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Gotta buy nac.. embarrassed I still haven’t ordered..net flux terminal list good stuff!
Come on anavex .. get us the peer reviewed the bla the nda and accessssssssssss!!!!
Timber
You sound like stock investor ..
Good for you..
Unfortunately for me these conversations bore the hell out of me..
I wish you well when you are invested in positive future developments.. and I wish you failure when you bet against healthy successes.
Ignore
Yeah.. not a top priority for anavex review..
But reading the tea leaves..
Perhaps they should go back and rest before and after..now..
Not to devastate cassava..
But to find out if testing cassava as adjuvant makes sense
If they were. Not going to confirm they would never have attended this conference..
But still nice to hear again that our drug
has created Human Health History!
The Nobel prize should be coming forthwith..
God Bless you he Anavex Team
Yesterday had the privilege of meeting
botanical moguls and their father.
He suffers dementia..
he comes into office and joins them everyday..
Has physical therapists
Has full time personal care..
He Seemed quite aware to me.. not like my Father at 72..
I think my dementia started 10 years ago when emotional memory became detached from actual memory.. I could remember how something felt.. but I didn’t feel how something felt.. if that makes sense..
Pickleball was a struggle the other day,, not just serving bu the desire to compete.. that is a devastating loss for me.. hope it only temporary..
Anavex will be the answer for many, and I pray it is for me as well..
I would take cassavas drug right now! Continuously if I didn’t have access to Blarcamesine..
I would take annoviss drug right now( for limited a period of time)
But when Blarcamesine becomes available I will never stop taking it.. ever
But
I have posted under cassavas board answers.. if you want to continue conversation respond to those posts..
Last post was Biomarker..
Simufilam Significantly Improves Cognition in Patients with Alzheimer’s in Interim Analysis of Open-label Study at 9 Months
Cognition Improved 3.0 Points on ADAS-Cog at 9 Months (p<0.001)
Cognitive Improvements Track with Biomarker Improvements
No Behavior Disorders in Over 50% of Patients
No Safety Issues
Improvements in Cognition, Biomarkers and Behavior Suggest Highly Encouraging Treatment Effects
Oral Presentation at AAIC Today
AUSTIN, Texas, July 29, 2021 (GLOBE NEWSWIRE) -- Cassava Sciences, Inc. (Nasdaq: SAVA) announced positive clinical data today from an interim analysis of an open-label study with simufilam, the Company’s investigational drug for the treatment of Alzheimer’s disease.
In a clinical study funded by the National Institutes of Health (NIH), simufilam significantly improved cognition in Alzheimer’s patients, with no safety issues. Simufilam improved cognition scores 3.0 points on ADAS-Cog11, an 18% mean improvement, baseline to month 9 (p<0.001). This interim analysis summarizes clinical data from the first 50 patients with mild-to-moderate Alzheimer’s disease who completed 9 months of open-label simufilam treatment.
Cassava Sciences believes today’s data is the first report of significant cognitive improvements at 9 months that also track with robust improvements in biomarkers in patients with Alzheimer’s.
“We are very pleased with the overall consistency of data,” said Remi Barbier, President & CEO. “Simufilam improved cognition, biomarkers and behavior, a triple-win for study participants. These clinical data combined with a clean safety profile and easy oral administration suggest highly encouraging and durable treatment effects for people living with Alzheimer’s disease.”
Cassava’s phase 2 study showed that among 64 patients, those treated with sumifilam showed improvements in multiple disease-indicating biomarkers and cognition tests compared to patients treated with a placebo. Patients treated with 100mg of sumifilam showed an 18% decrease in total tau levels and a 14% increase in amyloid beta42 (in Alzheimer’s disease, tau levels are high and amyloid beta42 is low). The patients treated with sumifilam also showed improvements in memory tests, though these results were not statistically significant.
Timber..I will respond on proper board where y May review
Timber ignore the short stacks..
Incorrect on so many levels…
Cassava on first trial had higher response % than anavex.. but anavex super duper responders reaponded better.
Cassava appears from latest tea leaf to positively effect 62.5% of population -125. / 200 - very positively( we don’t know how positively yet just like we don’t know how well 50mg affected early AD but we know it was strong enough data to bring up the combined lesser effect of 30Mg to
Clinically meet endpoints - primary and secondary..
Does cellular hmoeoataiss automatically correct the issues which cassavas drug fixes?
Maybe cassava drug will make anavex drug more effective as well.. right?
Let’s run some models bio boys and girls!
This is where AI kicks ass
Think Ana are. And cassvava will work well as adjuvants..
The 50 Mg daily of Blarcamesine I believe will reduce the amount of cassava’s drug from 200 Mg daily..to half maybe?
Also cassava’s drug should only be necessary for say 2 months as my guess is the body’s cellular balancing repairs
The issues which cassava’s drug helps with.. maybe not..
Let’s get a trial started!
Also maybe each drug has a percentage of the population for which it’s drugs are not effective.. Let us hope and pray they are different cohorts…
When using guidance
of
PDD high dosage results..
Peer reviewed can’t happen quickly enough
This is beating them with both arms tied behind back..
Wait until 50mg dose separated..
Exactly
Stating once again
We met primary and secondary endpoints
Let the blood bath begin..
17,000,000
Make them pay
Bbbbbbbabamm
I think a lot of people when first reading study think it’s 100 pateienta in each arm..
Placebo vs treatment..
But obviously ( or not so!) it’s not the case at all
Sa couldn’t wait for pr…Despite positive “spin” of meeting endpoints.. haha
doing what billions and billions of $$ BP research could not..
Anavex has not responded to FT ( tuk Fard) AF illegitimate distortions..
Or as SA shill calls it anomaly.. what a riot.. trying to get out in front of presentation when again Anavex will repeat confirmation that they met TLD primary and secondary endpoints..
Did they stutter?
Haha..
Shorts feeling it.. firing too early to cover retreat..
I think the peer reviewed begins a new world for anavex.. it’s the Declarion of Indepence so to speak..
All other efforts will be needed to continue and further bludgeon the short sellers..
I see an Arsenal and Fortifications..
So our Army doesn’t outrun it’s supply chain in Russia in the middle of winter..
We are preparing for total and complete annhilation of the wicked
Cassava basically doing same thing
It’s not an accident
The 17,000,000 shares sold short pay to
protect their investment every time
a pr is released..
That is why I don’t think we see another
or until peer reviewed
I think until
Peer Reviewed confirmation
we don’t see another pr..
True..
Just sounds like fear..
But they have kicked our ads the last five years., fear is reasonable
Considering that at first computer models showed a2-73 as potential adjuvant for DPZ.. it would make sense that DPZ being a negative is not a leading thought by anavex.. the data will tell us..
I didn’t realize they separated DPZ Naieve in 2b/3 da
Bas.. so now you helping them ?
It is frustrating and hard not to be the best dog when the master picks up a stick..
Or when Lucy says she will hold the football..
This doesn’t mean that we should fear trying to kick the football!
Or chase the stick when TGD throws it!
Our forces are growing!
George.?
Why do you insist that this is anything other than a corporate presentation?
They have already announced TLD
Met endpoints..
I agree..in that …
They will say that again.
But they have said for over 5 years that Blarcamesine restores cellular homeostasis..
We will see TLR when it is peer reviewed and ready for NDA..and marketing..
Not before
Foo think YOU single handedly
added $200 million to cassava..
Meant that U in last post..
What a difference a letter makes..
That is unbelievable!
18,000,000 sold shares?
What a crock marxist crud
For those investors here that like tea leaves, you should read the tea leaf Foo posted on cassava board..
Does anyone here think cassava drug will be affecting the same low hanging fruit as Blarcamesine or when they are combined
the rwspinse will bring in an even greater response?
I think that is where this is going!
The good news for anavex is
We don’t compete as we simply engage the Human Health system! One would think A cellular homeopathically balanced system will just make other succesful drugs more potent..
But would really like to hear say from ‘Mayo’ or any of the deeper biosci’s what they think the adjunctive combo might realize..
Then of course there is always annovis!
To clear the board for a restart!
Try explains to a little girls family
that suffer Rett Syndrome , to her mother or father, that you make your living
shorting a bio Pharma sticks trying to save their little girl and that you have to say bad untrue things about them and their drug to make money.
I will let her father decide your judgement and penalty. Or her mother..
You may choose you wicked wicked person. Stop it !
Sorry mauismart.. I ignore all of them
Was JP Morgan the company that conspired with Epstein?
https://m.washingtontimes.com/news/2023/jan/3/virgin-islands-prosecutor-fired-after-accusing-jpm/
No one
Not until “peer reviewed “ is available will we see TLR..
Power
I can’t caution you enough about your theory. It is not shared by the company.
Your 50mg rockstar response is supported.
But not your DPZ Naieve theory..
I don’t think you are right
George
Peer reviewed will not be completed by then. I don’t think we see 50Mg group until peer reviewed complete.
I disagree with your timeline
It’s hilarious to watch the attention she’ll game..
Those blots are meaningless!
100%! Meaningless !
Like anavex was a printer company! Who gives a rats petutte!
No one!
Move on to relevance all you ink blot affiviandos your knowledge is absolutely pointless.. just terribly misdirected focus..imo
I would have liked Anavex’s entire presentation. To be an inkblot!
How do you inkblot
God’s Smile?
Almost all enjoy, as their are some who
really studied inkblots and they know their
Inkblots better than most and were cassava to save over 60% of dementia patients why they would just
Inkblot all over themselves
I too reviewed those western inkblots from a decade ago!!! And I have studied many many inkblots! Most have been in the form of early writings with terrible
punctuation and grammar, but nonetheless have I intensely reviewed them.
The inkblots from cassava, were black on a white background. This infers blackness shows up on whiteness and is our first clue!
Secondly, the inkblots didn’t form any known language or distinct communications characteristics( like hieroglyphs or the such). The white background does not appear to be papyrus so the inkblots are post Egyptian Gods..
After dosing my Sherlock Holmes elixir, and chasing it down with my Poireau smoke the best I can make of cassava inkblots are of a morphing mouse and butterfly. This can only mean one thing!
It is the year that mice will fly!
Having reviewed cassava’s drug, I just don’t think it will make mice fly!! Therefor the inkblots are a damndable lie!
However their drug does appear to have over a 60% success rate based on the number of patients 125 selected out of their 200 to advance in their most recent ongoing clinical trial.
If over 60% get better after a year.. in Alzheimers treatment .. that would make for a pretty good inkblot!
Of $ and a lot of smiles for the dementia suffering.
Now that is an inkblot we may all enjoy(almost)
Thx Foo
Still over 60% response nice
The longer we wait the more forceful the impact.. imo..
The more the wave gathers force with data from OLE in three different trials
..
I think TGD planning on leaving little room for detractors and a lot of ammo for
Regulators to be quick on approval…
As our progress stacks up waiting for delivery other projects stack up in line behind what we already knew was coming..
It’s going to be an exciting year