Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
Would be nice to shut the 👺s up!
It's absolutely FUD when the evidence has been presented, but FUDsters continue to dismiss it.
Read carefully...
If calling out all the FUDsters is a clown show, then I'm guilty... as there are many of you here. 👺
Somebody has to do it.
That's absolute hogwash! If endpoints weren't all met they wouldn't continue to stand behind their claims after a year.
FUDsters choose to ignore that ORs are also valid methods to analyze data and were included in the SAP.
Enough of the nonsense!
Please let us know which spin post you plan to drop when the Excellence results come out for your 👺 act.
There's a lot that's being measured. We'll see how much they include into the TLR...
Outcome Measure Measure Description Time Frame
RSBQ Change from baseline to End of Treatment (EOT) in the Rett Syndrome Behaviour Questionnaire (RSBQ) Total score 12 weeks
Incidents of Adverse Events Change from baseline to End of Treatment (EOT) 12 weeks
Secondary Outcome Measures
Outcome Measure Measure Description Time Frame
CGI-I Change from baseline to End of Treatment (EOT) in the Clinical Global Impression Improvement Scale (CGI-I) score 12 weeks
Anxiety, Depression, and Mood Scale (ADAMS) Anxiety, Depression, and Mood Scale (ADAMS) 12 weeks
Motor Behavioral Assessment-7 dynamic pediatric items (MBA-Ped7) Motor Behavioral Assessment-7 dynamic pediatric items (MBA-Ped7) 12 weeks
Children's Sleep Habits Questionnaire (CSHQ) Children's Sleep Habits Questionnaire (CSHQ) 12 weeks
Seizure Frequency via seizure diary Seizure Frequency via seizure diary 12 weeks
Incidence of Adverse Events Incidence of Adverse Events 12 weeks
RSBQ Emotional Factor-Pediatric (subset of the RSBQ) RSBQ Emotional Factor-Pediatric (subset of the RSBQ) 12 weeks
Rett Syndrome Caregiver Inventory Assessment (RTT CIA) Rett Syndrome Caregiver Inventory Assessment (RTT CIA) 12 weeks
Child Health Questionnaire-Parent Form 50 (CHQ-PF50) Child Health Questionnaire-Parent Form 50 (CHQ-PF50) 12 weeks
Other Outcome Measures
Outcome Measure Measure Description Time Frame
Glutamate Plasma Concentration Glutamate Plasma Concentration 12 weeks
GABA Plasma Concentration GABA Plasma Concentration 12 weeks
Genetic variant SIGMAR1, COMT Genetic variant SIGMAR1, COMT 12 weeks
Maximum Plasma Concentration [Cmax] Number of participants with treatment-related adverse events as assessed by CTCAE v5.0 12 weeks
Maximum Plasma Concentration [Cmax] relationship with RSBQ Number of participants with positive Maximum Plasma Concentration [Cmax] relationship with RSBQ 12 weeks
Other Amino Acid Plasma concentrations Other Amino Acid Plasma concentrations 12 weeks
Measure of gene DNA variants and gene RNA expressions Number of participants with active dose compared gene DNA variants and gene RNA expressions 12 weeks
So much for honest work. 👺
As long as everyone here knows, is all that counts.
I see you're making your FUD attack plans...
Hey FUDman. The condition was if the NDA was filed by June.
Do the handlers have you burning the midnight oil?
Not sure why you're wasting your time debating a paid FUDster on a frivolous topic.
Again, the point being that none of the cabal's ambulance chasers have pursued such frivolous lawsuits when, according to all the FUDsters, the trial didn't meet endpoints (counter to the company's claim). Just goes to show that the FUDsters only speak lies to support their nonsense narrative.
Explain, really? You do realize that his postings and information always come with a slant, a twist, usually with false inferences to support a particular narrative.
It's not lack of proof; it's lack of acceptance by team FUD...
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=173504581
Then perhaps a past life you lived... as you do like to talk about yourself a lot.
You likely described yourself quite well. Congrats!
Insults from paid FUDsters mean nothing to me. The data speaks for itself... and FUDsters lie.
You don't think that the RAs have oversight of the trial plan and SAPs?
You don't know what you're talking about.
Says the msg board clown.
It's in the SAP is all that matters. You trying to FUD your way through some made-up SAP hierarchy is laughable.
The cabal's ambulance chasers can fabricate any such lawsuit filing, like they did in 2015.
They could've easily filed a suit on the basis that the company failed to present the data to support its claim that the trial met all endpoints... unless of course they believe the company actually did present sufficient data... which it did.
You have no clue... just FUD.
Ambulance chasers are notorious for filing frivolous lawsuits (e.g. 2015), but not one was filed when the company PR'd that all endpoints were met, even though shareholders were impacted by the price decline. Bottom line: The cabal's attorneys knew who was behind the attack.
This:
Oh, but there was associated damage to shareholders in share price decline... but not from the data, but by the collusive cabal attack, accompanied by a FUD narrative that said the endpoints weren't met.
Basically, the cabal knows very well who was behind the share price decline and, therefore, no lawsuits ensued.
Your arguments are quite weak.
Poor word choice... I fixed it for you: "I'm MOST certain..."
However, you are completely wrong! Where are all the lawsuits by the conspirators?
You know as well as I, the scumbags would be all over Anavex if they thought the company lied.
You're floundering big time!
I'm most certain that the EMA concurs with Anavex's claims that all endpoints were met, especially when considering the SPA data that demonstrates how >3x of treated patients actually IMPROVED compared with placebo... this in addition to the mean score comparisons that were stat. sig.
If the company isn't being truthful, then where are all the lawsuits? There should be dozens of them, especially from the ambulance chasers.
The additional analysis of the data, with p values < .025, is just further evidence of the efficacy.
Yes, there is more than one way to demonstrate the success of the P2b/3 AD trial and Anavex provided it.
The twisted narrative that you try to sell is simply FUD and nothing more.
Always hedging your false narratives, aren't you?
You're becoming more of a joke by the day.
What a bunch of bullschitt...
Seems the collusive HF cabal are stuck waiting for the next shoe to drop. They can't really short more now, because news could drop at any time. It's best to short after the buying dries up... and so they wait. FUDsters sit impatiently waiting for the new Rett data to drop so they can attack it with more made-up lies and twisted narratives. So, all they have in the interim is to whine about the CEO and how he can't deliver anything on time.
We're anxious to see how team FUD plan to attack the Rett data. Most likely it'll include such nonsense as, "they moved the goalposts again", or "changed the endpoints", or "more cherry picking", or "flawed data", or "fumbled TLR PR", etc. Whatever it is, it'll be the same old tired phrases and drivel we've all seen before. So, when it happens, be ready to buy on the orchestrated takedown.
This is a public service announcement.
...and birds of a feather FUD together.
Merry Christmas to all true longs, who seek and speak truth and have stayed the course... as His way is TRUTH!
May those that don't speak truth experience the haunting from the ghost of Christmas future in the reality of a bright and successful one with Anavex. Truth!
Says the FUDster extraordinaire... the Grand Poobah of the FUD Buffalos.
So, how many millions of shares are needed for the HF handlers to cover their shorts?
Several working overtime to get that holiday pay!
I know of one other biotech that has been relentlessly attacked by the same lying AF HF cartel.
Its personalized cancer vaccine will be granted approval by mid next year.
The collusive HF cartel needs shares to cover!
I'm just here to call out the paid FUDsters 👺... It's a msg board service I provide free of charge.
It's clearly a job assignment to FUD nonstop daily, plus weekends. Perhaps time and a half for holidays.
The company clearly stated in a Q&A that Odds Ratios were part of the SAP; therefore, the claim that all endpoints were met was accurate. Keep in mind, this was only needed for ADL, as Cog and CDR also met endpoints with stat. sig. means comparisons.
To reiterate... the Odds Ratios identified those patients who were strong responders in exhibiting significant IMPROVEMENTS compared to placebo... greater than 3x as many!
Whenever a MB Doc soft bashes, I am skeptical.
It seems rather obvious that the anticipated timeline per protocol has slipped beyond the expected. Perhaps due to late reporting from patients or delays in delivering the data, much like what happened prior to the 2022 CTAD presentation. There are lots of sites that need to provide their data and some are more prompt and efficient than others.
I'm sensing that the increased FUDing on this manipulated takedown is due to the collusive HFs needing shares to cover their collusive short positions. I suppose they all got their marching orders from headquarters... STEP IT UP!
The only conscience that FUDsters have is greed... corrupt greed.