if it trades on an exchange......I trade it
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It looks like MM's are not trading today. It is a major holiday overseas, Ascension Day. It almost seems like the MM's are missing in action, based on today's MCET trading activity. That is a good sign.
MM's don't have enough shares. The public beat them in! I bought all my shares back on the close (.004) and they appeared red as a sell. Proof Mr. President, that all flippers and scare-dee-cat shares are absorbed by our MM friends. They (MM's) don't have the amount of shares they need.
mm's and the public take pps to .008-.014 before Fri close
9:30 yet
DON"T get caught_TODAY_withNOshares–Mark_iT! Easy possibility for a .20 cents situation, based on next weeks Largest European Cancer Immunotherapy Research And Development Meeting.
Key Words: Next Week.
MCET and VPRO NEWS!!!! $$$$$$$$$$$$$$$$$
huge_second leg_coming. mm's caught_with_there_pants_down
Friday gets .025 minimum, This is turning out to be a proven new area within the medical field.
I predict 90 million+ shares trade today
MM's have no shares!!!!!
Hey Rob, I think the company has been forced to sell before this, and the public was mixed. But anyway, it's all good! How do we get that loud, stinky fly out of the room? where is my fly swatter?
MCET ginormous news!!!
MM's have been dumping, Huge Squeeze gets us much Higher
next weeks medical conference on MCET breakthrough gets us near .05 cents
no pop, steady climb into next week well over .01 cents
Mcet has the patents, and now positive clinical data is a new, final factual road, which will change everything including pps. MCET just became a possible takeout target.
MCET NEWS!!! MultiCell Technologies Announces Positive Preclinical Results for MCT-465 and MCT-485 in Primary Liver Cancer In Vitro Models
WOONSOCKET, R.I., May 16, 2012 /PRNewswire via COMTEX/ -- MultiCell Technologies, Inc. (MCET) is pleased to announce representatives from the Company will present preclinical research findings for MCT-465 and MCT-485 at CIMT 2012 (http://meeting.cimt.eu), Europe's largest meeting dedicated to cancer immunotherapy research and development. CIMT 2012 will be held in May 23-25 in Mainz, Germany. The title of the poster presentation is: "Sharply discordant biological properties of synthetic noncoding dsRNA of different size: Translational opportunities in cancer." The poster presentation in the Enhancing Immunity session of the conference (poster number 078) will be made by Dr. Simona Bot, a consultant to the Company. The Company will present its findings during Poster Session I held on May 23rd, from 3:00-4:30 PM, and Poster Session II held on May 24th from 4:00-5:30 PM.
About MCT-465 and MCT-485
MCT-465 and MCT-485 are the first of a family of prospective cancer therapeutics based on the use of our patented TLR3 signaling technology. MCT-465 and MCT 485 are in preclinical development, and are being investigated as prospective treatments for primary liver cancer and triple negative breast cancer.
The immune system is composed of two synergistic elements: the innate immune system and the adaptive immune system. Stimulation of the innate immune system through key receptors, plays a critical role in triggering the adaptive immune response stimulating T and B cells to produce antibodies. In cancer, this integrated defense system does not work well, resulting in suboptimal activation of innate immunity and thus, late or inefficient adaptive immunity. The innate immune system is composed of a family of ten receptor molecules, the Toll-like Receptors (TLR1-TLR10), which act as sentries to identify invaders and signal the alarm to mobilize the body's array of immune defenses.
Within the tumor lesion, there may be infiltrating monocytes, dendritic cells and leukocytes in general, that have the capability to mobilize an adaptive or innate immune response but they are either silent or immune suppressive in the absence of select immune interventions. Such infiltrating non-cancerous immune cells may express TLR3, other TLRs, RIG-I and/or MDA-5. In addition, within tumor lesions, there may be cancerous cells or stromal cells or cancer stem cells which express TLR3, other TLRs, RIG-I and MDA-5 (representing RNA-sensing molecules).
Cancer stem cells are thought to play a role in a tumor's resistance to therapy. While significant progress has been made in developing cancer therapies that result in cytoreduction and thus tumor regression, the control of cancer over a longer interval and especially of metastatic disease, remains a key goal. Cancer stem cells are believed to be responsible for cancer relapse by being less sensitive to conventional therapies.
MultiCell owns exclusive rights to two issued U.S. patents (6,872,389 and 6,129,911), one U.S. patent application (U.S. 2006/0019387A1), and several corresponding issued and pending foreign patents and patent applications related to the isolation and differentiation of liver stem cells. The role of liver stem cells in the carcinogenic process has recently led to a new hypothesis that hepatocellular carcinoma arises by maturation arrest of liver stem cells.
Double stranded RNA provides a therapeutic avenue for cancer treatment through (a) activating intra-tumoral leukocytes, abrogating their immune suppressive activity and/or (b) interacting with cancerous cells and directly inducing apoptosis, or indirectly through mobilization of immune effector mechanisms.
MCT-465 is a high molecular weight synthetic dsRNA (polya:polyU)(polya:of 70bps) with immune enhancing properties. The mechanism of action of MCT-465 is pleiotropic and mediated by RNA sensors - such as TLR3, 7/8, MDA-5 and RIG-I - expressed by antigen presenting cells and select cases, by tumor cells:
Induction of pro-inflammatory, immune enhancing cytokines locally and systemically;
Anti-angiogenic effects through a local exposure to IL-12 / IFNgamma;
In select cases, direct pro-apoptotic anti-tumoral effect.
Prior studies with similar compounds support a strong immune enhancing effect of MCT-465, consisting in generation of Tc immunity against tumors, when administered as a companion to a vaccine. This raises the possibility that MCT-465 is an effective adjunctive therapy to any small molecule targeted therapy (such as tyrosine kinase inhibitors - TKIs) that results in release of endogenous tumor antigen while interfering minimally with the immune competence.
MCT-485 is a low molecular weight synthetic dsRNA (polya:polyU of 5bps) with direct tumor cytolytic properties. The mechanism of action of MCT-485 is pleiotropic yet distinct from that of MCT-465:
Induction of tumor cell death upon direct exposure, while normal cells are minimally affected.
Production of TNF-alpha by cancer cells resulting in amplified tumor cell death and a localized immune reaction that has the potential to generalize and curb progression of metastatic cancer.
About MultiCell Technologies, Inc.
MultiCell Technologies, Inc. is a clinical-stage biopharmaceutical company developing novel therapeutics and discovery tools that address unmet medical needs for the treatment of neurological disorders, hepatic disease and cancer. For more information about MultiCell Technologies, please visit http://www.multicelltech.com.
Caution Regarding Forward-Looking Statements
Any statements in this press release about MultiCell's expectations, beliefs, plans, objectives, assumptions or future events or performance are not historical facts and are forward-looking statements for purposes of the Private Securities Litigation Reform Act of 1995 (the "Act"). These statements are often, but not always, made through the use of words or phrases such as "believe", "will", "expect", "anticipate", "estimate", "intend", "plan", "forecast", "could", and "would". MultiCell bases these forward- looking statements on current expectations about future events. They involve known and unknown risks, uncertainties and assumptions that may cause actual results, levels of activity, performance or achievements to differ materially from those expressed or implied by any forward-looking statement. Some of the risks, uncertainties and assumptions that could cause actual results to differ materially from estimates or projections in the forward-looking statement include, but are not limited to, the risk that we might not achieve our anticipated clinical development milestones, receive regulatory approval, or successfully commercialize our products as expected, the market for our products will not grow as expected, and the risk that our products will not achieve expectations. For additional information about risks and uncertainties MultiCell faces, see documents that MultiCell files with the Securities and Exchange Commission, including MultiCell's report on Form 10-K for the fiscal year ended November 30, 2011, and all of MultiCell's quarterly and other periodic SEC filings. MultiCell claims the protection of the safe harbor for forward-looking statements under the Act and assumes no obligation and expressly disclaims any duty to update any forward-looking statement to reflect events or circumstances after the date of this news release or to reflect the occurrence of subsequent events.
SOURCE MultiCell Technologies, Inc.
.03 - .05 bagger Live Today!
News!!!! MultiCell Technologies Announces Positive Preclinical Results for MCT-465 and MCT-485 in Primary Liver Cancer In Vitro Models
WOONSOCKET, R.I., May 16, 2012 /PRNewswire via COMTEX/ -- MultiCell Technologies, Inc. (MCET) is pleased to announce representatives from the Company will present preclinical research findings for MCT-465 and MCT-485 at CIMT 2012 (http://meeting.cimt.eu), Europe's largest meeting dedicated to cancer immunotherapy research and development. CIMT 2012 will be held in May 23-25 in Mainz, Germany. The title of the poster presentation is: "Sharply discordant biological properties of synthetic noncoding dsRNA of different size: Translational opportunities in cancer." The poster presentation in the Enhancing Immunity session of the conference (poster number 078) will be made by Dr. Simona Bot, a consultant to the Company. The Company will present its findings during Poster Session I held on May 23rd, from 3:00-4:30 PM, and Poster Session II held on May 24th from 4:00-5:30 PM.
About MCT-465 and MCT-485
MCT-465 and MCT-485 are the first of a family of prospective cancer therapeutics based on the use of our patented TLR3 signaling technology. MCT-465 and MCT 485 are in preclinical development, and are being investigated as prospective treatments for primary liver cancer and triple negative breast cancer.
The immune system is composed of two synergistic elements: the innate immune system and the adaptive immune system. Stimulation of the innate immune system through key receptors, plays a critical role in triggering the adaptive immune response stimulating T and B cells to produce antibodies. In cancer, this integrated defense system does not work well, resulting in suboptimal activation of innate immunity and thus, late or inefficient adaptive immunity. The innate immune system is composed of a family of ten receptor molecules, the Toll-like Receptors (TLR1-TLR10), which act as sentries to identify invaders and signal the alarm to mobilize the body's array of immune defenses.
Within the tumor lesion, there may be infiltrating monocytes, dendritic cells and leukocytes in general, that have the capability to mobilize an adaptive or innate immune response but they are either silent or immune suppressive in the absence of select immune interventions. Such infiltrating non-cancerous immune cells may express TLR3, other TLRs, RIG-I and/or MDA-5. In addition, within tumor lesions, there may be cancerous cells or stromal cells or cancer stem cells which express TLR3, other TLRs, RIG-I and MDA-5 (representing RNA-sensing molecules).
Cancer stem cells are thought to play a role in a tumor's resistance to therapy. While significant progress has been made in developing cancer therapies that result in cytoreduction and thus tumor regression, the control of cancer over a longer interval and especially of metastatic disease, remains a key goal. Cancer stem cells are believed to be responsible for cancer relapse by being less sensitive to conventional therapies.
MultiCell owns exclusive rights to two issued U.S. patents (6,872,389 and 6,129,911), one U.S. patent application (U.S. 2006/0019387A1), and several corresponding issued and pending foreign patents and patent applications related to the isolation and differentiation of liver stem cells. The role of liver stem cells in the carcinogenic process has recently led to a new hypothesis that hepatocellular carcinoma arises by maturation arrest of liver stem cells.
Double stranded RNA provides a therapeutic avenue for cancer treatment through (a) activating intra-tumoral leukocytes, abrogating their immune suppressive activity and/or (b) interacting with cancerous cells and directly inducing apoptosis, or indirectly through mobilization of immune effector mechanisms.
MCT-465 is a high molecular weight synthetic dsRNA (polya:polyU)(polya:of 70bps) with immune enhancing properties. The mechanism of action of MCT-465 is pleiotropic and mediated by RNA sensors - such as TLR3, 7/8, MDA-5 and RIG-I - expressed by antigen presenting cells and select cases, by tumor cells:
Induction of pro-inflammatory, immune enhancing cytokines locally and systemically;
Anti-angiogenic effects through a local exposure to IL-12 / IFNgamma;
In select cases, direct pro-apoptotic anti-tumoral effect.
Prior studies with similar compounds support a strong immune enhancing effect of MCT-465, consisting in generation of Tc immunity against tumors, when administered as a companion to a vaccine. This raises the possibility that MCT-465 is an effective adjunctive therapy to any small molecule targeted therapy (such as tyrosine kinase inhibitors - TKIs) that results in release of endogenous tumor antigen while interfering minimally with the immune competence.
MCT-485 is a low molecular weight synthetic dsRNA (polya:polyU of 5bps) with direct tumor cytolytic properties. The mechanism of action of MCT-485 is pleiotropic yet distinct from that of MCT-465:
Induction of tumor cell death upon direct exposure, while normal cells are minimally affected.
Production of TNF-alpha by cancer cells resulting in amplified tumor cell death and a localized immune reaction that has the potential to generalize and curb progression of metastatic cancer.
About MultiCell Technologies, Inc.
MultiCell Technologies, Inc. is a clinical-stage biopharmaceutical company developing novel therapeutics and discovery tools that address unmet medical needs for the treatment of neurological disorders, hepatic disease and cancer. For more information about MultiCell Technologies, please visit http://www.multicelltech.com.
Caution Regarding Forward-Looking Statements
Any statements in this press release about MultiCell's expectations, beliefs, plans, objectives, assumptions or future events or performance are not historical facts and are forward-looking statements for purposes of the Private Securities Litigation Reform Act of 1995 (the "Act"). These statements are often, but not always, made through the use of words or phrases such as "believe", "will", "expect", "anticipate", "estimate", "intend", "plan", "forecast", "could", and "would". MultiCell bases these forward- looking statements on current expectations about future events. They involve known and unknown risks, uncertainties and assumptions that may cause actual results, levels of activity, performance or achievements to differ materially from those expressed or implied by any forward-looking statement. Some of the risks, uncertainties and assumptions that could cause actual results to differ materially from estimates or projections in the forward-looking statement include, but are not limited to, the risk that we might not achieve our anticipated clinical development milestones, receive regulatory approval, or successfully commercialize our products as expected, the market for our products will not grow as expected, and the risk that our products will not achieve expectations. For additional information about risks and uncertainties MultiCell faces, see documents that MultiCell files with the Securities and Exchange Commission, including MultiCell's report on Form 10-K for the fiscal year ended November 30, 2011, and all of MultiCell's quarterly and other periodic SEC filings. MultiCell claims the protection of the safe harbor for forward-looking statements under the Act and assumes no obligation and expressly disclaims any duty to update any forward-looking statement to reflect events or circumstances after the date of this news release or to reflect the occurrence of subsequent events.
SOURCE MultiCell Technologies, Inc.
i changed my position today, after horrible action
press oneday, and conference next, company is selling a lot of shares, and sold tons more today. conference calls are always the time too go for good and don't look back.
today was not good, I'm more cautious at this point, and I did lighten up on my pos
Hey Freakin Huge GOLDEN Cross, breached-in-progress$$$$$ !!!! the only thing we've done already, did that before, is below this level!!! Flip this and pay double UP!
RELM vol alert!
just kidding, but it is odd that this is the 4th time in the past few months that 100 shares traded for the day. We ( me and you )don't trade 100 shares, MM's funny business makes you wonder
A huge move into .008's_.015 approaching_checkout_the_Macd_on_chart_above.
when_the_realEstate_expansion_andPROOF_of_minerals/metals facts get revealed, pps will go greater than where this has been. welcome to the pennyland machine
DGRI steady climbing
DGRI Time . . 01 Higher
you gotta hold some big lot down here, for the cream of the crop, and the other half, flip. Might be huge pops, profit taking, huge pops, profit taking, into pennies.
there's a good chance all those shares won't be for sale anymore, as of yesterday.
Proof_of_Gold_in the properties_gets_pps_well_over_.015_to_2 cents minimum
more than likely, management has to raise money. They need to sell 25mill and my guess is half that is a fake wall. Today might be the last day to get in, before a nice move up.
Management raising money, patience prevails
anybody ever hear of EKWX
DGRI going to .06 cents the proof is in the mines they own
going back to .30 cents and for a good reason.
UNQT going back to .30 cents
Freakin_Proof_inThe_Pudding- HUGE. and a huge company event.
what do we get .015 tomorrow?
You_know_what, I_think_this_is_headed_towards .06 cents, shortly. Thats minimum evaluation, if I'm correct. There is always a chance of something else to prove me wrong, something I don't know about, within the company's numbers, or executives, but lets just see.