Replies to post #85596 on NanoViricides Inc. (NNVC)

[Rawnoc]

You are correct on that. Still, it would have been helpful if it was mentioned by NNVC what percentage of rodents croaked so far instead of just saying "not 50%."

[cfoofme]

Yes, even I knew this, so why is there a question? Perhaps NNVC can use a hammer and kill the other 50%,lol.

The therapeutic index (also known as therapeutic ratio) is a comparison of the amount of a therapeutic agent that causes the therapeutic effect to the amount that causes death (in animal studies) or toxicity (in human studies).[1]

Quantitatively, it is the ratio given by the lethal or toxic dose divided by the therapeutic dose.

In animal studies, the therapeutic index is the lethal dose of a drug for 50% of the population (LD50) divided by the minimum effective dose for 50% of the population (ED50).

Lethality is not determined in human clinical trials; instead, the dose that produces a toxicity in 50% of the population (TD50) is used to calculate the therapeutic index.