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TheProgressive

03/08/13 4:43 PM

#26186 RE: MinnieM #26182

Nothing but absolute confidence. I love it.

TheProgressive

03/08/13 4:45 PM

#26187 RE: MinnieM #26182

Dr Menon and company must REALLY like what they see with Kevetrin so far if they are this confidently and openly talking about phase 2/3 studies and breakthrough therapy designations...awesome!

BonelessCat

03/08/13 4:49 PM

#26189 RE: MinnieM #26182

This is the meat:

The data from the studies affirm that Kevetrin may be useful in a new tumor type, in addition to the other indications that we are studying. Kevetrin has delivered robust results against all indications tested to date. Cellceutix’s strategy is to have multiple trials ongoing against multiple cancer types concurrently. We are conducting testing against several more cancers to delineate the quickest path to market to build corporate and shareholder value.”


Since he refers to "data from the studies" can we assume he also includes human testing in that data? If so, the "robust results" might be signaling they have data that aligns with animal testing including efficacy at low doses.

P53dragon

03/08/13 4:57 PM

#26190 RE: MinnieM #26182

Thanks KarinCA! Your well written article on SA was one reason that I "discovered" ctix.

Agree with others on the sentiment that if the management does not see very high likelihood that the current phase 1 will pan out, they probably will have second thoughts lining up other ducks this early. Since Dr Menon is as seasoned veteran researcher as it comes, his enthusiasm and aggressive planning is quite meaningful.

So ctix is planning to use the current phase 1 result on renal cancer to springboard other cancer studies into phase 2/3, through some new FDA initiatives?

Astavakra

03/08/13 5:02 PM

#26192 RE: MinnieM #26182

Given the limited treatment options, devastating effects, and small patient population, Cellceutix believes that retinoblastoma would make an excellent candidate for a phase 2/3 trial once our present phase 1 trial is completed. It would qualify for a number of FDA programs (Orphan, Fast Track and Breakthrough) that can exponentially shrink development time, should clinical data support the current research.


So perhaps the strategy is to fasttrack Kevetrin via an unmet need route in the treatment of retinoblastoma and then let the tail wag the dog, as it were.

biomanbaba

03/08/13 5:19 PM

#26201 RE: MinnieM #26182

“While our Phase 1 clinical trial is ongoing, we are planning for future trials that are aimed directly at the latest initiatives of the Food and Drug Administration to expedite development of ‘breakthrough’ technologies to commercialization,” commented Dr. Krishna Menon, Chief Scientific Officer at Cellceutix. “The data from the studies affirm that Kevetrin may be useful in a new tumor type, in addition to the other indications that we are studying. Kevetrin has delivered robust results against all indications tested to date. Cellceutix’s strategy is to have multiple trials ongoing against multiple cancer types concurrently. We are conducting testing against several more cancers to delineate the quickest path to market to build corporate and shareholder value.”



that is worth a hot diggetty damn

a1derfullife

03/08/13 5:49 PM

#26213 RE: MinnieM #26182

What's nice about this latest study is not just the result in retinoblastoma, but the empirically observed correlation (in other drugs) between efficacy against multiple cancer lines in animal studies, and efficacy in humans. In other words, other drugs that have been effective against multiple cancer lines in mice have had a much higher success rate in clinical studies than have drugs that have been effective against only a few cancer lines. As the positive pre-clinical studies for K continue to climb, so does my confidence that the clinical studies will be successful as well.

A1

starbuxsux

03/08/13 7:46 PM

#26242 RE: MinnieM #26182

Awesome...only focused on is this sentence: Kevetrin has delivered robust results against all indications tested to date.

I'm sleeping good tonight...

TheDane

03/08/13 8:06 PM

#26244 RE: MinnieM #26182

Holy cow! That's a total gross-out! Hopefully it's good news, though.

farrell90

03/08/13 11:25 PM

#26261 RE: MinnieM #26182

Sport fans may remember NBA player Derek Fischer leaving a playoff game to be with his infant daughter who was receiving intraarterial chemotherapy for retinoblastoma. She was one of the first to receive this innovative treatment. Below is an article about one of her Sloan Kettering's physicians. At the bottom of the article are links to other stories describing her treatment.

Imagine how much better it would be to receive an effective, safe and nontoxic treatment such as oral Kevetrin. Farrell

http://www.mskcc.org/multimedia/new-intraarterial-chemotherapy-treatment-used-treat-basketball-star-daughter

David H. Abramson, MD

Chief, Ophthalmic Oncology Service, Department of Surgery
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I am a board-certified ophthalmologist with specialty training in opthalmic oncology. I am Chief of the Ophthalmic Oncology Service at Memorial Sloan-Kettering Cancer Center, the only service of its kind dedicated to ophthalmic oncology in a cancer hospital in the US. Because of our close association with specialists in pediatrics, radiation oncology, and medicine, we are able to offer coordinated, state-of-the-art care with access to novel therapies and clinical trials not available anywhere else in the country.

Ophthalmic oncologists are ophthalmologists who specialize in the diagnosis and treatment of cancer on the surface of the eye, in the eye, and in the tissues around the eye (the lids and orbit). I have a joint appointment in Surgery, Pediatrics, and Radiation Oncology.

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