Innovation Pharmaceuticals Inc (IPIX)

[Truthbythought]

There is a toxicity and only time will tell where that toxicity turns to MTD. One thing to remember is that for the mice who received chemo as a control in the preclinical trials, the dose of the chemo chosen was "equitoxic" (meaning it had equivalent toxicity in the mouse to 200mg/kg of K)

Also note that the dogs did seem to hit a MTD (depending on how severe the biologically significant changes were) at 60mg/kg, per the below from the posters

"biologically significant decrease in MCHC and increases in RBC, hematocrit, and sodium (high dose)"

I am done converting that to a human dose because we seem to be dealing with an unknown scale, but it means there is a limit. We will just have to see where that is.