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Paulness and all CYGX'ers..............the last paragraph of the target validation service at Cytogenix website has the clause plainly stated................"target Validation services are provided under a service contract that includes mutual confidentiality clauses"...................so !
this could answer a question I have had for the past year,
how has CYGX been paying for the research work, new labs and facilities, etc.
CYGX could be generating a fairly good income to cover these things and the contracts are mutually confidential.
Of course this should show up at some point as generated income.
Good post, Paulness !
Neo/Peace..........great conclusions there!
When you consider the impt. of a safe Rx for HSV, $80,000 doesn't set my world on fire ! It never made sense.
What may have happen here as Peace has pointed out, is PP expected CYGX to drop everything else and perfect the HVS Rx for the market in India and China. Again, an impt. point or fact will be did either of these gov't give PP the go ahead to clinically used the HSV Rx.The contract/option agreement wording will be crucial to this point.
I do feel as previosly stated that the decision to divert the little money CYGX has to other projects will be as difficult to prove as the context of the LW statement, under question, to PP. If CYGX felt that PP was living up to their necessary end then PP will have serious problems proving much of anything. I personally never thought the CYGX lab would drop all projects for just HSV. I am considering also all the various joint ventures in research that CYGX persues with various parties i.e Baylor University and many more.
Personally being in research, I realized how time is divided in a few to many areas. You got to keep it interesting and alot is accomplished in an eigth to twelve hour day. Alpha Gensis, where I work, presued in just the last few weeks: 3 major research projects - a breeding colony of 5000 primates - and a inspection (which comes every 3 years) by a major organization. Most of this, is par for the course.
On a further note........I do find the board posts of "PP" the poster (trying to help us) as well as the "PP website designer", etc rather interesting as to the professionalism and so on of PP. Someone with a stronge position would not eveen think, much do, this. And some of the coments maybe used in this case, although it would problably have limited if any use, and merely complicate matters.
When the joint venture event started with PP/CYGX, many of us naturally tried to investigate who David Lane was and the parties in PP. We hit somewhat of a floodgate of suspects but it did look like it was a well funded and a smart group of well meaning investors. The name behind PP denotes idealism and spiritual well being. I think I was very wrong with this conclusion ! It won't be the first nor last time.
The "face of God" is frowning on the parties involved.
Any idealism has evaporated in this "good" project gone bad.
Still thinking - Rick
Holycow mentioned the political changes in India over this year and they are significant. I guess it becomes a factor, where Phanuel Pursuits was in dealing with this new government and the ability to be licensed to carrying on clinical studies with a new drug in HSV. There would not be much of a case by PP to CYGX if PP was not complely capable of dealing with the gov't of India. This remains an unknown in this case. I wouldn't be surprised if PP was abit behind in this issue. This could make PP's action some what mute vs CYGX, if PP could not get the HSV Rx to the Indian subjects of the study. India has an open market for new Rx's but nothing is automatic. It was mentioned by CYGX that PP was not set up for handling certain issues we presently know little about. The underfunding of PP does sound strange ? I didn't envision PP as an underfunded type entity (consider the PP players) and why would CYGX get in bed with someone of no-means (?).
Just a possible issue, which I hope the attorney's entertain in the response from CYGX.
Meanwhile India now has the world's worst rate of HIV and HSV and is very aware of the relationship of the two and would jump at the opportunity of a opportunity to control HSV.
Thanks Arnold and Hogger for your fine work. Your posts-work-remarks help us all and for that matter help CYGX (all things considered). The CYGX/IHUB board is truely unique - a story in itself !
Best to all for this wonderful weekend !
Rick
John (Hanuman)..........good post John and extremely impt.
for all humans (even animals) and right, CYGX.
Vioxx is more than a disastor but one must do extensive research to come to even a semi-conclusion. The British medical article as well as other articles, where it stated a low but significant increase in problems (heart and brain wise) were basically causing the individual litigation against Merck to be successful - Merck has been losing everytime and basically settling each case (under the rug) and now it sets massive class-action suits against Merck which will simply bankrupt what was a great phram. company at one time. The attorneys will win, made loads of money and the rest..........?
MERCK IS TOAST
Now the current news on Bextra and next Celebrex, doesn't look good. Frankly I personally found Vioxx far more effective and Celebrex rather poor. We spoke of this before.
I hope the truth comes out on just what happen with these drugs. One point which has come only in pasting, is the pathology to the intima or linings of these vessels concerned. It varies so much from individual to another that major studies, not released yet, may show light on this problem. It also sheds light on some positive aspects to help this vessel lining.
Strange that "baby aspirin" can help so much!
The real problem will be the hiding of evidence by a gaint phram. co., that this drug induced pathology was well know before the drug was released on the market. Frankly I wish it wouldn't happen in a way but the chips must fall.
Meanwhile it is a multi-billion market each year which will totally be unfeed soon. A replacement which could actually come from CYGX would be large.
It's ashame that CYGX had problems with AGI who were pursuing the animal market which in itself is large. It's my understanding, that this too was a matter of incompatible personalities. Perhaps it is more complicated. It usually is that way.
Meanwhile there is a growing vacuum (if that is possible?) in an established market worth 10 billion plus per year With imagination, a new product with the rumored action such as the CYGX product, the market for a safe anti-inflammation medication could a 100 billion a year.
Perhaps CYGX could start such a medication topically and them progressed to a systemeic level. CYGX needs something to get to a postion were two projects canbe studied at one time. Jumping from one product to another doesnt make sense but given their present position, CYGX must proceed this way. The veterinary entry for this market/product seem to make sense.
Therefore your post opens our minds to yet one more possible area where CYGX could help themselves as well as all living beings.
Best John - Rick
Paulness..........normally I would not respond but I'll try.
I do believe in the "tooth fairy" and I knew several on a first name basis - they gave me quarters when I was a kid for teeth, rotten or not but that was a long time ago.
Enough said.
Regarding "Shaunfink" (what a handle?) Its not impt what I believe but history is impt.. If you review some past emails/posts on CYGX/IHUB about a year ago, I distinctly remember a poster stating that were in contact with an individual who was the web-designer for PP (David Lane) and as I remember he did not have much information for this poster from the CYGX/IHUB site. Apparently his telephone number was at the progressiving but not finished web site. I can't give anymore details - it's just not impt..
As I stated , Shaunfink did know and posted yesterday a remarkable number of details about CYGX and I did post to him....."Thou protests too much" (get it?) - he aroused my curiosity in what was making him post to us at this time - perhaps the CYGX/IHUB poster was calling him again or perhaps he is a top-level spy slipping negative waves to upset us all. But it's just not impt. (I think?).
Frankly I don't give a damn! Nor should you waste you fine mind on this detail but do keep posting. Every post and view is impt.
I would suggest to you and all, that "hogger" states not only the truth but has a grand background, perhaps the best on this board, on CYGX and all the principals involved. He is long the stock and not only has a complete understanding of the CYGX science but remains long on CYGX because of the science, as I and you do. I would not look a gift horse in the mouth. There are more than enough "bad guys" out there but hogger will only help you and I do know him. He probably checked "shaun fink" out by the telephone of someone involved. It really dosen't matter - just believe him and go with th flow.
When HOGGER posts - please listen closely
PP (the poster) is correct in his last post....... "court records are public record". Often attorneys and judges are the last to review these records.
Don't you (and everyone) find it interesting how close "PP" the poster, follows these issues and I believe he is not invested.
hogger..........once again THANKS ! - great work.
I agree about the confusion (it's close to a "brain freeze") but often the main purpose of lawsuits is for total confusion of attorney's, judge's, jury' involved using it as a ploy to get something else - they know they can't get 500 mil from CYGX.
There numerous reasons of which some on the board have speculated on.
-To extend an option or get money or just in on the action - The "hanger-on-type". This can only be paid in shares in this case, we know that.
-or perhaps the unthinkable - just plain stupid people involved in this case (cases). LW can lose his cool but could he make such an insulting and damning statement (I don't want to speculate on this possible quote by LW).
-There would have to be stronge evidence in this case as you have pointed out i.e. tape recording on a phone if legal in Texas for evidence as I believe it is legal in New York (one way permission to record on the phone) or by a witness(es) in the room.
-Agreed, why didn't CYGX do complete DD on PP? Is CGYX so impressed with names, that they will jump into deals (or whatever) without examining what the partner(s) in business can really do. Its not that difficult to do.
-Yes, why hasn't CYGX disclosed much more information regarding where the clinical research on HVS has progressed to date. Back to that chronic communication problem. And please all, remember that the statements on HSV what were to be given out in 30 days over a year ago, never were revealed and CYGX lost the exposive PPS advancement it was making upward (look at a chart and news releases from CYGX at that time). This is just a plain fact!
-and so on - most posts have stated the options and I do begin to feel it's a waste of time guessing at the possibles. But we should speculate. Confessed?
Basically, I'm not impressed with the case as it has presented to date - perhaps there is more to come?
I don't think the courts will be impressed, unless there is some HARD and damning evidence to come.
Lets not condemn anyone one posting other than "I don't agree and please state why - the person you are condemning may have one of those "possibles" that just be correct or close to it. i.e ARNOLD once condemned by a few and now......no need to go further.........excellent!
This poor guy who designed the PP web site was being telephone to some degree by shareholders/posters and this was stated sometime ago, by their own admission.
The web-designers "last" post (hope it is) did release alot of detailed information but I sure he could have gotten the details by the callers. Perhaps he was interested in CYGX from the positive reviews of the callers?
Someone regested going to a shareholders meeting and doing a face to face with management - that seldom works out - its a good idea but perhaps you could do it.
Again management does read the board - but if one were to confront them with this fact, they (CYGX) would protest strongely with great tones of negatives and put-downs. You could be told, that the way a company like CYGX will succeed, is to paid for advertisements such as we have been exposed too. Kind of "tacky" but I could be wrong.
Maybe the ligitation will expose CYGX to the world(?).
Wait a minute, I thought this was a bio-tech company!
Nevertheless, CYGX must get their act together soon and begin to communicate with the real world if they hope to be successful. The science is great but it must be presented to the "real-world".
Now that I am more confused than when I started reading the posts, I must retired with a major "brain freeze". Maybe things will flaw out tommorrow. Yes, thats it, I'll think about it tomrrow.
Thanks Ellen for the always nice hello and again, thanks hogger for the excellent road-work and even better questions.
Rick
shaunfink............Me thinks you protest too much !
Hogger.........thanks for the cygx email-posts and your kindness and especially a thanks for all that footwork today.
It's so good to read any post from you - I always know it will be rewarding.
It will be interesting to get to the bottom of all of this stuff.
Right now, it's the blind leading the.............
But remember.........."in the land of the blind the the one-eyed man is king."
Where do I come up with this stuff?
Perhaps I have caught one of those deadly diseases from the primates (?)
Speaking of primates, there are always a few with a chronic illness - a disease referred to as "CHRONIC WASTING DISEASE", - you see a variation of it in wild goats - deer - bison - sheep and other wild beasts.
I now have a new theory that it is akind to the cardiomyopathy's we see so often in cats. Namely a wasting disoder of the cat's heart from a deficieny of TAURINE (amino acid - a protein) which is essential in cats and is now supplemented in all "good" cat foods. Cats response impressively to a supplement of this amino acid (one can get it in a health food store)
I was doing an autopsy a few days ago, on a Rhesus with this problem and as I studied the heart, it struck me how similiar the anatomy was to a cat with this problem. I'm hitting up NAID for a small grant for the expenses on this (got the writers going as we talk) and will let you know what the outcome is (when I telephone you after football season). It could be an amino acid deficency which therefore would be treatable. As it stands now the treatment available - is like pissing in their ear!
Interesting stuff that could go a long way to help alot of wild animals, pets and these primates, etc.
Meanwhile back to the problem at hand. Only time will tell plus, more impt, your detective work at home base.
For my friends on the CYGX board, please hang in there, this hasn't changed the science of CYGX and is another unpleasant hurrle that CYGX MUST learn from (I hope!).
We all have been "kept in less than zero dark" (there's another one!?) about the dealings with CYGX and Phanuel Pursuits and after all this time, there where no dealings happening. Well maybe a few unpleasant ones.
Lets hope that Ocampo is still active in CYGX and can instill some good business sense in this management. As opposed to throwing his hands in the air and walking away - unable to deal with the cleverness of present management.
I am not impressed with the fact that CYGX has all these lawyers or that PP has dozens of lawyers - often that canbe the down fall. Imagine being a fly on the wall of a room filled with dozens of attorneys. WHAT A HORRIBLE EXPERIENCE - talk about cruel and unusual punishment.
*Remember what Bill S. said "first we murder the attorney's" - actually that statement in the Merchant of Venice was taken abit out of context, a expained to me by an attorney friend of mine.
Well Jerry, did you think I have accomplished anything with this?
Take care HOGGER and all - RICK
skooby...........I agree the lawsuit by Phanuel Pursuits is probably "sour grapes" - I just wish we were being informed more about it and did not have to find out about it from the "PP" poster (who I believe is directly involved with Phanuel Pursuits).
I also understand why CYGX cannot disclose information on an active litigation. Having said that, a release from CYGX given in a professional and informative manner to us, the shareholders, would be logical, helpful and legal.
Communication has been a horrible short-coming of CYGX.
The decisions behind a few news posts, released in past, have sometimes been mistakes i.e. the famous HVS mouse experiment carrot to be release in 30 days - over a year ago (I see that event as an impt. turning point in the trading of CYGX). Many of the releases from CYGX which are extremely impt. are somewhat lost among other releases which are almost but not quite fuff - this usually happens.
CYGX is a small developing bio-tech company which someday will grow into the great bio-tech company we all envision. When a developing company is in this stage, mistakes are made because there are so few to oversee the mistakes of the few others i.e. Berlin stock market listing - regarded by CYGX as a great plus and now possibly a disastor waiting to happen (?) - CYGX should examine this matter and get out of Berlin as other companies have done, if the stories are even remotely true regarding this market. Makes sense to me.
Making mistakes - we all do it - is normal but discovering our mistakes, recognizing them and doing something to correct them canbe the difference of success or failure. Anyone can make a mistake but a true and successful leader is needed to correct them and even admit to them.
Having stated this and on a positive note, all corporation of any note are involved in litigations - what is impt is how they handle it now and negotiating future partnerships.
As I have stated many times before, if CYGX is only successful in one of the many areas of investigation i.e.
sepsis - HVS - neoplasia - anti-inflammation - and so much more, the PPS will be a pleasure to watch.
I may have misgivings about management but I will always state that they have given all they are capable of - further growth and developement is mandatory in any venture such as CYGX especially in the management area and they must be aware of this fact.
I guess we can all agree that CYGX basically has been moving forward in a difficult area. Perhaps it is abit slow at times but that is the nature of the beast.
A massive improvement in PR/communications is needed on a professional and common sense level. Can't we all agree on this point?
However, we, as intelligent and informed and loyal shareholders, have a duty to keep management on their toes. Remember they do read this board and this is good.
Lets try to put these law suits on the nessecary attention level due them and nothing more and look to the present Pre-IND event at hand with postive minds.
IND's are impt ! and I feel that the present legal actions while not desired canbe learning points for the management at CYGX.
OUR TIME IS COMING (or near, depending on one's perception of time).
***Check out "inter_Pares" post #857 (Ihub/CYGX) on 8/25/2003..................... To amplify the excellent post by Thaliomiles.................................it's a keeper, explains alot and is in my folder of helpful posts.
Best to all - Rick
PS: please forgive my posts for errors - my original iMAC has seen its better days and will be replaced shortly.
arnold............sorry on the confusion with the PP (the company not the poster)
I get the feeling from what has transpired that the company - Phaunel Pursuits is the problem in this CYGX - HVS - PP deal and Phaunel Pursuits has nevertheless started a legal action. Hopefully CYGX can get a summary judgement on this action to dismiss the case.
I say this by putting together what has transpired (much of which we don't know at present) and what is logical. The dollar amount of any legal action has no meaning and words are thrown about without regard for the meaning.
Yes FRAUD is serious! and I can't really envision this.
The Fraud term is alarming and therefore the reason it is used. The real failure of our courts is to permit suits without merit to have a short day in the sun. But it would be a failure too, to not permit every dog, it's day in court. To roar with high dollar amounts and free throws of words of any type without much regard for the truth - truth often is the last thing sought after.
Breach of Contract sounds not only better but a little more accurate if there is any merit to the action of PP vs CYGX. Using false words and false actions will often get a case thrown out of a court.
PP, the poster, I feel is someone connected to PP, the company and this is where I find an unprofessional move by PP the company and poster. Remember how much and how hard he tried to help us see the light. Perhaps the postings will move into a court action - probably not.
Boy ! It does get complicated but that is often the desired and intented effect.
I do believe this will all past with time. I do hope it has not been some underhanded move by all parties to manipulate the PPS. This would be very bad, so lets not even consider it now that I have questioned it.
On thing is for sure - it is complicated especially without knowing all the facts.
The mice in the HVS experiment are dead from OLD AGE and we still do not know the results. It should NOT have been presented by CYGX with the - 30 day results - carrot. That was very foolish and did cause a severe turnaround effect on the PPS. Good forward movement was losted even to this present time. Alot valuable posters on this thread gracefully bowed out thereafter. You know some of them and they are missed.
The research article will no doubt be published after the research is finished, paper written, peer review done and publication date set............................30 days ???.........big mistake!
Thanks for your comments otherwise and please keep up the excellent posts.
Rick
arnold.........very interesting post, to say the least.
I must compliment one and all on most of the posts over the months (meaning summer-fall 2004). It is truely an outstanding board.
I have been very busy over this year and while I have read the posts, I have remained silent because there wasn't much to say. Just an occasional joke!
As "hogger" stated to one and all that I actually feel somewhat charmed to be here, since I had a severe "spesis" last November 2003. While I lived, it gave me an endocarditis which in turn has lead to a arotic value failure and much more. I believe it canbe dealt with but this is what "spesis" is all about. VERY serious stuff and any cure in the future more than needs our support i.e. CYGX.
I do remain faithful to the science of CYGX which was not created by any of the management presently. It was discovered by several sciencists of which I believe only one remains directly at CYGX. The history of CYGX is tortorous and strange!
This is not that impt. But it may shed light on who we have today.
Our present management weather you like it or not, have failed CYGX is a miserable fashion. I can only hope that the science of CYGX can find the light of 21st century medicine and set the management free.
My personal experience with management has been down right embrassing.
My one and only conversation with our PR man, left me with a number of "I don't know and I will find out and get back to you". He never got back and frankly that was just fine with me. It was an embrassing conversation with Juan, wanting to know what I thought about "thalio" (over and over again?) and a complete waste. He is simply in something over his head (sorry Juan).
I have picked up from all of you about the same. One does get what they paid for. I can accept that.
Our CFO - we have had maybe 2 or 3 conversations over 5-6 years. He is a screamer, as in, if he doesn't get his way or is not in control of the situation - he resorts to screaming. Real class and this does distrub me. Prehaps he was having a bad day?
I know for a fact that the CEO needs the CFO to the degree where he retains what canbe only described as an embrassment. I really can't say much more for the CEO - which after 5-6 years is rather bad. But I do believe he needs better help.
CYGX has brillant science with ridiculous management.<b/>
Accept this fact, I have and I sleep a little better for it.
Thats just how it stands today, 5-6 years of watching one mess after another. If you disagreed, thats fine, but how can you explain the actions, inactions, failures and dragging for all this time. This stuff is just too impt. to mess up!
For example - the ligations - 2 currently - both resembling each other..........but lets give them the benefit of the doubt.
Frankly the PP problem sounds somewhat like "PP is the primary problem (see the previous post by arnold - this husband and wife team do their DD work to an impressive degree - we must all learn from each other weather you agree or not - you can learn). Time will tell on this.
One thing is for sure - the street knew about this event for sometime and YES - the posts by the mystery PP poster show truely - DESPERATION and were rather unprofessional......................... I wonder who PP is?
Speaking of mystery posters - who is PARES - 2 posts in 2 years and both very significant.
First one................ to enhanced a science explanation by THALIO - which was quite excellent (no neophyte wrote that post - right out of some area of the company).
And the second post - read it, it does answer our present problem with management - who else are we going to get right now? I don't know????
The second litigation offers more of an insight to CYGX doing business (or not being able to do business) with someone else.
Forget any business in veterinary medicine for the time being. Its in the courts and it won't be over till the arm-wrestling contest is over - meanwhile more time and business wasted.
Consider when CYGX in the future negotiating with a large business as oppose to these nickle and dime operations. What will happen? The present CYGX approaches are poor and apparently do not work.
I remember when the statement was made by CYGX, that results in HVS (and mice) would be coming out in 30 days. This written and released by the company. And CYGX began to fall apart. I can remember speaking to the CFO about this and getting these strange high pitched noises saying something about.....if you don't like the way I'm running CYGX, them sell your stock. Alot of people did...........I didn't !
Whenever an officer of a corporation makes this type of statement of desparation - its time for him/her to leave.
These are just random thoughts. Some may not like them but they are facts.
I don't think for one moment that ss-DNAscience/medicine will fail but I do question how the present management will solve the problems they have (therefore we have). After all it is a public company - we all own some degree of it - this is point losted by CYGX's present management. WE ARE OWNERS AND INVESTORS OF CYGX<b/>
Gut feeling..............CYGX could find success with even the negatives at work, it just maybe abit dangerous to do it this way - and after all, where could we find someone better, to run CYGX at this point?
Thats it for now........Skooby, you have my total permission to attack me now but whatever you think, I do believe
our time is near<b/>
Best to all.........keep thinking & posting. And please don't give up!!!!!!!
Rick
Just wanted to add.......................
99% of attorneys give a bad name to all the other
Suky.......regarding Applied Veterinary Genomics......weather its filed in courts, I don't know, but there have been numerous statements of same.
Whats really sad, the entire veterinary area with so many applications and possibilities is totally wasted because the parties concerned cannot get along.
Sound familiar!
"Ship-High-In-Transit"
Those who do not learn from history are condemned
to relive it.
Don't you wish we could just meet after school and
duke it out.
Perhaps "Hogger" could offer some light on the present status.
Those who do not learn from history are condemn to re-live it !
The 16 - 17th century --- everything is transported by ship.
It was also before commercial fertilizer had been invented,
so large shipments of manure were common. It was shipped dry for then it weighed far less but once at sea, with water hitting it in lower holds, it became wet - heavy - and the process of fermentation began again - of which a by-product was methane gas.
The stuff stored below decks, you could see what would happen. Methane began to build up below decks and the first time someone came below at night with a lantern -
BOOOOM !
Several ships were destroyed in this manner before it was determined just what was happening. (learning from history)
After that, the bundles of manure were always stamped with the term, .....................Ship High In Transit...............on them.
Which meant for sailors to stow it high enough off the lower decks so that any water that came into the hold would not touch this volatile cargo and start the production of methane.
Thus evolved the term S.H.I.T.
which has come down through the centuries and is used this very day.
And I always thought it was a "golf" term.
We do learn from history - only forgetting it once in a while.
Best to the marvelous posters of CYGX.
Rick
suky.......printed the material you research for us (thanks).
Briefly looking at it, it is interesting that Yang Shi early work dates back to March 2000 - the research for that paper would go back to 1997-98 and the work itself, possibly to mid 90's. Also noted references to RNAi, which we know now has had numerous problems - thus I am wondering that perhaps the CYGX ssDNA vector has shown promise of late (meaning over the period of 2000-2004) and has been furthering the research in this area.
It must be noted that CYGX has been sharing "vector ssDNA kits" with numerous parties interested and that very little has been disclosed about this.
I remember on numerous occasions CYGX parties talking about a large amount of interest in the ssDNA vector kits and how there was so much interest - CYGX had to discipline themselves to concentrate on the issues at hand such as HSV, spesis and some neoplasia areas
Again, I feel it was not an accident that MS comments were sought after and given. I believe this could be very impt. for CYGX and would certainly recieve attention at all levels.
The science community behaves in strange ways at times and often when an area of impt. opens up, there canbe quite abit of covert play. In the 50's, the DOUBLE HELIX was published (Waston and Click) which got into just how this community can work.
I wonder what caused the UPI story to materialize. I would think it was a recent paper (summer 2004) by Yang Shi and/or paper presentation or both. I believe we can anticipant more releases concerning this work and it will be very interesting in discovering CYGX exact role in this area.
Rick
Paulness......CYGX ssDNA vector could be involved in a means of the delivering the silencing mechanism of controling the developement (or undeveloping as the case maybe). The CYGX ssDNA vector has numerous possibilities that canbe expanded beyond the areas we have been informed to date. This could shed light on why MS was asked to comment on this area of research.
This is why the CYGX patent is so remarkeble - its possible uses are very wide.
I believe we are being given an impt clue by MS's comments as to a possible new venture for the CYGX patent.
CYGX'ers.........the RAINBOW MEDICINE COMPANY (one more light shines bright for the future)
Please re-read the article posted by "suky" and "taton" regarding the Harvard research and especially the quotes by our CEO - MS. This does show an important and completely new direction for CYGX and is surprising but when you think about, it does fit in nicely in the area.
This is a very important move by research to "back door" the means of STEM CELLS production and therefore further needed stem cell research. While the world is mostly free to harvest stem cells the US has boxed themselves into ethical questions which may never be answered. We need "stem cells" research to progress medicine and find clues for dozens - perhaps hundreds of pathologies plaguing humans.
Consider the ramifications of the ecomonics in medicine... .......i.e. to not treat but cure completely heart disease with totally normal quality of life with in reality a simple proceedure - to grow spinals cords - to create a pancreas producing insulin - the bounds have no limits and it may answer the mounting problems of medicine (the one of compassion strained and ecomonics out of hand).
If CYGX is headed into an area of "back-dooring" production of stems cells - it would answer so many questions and problems and eventurally advance mankind into the 21st century. Any company within this area would recieve much deserved attention worldwide.
This is an exciting find and once again thank you "suky" and "taton" - excellent work!
Best to all - Rick
suky..........MS comments (to Harvard) put him in the proper circles which are impressive.
Generally speaking:
I do get the feeling that there is quite abit going on in a postive light and that the NA's are being compiled to be released in an orderly manner. Frankly, at these present manipulated prices, I would not want a NA released. It could be an utter waste of good news.
For example, the approval on the HSV Indian project by Phanuel Pursuits has been possibly backed up (in a extremely minor way) by the fact Indian has a new gov't but this new gov't is very pro HIV control and Rx and is aware of the relationship of HSV and HIV. Thus CYGX's attack of treatment/cure on HSV will be looked on in a interested and favorable light.
Look, in the early fall, for events to take place including some clue to finances.
Look to the present for stock accumulation at obscenely low prices. If the price falls further, so be it and pick up some more. I know I will be doing so.
As I have said, nothing has changed with CYGX fundamentally and in fact much continues to progress.
Science and medicine dose not happen in months or even in a few years - CYGX (and the ssDNA vector patent)
has been researched for approx. 7 years now (perhaps more). Considering the nature of the pathology that CYGX is involved in, FDA proceedure could move forward in a fast-track manner. Time will tell but the "spesis" problem is monsterous. Medicine does not have the luxury of time with this problem. We need answers for the next year (2005). The FDA is well aware of this and will accomodate new medical technologies as permitted.
Look to our glass as half full (not half empty!).
Yes CYGX canbe frustrating regarding management and communications to investors but there are reasons for this which I accept (I more or less have too). The management parties involved have not invested 5-7 years at low salaries at best to fail now.
We have all investigated the science of CYGX for over 5 years and still believe it could be the major performer in medicine of the 21st century. Where can one invest both for a money return and your personal health safety.
Don't be bummed-out by bashers and/or psyhcopaths. You know who they are and they are not worth the time to read their oral vomitus.
Take the time to educate yourself, as I try to, by reading and considering the constant supply of information from "suky" and "taton" and all others who give of themselves to help all here.
CYGX board - have a great weekend and hang tough!
Rick
Today is a classic sqeeze by mm's to horror the shareholders and bring down the PPS to take out stop loss orders and pick up shares to cover a large position of shorts. The mm's are totally unaware of what CYGX does and are playing the numbers only. This does not indicate that news is nessecarily coming and if it comes, it is not connected.
The "signal" this AM of a small block trading (i.e. 300 shares) is sent out by a mm to orchesrate this entire performance. They send bashers first - which set up a mood of aniexty - then swring the trap where many weak hands suffer............it should be illegal and will be someday.
STAY STRONGE!!! NOTHING HAS CHANGED.
Rick
"investigating the Berlin sitiation"........let's hope CYGX has an insight and removes our corporation from a potentially dangerous postion.
If CYGX does not trade on the Berlin Exchange as noted in the lack of volume, then in light of the definite dangers of having a stock listed in Berlin, why remain in this precarious situation?
This is NO RUMOR! Stocks get shorted in a naked manner on the Berlin Stock Exchange and I do beleive that CYGX has been shorted from time to time over the past year. I also wouldn't be surprised if quite large portion of CYGX naked shorted position has been covered and more trips to the well are perfomed daily. Thus while the Market Makers have made money - we have lost money and CYGX suffers the results and why(?) - has it helped CYGX.
Financing a BioTech is difficult enough but to have this poor trade record makes matters worst. Great science only goes so far. It may make me an investor for the sake of the science but many look to all factors - science and management. To ignor this danger of a Berlin Exchange listings may give potentials investors the wrong picture of our BioTech co.
Thanks John for your emails to management. Wish we could just be concerned with the science and further animal studies.
CYGX Berlin Stock listing?............has anyone found anything about this listing and the connection to "Naked Short Trading"?
I still have stronge feelings that CYGX maybe in dangerous exposure with this listing in Berlin and is there any justification to have this situation.
There was an attempt by CYGX to explore trading and financing in Germany, thus the listing had potential value at that time, but that is in the past and appears to be unsuccessful.
If a listing on Berlin exposes the corporation to "Naked Shorting" - why do we remain in this position?
Opinions needed - TIA
CYGX board........texaslongtrader is an asset to the CYGX site.
There maybe a connection to another poster but it is not "TLT".
LO past posts if you read "as quoted" are actually a positive to the future of CYGX. If you are influence by LO then I fear you will get
what you do not deserve. All this nonsense has turned off many valuable posters.
Meanwhile thanks "suky" and others for these continuous and very valuable posts. It's really appreciated.
I believe we will be, unfortunately, seeing many cases of sepsis in the news and many of these will be about litigation in sepsis cases, where everyone (save the attorney's) losses. Sepsis has many variables and canbe difficult to prove where the true responsibility lies.
It could in time put hospitals out of business. Something must be soon - we do need places to heal in = hospitals.
Have a great weekend all and keep the faith.
Rick
Paulness.......not bad thinking and you maybe right on target!
There is a plan after all these years of work and considerable advancement.
Something this large and of this importance takes time and more to mature. And of course some luck to happen.
My thoughts...........keep informed and educated and be patient.
neo43........the post on the "breaking of the genetic code of
MRSA" is really impt for CYGX. Namely this gives the genetic means of CYGX using their tech for a defensive move which would be met with the open arms of a grateful world and I might add a more than grateful medical community - which is running scare with this problem.
John - tried answering the email you sent with some problems - will try again. RICK
skooby........you bring up an interesting point that I can't help but to consider - remember the early posts - what came first first and why - who is who, know what I mean?
CYGX "The Future" - 99% of the posters on this board have done advanced research on this croporation (probably more research than any other company they have invested - I know I have). The science is very impt but when you look at the participants in CYGX ................!!!
Thats why I doubled up last summer 2003 and have given the rare buy signal to friends (after they do DD).
The board, both the BOD and the Science Advisory Board, are a who's who's in this field and this must give confidence to all involved. Why would they be involved?
There have been some valid points about CYGX management, this is why I was very happy when new board members joined us, These are growings pains in developement, especially when consider the way CYGX has developed with very little cash.
The "delivery system" has never been an issue and until that issue is brought up with something quite definite and from a "respectable source",
I will worry about "global warming" but NOT the CYGX "delivery system". So far it has proven itself.
suky.........Hunt involved with Phanuel? Good point!
NERVOUS FROM THE SERVICE
Please to all who are being influenced by LO, think about what you are doing.
The posts by LO are tinted with a bitter investor who has a
self appointed mission to create an atmosphere of negativity and doubt. WHY?
Is he being paid - I think not.
Is he trying to drive the pps down - that is happening but I doubt at this point he is responsible for that.
Is he personally mad at CYGX - perhaps, that how I see his posts.
Does what he posts make sense - no.
Frankly I don't know what his game is, but it definitely is NOT to help us think about CYGX.
Basically he creates an air of frustration even if you don't believe in what he posts.
Attacking other fellow CYGX posters is a poor way of selling a view on CYGX. It tells more about him than what CYGX is doing. He is obiviously known in the "Texas Group". And this fact, makes me think its a "sour grapes syndrone".
Meanwhile he is influencing a few investors now. This where I get abit anger with his petulance. Because now he is hurting directly some who are buying the atmoshpere he tries to sell.
Don't buy into someone like this. It's all a distortion to cause nothing but harm.
This investment is a gamble at present and until it receives
fiancial support and gets into the IND phases of studies it remains a gamble. But we all know the facts and details and as time goes on, it always looks better.
I believe CYGX has always had a minor problem with communication but the science still makes sense and remains outstanding. Remeber CYGX is a small company with limited employees - all doing double duty. The possible end products are more than great, thus worth the gamble we take. This what investing is all about and now we have a chance to invest a relatively small amount with a great return on a good and useful product. This is quite rare.
Finally the corporation should not and certainly would not respond to the pandering of an LO.
A post-note: Thalio has a very busy life and still remains informed of CYGX - I dare say he will return as the action develops. Looks like the second half of 2004 thur 2005 will be an interesting one and half years for CYGX and the "daring investors" in same.
suky.........appears to be back up (CYGX website) 11:00am EST.
CYGX shareholders meeting - will anyone be going to this meeting? If you are going to the meeting, would you consider posing the question regarding the "non-functional" listing on the Berlin exchange and why we are listed considering the dangers of "naked-shorting" by MM's when a stock is listed there. Please let us know.
There are no benefits, I see, in being listed in Germany at present and real and grave dangers.
Please read the articles regarding the "naked-shorting" trading which is out of control and is creating a threat to the entire world markets. Suky has listed a number of these.
Paulness.......excellent post (very wise).
Shorting Stocks (Naked Shorting as in Berlin)
Has anyone ever gotten a solid answer on this issue?
It seems to me, when you consider we ready don't trade on the Berlin Stock Exchange but are listed there, we are at the very least exposing CYGX to naked shorting.
I believe after following CYGX for 5 years that the stock has been shorted in a naked manner in the past year. This would explain many things regarding PPS. At least a little of it.
The common sense move here would be get out of a dangerous situation especially considering the lack of good it does - namely GET OFF THE BERLIN STOCK EXCHANGE at least until it could do some good instead of just bad exposure. Lets not wait till there is an exposure on Dateline or 60 Minutes.
I wonder if we delisted a stock which is not even trade on this exchange if there would be a stampede to cover shorts - I don't know - it's not my area. Do the shorts exist?
By the way - who is this "LO"?
Looks like he's starting to really hurt some other investors - Of course anyone who would puts any creedence into his babblings may deserve same.
Please all, listen to what makes sense, as in common sense - we have an excellent gamble here in something really good - not all good things make it but some do and they often are the BIG ones - lets not blow it at this point - this is why some of us have been there for 5 years plus. And I must add, many of these people here are very impressive.
JSIMON1018........excellent post!!
archinla......correct, the PBS show (believe it was a Nova) demonstrated a clinical case in Germany(?) where a rather young patient (35-45) had fairly severe left ventricle pathology where the individual "ejection rate" (cardiac output rate from left ventricle -normally 50) was headed towards conjested heart failure. After the proceedure, there was complete success, as demonstrated by a side by side comparison of a before and after echocardiogram. It was more than impressive! it is exciting for medicine.
The success is outstanding but just as impressive is the simpicity of the proceedure.
There is one complication - to shut off the blood flow to the ventricle in a diseased heart could throw the heart into a posible lethal heart beat. This is monitored closely during the 20 minute plus angioplasty proceedure. Therefore time is a critical factor here, thus we need a means of a faster delivery. A delivery of stem cells into the mycocardium in say 5 minutes or less.
There is another similiar proceedure where thur small chest openings injections are made directly into the heart muscle. I see limitations here such as an critical invasive proceedure and somewhat hit or miss or a poor means of delivery.
This is all great stuff!
Hoping for a NOVA program on SEPSIS - I know nothing about this but it certainly makes sense and the need to educate the public is obivious now. This, if it is happens, must include CYGX - lets hope it does.
We still have that mystery of the "other film crew" at CYGX offices - passed off now as a future promotion film(?) - for the future in the distant past -
perhaps but I can dream on.
Stem Cell Research and (hopefully) Treatment........getting alot of television news coverage which will filter down to written press.
While this has nothing to do with CYGX - it does in a around about manner. And it all comes up now once again because of the lost of our 40th president. Even in death he helps us.
I hope we can wake up legally and morally to this needed area of medicine - I think we will.
The advances in not just treatment but CURES are amazing.
Just the studies in heart disease, which are actually being performed in Europe, are so advanced yet so simple and ready to performed worldwide. Doctors can harvest stem cells from the individual (bone marrow of the ilium) with heart pathology (a lack of vascularization to the myocardium - coronaries arteries and more impt arterioles to heart muscle) and develope these cells which will be put back into the individual with heart pathology and with a simple angioplasty (the balloon proceedure in the coronary vessel)
held in place for a short peroid of time (10-20 minutes) in the coronary vessel where the harvested stem cells are absorbed into the myocardium tissue (actually heart muscle which we now know can regenerate in many cases up to 100%)............................................................................
AH!!! this brings up something else now - "DELIVERY". Could it be that this proceedure maybe done far better with a "ssDNA" delivery system in an indirect "end run" way. Unknown now - maybe it hasn't been considered but this what I meant about the relaionship of CYGX with "stem cells". It's very indirect but any advances in the permission by the government into genetic research and uses in medicine will all genetic research.
If the public becomes better informed about the entire area, we may get the "road blocks" that inhibit this area of research. It's a difficult situation peppered with total ignorance and endless moral crusades.
Meanwhile Europe is far advanced to the USA in this area - which is find but we (USA) could be a large help in this research of future medicine.
Hoping for the very best - Rick
khw22.......For more information on Dr. Joesph Demichael great website, go to the "googled" (the verb) page that suky found and just work backwards though it and its various subsites. Nice website.
I bet you have already done this.
Have a good friend (Dr Trochet) in Beaufort (my south home base) SC who did world class breeding (AI) work for Hunt with Dr. Demichael. Its all quite interesting.
As to the Doctors status with CYGX - don't know right now.
But it would surprise me if he wasn't a part of the shareholder's list. We would all be surprised as to the real shareholders list. But it's medical science that counts!
Best to all - Rick
Nigel........you have a valid point regarding many of the press releases of CYGX which are often vague. Frankly, it's a press-relation nightmare and some at the company have not wanted to face these issues. But the science is so impt., I will put up with it - it will only get better.
My feelings are, I'm in it for some brillant science medically which I hope will make it to the light of medicine in general.
This is always a gamble, no matter what your product.
Note to all of us: the IHUB CYGX board is BRILLANT but.....
I am a bit amazed at some of the statements made from time to time especially when we are frustrated.
Again to all, please review some of comments made by "Hogger". He has been in this science and business from the beginning. He does know what he's talking about - he states the facts.
Foget about this "LO" - ignore him (give yourselves a break) - it's just cannon fudder from a questional source - why subject yourselves to walking into this trash.
Meanwhile, I think this has been an impt week for us. It repairs a large bump in the road.
Maybe it COULD help future fund sources (?) but believe me it HAS help us and CYGX.
Hunt will not sell this stock - he's knows what it could do!
Hemco settled the dispute for 25K because the 10% deal should have not been an issue in the first place. It's now history with NO future bad influences to come. Stop reading nonsense into the facts. Our cups are half-full.
To mention "arnold" with "LO" is rediculous - "arnold" brings up good issues which you may not like to face but are usually excellent. And they have been rather lonely in doing so. Bravo ARNOLDS!!!
Now "LO" - well, give me a break!
Besides he's on ignore and therefore I don't know what he is saying and I am happy.
"I FEELS GOOD"
........and please correctly identify the bashers and insane before shooting!
djharker.....basically everything you say is correct but think about what "hogger" has stated (and he knows).
The possiblity of a pending litigation would a turn off many, if not all, to say the least and 10%!!!!
Thats quite a bite out of a corporation. The structure of the deal had problems and who wants problems.
The science is difficult enough - who needs more possible problems with Hemco.
Besides the logic of it finally being settled should tell all something - like good news!!!
BigB.......Maybe able to alert "chipped2003" on the IHUB Trading Momentum Board" - meanwhile, the ignor button on the CYGX IHUB board really works well.
I am not even aware of this persons presence.
If that doesn't work for us then Tony will help.
This board is simply brillant. But you must listen to all the facts and never forget even one.
"The one eye man is king in the land of the blind"