Replies to post #23510 on Amarin Corp Plc (AMRN)

[Biobillionair]

No point arguing which came first, the chicken or the egg. LDL left unchecked leads to plaque buildup. Triglycerides leads to Metabolic Disease, android obesity, and Insulin resistance. Low EPA/AA ratio lead to inflammatory Eicosanoids. They all dance together in complex pathways...Vascepa happens to be the ONLY drug that doesn't step on any toes.

[drrc1949]

LDL-C and TGs DO NOT CAUSE the inflammation, the low ratio of Eicosapentaenoic Acid to Arachidonic Acid resulting from our Atomic Age diets causes the inflammation. Everything that follows in terms of Immune Response exacerbates the initial vascular damage caused by Chronic Inflammation.