I have 3 questions for the board:

1). Will we ever see the full PDD data, or can we presume that it did not meet stat sig (similar to Rett) and has been swept under the rug?

2). Has Missling already released the market “surprise” information that he alluded to in the 2023 Aug CC (brain volume retention, genome heat map, EMA LOI, Rett readout), or is it something else that is yet to be released?

3). When is the recording of the JPM Investor Conference going to be available on the website?

Yes, he was only “Luke”-warm about the company’s prospects (couldn’t resist).

I have no idea why he left—maybe he saw the same warts that many of us shareholders are now seeing.

Correct, and many shareholdes are likely to transituon their shares into cash and bail.

Our CEO needs to be put out to pasture.

Some advice: don’t get too excited and temper your expectations. This way, you may be pleasantly surprised rather than disappointed.

Good luck to us—something has been telling me for awhile we’re going to need it!

Thanks for nominating me to “the list.” I feel like Andy Dufrane from The Shawshank Redemption. I speak the truth, and for that I get labelled a malcontent. WGT just wants to keep dreaming about sugar plum fairies.

Perhaps this consternation should be directed at the person most responsible for our predicament—DM. Release the full ALZ data, Missling. 13 months and counting—unacceptable.

Please explain to me what is the value of holding a patent IF the patented drug is not approved for any CNS indication?

These patent PRs are all fine and good, but we really need to see the AD & PDD complete datasets. Let’s get it all out in the open—no more obfuscation and speculation. We may as well show to one and all what we (may) have.

Yes, and there are aliens on your rooftop.

Enough of the conspiracy BS. You’ve read too many Basparks messages.

DM stated HIMSELF during CCs that it is harder to see positive Rett results in an adult population. The adult Avatar results gave him false confidence.

One of his many blunders and miscalculations.

Great news! Now let’s wait another 10 years for A3-71 to possibly be granted approval and generate revenue.

If A2-73 does not get approval in any CNS conditions within 18-24 months, this company will be but a footnote in 5 years.

Thus the reason we need a strong CEO for this most critical juncture. Hopefully the BOD does what is necessary to bring this to fruition.

On a side note, there appears to be a lack of humility from the “science experts” on this board. I guess they take their lead from DM, who just oozes arrogance and omnipotence. Comments such as “I only need 3 patients to measure statistical significance” & “we have never had a trial failure” must ring hollow now.

To summarize your post, DM needs to lose his arrogant, condescending, and obtuse way of communicating to his stakeholders (shareholders & all others that are either financially or emotionally invested in this company). Stop with the riddles (tip of the iceberg, you’ll see why we did it this way, yet unnamed CNS condition, surprise the market) BS and deliver data that can be viewed, analyzed, tested, and validated.

Stop the fluff PRs about Partex AI nonsense and genome heat maps which do nothing other than distract and undermine any semblance of credibility. If DM does not start to do this beginning next week at the JPM conference, then the BOD has a fiduciary obligation to remove him as CEO. Give him some advisory role, and let’s get someone who is a competent, eloquent, and effective leader and communicator.

The stakes are too high to have this clown as our CEO— he really has become an embarrassment.

Are you Vivek Ramaswamy by chance?

“The Anavex Office (virtual or not) must have been very chaotic.

You must be referring to the Custodial Staff’s storage office that is shared by Anavex HQ.

The only thing delivered on time at Anavex is Chris’ bloated salary & options package.

It’s probably in the same place the promised but long forgotten full PDD results are.

A patent does not grant a company exclusive rights to manufacture it in perpetuity. They would have at least 10 years if Missling can ever get it across the finish line before generics would be available.

Meaningless PRs to placate the masses does seem to be Missling’s MO. The one that rises above the others is that BS Partex Group AI Partnership announcement back in August. Missling came up with the ingenious idea to combine the desire for a partner with the hot buzzword of AI.

It’s PRs such as this that only serve to undermine his credibility.

No worries—according to Dr. M, we’re going for shitsofrenia. I think it’s similar to diarrea.

The “integrity” of the FDA was also said to be true for people working under the 9 Supreme Court Justices (sworn to confidentiality), and yet a decision leaked out in 2022 before the official decision was announced. By the way, the leaker has never been identified, even though there were only 30 people who knew of it. It sure makes you cynical of once sacred institutions.

Onto my quarterly complaint of our CEO Misling. I think AF was being kind by only placing him on the (Dis) honorable mention list. He is truly deserving of being grouped with the Worst CEOs. This guy’s business instincts just seem lousy. Today would have been the perfect day to release the Rett Excellence Data as a follow up to Wednesday’s Avatar PR. I was pretty sure that Wednesday’s release was in fact setting the table for this 1-2 punch. Instead, Missling once again fumbled on the 1 yard line. I really just don’t get how this guy operates. There has to be a more competent person who can lead us to the next phase. I hope the BOD will seriously consider replacing him in 2024. Enough already.

I can’t really argue with Missling being on AF’s (Dis)Honorable Mention list of CEOs. Even from solely a communication standpoint, he is awful. Perhaps this will soon change, but up until now he gets an F minus.

I’ve been waiting since 2015….I’m one of those impatient investors.

Huh? I don’t think so, George.

Carry on.

What about TAX LOSS SELLING as the year comes to a close? I didn’t see that mentioned in your “analysis.” Without our “surprise” that was mentioned during the August CC, this will drift lower into YE (all IMO, of course).

How is the Partex Group AI Partnership going? Crickets……

Despite what some have labelled Doc, I find his posts to be very informative and insightful.

Keep up the great work, Doc. You are an extremely valuable asset to this board, as well as a logical counterbalance to the blind devotion of the WGT group.

Today, music has lost one of its most brilliant songwriters in Shane MacGowan. As my screen name implies, I am a big fan of the beautiful music he and The Pogues created over the past 40 years.

RIP, Shaney Mac!

Partnership was already announced in August—Partex Group.

You may want to temper your expectations—better to set the bar low and be surprised.

Most definitely—Soumit Roy is more a cheerleader than a hard hitting analyst. Missling’s typical opening “we hope you are as excited as we are” krap has gotten stake. Soumit’s “congratulations on all the progress” has also worn thin as well.

Let’s hope that there might be at least another analyst on the call in addition to Roy, who might actually ask a question that forces Missling out of his comfort zone.

I have the Over/Under for this CC at 18 minutes.

So what exactly was the “surprise the market” news that Missling alluded to in the last CC in early August?

Was it already released and noone noticed? Has it yet to be released and therefore will be by year end?

Once again more questions than definitive answers.

The market closes at 1 pm tomorrow, not 12.

Not that it matters all that much.

Dr. Missling’s is a master at blowing smoke up the WGT crowd’s derrieres. Two more fluff PR’s to add to the talking points for the next cc.

Still we wait fir the following:

PDD full data readout—2+ years and counting
AD full data readout—1 year and counting
RETT data readout—6 months and counting

See a pattern? By the way, now is the Partex Group AI Partnership going? What a joke!

Let’s not forget one of DM’s favorite lines:

You’ll know why we did what we did.

I guess that can be open to 2 completely different interpretations.

If DM doesn’t wind up in jail, his next career move should be as a politician. He is the master of double speaking.

We’ll probably have to extradite him from Germany.

I’ll gladly be the lead plaintiff!

Congratulations on the sub $6 closing everyone.

I HOPE YOU ARE AS EXCITED AS WE ARE! CM

CONGRATULATIONS ON ALL THE PROGRESS, CHRISTOPHER! Soumit Roy, the one (and only) analyst on August 8 CC.

What a bunch of buffoons.

Don’t you know by now that unless it’s Anavex’s compound, everything else is schitt!

And who hired the CRO to run the trials?

When you’re the CEO, the buck starts and stops with you.

“Tell us why the shorties and their wives are not at risk for this scenario?”

That’s an easy one, bird of prey. We have Dr. Missling as our CEO.

We’re due for another fireside chat announcement. Maybe Partex Group can participate alongside us this time. After all, they are our partner.

What a joke this company is.

Let’s be more clear on partnerships. We need a partner that will provide some upfront cash and/or equity, NOT the BS Partex Group type partnership which was nothing more than a bullet point that Missling could mention in August’s CC.

Bas, BS like this is ALSO why we’re floundering at a $500M market cap and sinking.

I HOPE YOU ARE EXCITED AS WE ARE!!

You don’t seem too excited.

Don’t worry, we’ve got Partex Group as our partner!

Last one out, turn off the lights.

So what has changed this week?

For one, the SP continues to decline--or does that not matter.