13 MONTHS
2/12/2016 10:17:46 AM
3/14/2017 2:38:24 AM
Y
185
12/31/2014
BAVI ECOG1
12
MOS + 13 MONTHS
12/31/2015 5:51:22 AM
1/29/2017 10:12:00 PM
N
91
9/21/2014
CONTROL ECOG1
8
MOS + 13 MONTHS
5/22/2015 11:54:14 AM
6/21/2016 4:14:52 AM
N
90
9/20/2014
CONTROL ECOG0
10
MOS + 13 MONTHS
7/21/2015 8:52:48 AM
8/20/2016 1:13:26 AM
N
389
7/27/2015
BAVI ECOG1
12
MOS + 13 MONTHS
7/26/2016 5:51:22 AM
8/25/2017 10:12:00 PM
N
489
11/5/2015
BAVI ECOG1
12
MOS + 13 MONTHS
11/4/2016 5:51:22 AM
12/4/2017 10:12:00 PM
N
196
1/11/2015
BAVI ECOG0
17
MOS + 15 MONTHS
6/11/2016 10:17:46 AM
9/10/2017 11:36:58 PM
N
399
8/6/2015
CONTROL ECOG1
8
MOS + 15 MONTHS
4/5/2016 11:54:14 AM
7/6/2017 1:13:26 AM
N
398
8/5/2015
CONTROL ECOG0
10
MOS + 15 MONTHS
6/4/2016 8:52:48 AM
9/3/2017 10:12:00 PM
N
108
10/10/2014
BAVI ECOG0
17
MOS - 2 MONTHS
3/10/2016 10:17:46 AM
1/9/2016 1:19:12 PM
N
268
3/27/2015
BAVI ECOG0
17
MOS + 8 MONTHS
8/25/2016 10:17:46 AM
4/25/2017 10:12:00 PM
N
439
9/15/2015
CONTROL ECOG1
8
MOS
5/15/2016 11:54:14 AM
5/15/2016 11:54:14 AM
N
466
10/13/2015
CONTROL ECOG0
10
MOS + 8 MONTHS
8/12/2016 8:52:48 AM
4/12/2017 8:47:02 PM
N
504
11/20/2015
BAVI ECOG0
17
MOS - 2 MONTHS
4/20/2017 10:17:46 AM
2/18/2017 1:19:12 PM
N
543
12/30/2015
CONTROL ECOG1
8
MOS
8/29/2016 11:54:14 AM
8/29/2016 11:54:14 AM
N
76
9/3/2014
BAVI ECOG0
17
MOS + 8 MONTHS
2/2/2016 10:17:46 AM
10/2/2016 10:12:00 PM
N
125
10/28/2014
BAVI ECOG1
12
MOS - 2 MONTHS
10/28/2015 5:51:22 AM
8/28/2015 8:52:48 AM
N
407
8/14/2015
CONTROL ECOG1
8
MOS - 2 MONTHS
4/13/2016 11:54:14 AM
2/12/2016 2:55:40 PM
N
424
8/31/2015
BAVI ECOG0
17
MOS - 2 MONTHS
1/29/2017 10:17:46 AM
11/29/2016 1:19:12 PM
N
313
5/11/2015
BAVI ECOG1
12
MOS - 2 MONTHS
5/10/2016 5:51:22 AM
3/10/2016 8:52:48 AM
N
95
9/25/2014
CONTROL ECOG1
8
MOS + 15 MONTHS
5/26/2015 11:54:14 AM
8/25/2016 1:13:26 AM
Y
383
7/20/2015
CONTROL ECOG1
8
MOS + 13 MONTHS
3/19/2016 11:54:14 AM
4/19/2017 4:14:52 AM
N

JQ I imported cp's spreadsheet into a database and applied a distribution curve based on what I saw on the asco 2013 poster. I will add in 8 random dropouts in each arm next week to the simulation and let you know where we might be at next week. As of now, based on cp's enrollment chart and the .8*.3*582 first look in posted by ex and no first look in press released - I'm getting a possible 10 vs15 MOS so far.

Krak - I added too - 10k shares at .88 this morn - we are both either brilliant or brilliantly crazy! Good luck to all of us!

Cheynew - those shorts aren't getting my shares when they need to cover! I'm thinking of buying some more today to match Jeff - am I crazy or brilliant?