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i believe seth klarman is a major holder of sygp and true to his LT value oriented process, he stayed til the end.
even famous investors have failures i guess
hahaha wrt to revance i consider retailers to be the modern day equivalent of southern slave owners. they want their $ to work 24/7, worse than the old slavers lol.
$ has to grow day in and day out, no slacking allowed. even as the sucking squid put a PT of 50$, which may take a couple yrs to reach (or less as i believe) modern money slavers have no patience for that.
yes but 6B$ is still a pretty stiff price to pay for something that as of now sure does look like an way overpaid deal.
perhaps this reflects the eagerness that abbvie had for this deal. i can't remember but wasn't this inked about the same time period that celgene was also signing partnership right and left that didn't turn out too well either.
celgene stock has been also cut in half ; it was touted by "analysts" of course as a perfect, ready made, hit the ground running, perfect bolt on acquisition by big pharma.
amazing for me to be still able to spout corporate speak BS 20 yrs after leaving HP under evil queen Fiorina lol
tx, i guess this means tril still qualifies as lotto ticket then lol
is this F6 filed 11/29 ie today a poison pill defense ? it looks like one to me
https://investor.amarincorp.com/static-files/ac1876d0-d6ba-413e-b824-37b8f168b1e9
there are certain biotech values i bet on ,when they go red, i'm not too concerned about like rvnc.
some others , when they bust, i know they are gone without any hope like opht, mnkd for ex
I'll add if rvnc goes below 20, which it might. that's what a value investor like me is supposed to do lol.
as i remember duggan's bets have not been doing well, beside plse another one blew up but i can't remember ticker
about amrn Vascepa i wonder what happened to evidence based medicine ?lol
doesn't EBM mean exactly that ? we measure the results even if we don't understand why ? recently i read a report on how metformin works through the gut microbiome. how long has metformin being used without a mechanism ?
if anything i re-learned again and again is human behavior which i consider a very important part of my speculation process
Big owners like BBs don't or can't sell out their big stake without crashing the price. They only get out through BO which in this case I suspect is their original intent anyway
hahaha why not ? i don't get along with all of my family or my wife and some of my friends I don't really care about too much.
Give them bad advice seems to me a damn good way to get rid of them for good.
weak hands taken out ? i see it happens all the time
oopsie, too many customers or so called investors on margin or leveraged to the eyeball i guess. i am tempted to add at these levels
lol amrn board is a cult lol they have suffered long enough. i don't bother with amrn board myself, very little info to be gathered.
biotwerps antics and so called online cognoscenti opinion regarding V full data aside, i wonder if BO is in the card for amrn.
i've had a BO before when amylin was bought out by Azn and Bmy. personally i think the odds amrn being independent by next yr are rather slim. what do you think ?
you are spot on about personality and ego involvement. AF I've known for yrs ,going back to his thestreet.com days ,is a lightweight in bio knowledge.
While he is no good in data analysis, he is quite useful in bringing into the spotlight the financial and PR shenanigans of cheap price stocks and thus earned himself a (not deserved notoriety imo) among those retailers who love gambling with penny stocks .
As far as Matt Herper, in this case I do have to agree with you. He was sceptical about V top line already and yesterday imo was just digging deep enough to validate his preconceived earlier biases.
In terms of human foibles what these two did yesterday was nothing new to me. I can't remember whose quote is was ,but imo it was quite perceptive about human nature. "Scientific knowledge advances one death at a time".
Just remember how hard and how long it was for radical mastectomy to be dethroned or better yet how difficult for the bacterial diagnosis of ulcers to become mainstream.
thank you for your contribution to this forum btw
Mr Mkt reaction to NK is my personal regular process to calibrate my mr mkt behavior gauge. it helps me not to feel despondent about my rvnc stake etc
not a pleasant experience, just a dose of reality about human behavior. NK volume today will probably reach 100X normal volume.
No, i have a small take of 10Ksh in adxs. i believe adxs to have a legit pipeline and scientific ability. the issue was with its former mgt crew who has been replaced.
it's different with sub dollar biotek values with repeated failures and really no pipeline.
i am down 30% with adxs btw lol
i am leery of penny stocks too like gnca
Dew, what do you think of Amarin's patent on method of use here. Looks rather iffy to me
----
AMRN gets two new R-IT patents
Second one is HUGE - prevention of CVD - also note the patents include DPA, which is probably why Matinas gave up on developing MAT-9001:
Methods of reducing the risk of a cardiovascular event in a subject on statin therapy
What is claimed is:
1. A method of reducing a risk of cardiovascular death and/or unstable angina in a subject on statin therapy, the method comprising administering to the subject 2 g of a pharmaceutical composition comprising eicosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid per day for a period of at least about 2 years, wherein the subject has a fasting baseline triglyceride level of about 135 mg/dL to about 500 mg/dL.
Methods of reducing the risk of a cardiovascular event in a subject on statin therapy
What is claimed is:
1. A method of reducing risk of a cardiovascular event in a subject on statin therapy (a) with residual atherogenic dyslipidemia and clinically evident cardiovascular disease or (b) without clinically evident cardiovascular disease but with increased risk of cardiovascular disease, the method comprising administering to the subject a pharmaceutical composition comprising about 4 g of ethyl icosapentate per day for a period of at least about 2 years, wherein said administration reduces risk of cardiovascular disease, need for coronary revascularization, risk of unstable angina, risk for stroke and/or risk for myocardial infarction.
----
https://www.investorvillage.com/smbd.asp?mb=2294&mn=2674&pt=msg&mid=18233807
North, i stop speculating on tech many yrs ago to concentrate on biotech values lol
btw i was an ibm-er first out school , but i was in with the 1st generation paternalistic ibm. that ibm died when mr nabisco biskit came in in mid 80s. we are talking 2nd gen ibm now , which is even more bullshitty.
the current ibm ceo rometty came in guaranteeing/predicting revenues/profits 5 yrs in advance. i remember that fact very well.
i speculate nowadays strictly based on 2 issues/factors. since we're talking biotech , the first is the value/promise of the pipeline and second the honesty and integrity of the CEO or mgt. I've burned too often by the character of mgt
Dew, this is what selb says about svp-rapamycin
http://selectabio.com/platform/svp-for-immune-tolerance/
i was looking for Selecta Bio SVP-Rapa to mitigate ADA issues but now I am not so sure.
It's AI Dew and AI is eating software and software is eating the world lol.
btw i have noticed Big Blue's descendant (can't tell whether it is his son or grandson ) is failing miserably too when not on TV's Jeopardy.
I know enough about AI by slogging through Pedro Dominguez's "Master Algorithm" (and it was a hard book for me to read ) to know that there is a long way before SkyNet rules the world.
Not until people can teach/write code to make silicon think or reason causally like any 5 yr old child would to solve problems, then i would be afraid of Skynet.
VTVT over the years i have more than noticed mr market "pronounced" predilection for cheap stocks. wonder why ? lol
Kiwi, amarin is literally running on financial fumes imo. my common sense tells me whatever $ they have left on hand is nowhere enough to ramp up their sales once the details are out at AHA, assuming of course they pass the sniff test. Hence something else is cooking lol.
This is where off label Tx will come in handy. I've heard about it a lot in the land of biotech values and for ever too lol
so why hasn't Amarin dilute yet? it has been 1 month. do you have an opinion ?
i'll wait til after financing done and then some . no need to hurry imo
hey JL you misunderstand me man. i ain't no short. i was in amrn in 2012 and was suckered in by that scam artist Joe "more deals than employees" Zarkreski and was killed by Adcom in 2013 , losing more than 500K$ according to Fido.
I could be more exact but it was so painful i'd rather not find out for sure since i moved on since then making all of it back somewhere else.
I bought 25Ksh at 3 on 8/27 and i am hoping to claw back some that $ thanks to the herd rushing into amrn. i have always been sarcastic about the ST momo behavior of retailers.
you may want to ride amrn to the moon, but i am a survivor of dndn, elan and i have learned not to be too greedy. my MO/process is to get in early , bear the risk of the event, and do the sayonara dance when the herd rushes in afterwards in the case of positive outcome.
so GL to you and don't think of me as an enemy because i am not lol
oopsie AMRN losing steam , oh well, live by herding ,perish thru herding
Amrn above 18 mc>5B. herd power lol and tilray>150 while legit co like fgen trades like shinola heh.
from a human behavior pov it's suicide for amrn to engage in any sheenanigan.
RI PR results are in blow out category.why would they want to jeopardize that ? like having a 5X gain or more only to give it all back a few weeks later at AHA ? you gotta be kidding me.
it's their hail mary pass and it is caught so i believe full details will bear out top line PR
amrn above 15 now , never underestimate the power of herding. in this case good because i'm in it and bad like in gern lol
Tril the other presentation is here :
https://s22.q4cdn.com/183592819/files/Discovery-on-Target-28Sep18-FINAL.pdf
Slide 22 is what's new and i guess more details at Ash18
were you here in 2012 ? i was .JT could say something like what Zakrewski said back then which was " i got more deals cooking in the oven than i have employees " and price will go to the moon lol
i got suckered in by that and lost big $. i made back about 30-40% last Mon and still has some way to go to break even
OK tx, i did look up CSO filings and you are right
yeah but isn't aurinia LN trial readout due in 4q19 ? a long way to go to get excited early ?
Anyone here concerned that amarin CSO sold large % of his holdings ?
http://openinsider.com/search?q=amrn
i just wonder why ?
Once RI full results and details are disclosed at AHA and assuming that they will stand test of scrutiny (which I expect it to do ), revs will pick up smartly long before label expansion.
which doctor is going to withhold V from their patients and with patient pool so large well ... it's a give me and no brainer lol
le renard et les raisins par La Fontaine lol
from what I learned from ken sikaris md i expect amrn's announced RI top line results will pass scrutiny at AHA and beyond.
since V is already approved , if/when RI details stand the test of scientific reviews, revs will pick up long before label expansion. just my common sense tells me so.
whalatane, the patient population that amrn can target after RI is huge.
i am gonna let my 25Ksh bought on 8/27 ride and see where it will go lol