JL, is this an over reaction? In searching for an EPA:AA blood test, to track my ratio, I came across numerous Endocrine, CV, and diet related research. The evidence points to less chronic disease conditions with ratios of 1:1.7 to 1:3. While most on a Western diet are 1:25, the Japanese population has a considerably lower ratio closer to 1:3 and less chronic inflammation diseases, including CV disease.
Amarin should consider filing an sNDA for Vascepa to treat high EPA:AA ratios based on the massive scientific data and epidemiology comparisons with inflammatory diseases. The filing would not be based on one specific disease, but on a dietary deficency causing diseases just as bad as scurvy. I think we have all been lost in the forest, only seeing the trees of cardiovascular disease.
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