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Re: Rawnoc post# 85593

Wednesday, 03/26/2014 3:52:45 PM

Wednesday, March 26, 2014 3:52:45 PM

Post# of 146246
The quote is out of context or simply being misunderstood by RawNoc. Dr. S statement refers to the therapeutic index which is explained further along in his exchange. (See below) FluCide is so non-toxic NanoViricides is having a very difficult time finding the dose that will kill 50% of test population.


The therapeutic index (also known as therapeutic ratio) is a comparison of the amount of a therapeutic agent that causes the therapeutic effect to the amount that causes death (in animal studies) or toxicity (in human studies).[1]

Quantitatively, it is the ratio given by the lethal or toxic dose divided by the therapeutic dose.

In animal studies, the therapeutic index is the lethal dose of a drug for 50% of the population (LD50) divided by the minimum effective dose for 50% of the population (ED50).

Lethality is not determined in human clinical trials; instead, the dose that produces a toxicity in 50% of the population (TD50) is used to calculate the therapeutic index.
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