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SHORT SQUEEZE for AVXL coming soon!!!
Good luck and GOD bless
Vast majority” of EV batteries will outlast electric vehicles: study
https://www.teslarati.com/ev-batteries-will-outlast-electric-vehicles-study/
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Expect nearly 8 million shares or more of AVXL stock to be bought this week and at a high for the week!!!
Good luck and GOD bless,
Expect AVXL to close at or near the high of the day, today!!!
Good luck and GOD bless,
As can be seen when viewing the following video, Dr Missling exhibits quite a deal of confidence in using blarcamesine and a treatment for Alzheimer's
https://journey.ct.events/view/b72fd686-0547-49f0-ab66-b1e4959753a1
Thank you Pasakorius on stocktwits for the link.
Good luck and GOD bless,
Fed cuts interest rates by a half-point
https://www.washingtonpost.com/business/2024/09/18/fed-meeting-interest-rate-cut-decision-live-fomc/
That is GREAT NEWS for the US and world economies and GREAT NEWS for AVXL stock.
Good luck and GOD bless,
Doc328: Do you believe that the following is in general true or false???
Anavex 3-71 Phase 2 schizophrenia trial
There are approximately 24 million people worldwide who have schizophrenia.
Also, remember that BMS paid over $12 Billion to acquire KarXT from Karuna and remember also the KarXT is somewhat similar to Anavex 3-71 in that KarXT activated the muscarinic M1 and M4 receptors. Remember that Anavex 3-71 activates the muscarinic M1 and also the sigma-1 receptors.
https://www.anavex.com/_files/ugd/850d88_80ed72201c1f4173a87f87a09470aa46.pdf
Good luck and GOD bless,
🇺🇲
Anavex 3-71 is a PAM for the CHRM1 positive allosteric modulator with agonistic effects as well as a sigma-1 receptor agonist.
This should be quite beneficial for the Phase 2 schizophrenia trial.
A growing understanding of the role of muscarinic receptors in the molecular pathology and treatment of schizophrenia
Expect over 8 million shares of AVXL to be bought this week!!!
Good luck and GOD bless,
NEWS regarding AVXL
https://www.rocketnews.com/2024/09/anavex-life-sciences-reports-advances-for-oral-alzheimers-disease-medication-in-phase-iib-iii-trial/
From Earldog on Stocktwits
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Expect the AVXL share price to close this week SUBSTANTIALLY higher and possibly double or MORE than the current price,
Good luck and GOD bless,
Expect GREAT NEWS for Anavex life Sciences THIS WEEK!!!
Good luck and GOD bless,
Tesla Model 3 becomes Singapore’s best-selling sedan in August 2024
https://www.teslarati.com/tesla-model-3-singapore-best-selling-sedan-august-2024/
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Interest Rates Are Too High. The Fed Should Cut by a Half Point
From the Wall Street Journal
https://www.wsj.com/economy/central-banking/interest-rates-are-too-high-the-fed-should-cut-by-a-half-point-e7855ea8
This will be GREAT NEWS for the US and world economies and GREAT NEWS for AVXL stock.
Good luck and GOD bless,
BIG NEWS for Anavex Life Sciences during October 2024
Pre-specified SIGMAR1 Gene Variant Analysis in Phase IIb/III Trial Supports Precision Medicine Mechanism of Action (MoA) with Improved Treatment Effect of Blarcamesine in Early Alzheimer Disease
Marwan N. Sabbagh 1, Juan Carlos Lopez-Talavera 2, Kun Jin 2, William Robert Chezem 2, Christopher U. Missling 2
1Barrow Neurological Institute - Phoenix (United States), 2Anavex Life Sciences - New York (United States)
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Tesla announces 100 millionth 4680 battery cell production milestone
https://www.teslarati.com/tesla-announces-100-millionth-4680-battery-cell-production-milestone/
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GREAT NEWS NEXT WEEK!!!
https://finance.yahoo.com/news/live/stock-market-today-stocks-rise-with-jumbo-fed-cut-back-on-the-table-133138258.html
This will be great news for the US and world economies and for AVXL stock.
Good luck and GOD bless,
Expect AVXL to close at or near the high of the day, today!!!
Good luck and GOD bless,
Tesla Cybertruck sales surge ~61% in July, outsells direct rivals
https://www.teslarati.com/tesla-cybertruck-sales-61-percent-july-outsells-all-rivals-sp-global-mobility/
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Amyloid Plaques May Not Cause Alzheimer’s: New Research Challenges Decades-Old Theories
https://scitechdaily.com/amyloid-plaques-may-not-cause-alzheimers-new-research-challenges-decades-old-theories/
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The following is NOT true:
Anavex's blarcamesine and/or Anavex 3-71 has a HUGE market
>$20 Trillion
Cumulative costs of Alzheimer’s and dementia care from 2015 to 2050
1 in 3
Medicare dollars will be spent on people living with Alzheimer’s and other dementias in 2050
>11M
The number of Americans providing unpaid care for people with Alzheimer’s or other dementias
https://www.anavex.com/_files/ugd/79bcf7_e5426a3b0863470aacd26f27e5fc4ae3.pdf
Good luck and GOD bless,
September 2024 Presentation from Anavex Life Sciences
https://www.anavex.com/_files/ugd/79bcf7_e5426a3b0863470aacd26f27e5fc4ae3.pdf
Good luck and GOD bless,
Tesla Giga Texas fills with Cybertrucks as Q3 enters its final weeks
Blarcamesine is a sigma 1 receptor agonist that was shown to have positive effects in the mouse model of RTT tested through the IRSF Scout program (Rettsyndrome.org foundation Scout Program and performed by PsychoGenics, Inc.). In animal models, the sigma 1 receptor agonist improved homeostasis in the CNS with increased synaptic development, increased GABA (gamma aminobutyric acid) and BDNF (brain-derived neurotrophic factor), and led to a reduction in seizures and markers of neurodegeneration [73].
This led to three human trials: a phase 2 trial in adults in the US (NCT03758924), a phase 3 trial named the AVATAR trial in adults in Australia (NCT03941444) and a phase 2/3 trial in children, the EXCELLENCE trial, in Australia, UK, and Canada (NCT04304482). The AVATAR trial involved 20 adults receiving Anavex 2-73 and 13 receiving the placebo. The primary outcome measure was the RSBQ scale and secondary measures included the CGI-I and the ADAMS scale of emotional behavior. The RSBQ demonstrated clinically meaningful improvement [(p = 0.037; Cohen’s d effect size of 1.91 (very large)] in 72.2% on Anavex 2-73 versus 38.5% on placebo. In terms of the secondary endpoints, the ADAMS scales showed meaningful improvement in 52.9% on treatment versus 8.3% on placebo (p = 0.010; Cohen’s d effect size of 0.61). The CGI-I showed similar meaningful improvement to the RSBQ (p = 0.037; Cohen’s d effect size of 1.91). Safety data revealed no significant adverse effects versus placebo other than lethargy or sedation.
The third trial with this product, the EXCELLENCE trial in children with RTT, was a phase 2/3 study conducted in Australia, UK, and Canada. The primary outcome measure was the RSBQ completed by the caregivers whereas the secondary outcome measure was the clinician-completed CGI-I. This trial ended in June 2023 and according to a media release on 2 January 2024, the RSBQ failed to achieve significant differences between placebo and study groups, perhaps related to a higher response in the placebo group
https://link.springer.com/article/10.1007/s40263-024-01106-y
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AVXL closed very very near the high of the day, today!!!
Good luck and GOD bless,
Expect AVXL to close at or near the high of the day, today!
Good luck and GOD bless,
Within one week from today AVXL will make a huge move upward in share price!!!
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Tesla (TSLA) gets “Buy” rating and $295 price target from Deutsche Bank
https://www.teslarati.com/tesla-tsla-buy-rating-295-price-target-deutsche-bank/
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Blarcamesine Shows Significant Slowing of Alzheimer Disease in Phase 2/3 Trial
Anavex's blarcamesine and/or Anavex 3-71 as treatments for ischemic stroke
******************************
Sigma-1 receptor signaling: A potential therapeutic approach for ischemic stroke
Alex Ngo 1 , Nikolai Fattakhov 1 , Michal Toborek 1 2
1 Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL, USA.
2 Institute of Physiotherapy and Health Sciences, The Jerzy Kukuczka Academy of Physical Education, Katowice, Poland.
PMID: 39246093 DOI: 10.1177/0271678X241281547
Strokes constitute over 50% of all neurological diseases, standing as the foremost cause of physical and mental disability. Currently, there are no widely accepted gold standard treatments for ischemic strokes beyond intravenous thrombolysis and mechanical thrombectomy applied during the acute therapeutic window. Therefore, the need for novel treatments targeting crucial signaling mediators involved in ischemic stroke is of utmost importance. The sigma-1 receptor (S1R), a molecular chaperone located at mitochondria-associated endoplasmic reticulum membranes (MAM), has exhibited neuroprotective effects when modulated by synthetic and endogenous agents across various cerebrovascular diseases. In this review, we describe the emerging therapeutic role of S1R agonists and antagonists in regulating blood-brain barrier (BBB) dysfunction, neuroinflammation, and neurocognitive impairment following ischemic stroke.
https://pubmed.ncbi.nlm.nih.gov/39246093/
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Tesla Giga Shanghai operating at maximum capacity
https://www.teslarati.com/tesla-giga-shanghai-operating-maximum-capacity-elon-musk/
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The big news came through today right as scheduled.
Anavex Life Sciences has a great pipeline of drugs with a great number of milestones scheduled to occur during the next 4 months.
GOD bless,
The Phase 2 trial using Anavex 3-71 to treat schizophrenia is ongoing and Anavex expects top level results from that trial soon, probably this year in 2024.
Anavex Life Sciences is very excited about this Phase 2 trial.
Good luck and GOD bless,
Late-Stage Alzheimer’s Pipeline Goes Beyond Amyloid and Tau
September 9, 2024
https://www.biospace.com/drug-development/late-stage-alzheimers-pipeline-goes-beyond-amyloid-and-tau
Apparent Tesla Robotaxi training vehicle sightings are inreasing
https://www.teslarati.com/apparent-tesla-robotaxi-training-vehicle-sighting-photos/
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The vast majority of posts on this AVXL discussion board were made by bashers, FUDsters and/or shorters. They are just spewing there negative lies.
Hmmm!!!
Wonder why???
Tesla wireless charging patent revealed ahead of Robotaxi unveiling event
https://www.teslarati.com/tesla-wireless-charging-patent-robotaxi/
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