Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
We conclude that squeaking in ceramic-on-ceramic THA could be related to a poor accuracy of 3D hip anatomy reconstruction which generated a posterior impingement and subsequent anterior edge loading because of excessive global anteversion.
Researching Squeaking I have not uncovered the problem being directly related to Ceramic on Ceramic. Poor manufacturing tolerance, off label use, improper placement. If something is squeaking it's indicating a problem. By all means put in the plastic to hide the problem. No squeak same underlying problem leading to increased wear particulate.
I jumped the gun and heard manufacturing and Ceramic slurries. The more I look at the job title the more I`m thinking the ceramic slurry is in relation to investment casting chrome cobalt. Hmm I thought that was all machining bar stock. Looks more like they are doubling down on Chrome Cobalt. Let's hope they plan on SiNi coating these or we need to edit the straight out of compton logo to straight out of business for Zimmer.
That engineer oversees manufacturing. Not R&D. Well maybe he needs ceramic slurries for injection molding Chrome cobalt?
You trying to get me to say this so you dont have to? because I will. What you`re posting is highly suspicious on the Zimmer front considering their strategic partner was never announced and Hips where projected to launch 2018,2019 on clearance according to their PR's.
The ceramedic lawsuits are against Ceramtec for violating their patents. The lawsuits against Zimmer and Biomet and anyone that uses Biolox delta is "hey, you also owe me money". So unless this has something to do with HA tricalcium phosphate, Hiring a Engineer to oversee manufacturing of ceramics indicates to me they are doubling down on their ceramedic lawsuit by bringing ceramic manufacturing in house, away from Ceramtec or they're working on a potential replacement of Biolox delta, perhaps. If true is this a unique blend of Alumina oxide ceramic that doesnt increase litigation between Ceramtec,Ceramedic etc..OR, they are looking at a new generation of Biolox that is better then gen1 gen2. Perhaps a completely different material based on years of development?
Supporting manufacturing processes related to investment casting including but not limited to: wax injection molding, formulation of ceramic slurry,
Within R&D?
Manufacturing Senior Engineer II
Supporting manufacturing processes
Dilution? developing position?
https://fintel.io/so/us/amda
fintel reports an N-Q from invesco indicating an underlying security
https://fintel.io/doc/sec/1209466/000119312518287385/d618711dnq.htm
Good luck finding who owns this underlying position. This suggests to me not only that preferred may not be being converted but it may not be being dumped onto an open market. Looks like it's being added to the portfolios to me. Not something you would do unless you somewhat believed in the long term health of a company. Looks like Dilution and Death spiral financing is a boogey man to me.
Checked the news cycle and nothing looks new. My guess is funds coming out of MagneGas profits today and going into AMDA. There's some cross posting going on between the two tickers on ST. Just a basic recognition of market potentials. The more they can paint this as having no value beyond a worthless pump and dump the better for them.
From my research I think squeaking is a diversionary tactic that is mitigated beyond material. In fact squeaking is an indicator of wear. Think of Cobalt Chrome as a silent killer. No squeak same wear.
I was playing devils advocate a bit as far as phase changing in vivo increasing cracking of SiNi like biolox. Looking at the patents it's obvious they where attempting a novel formulation of Alumina oxide based ceramics to mitigate phase changes that promote cracking and took a left turn into SiNi went down the rabbit hole and never looked back. However, it is prudent to be cautious without the 10 year in vivo results we're not on a level playing field.
https://www.hindawi.com/journals/crior/2017/9123684/
Do we have data on SiNi Ceramic on Ceramic hips at the 10 year mark?
After a fracture of a ceramic component, both surgeon and patients may be reluctant to implant another CoC articulation given concerns about a refracture
A clear discrepancy between predicted in vitro and actual in vivo surface phase stability of BIOLOX®delta
Previously I`ve mentioned Copper in the OR and covering everything including the bathroom and OR table in copper coating. One of the problems with copper coatings I see is wear thru of the coating back to the base stainless steel material. With a deeper understanding of SiNi coatings, I realize now that it's more similar to a thin film like anodization of aluminum rather than a thick coating. With the hardness of SiNi on the Mohs scale I surmise less wear through of a SiNi plated material than a copper plated material. Using Bal's analogy of the tire store I don't see a unit that couldn't potentially benefit. From SiNi plating the screws to Drill body.
With US Spine why did they not use them as a testing ground? plating screws, plates and doping PEEK? I surmise this was their intention but where limited by financials. Unlike US Spine, CTL would operate as a separate entity while absorbing US spine. In my opinion CTL would need this development as much as Amedica to adopt into their own product lines to compete against their competition. A second driving force like Sonny mentioned with the train analogy.
CTL + Amedica presents a threat. Will they nip it in the bud or let the threat develop? Allowing this threat to develop would create a bigger buy out package, but what would be merged would be farther along in development.
For my own benefit I think I've scattered enough puzzle pieces about. Alot of these rabbit holes may be interconnected or dead ends. That may look misleading to some. I`m not seeing any new rabbit holes to run down I haven't already exhausted. In hindsight, I think my focus has been a bit narrow minded in the direct application of cortical and cancellous ceramic material, besides a bit of speculation on HA tricalcium phosphate doping. I have neglected the potential of SiNi coatings and plastic doping.
On the topic of coatings think anodization. If a Dr. is dead set on using a PEEK spinal implant or a Cobalt Chrome Hip with a PEEK insert. Perhaps he's "used to it" he's been using these implants for years and feels he can trust them and doesn't feel like risking his career innovating. Or he hears the word ceramic and relates this to shattering and doesn't want to hear anymore and has no time to be educated on the difference of ceramicised metals and SiNi. SiNi doping of a Peek spinal cage or SiNi coating the femoral head and stem of a Cobalt Chrome implant offers an "in" to get the benefits into the patient without depending on the doctors prowess or willingness for change.
I think Amedica is 2 steps ahead of me here with their direction.
I think it was Chon that stated a merger would require taking Amedica private or listing CTL on the market. Things he was not too interested in. Seems like that was discussed already.
http://www.level2stockquotes.com/
Heres what Im using to watch the bid ask for free.
Looks like it was Aug. 28th opening from my records. All I can see back there is the high low price for the day, which just happens to be my market buy I threw without a limit buy and the accidental "stop loss" I immediately pulled. It broke my ticker for the rest of the day as the price sat at .40 on the minute then jumped up to correct for actual volume and slowly walked down the rest of the day. I think you had to watch it real time on a line ticker to notice it. You can try to simulate the actions on a low volume day to see if you can break it again.
I noticed this. Maybe a few weeks ago I accidentally placed a low ball ask thinking I was placing a bid then immediately pulled it and revised to a bid. Then threw the rest of my buy at an open market bid. Somehow this broke the bot and it spent the rest of the day hunting the low ask and high bid causing the ticker to swing wildly as it hunted my "stop loss" and sold at the high bid. I have never broken a ticker before. When looking to buy low this is my holy grail, when a price separates from reality. Efficient market theory my butt. That guy must have never met a robot before.
Looks like ConforMIS slammed dunked on Smith & Nephew on patent lawsuits recently. How does this effect Amedica? Well one Bal is a consultant for Conformis hips. Unless you live under a rock any implant company realizes the added value Amedicas material licensed IP can offer. This is a Financial and market share windfall for Conformis who seems to be taking market share away hand over fist. When looking specifically to bless the hands of the doctors with your tech in an ever changing market it would be foolish to align your future prospects too directly with the future prospects of another company. You might just be tying yourself down to a sinking ship. Unless your focus is poor and too near sighted, you may be focused on a cash lump sum and sacrifice the macrocosm for the microcosm. That's my take on it. Why limit yourself? If dr's want to use H1 product design or the custom fit IP of Conformis? Should their choice be limited by materials? For the sake of technological advancement and humanity I don't think their choices should be limited by company or competition. If a surgeon wants H1 SiNi Custom fit the companies should be forced by the government to get along with each other enough to make that happen. This is like a basketball team that wants to shove each other around in an attempt to grand stand on the court playing on a world stage of organized teams.
https://www.pveducation.org/pvcdrom/anti-reflection-coating-color
Silicon Nitride Coating. With a similar chemical composition as our other forms of silicon nitride, this form of silicon nitride can be applied as an adherent coating to metallic substrates, including cobalt-chromium, titanium and steel alloys. We believe applying an extremely thin layer of silicon nitride as a coating may provide a highly wear-resistant articulation surface, such as on femoral heads, which may reduce problems associated with metal or polymer wear debris. We also believe that the silicon nitride coating can be applied to devices that require firm fixation and functional connections between the device or implant and the surrounding tissue, such as hip stems and screws. The use of silicon nitride coating may also create an antibacterial barrier between the device and the adjacent bone or tissue.
Together with a strategic partner, we have initiated biomechanical testing of our solid silicon nitride femoral heads. The results of this test will be released in 2017. If the tests indicate that silicon nitride femoral heads are superior in terms of wear performance, taper corrosion, strength and in vitro hydrothermal stability, we eventually intend to commercialize this product in cooperation with a strategic partner. However, clearance of these types of devices by the FDA will be required. Currently, the FDA has indicated that a limited one to two year clinical trial may be necessary to obtain clearance. If clearance is eventually obtained, we intend to commercially launch products for use in total hip replacement in 2018 or 2019.
we intend to initiate biomechanical testing with a strategic partner for silicon nitride components for use in knee replacement procedures to support a 510(k) submission to the FDA.
We obtain our non-silicon nitride spinal fixation products and instruments from third-party manufacturers.
We seek to protect the trade secrets in our proprietary technology and processes, in part, by entering into confidentiality agreements with commercial partners
We believe our main competitors in the orthopedic implant market, which utilize a variety of competitive biomaterials, include: Medtronic, Inc.; DePuy Synthes Companies, a group of Johnson & Johnson companies; Stryker Corporation; Biomet, Inc.; Zimmer Holdings, Inc.; Smith & Nephew plc; and Aesculap Inc. Presently, these companies buy ceramic components on an OEM basis from manufacturers such as CeramTec, Kyocera and CoorTek, Inc., among others. We anticipate that these and other orthopedic companies and OEMs will seek to introduce new biomaterials and products that compete with ours.
apparently I'm you too.Might be Suffering from multiple personality disorder and dont realize Im everybody?
Who gets to slide into 2nd base today? Boston745? Lou745? Smoker745? Coach CL101
ah man, now I dont even know what I caught on to.
https://books.google.com/books?id=g6_ACwAAQBAJ&pg=PA125&lpg=PA125&dq=Ceramtec+Salt+lake+city&source=bl&ots=y5j2VXFOvh&sig=40e9bqsS5dpUCSuD6Q4s61IZYyk&hl=en&sa=X&ved=2ahUKEwiQ8OTxzNbdAhXPqlMKHZcfAbEQ6AEwBnoECAQQAQ#v=onepage&q=Ceramtec%20Salt%20lake%20city&f=false
Found this and noticed they give thanks to amedica donating financing or materials at the bottom. page 125. Looking for "Ceramtec" Salt lake city. Noticed American Elements has bases in salt lake along with amedica and coorstek.
They're calling it "ceramacized metals" I absolutely agree. If it's now illegal to call almond milk milk because you cant milk an almond they shouldnt be allowed to call their products a true ceramic. AMDA should be the only company allowed to call their product a ceramic.
ah, you got me. If you have to be on american elements list, they got saint gobain.
"Zimmer had voluntarily recalled the affected Saint- Gobain products in August, 2001."
CoorsTek signed an agreement in June 2010 to buy certain assets of the Advanced Ceramics division of the French conglomerate Saint-Gobain.[47],[48] The Advanced Ceramics division employed 1200 workers worldwide, and 500 at six North American sites, at the time. CoorsTek gained ownership of several longtime competing brands, such as Cerbec Si3N4 bearings, Solcera and Cerastat. The transaction was completed in January 2011, with CoorsTek assuming ownership of six plants in Europe; four in the USA; one each in Canada, Mexico and Brazil; and sales offices in Japan, China, Taiwan and Singapore. The acquisition gave CoorsTek a total of 44 facilities on four continents, and increased capabilities in SiC, Si3N4, mullite and steatite.[49] Compagnie de Saint-Gobain retained ownership of its 22 High-Performance Refractories, Lo-Mass®, Carborundum Abrasive Products and Hexoloy® SiC products business sites.
If there was a deal being mulled over you dont think Zimmer wouldnt chunk them the price of spine? Sonny said on CC the companies they thought about selling to nobody wanted both the retail spine and manufacturing. Just one or the other. I`m calling BS. I think CTL made sense for so many other reasons including the fact they didn't mind licensing agreements.
In prison you can be the girlfriend or the husband. Amedica needed a prison girlfriend not a prison husband. A prison Husband tells you what to do. CTL makes a great prison girlfriend.
Synergy between McEntyre Sonny and now Chon. The only way I would let that work is bring in Lisa Su as CEO and make Sonny the other CTO. Sonny is fine where he is. You`re problems with Sonny are probably misguided with Financial institutions and the SEC.
Who is listed there:
Medtronic?
Smith and Nephew?
J&J?
Freaking Coors????
No wonder Zimmer is all over there not denying a buy out rumor. What if this Zimmer buyout rumor is controlled opposition. To paint it where Amedica desperately needs a Buyout, when in fact it's Zimmer that desperately needs a Buyout? Yes if Zimmer can't play "let's make a deal" Theyre done. Kiss them good bye. They dont even manufacture ceramic. they have a contract with ceramtec. Remember what Sonny said on the CC about why he made a deal with CTL. they did not object to licensing other licensing deals for other companies. If Zimmer gets their hands on this it wont be an exclusive. They could hand amda all their monies and it wouldnt be enough for an exclusive.
No Zimmer. No Ceramtec listed here. In my opinion Zimmer is done son. Put a fork in her.
Microstructure of Spark Plasma-Sintered Silicon Nitride Ceramics.
Bacteriostatic behavior of surface modulated silicon nitride in comparison to polyetheretherketone and titanium.
Citations: Bock RM, Jones EN, Ray DA, B Bal S, Pezzotti G, McEntire BJ.
https://www.americanelements.com/company.html
And there's Thermofisher Scientific listed.
There's definitely a connection here. Not saying they ripped off Ashok for his patents and running around infringing them.
Really would like to hear your opinion on American Elements running around with all ashok's tech stating they 3d print silicon nitride medical products. Another thing I notice is their south american location is in Brazil. Couple of days ago it was Sonny so stupid for attempting to enter the south american market here.
Brazil
American Elements BrazilSao Paolo - (SP), 01204-000 BRAZILTelephone +55 11 3197-6587brazilianservices@americanelements.com
https://www.americanelements.com/additive-manufacturing-3d-printing
also here: see additive manufacture for medical:
It lists Silicon Nitride.
So you think C+CSC is 99% pure silicon nitride? I dont know the cost of HA tricalcium phospates based porous ceramics. It seems like corral. All you`re doing when you combine silicon nitride, HA and tricalcium phosphate is creating a superior bioglass with the addition of Nitrogen which imparts the antibacterial properties and strengthens the glass.
another closely linked topic:
https://www.americanelements.com/company.html
look at the companies being recognized here. Lost of reoccurring names on our end.
https://www.americanelements.com/space-industry.html
Now here. This should be Ashok's patent. This is what his patent directly details. The use of Molydenum oxide for radiation shields. Here's his company. He better be pulling income from these american elements guys. Also a manufacturer of Pure SiNi ceramic filters. (porous ceramic.)
http://bloxr.com/
Comparing the 'alleged' Zimmer H1 implant and C+CSC. Notice on H1 the,what i assume, Hydroxyapatite tricalcium phosphate coating on the bone fusion surfaces. This suggests to me poor fusion rates of Aluminum oxide ceramic. Not trying to throw AMDA under the bus on trade secrets, but looking at C+CSC I would expect a darker color if the porous insert was pure Silicon Nitride. Doped synthetic allograft material would add certain advantages over the traditional HA +tricalcium phosphate, such as antibacterial. If true we wouldnt need a research study to determine advantages between genoss and C+CSC in my opinion. It would be pretty obvious C+CSC would outcompete.
Yup, Loaded more here and stuffing my pillow full of them. Riding the mechanical bull where ever it takes me. They'll have to rip these shares from my cold dead hands until full market share replacement of all sectors. Anything else would be taking profit too early in my opinion.
Corrosion being worse than wear particulate. This is like solid lead vs. White powder lead oxide in lead paint. The oxide form is more bioavailable thus more toxic. This is another reason I think pushing toward metal oxide based ceramics is not a good move. Especially with Amedica patents trying to solve material phase changes in vivo to prevent implant failure from cracking. Suggests the ceramic can degrade to it's base elements and become bioavailable like SiNi. That would be 80% aluminum oxide that accumulates in the bones weakening them thus hard to detect in urine.
Unless they already have SiNi joints for the space robots controlled by the hivemind AMD is building. LOL
https://encrypted-tbn0.gstatic.com/images?q=tbn:ANd9GcRSGq_F0NJDyqozngMxUemdeK84VOzW9HYREGA2u3qp3JQAeZxB_w
http://www.caltech.edu/news/ceramics-dont-have-be-brittle-43680
https://previews.123rf.com/images/godruma/godruma1602/godruma160200039/52243734-sacred-geometry-design-elements-alchemy-religion-philosophy-spirituality-hipster-symbols-and-element.jpg
I was wondering what might happen if they started incorporating the ideas of sacred geometry into these lattice works. I`m sure they considered sacred geometry a branch off of regular geometry. Without which,the pyramids would not have been built and the root concepts of western geometry would not exist. The idea that that the 3rd dimension arises from the 2 dimensional was an integral concept developed here. With a name like metatron who supposedly got beamed up I figure it's worth a shot. Perhaps we are currently unaware of what pattern to adopt where. With the advent of electron microscopes I don't see any orderly patterns within bones beyond a reoccurring random pattern through out nature of various sized holes. Possibly a waste of time diving into.
And you see how the investor is rewarded, with the exception of AMD. Has there ever been a noteworthy investor with a focus on technological advancement besides the DOD and DOE? sidenote: AMD pulled DOE funding. My guess is to lock them in as a US co. as once they took the money theyre not allowed to sell out to another nation.
Now you're going to talk bad about McEntire? sheesh. OTC might as well be the kiss of death. America tries to draw the brightest minds from around the world. At this point if you got a bright Idea, It's looking like a better option to take that idea to China to have it gov. funded and let them have a 90% stake then be forced onto OTC. That,in my opinion, should be a major issue to economic national security, especially with a focus on outsourcing of IPR&D. I see alot of great ideas and break throughs just left by the wayside instead of staying the course in this country. All that tech. dev. amounts to a magazine article. A reality we'll never see.