" The big HOPE would be late 2015 interim numbers are overwhelming, if not the wait is 4 years."...I believe that JZ is being conservative with the time estimates for Reduce it. I'm hoping for interim results in 2014 and end results in 2015. That said, I don't believe we can afford to fund Reduce it at present levels and need to take whatever measures are necessary to reduce our expenditures in this and all other aspects of the business to conserve cash.