JohnCappelloFeb 12th, 9:01 am
$AMRN 3 new patents : METHODS OF REDUCING THE RISK OF A CARDIOVASCULAR EVENT IN A SUBJECT ON STATIN THERAPY 16/005,852 16/005,969 16/006,003

ILT

JohnCappelloFeb 12th, 9:08 am
$AMRN granted MOA patent METHODS OF REDUCING OR PREVENTING OXIDATION OF SMALL DENSE LDL OR MEMBRANE POLYUNSATURATED FATTY ACIDS 15/312,113

ILT

JohnCappelloFeb 12th, 9:12 am
$AMRN 1/30/19 granted COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OBESITY IN A SUBJECT IN NEED THEREOF 15/013,544
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ILT

Flipper44, I've provided Janet Woodcock's FDA Admin page below. "She has proven to be responsive, as I've seen her reply to an Amarin MB member." You're right, NVCR has a disproportionate advantage over our small company, and why not take advantage of any tools at our disposal, especially, as it doesn't cost anything to communicate? Furthermore, your observations of the Strupp trial is egregious enough to justify a citizen's petition, IMO.

https://www.fda.gov/AboutFDA/CentersOffices/ucm193984.htm

Thanks for all you do.

ILT

BB, thanks I found the earlier post on this subject discussed: post:121101

But it doesn't explain the expense risk reward of undertaking the trial...

ILT

Thank you.

BB.

Can you please explain the basis for the infringement, since Epanova is a mixture vs Amarin is not?

Thanks
ILT

For the physicians on this MB writing scripts, my brother shared an interesting approach he recently adapted for Prior-Authorizations. He found a small Mom-Pop Pharmacy near his practice that's doing Prior-authorizations and delivering the medications to the patient. Two patients were approved just yesterday alone. However, when the pharmacy went to deliver the meds, the patients declined to accept the meds because they weren't filled at their local pharmacy. I know, that's bizarre. Bro told the pharmacy not to worry, "just bring the meds to his office, and he'll get his patients to accept them". I'm sure his office staff is loving it!

ILT

How would these same authors explain 19% RRR in Jesus with no MO in Placebo? Ahhhhh..well, let me see...."

ILT

...."Intervention Study (JELIS) found no benefit in CVD risk reduction in relation to baseline TG. ..."



ILT

CD,

I saw a friend of mine at the gym this morning. I'd say he's around 65, 6'3"ish, skinny as a rail, and has always eaten healthy. He used to run, but he has some issues with his back I believe. He does the treadmill walking and some light resistance stuff. How often I don't know? He told me that he has cardiovascular disease "genetic". Something about having 70% blockage, and adding, that anything invasive could be risky for him based on where his blockage is. I asked if he's on Statin, I guessed Crestor? Yes, he's on 20mgs. I asked if he was on Vascepa? Yes, started a month ago. I know you don't have enough data, but I wonder what his future prospects are? Can Statin and Vascepa alone provide longevity?

ILT

Bfost,

What's with the rigidity to adhere to 5 years? What possible argument could support that? Just as well, this train will soon be unstoppable. It's going to be real fun watching the PPS rise higher and higher.

ILT

CD,

The medical establishment will have to revise it's guidelines once Vascepa gets the expanded label, that is, if the establishment wants to retain it's standing. Moreover, to uphold it's duty to protect patients.

ILT

Agreed! Thanks for clarifying.

ILT

CD, shared your survey experience with Bro. He thought it was great. What's there not to like, right? He added, he's never been marketed directly from the company that way. It's often you'll have an independent company conducting a survey. Go Amarin.

ILT

Ike, we owe you a great debt of gratitude. Great job!

ILT

Customer acquisition cost $500 bucks for roughly 3 scripts to break even. All green recurring rev going forward.

ILT

On the subject of patent infringement: I don't see being at all concerned with DS companies touting high concentrations of EPA, purity, etc. "The devil is in the details". If anyone has glossed over the dizzying long list of patents, particularly, any that cover the prevention of oxidation, rest assured, these companies cannot deliver or claim to deliver, a product that's free of oxidation. Amarin spent "millions and millions" over the years to get to that point of refinement. As long as OTC products don't have to submit to the same vigors as pharma grade products, the danger is not so much what their labels claim, as it is everything else they don't and need not say. "Russian Roulette anyone"? No thank you.

ILT

Raf,

It could also be said, that retail longs enjoy opportunities to get in cheap, when otherwise they wouldn't, for the same reasons we find ourselves waiting for everyone else to catch up.

ILT

That is brilliant! Thanks for sharing.

ILT

CD, awesome! Thanks for sharing.

ILT

Raf - your points are certainly reasonable. We can take solace in knowing that we have a handful of dedicated, super informative posters on Twitter, who do a super job at spreading very positive and informed posts.

ILT

Raf,

Quote: "I reached out to IR to ask them why the lack of social media presence. The reply was something like: sorry but we can't share our reasoning yet"

I wonder what that means?

ILT

CD, FYI people here don't know your name.

ILT

CD,

I would have the patient call the so called cardio and say flat out, that if he's harmed as a result of the rejection, he will sue him and CVS. See how fast this idiot turns on a dime.

JMO
ILT

CD,

WOW! I can picture your anger! and just how disturbing this ridiculous exchange was for you. If this guy was a Cardio, why would he cite having a masters degree in public health to understand drug trial designs? The more he said, the more preposterous he sounded. This idiot openly rejects Reduce-it trial results. Even worse, it shows erroneous attacks on positive trial results can have lasting effects on the minds of those beyond the investment community.

Think about this a moment. Ill-conceived commentary from influential professionals can cause people to "die", and "not just lose money in the market". I'm afraid to say, and I have no doubt it's true, that this idiot at CVS is not an anomaly. This episode is so faith breaking, that I wonder if an expanded label would change the minds of such dangerous characters in positions making life and death decisions. Scary!! This Cardio should be pursued. It would be a great disservice to the community at large to allow this idiot to continue working at CVS.

ILT

Ditto, great work!

ILT

Over the last four years, I've gone through the mail order option, so the correspondence has been with Representatives in many cases really going to bat for me. They're highly focused on getting immediate gratification through the phone survey feedback system. I always give them 10's which I'm sure carrys over to the next customer.

ILT

Massasulo52,

You raise an interesting point. When I receive a rejection of any kind, I go full on with the provider. I participate in the appeals process as much as I'm allowed to. This has worked for me in the past more than it hasn't.

ILT

Bfost, thanks!

ILT

Note: From the feedback I received, KOWA barely mentioned "V". They were focused on their own drugs. Going forward,the weakest links in the new force should easily outperform their predecessors by a wide margin.

ILT

Note: There were 500 reps at the three day conference. 100 more than the 400 hundred PR'd earlier. BIG DIFFERENCE:)

ILT

Distinguished Senior Cardiologist's life robbed by the very disease he was dedicated to treating:

http://www.israelnationalnews.com/News/News.aspx/258318

The world needs Vascepa without a moment to spare. RIP!

ILT

csfish,

Thanks, but FYI link doesn't work:(

ILT

Been doing it for 20 years. Best decision I ever made.

ILT

That's hilarious:)

CD,

Great. Sounds encouraging, as my concern was tied to a single sample. Hope your experience is more common.

Dinners are fertile grounds to get physicians amped up about investing in Vascepa. Letting them know it's an opportunity of a lifetime would kick their scripts into even higher gear:)

ILT

CBB,

I don't buy it. That's why I wanted a physician's opinion.

ILT

Dfc, do you really think insurers would cover for prevention of red face due to alcohol consumption? Tough call:)

ILT

I wish you all the best!

ILT