IFN intolerant in my interpretation simply means having experienced IFN previously and not having tolerated it well - this has little to do with one's IL28b status.
You are right of course that it is known for some time now that IL28B status is an irrelevant factor when you treat HCV with a potent DAA combo and perhaps (not sure about that) GILD were still genotyping the IL28 locus, but even if so, it would be a response predictor for INF containing treatment (predicts viral clearance) not INF intolerance. So my feeling is that these patients are a bit more intolerant to treatments in general and naïve comply better.
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