To be fair, the effects on dogs sound mild (though use of the words "biologically significant" is not necessarily a mild term). I mean basically the dogs had an increase in the number of red blood cells. In racing circles people take drugs like epogen to accomplish the same thing, haha.
Looking up each of the side effects listed in dogs it really does not sound like anything "toxic" happened at all.
Bucaneer, I take back what I said. Maybe we don't hit a MTD ever :)